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Acta Orthopaedica Volume 89, 2018 - Issue 5
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Articles

Midterm risk of cancer with metal-on-metal hip replacements not increased in a Finnish population

Elina EkmanDepartment of Orthopaedics and Traumatology, Turku University Hospital, Turku; Correspondence[email protected]
,
Inari LaaksonenDepartment of Orthopaedics and Traumatology, Turku University Hospital, Turku;
,
Antti EskelinenCoxa Hospital for Joint Replacement, Tampere;
,
Pekka PulkkinenDepartment of Public Health, Helsinki University, Helsinki;
,
Eero PukkalaFaculty of Social Sciences, University of Tampere, Tampere; ;The Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland
&
Keijo MäkeläDepartment of Orthopaedics and Traumatology, Turku University Hospital, Turku;
Pages 575-579 | Published online: 18 Jun 2018

  • AOANJRR. Annual Report 2016. AOANJRR; 2016.
  • Bonassi S, Hagmar L, Strömberg U, Huici Montagud A, Tinnerberg H, Forni A, Heikkilä P, Wanders S, Wilhardt P, Hansteen I L, Knudsen L E, Norppa H. Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. Cancer Res 2000; 60(6): 1619–25.
  • Brewster D H, Stockton D L, Reekie A, Ashcroft G P, Howie C R, Porter D E, Black R J. Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland. Br J Cancer 2013; 108(9): 1883–90.
  • Case C P, Langkamer V G, James C, Palmer M R, Kemp A J, Heap P F, Solomon L. Widespread dissemination of metal debris from implants. J Bone Joint Surg Br 1994; 76(5): 701–12.
  • Case C P, Langkamer V G, Howell R T, Webb J, Standen G, Palmer M, Kemp A, Learmonth I D. Preliminary observations on possible premalignant changes in bone marrow adjacent to worn total hip arthroplasty implants. Clin Orthop Relat Res 1996; (329 Suppl): S269–S79.
  • Christian W V, Oliver L D, Paustenbach D J, Kreider M L, Finley B L. Toxicology-based cancer causation analysis of CoCr-containing hip implants: a quantitative assessment of genotoxicity and tumorigenicity studies. J Appl Toxicol 2014: 939–67.
  • Daley B, Doherty A T, Fairman B, Case C P. Wear debris from hip or knee replacements causes chromosomal damage in human cells in tissue culture. J Bone Joint Surg Br 2004; 86(4): 598–606.
  • FAR. The Finnish Arthroplasty Register (FAR).
  • Freemantle N, Marston L, Walters K, Wood J, Reynolds M R, Petersen I. Making inferences on treatment effects from real world data: propensity scores, confounding by indication, and other perils for the unwary in observational research. BMJ 2013; 347: f6409.
  • Isomäki H A, Hakulinen T, Joutsenlahti U. Excess risk of lymphomas, leukemia and myeloma in patients with rheumatoid arthritis. J Chronic Dis 1978; 31(11): 691–6.
  • Lalmohamed W, MacGregor AJ, de Vries F, Leufkens H, van Staa T. Patterns of risk of cancer in patients with metal-on-metal hip replacements versus other bearing surface types: a record linkage study between a prospective joint registry and general practice electronic health records in England. PLoS One 2013; 8(7): e65891.
  • Langton D J, Jameson S S, Joyce T J, Hallab N J, Natu S, Nargol V F. Early failure of metal-on-metal bearings in hip resurfacing and large-diameter total hip replacement: a consequence of excess wear. J Bone Joint Surg Br 2010; 92(1): 38–46.
  • Levasic V, Milosev I, Zadnik V. Risk of cancer after primary total hip replacement: the influence of bearings, cementation and the material of the stem. Acta Orthop 2018; 89(2): 234–9.
  • Mäkelä K T, Visuri T, Pulkkinen P, Eskelinen A, Remes V, Virolainen P, Junnila M, Pukkala E. Risk of cancer with metal-on-metal hip replacements: population based study. BMJ 2012; 345: e4646.
  • Mäkelä K T, Visuri T, Pulkkinen P, Eskelinen A, Remes V, Virolainen P, Junnila M, Pukkala E. Cancer incidence and cause-specific mortality in patients with metal-on-metal hip replacements in Finland. Acta Orthop 2014; 85(1): 32–8.
  • NJR. NJR 13th Annual Report. NJR 2016.
  • Nyrén O, McLaughlin J K, Gridley G, Ekbom A, Johnell O, Fraumeni J F, Adami H O. Cancer risk after hip replacement with metal implants: a population-based cohort study in Sweden. J Natl Cancer Inst 1995; 87(1): 28–33.
  • Ollivere B, Darrah C, Barker T, Nolan J, Porteous M J. Early clinical failure of the Birmingham metal-on-metal hip resurfacing is associated with metallosis and soft-tissue necrosis. J Bone Joint Surg Br 2009; 91(8): 1025–30.
  • Olsen J H, McLaughlin J K, Nyrén O, Mellemkjaer L, Lipworth L, Blot W J, Fraumeni J F. Hip and knee implantations among patients with osteoarthritis and risk of cancer: a record-linkage study from Denmark. Int J Cancer 1999; 81(5): 719–22.
  • Onega T, Baron J, MacKenzie T. Cancer after total joint arthroplasty: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2006; 15(8): 1532–7.
  • Pandit H, Glyn-Jones S, McLardy-Smith P, Gundle R, Whitwell D, Gibbons C L M, Ostlere S, Athanasou N, Gill H S, Murray D W. Pseudotumours associated with metal-on-metal hip resurfacings. J Bone Joint Surg Br 2008; 90(7): 847–51.
  • Pastides P S, Dodd M, Sarraf K M, Willis-Owen C A. Trunnionosis: a pain in the neck. World J Orthop 2013; 4(4): 161–6.
  • Pijls B G, Meessen J M T A, Schoones J W, Fiocco M, van der Heide H J L, Sedrakyan A, Nelissen R G H H. Increased mortality in metal-on-metal versus non-metal-on-metal primary total hip arthroplasty at 10 years and longer follow-up: a systematic review and meta-analysis. PLoS One 2016; 11(6): e0156051
  • Polyzois I, Nikolopoulos D, Michos I, Patsouris E, Theocharis S. Local and systemic toxicity of nanoscale debris particles in total hip arthroplasty. J Appl Toxicol 2012; 32(4): 255–69.
  • Pukkala E, Engholm G, Hojsgaard Schmidt L, Storm H, Khan S, Lambe M, Pettersson D, Olafsdottir E, Tryggvadottir L, Hakanen T, Malila N, Virtanen A, Johannesen T, Laronningen S, Ursin G. Nordic Cancer Registries: an overview of their procedures and data comparability. Acta Oncol 2018; 57(4): 440–55.
  • Sarhadi V K, Parkkinen J, Reito A, Nieminen J, Porkka N, Wirtanen T, Laitinen M, Eskelinen A, Knuutila S. Genetic alterations in periprosthetic soft-tissue masses from patients with metal-on-metal hip replacement. Mutat Res 2015; 781: 1–6.
  • Shea K G, Lundeen G A, Bloebaum R D, Bachus K N, Zou L. Lymphoreticular dissemination of metal particles after primary joint replacements. Clin Orthop Relat Res 1997; (338): 219–26.
  • Shimmin A J, Back D. Femoral neck fractures following Birmingham hip resurfacing: a national review of 50 cases. J Bone Joint Surg Br 2005; 87: 463–4.
  • Smith A J, Dieppe P, Porter M, Blom A W; National Joint Registry of England and Wales. Risk of cancer in first seven years after metal-on-metal hip replacement compared with other bearings and general population: linkage study between the National Joint Registry of England and Wales and hospital episode statistics. BMJ 2012; 344: e2383.
  • Teppo L, Pukkala E, Lehtonen M. Data quality and quality control of a population-based cancer registry: experience in Finland. Acta Oncol 1994; 33(4): 365–9.
  • Urban R M, Jacobs J J, Tomlinson M J, Gavrilovic J, Black J, Peoc’h M. Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement. J Bone Joint Surg Am 2000; 82(4): 457–76.
  • Visuri T, Pukkala E, Paavolainen P, Pulkkinen P, Riska EB. Cancer risk after metal on metal and polyethylene on metal total hip arthroplasty. Clin Orthop Relat Res 1996; (329 Suppl): S280–S9.
  • Visuri T, Pukkala E, Pulkkinen P, Paavolainen P. Decreased cancer risk in patients who have been operated on with total hip and knee arthroplasty for primary osteoarthrosis: a meta-analysis of 6 Nordic cohorts with 73,000 patients. Acta Orthop Scand 2003; 74(3): 351–60.
  • Visuri T, Pulkkinen P, Paavolainen P. Malignant tumors at the site of total hip prosthesis. analytic review of 46 cases. J Arthroplasty 2006: 311–23.
  • Visuri T, Pulkkinen P, Paavolainen P, Pukkala E. Cancer risk is not increased after conventional hip arthroplasty: a nationwide study from the Finnish Arthroplasty Register with follow-up of 24,636 patients for a mean of 13 years. Acta Orthop 2010; 81(1): 77–81.

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