The use of intense pulsed light therapy in the treatment of refractory meibomian gland dysfunction

References

• Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II definition and classification report. Ocul Surf. 2017 Jul;15(3):276–283.
   PubMed Web of Science ®Google Scholar
• Schaumberg DA, Nichols JJ, Papas EB, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on the epidemiology of, and associated risk factors for, MGD. Invest Ophthalmol Vis Sci. 2011 Mar;52(4):1994–2005.
   PubMed Web of Science ®Google Scholar
• Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II epidemiology report. Ocul Surf. 2017 Jul;15(3):334–365.
   PubMed Web of Science ®Google Scholar
• Mathews PM, Ramulu PY, Swenor BS, et al. Functional impairment of reading in patients with dry eye. Br J Ophthalmol. 2017 Apr;101(4):481–486.
   PubMed Web of Science ®Google Scholar
• Bron AJ, de Paiva CS, Chauhan SK, et al. TFOS DEWS II pathophysiology report. Ocul Surf. 2017 Jul;15(3):438–510.
   PubMed Web of Science ®Google Scholar
• Knop E, Knop N, Millar T, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland. Invest Ophthalmol Vis Sci. 2011 Mar;52(4):1938–1978.
   PubMed Web of Science ®Google Scholar
• Jones L, Downie LE, Korb D, et al. TFOS DEWS II management and therapy report. Ocul Surf. 2017 Jul;15(3):575–628.
   PubMed Web of Science ®Google Scholar
• Geerling G, Tauber J, Baudouin C, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction. Invest Ophthalmol Vis Sci. 2011 Mar 30;52(4):2050–2064.
   PubMed Web of Science ®Google Scholar
• Vora GK, Gupta PK. Intense pulsed light therapy for the treatment of evaporative dry eye disease. Curr Opin Ophthalmol. 2015 Jul;26(4):314–318.
   PubMed Web of Science ®Google Scholar
• Giannaccare G, Taroni L, Senni C, et al. Intense pulsed light therapy in the treatment of meibomian gland dysfunction: current perspectives. Clin Optom. 2019;11:113–126.
   PubMed Web of Science ®Google Scholar
• Dell SJ. Intense pulsed light for evaporative dry eye disease. Clin Ophthalmol. 2017;11:1167–1173.
   PubMed Web of Science ®Google Scholar
• Toyos R, McGill W, Briscoe D. Intense pulsed light treatment for dry eye disease due to meibomian gland dysfunction; a 3-year retrospective study. Photomed Laser Surg. 2015 Jan;33(1):41–46.
   PubMed Web of Science ®Google Scholar
• Prieto VG, Sadick NS, Lloreta J, et al. Effects of intense pulsed light on sun-damaged human skin, routine, and ultrastructural analysis. Lasers Surg Med. 2002;30(2):82–85.
   PubMed Web of Science ®Google Scholar
• Xue A, Wang MTM, Ormonde SE, et al. Randomised double-masked placebo-controlled trial of the cumulative treatment efficacy profile of intense pulsed light therapy for meibomian gland dysfunction. Ocul Surf. 2020;18:286–297.
   PubMed Web of Science ®Google Scholar
• Liu R, Rong B, Tu P, et al. Analysis of cytokine levels in tears and clinical correlations after intense pulsed light treating meibomian gland dysfunction. Am J Ophthalmol. 2017 Nov;183:81–90.
   PubMed Web of Science ®Google Scholar
• Choi M, Han SJ, Ji YW, et al. Meibum expressibility improvement as a therapeutic target of intense pulsed light treatment in meibomian gland dysfunction and its association with tear inflammatory cytokines. Sci Rep. 2019 May 21;9(1):7648.
   PubMed Web of Science ®Google Scholar
• Piccolo D, Di Marcantonio D, Crisman G, et al. Unconventional use of intense pulsed light. Biomed Res Int. 2014;2014:618206.
   PubMed Web of Science ®Google Scholar
• Cuerda-Galindo E, Diaz-Gil G, Palomar-Gallego MA, et al. Increased fibroblast proliferation and activity after applying intense pulsed light 8001200 nm. Ann Anat. 2015 Mar;198:66–72.
   PubMed Web of Science ®Google Scholar
• Gupta PK, Vora GK, Matossian C, et al. Outcomes of intense pulsed light therapy for treatment of evaporative dry eye disease. Can J Ophthalmol. 2016 Aug;51(4):249–253.
   PubMed Web of Science ®Google Scholar
• Vegunta S, Patel D, Shen JF. Combination therapy of intense pulsed light therapy and meibomian gland expression (IPL/MGX) can improve dry eye symptoms and meibomian gland function in patients with refractory dry eye: a retrospective analysis. Cornea. 2016 Mar;35(3):318–322.
   PubMed Web of Science ®Google Scholar
• Ahmed SA, Taher IME, Ghoneim DF, et al. Effect of intense pulsed light therapy on tear proteins and lipids in meibomian gland dysfunction. J Ophthalmic Vis Res. 2019 Jan-Mar;14(1):3–10.
   PubMed Web of Science ®Google Scholar
• Albietz JM, Schmid KL. Intense pulsed light treatment and meibomian gland expression for moderate to advanced meibomian gland dysfunction. Clin Exp Optom. 2018 Jan;101(1):23–33.
   PubMed Web of Science ®Google Scholar
• Arita R, Fukuoka S, Morishige N. Therapeutic efficacy of intense pulsed light in patients with refractory meibomian gland dysfunction. Ocul Surf. 2019 Jan;17(1):104–110.
   PubMed Web of Science ®Google Scholar
• Jiang X, Lv H, Song H, et al. Evaluation of the safety and effectiveness of intense pulsed light in the treatment of meibomian gland dysfunction. J Ophthalmol. 2016;2016:1910694.
   PubMed Web of Science ®Google Scholar
• Karaca EE, Evren Kemer O, Ozek D. Intense regulated pulse light for the meibomian gland dysfunction. Eur J Ophthalmol. 2018 Dec;4:1120672118817687.
   Google Scholar
• Seo KY, Kang SM, Ha DY, et al. Long-term effects of intense pulsed light treatment on the ocular surface in patients with rosacea-associated meibomian gland dysfunction. Cont Lens Anterior Eye. 2018 Oct;41(5):430–435.
   PubMed Web of Science ®Google Scholar
• Yin Y, Liu N, Gong L, et al. Changes in the meibomian gland after exposure to intense pulsed light in meibomian gland dysfunction (MGD) patients. Curr Eye Res. 2018 Mar;43(3):308–313.
   PubMed Web of Science ®Google Scholar
• Rong B, Tang Y, Liu R, et al. Long-term effects of intense pulsed light combined with meibomian gland expression in the treatment of meibomian gland dysfunction. Photomed Laser Surg. 2018 Oct;36(10):562–567.
   PubMed Web of Science ®Google Scholar
• Guilloto Caballero S, Garcia Madrona JL, Colmenero Reina E. Effect of pulsed laser light in patients with dry eye syndrome. Arch Soc Esp Oftalmol. 2017 Nov;92(11):509–515.
   PubMedGoogle Scholar
• Li D, Lin SB, Cheng B. Intense pulsed light treatment for meibomian gland dysfunction in skin types III/IV. Photobiomodul Photomed Laser Surg. 2019 Feb;37(2):70–76.
   PubMed Web of Science ®Google Scholar
• Rong B, Tang Y, Tu P, et al. Intense pulsed light applied directly on eyelids combined with meibomian gland expression to treat meibomian gland dysfunction. Photomed Laser Surg. 2018 Jun;36(6):326–332.
   PubMed Web of Science ®Google Scholar
• Javey G, Schwartz SG, Albini TA. Ocular complication of intense pulsed light therapy: iris photoablation. Dermatologic Surg. 2010 Sep;36(9):1466–1468.
   PubMed Web of Science ®Google Scholar
• Crabb M, Chan WO, Taranath D, et al. Intense pulsed light therapy (IPL) induced iritis following treatment for a medial canthal capillary malformation. Australas J Dermatol. 2014 Nov;55(4):289–291.
   PubMed Web of Science ®Google Scholar
• Mejia LF, Gil JC, Jaramillo M. Intense pulsed light therapy: A promising complementary treatment for dry eye disease. Arch Soc Esp Oftalmol. 2019 Jul;94(7):331–336.
   PubMedGoogle Scholar
• Arita R, Mizoguchi T, Fukuoka S, et al. Multicenter study of intense pulsed light therapy for patients with refractory meibomian gland dysfunction. Cornea. 2019 Feb;38(2):e4.
   PubMedGoogle Scholar
• Dell SJ, Gaster RN, Barbarino SC, et al. Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction. Clin Ophthalmol. 2017;11:817–827.
   PubMed Web of Science ®Google Scholar
• Vigo L, Giannaccare G, Sebastiani S, et al. Intense pulsed light for the treatment of dry eye owing to meibomian gland dysfunction. J Vis Exp. 2019;1:146.
   Google Scholar
• Craig JP, Chen YH, Turnbull PR. Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction. Invest Ophthalmol Vis Sci. 2015Feb12;56(3):1965–1970.
   PubMed Web of Science ®Google Scholar
• Available from: https://clinicaltrials.gov/ct2/show/NCT03396913
   Google Scholar
• Available from: https://clinicaltrials.gov/ct2/show/NCT03518398
   Google Scholar
• Available from: https://clinicaltrials.gov/ct2/show/NCT03089580
   Google Scholar
• Available from: https://clinicaltrials.gov/ct2/show/NCT03265652
   Google Scholar