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Editorial

Future prospects for Antimicrobial peptide development: peptidomimetics and antimicrobial combinations

ORCID Icon & ORCID Icon
Pages 601-604 | Received 10 Jan 2020, Accepted 15 Feb 2021, Published online: 24 Feb 2021

References

  • Magiorakos A-P, Srinivasan A, Carey RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18:268–281.
  • Rosenblatt-Farrell N. The landscape of antibiotic resistance. Environ Health Perspect. 2009;117:A244–50.
  • Abdel Monaim SAH, Ramchuran EJ, El-Faham A, et al. Converting teixobactin into a cationic antimicrobial peptide (AMP). J Med Chem. 2017;60:7476–7482.
  • Greber E, Dawgul M. Antimicrobial peptides under clinical trials. Curr Top Med Chem. 2017;17:620–628.
  • Wang J, Dou X, Song J, et al. Antimicrobial peptides: promising alternatives in the post feeding antibiotic era. Med Res Rev. 2019;39:831–859.
  • Sierra JM, Fusté E, Rabanal F, et al. An overview of antimicrobial peptides and the latest advances in their development. Expert Opin Biol Ther. 2017;17:663–676.
  • Armengol E, Domènech O, Fusté E, et al. Efficacy of combinations of colistin with other antimicrobials involves membrane fluidity and efflux machinery. Infect Drug Resist. 2019;12:2031–2038.
  • Gomes Von Borowski R, Gnoatto SCB, Macedo AJ, et al. Promising antibiofilm activity of peptidomimetics. Front Microbiol. 2018;9:2157.
  • Kuppusamy R, Willcox M, Black DS, et al. Short cationic peptidomimetic antimicrobials. Antibiotics. 2019;8:44.
  • Kokel A, Torok M. Recent advances in the development of antimicrobial peptides (AMPs): attempts for sustainable medicine? Curr Med Chem. 2018;25:2503–2519.
  • Andreev K, Martynowycz MW, Gidalevitz D. Peptoid drug discovery and optimization via surface X-ray scattering. Biopolymers. 2019;110. DOI:10.1002/bip.23274
  • Chan BA, Xuan S, Li A, et al. Polypeptoid polymers: synthesis, characterization, and properties. Biopolymers. 2018;109:e23070.
  • Molchanova N, Hansen PR, Franzyk H. Advances in development of antimicrobial peptidomimetics as potential drugs. Molecules. 2017;22:1430.
  • Sang P, Shi Y, Teng P, et al. Antimicrobial AApeptides. Curr Top Med Chem. 2016;17:1266–1279.
  • Hicks RP, Abercrombie JJ, Wong RK, et al. Antimicrobial peptides containing unnatural amino acid exhibit potent bactericidal activity against ESKAPE pathogens. Bioorg Med Chem. 2013;21:205–214.
  • Iyer VA. Review of stapled peptides and small molecules to inhibit protein–protein interactions in cancer. Curr Med Chem. 2016;23:3025–3043.
  • Andersson DI, Hughes D, Kubicek-Sutherland JZ. Mechanisms and consequences of bacterial resistance to antimicrobial peptides. Drug Resist Updat. 2016;26:43–57. Churchill Livingstone.
  • León-Buitimea A, Garza-Cárdenas CR, Garza-Cervantes JA, et al. The demand for new antibiotics: antimicrobial peptides, nanoparticles, and combinatorial therapies as future strategies in antibacterial agent design. Front Microbiol. 2020;11:1669.
  • Coates ARM, Hu Y, Holt J, et al. Antibiotic combination therapy against resistant bacterial infections: synergy, rejuvenation and resistance reduction. Expert Rev Anti Infect Ther. 2020;18:5–15.
  • Phougat N, Khatri S, Singh A, et al. Combination therapy: the propitious rationale for drug development. Comb Chem High Throughput Screen. 2014;17:53–67.
  • Marquette A, Bechinger B. Biophysical investigations elucidating the mechanisms of action of antimicrobial peptides and their synergism. Biomolecules. 2018;8(2):18.
  • Hollmann A, Martinez M, Maturana P, et al. Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics. Front Chem. 2018;204. DOI:10.3389/fchem.2018.00204
  • Cheng YS, Williamson PR, Zheng W. Improving therapy of severe infections through drug repurposing of synergistic combinations. Curr Opin Pharmacol. 2019;92–98. DOI:10.1016/j.coph.2019.07.006
  • Sen P, Saha A, Dixit NM. You cannot have your synergy and efficacy too. Trends Pharmacol Sci. 2019;40:811–817.
  • Gong H, Zhang J, Hu X, et al. Hydrophobic control of the bioactivity and cytotoxicity of de novo-designed antimicrobial peptides. ACS Appl Mater Interfaces. 2019;11:34609–34620.
  • Rudilla H, Fusté E, Cajal Y, et al. Synergistic antipseudomonal effects of synthetic peptide AMP38 and carbapenems. Molecules. 2016;21:1223.
  • Kumar SN, Lankalapalli RS, Kumar BSD. In vitro antibacterial screening of six proline-based cyclic dipeptides in combination with β-lactam antibiotics against medically important bacteria. Appl Biochem Biotechnol. 2014;173:116–128.
  • Wang Z, Zhang L, Wang J, et al. Synergistic interaction of PMAP-36 and PRW4 with aminoglycoside antibiotics and their antibacterial mechanism. World J Microbiol Biotechnol. 2014;30:3121–3128.

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