43
Views
0
CrossRef citations to date
0
Altmetric
Commentary

Cocrystals development: an approach to improve antiviral efficacy

ORCID Icon, ORCID Icon & ORCID Icon
Received 28 Mar 2024, Accepted 24 May 2024, Published online: 24 Jun 2024

References

  • Woolhouse M, Scott F, Hudson Z, et al. Human viruses: discovery and emeraence. Philos Trans R Soc B Biol Sci. 2012;367:2864–2871. doi:10.1098/rstb.2011.0354
  • Adamson CS, Chibale K, Goss RJM, et al. Antiviral drug discovery: preparing for the next pandemic. Chem Soc Rev. 2021;50:3647–3655. doi:10.1039/D0CS01118E
  • Dhondale MR, Thakor P, Nambiar AG, et al. Co-crystallization approach to enhance the stability of moisture-sensitive drugs. Pharmaceutics. 2023;15:189. doi:10.3390/pharmaceutics15010189
  • Rodrigues M, Baptista B, Lopes JA, et al. Pharmaceutical cocrystallization techniques. Advances and challenges. Int J Pharm. 2018;547:404–420. doi:10.1016/J.IJPHARM.2018.06.024
  • Bolla G, Nangia A. Pharmaceutical cocrystals: walking the talk. Chem Commun. 2016;52:8342–8360. doi:10.1039/c6cc02943d
  • Chen R, Wang T, Song J, et al. Antiviral drug delivery system for enhanced bioactivity, better metabolism and pharmacokinetic characteristics. Int J Nanomedicine. 2021;16:4959–4984. doi:10.2147/IJN.S315705
  • Batisai E. Solubility enhancement of antidiabetic drugs using a co-crystallization approach. ChemistryOpen. 2021;10:1260–1268. doi:10.1002/open.202100246
  • Samsodien H, Bapoo M, Doms TI, et al. FTIR, dissolution and anti-viral activity of nevirapine co-crystals. Pharm Anal Acta. 2017;8(9):561. doi: 10.4172/2153-2435.1000561
  • Bu FZ, Yu YM, Zhang M, et al. Directed self-assembly with gallic acid provides first phenolic acid cocrystals for the antiviral drug acyclovir toward increasing pharmaceutical features and synergy: a theoretical and experimental integration research. Cryst Growth Des. 2023;23:5868–5882. doi:10.1021/acs.cgd.3c00489
  • Hao H, Zhang Y, Hu X, et al. Cocrystallization of 5-fluorouracil with gallic acid: a novel 5-fluorouracil cocrystal displaying synergistic anti-tumor activity both in oral and intraperitoneal injection administration. Eur J Pharm Biopharm. 2023;187:12–23. doi:10.1016/j.ejpb.2023.04.001
  • Wang LY, Niu YY, Zhao MY, et al. Supramolecular self-assembly of amantadine hydrochloride with ferulic acid: via dual optimization strategy establishes a precedent of synergistic antiviral drug-phenolic acid nutraceutical cocrystal. Analyst. 2021;146:3988–3999. doi:10.1039/d1an00478f
  • Wang LY, Zhao MY, Bu FZ, et al. Cocrystallization of amantadine hydrochloride with resveratrol: the first drug-nutraceutical cocrystal displaying synergistic antiviral activity. Cryst Growth Des. 2021;21:2763–2776. doi:10.1021/acs.cgd.0c01673
  • Wang LY, Bu FZ, Li YT, et al. A sulfathiazole-amantadine hydrochloride cocrystal: the first codrug simultaneously comprising antiviral and antibacterial components. Cryst Growth Des. 2020;20:3236–3246. doi:10.1021/acs.cgd.0c00075
  • Gao Y, Gao J, Liu Z, et al. Coformer selection based on degradation pathway of drugs: a case study of adefovir dipivoxil-saccharin and adefovir dipivoxil-nicotinamide cocrystals. Int J Pharm. 2012;438:327–335. doi:10.1016/j.ijpharm.2012.09.027
  • Mahajan S, Choudhary S, Kumar P, et al. Antiviral strategies targeting host factors and mechanisms obliging +ssRNA viral pathogens. Bioorganic Med Chem. 2021;46:116356. doi:10.1016/j.bmc.2021.116356
  • Chavan RB, Thipparaboina R, Yadav B, et al. Continuous manufacturing of co-crystals: challenges and prospects. Drug Deliv Transl Res. 2018;8:1726–1739. doi:10.1007/s13346-018-0479-7
  • Lee T, Chen HR, Lin HY, et al. Continuous co-crystallization as a separation technology: the study of 1:2 co-crystals of phenazine-vanillin. Cryst Growth Des. 2012;12:5897–5907. doi:10.1021/cg300763t
  • Cruz P, Alvarez C, Rocha F, et al. Tailoring the crystal size distribution of an active pharmaceutical ingredient by continuous antisolvent crystallization in a planar oscillatory flow crystallizer. Chem Eng Res Des. 2021;175:115–123. doi:10.1016/j.cherd.2021.08.030
  • Bui M, Chakravarty P, Nagapudi K. Application of resonant acoustic mixing in the synthesis of vitamin C-nicotinamide variable stoichiometry cocrystals. Faraday Discuss. 2022;241:357–366. doi:10.1039/d2fd00124a
  • Kale DP, Zode SS, Bansal AK. Challenges in translational development of pharmaceutical cocrystals. J Pharm Sci. 2017;106:457–470. doi:10.1016/j.xphs.2016.10.021

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.