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Review

Surgical management of macular holes: techniques, outcomes, and treatment of special cases

, & ORCID Icon
Pages 391-403 | Received 12 Dec 2022, Accepted 06 Nov 2023, Published online: 27 Nov 2023

References

  • Evans JR, Schwartz, S. D., McHugh, J. D. A et al. Systemic risk factors for idiopathic macular holes: a case-control study. Eye (Lond). 1998;12(Pt 2):256–259. doi: 10.1038/eye.1998.60
  • Casuso LA, Scott IU, Flynn HW, et al. Long-term follow-up of unoperated macular holes. Ophthalmol. 2001;108(6):1150–1155. doi: 10.1016/S0161-6420(01)00581-4
  • Klein R, Klein BE, Wang Q, et al. The epidemiology of epiretinal membranes. Trans Am Ophthalmol Soc. 1994;92:403–430. discussion 425-30.
  • Gao M, Liu K, Lin Q, et al. Management modalities for traumatic macular hole: a systematic review and single-Arm meta-analysis. Curr Eye Res. 2017;42(2):287–296. doi: 10.1080/02713683.2016.1175021
  • Gass JD. Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol. 1995;119(6):752–759. doi: 10.1016/S0002-9394(14)72781-3
  • Johnson RN, McDonald HR, Lewis H, et al. Traumatic macular hole: observations, pathogenesis, and results of vitrectomy surgery. Ophthalmol. 2001;108(5):853–857. doi: 10.1016/S0161-6420(00)00650-3
  • Ghoraba HH, Leila M, Zaky AG, et al. Results of pars plana vitrectomy for different types of macular holes. Clin Ophthalmol. 2021;15:551–557. doi: 10.2147/OPTH.S290404
  • Lai MM, Williams GA. Anatomical and visual outcomes of idiopathic macular hole surgery with internal limiting membrane removal using low-concentration indocyanine green. Retina. 2007;27(4):477–482. doi: 10.1097/01.iae.0000247166.11120.21
  • Elhusseiny AM, Schwartz SG, Flynn HW, et al. Long-term outcomes after macular hole surgery. Ophthalmol Retina. 2020;4(4):369–376. doi: 10.1016/j.oret.2019.09.015
  • Mansour HA, Uwaydat SH, Parodi M, et al. Recovery course of foveal microstructure in the nonsurgical resolution of full-thickness macular hole. Graefes Arch Clin Exp Ophthalmol. 2022;260(10):3173–3183. doi: 10.1007/s00417-022-05672-z
  • Yu Y, Liang X, Wang Z, et al. Internal limiting membrane peeling and air tamponade for stage iii and stage iv idiopathic macular hole. Retina. 2020;40(1):66–74. doi: 10.1097/IAE.0000000000002340
  • Fallico M, Jackson, T. L., Chronopoulos, A et al. Factors predicting normal visual acuity following anatomically successful macular hole surgery. Acta Ophthalmol. 2021;99(3):e324–e329. doi: 10.1111/aos.14575
  • Ullrich S, Haritoglou, C., Gass, C. T. et al. Macular hole size as a prognostic factor in macular hole surgery. Br J Ophthalmol. 2002;86(4):390–393. doi: 10.1136/bjo.86.4.390
  • Tayyab H, Siddiqui R, Jahangir S, et al. Optical coherence tomography based indices in predicting functional outcome of macular hole surgery: a retrospective chart review. Pak J Med Sci. 2021;37(5):1504–1508. doi: 10.12669/pjms.37.5.4126
  • Xiao Y, Hu Y, Quan W, et al. Machine learning-based prediction of anatomical outcome after idiopathic macular hole surgery. Ann Transl Med. 2021;9(10):830. doi: 10.21037/atm-20-8065
  • Yang J, Xia H, Liu Y, et al. Ellipsoid zone and external limiting membrane-related parameters on spectral domain-Optical coherence tomography and their relationships with visual prognosis after successful macular hole surgery. Front Med. 2021;8:779602. doi: 10.3389/fmed.2021.779602
  • Chatziralli IP, Theodossiadis PG, Steel DHW. Internal limiting membrane peeling in macular hole surgery; why, when, and how? Retina. 2018;38(5):870–882. doi: 10.1097/IAE.0000000000001959
  • Parravano M, Giansanti F, Eandi CM, et al. Vitrectomy for idiopathic macular hole. Cochrane Database Syst Rev. 2015;2015(5): CD009080. doi: 10.1002/14651858.CD009080.pub2
  • Chen H, Chen W, Zheng K, et al. Prediction of spontaneous closure of traumatic macular hole with spectral domain optical coherence tomography. Sci Rep. 2015;5(1):12343. doi: 10.1038/srep12343
  • Ferreira MA, Maia A, Machado AJ, et al. Human amniotic membrane for the treatment of large and refractory macular holes: a retrospective, multicentric, interventional study. Int J Retina Vitreous. 2021;7(1):38. doi: 10.1186/s40942-021-00308-6
  • de Smet MD, Valmaggia, C., Zarranz-Ventura, J. et al. Microplasmin: ex vivo characterization of its activity in porcine vitreous. Invest Ophthalmol Vis Sci. 2009;50(2):814–819. doi: 10.1167/iovs.08-2185
  • Johnson MW, Fahim AT, Rao RC. Acute ocriplasmin retinopathy. Retina. 2015;35(6):1055–1058. doi: 10.1097/IAE.0000000000000667
  • Stalmans P, Benz MS, Gandorfer A, et al. Enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes. N Engl J Med. 2012;367(7):606–615. doi: 10.1056/NEJMoa1110823
  • Jackson TL, Haller J, Blot KH, et al. Ocriplasmin for treatment of vitreomacular traction and macular hole: a systematic literature review and individual participant data meta-analysis of randomized, controlled, double-masked trials. Surv Ophthalmol. 2022;67(3):697–711. doi: 10.1016/j.survophthal.2021.08.003
  • Reiss B, Smithen L, Mansour S. Transient vision loss after ocriplasmin injection. Retina. 2015;35(6):1107–1110. doi: 10.1097/IAE.0000000000000542
  • Tibbetts MD, Reichel E, Witkin AJ. Vision loss after intravitreal ocriplasmin: correlation of spectral-domain optical coherence tomography and electroretinography. JAMA Ophthalmol. 2014;132(4):487–490. doi: 10.1001/jamaophthalmol.2013.8258
  • Mori K, Saito S, Gehlbach PL, et al. Treatment of stage 2 macular hole by intravitreous injection of expansile gas and induction of posterior vitreous detachment. Ophthalmol. 2007;114(1):127–133. doi: 10.1016/j.ophtha.2006.07.001
  • Han R, Zhang C, Zhao X, et al. Treatment of primary full-thickness macular hole by intravitreal injection of expansile gas. Eye (Lond). 2019;33(1):136–143. doi: 10.1038/s41433-018-0098-z
  • Kelly NE, Wendel RT. Vitreous surgery for idiopathic macular holes. Results of a pilot study. Arch Ophthalmol. 1991;109(5):654–659. doi: 10.1001/archopht.1991.01080050068031
  • Ezra E, Gregor ZJ, N. Morfields Macular Hole Study Ggroup Report. Surgery for idiopathic full-thickness macular hole: two-year results of a randomized clinical trial comparing natural history, vitrectomy, and vitrectomy plus autologous serum: Moorfields macular hole study group Report No. 1. Arch Ophthalmol. 2004;122(2):224–236. doi: 10.1001/archopht.122.2.224
  • Oh H. Idiopathic macular hole. Dev Ophthalmol. 2014;54:150–158.
  • Hejsek L, Stepanov A, Dusova J, et al. Microincision 25G pars plana vitrectomy with peeling of the inner limiting membrane and air tamponade in idiopathic macular hole. Eur J Ophthalmol. 2017;27(1):93–97. doi: 10.5301/ejo.5000815
  • Tezel TH, Hondur A. Covering macular hole with human amniotic membrane promotes more pronounced wound healing response compared to retinal autografts. Annual Meeting of the American Society of Retinal Specialists; July , 26-30; Chicago, IL. 2019.
  • Kwok AK, Lai TY, Wong VW. Idiopathic macular hole surgery in Chinese patients: a randomised study to compare indocyanine green-assisted internal limiting membrane peeling with no internal limiting membrane peeling. Hong Kong Med J. 2005;11(4):259–266.
  • Lois N, Burr, J., Norrie, J. et al. Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial. Invest Ophthalmol Vis Sci. 2011;52(3):1586–1592. doi: 10.1167/iovs.10-6287
  • Spiteri Cornish K, Lois N, Scott NW, et al. Vitrectomy with internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole. Ophthalmol. 2014;121(3):649–655. doi: 10.1016/j.ophtha.2013.10.020
  • Rahimy E, McCannel CA. IMPACT of INTERNAL LIMITING MEMBRANE PEELING on MACULAR HOLE REOPENING: a systematic review and meta-analysis. Retina. 2016;36(4):679–687. doi: 10.1097/IAE.0000000000000782
  • Tadayoni R, G C C, JF K. Internal limiting membrane peeling for large macular holes: a randomized multicentric and controlled clinical trial. ARVO May , 3–7; Ft. Lauderdale. 2009.
  • Rubinstein A, Bates R, Benjamin L, et al. Iatrogenic eccentric full thickness macular holes following vitrectomy with ILM peeling for idiopathic macular holes. Eye (Lond). 2005;19(12):1333–1335. doi: 10.1038/sj.eye.6701771
  • AJ P, B D, Zeng Q, et al. Internal limiting membrane peel is associated with increased ganglion cell loss and poor visual outcome in patients with primary open Angle glaucoma. Invest Ophthalmol Vis Sci. 2015;56(7):4571.
  • Dogramaci M, Williamson TH. Dynamics of epiretinal membrane removal off the retinal surface: a computer simulation project. Br J Ophthalmol. 2013;97(9):1202–1207. doi: 10.1136/bjophthalmol-2013-303598
  • Abdelkader E, Lois N. Internal limiting membrane peeling in vitreo-retinal surgery. Surv Ophthalmol. 2008;53(4):368–396. doi: 10.1016/j.survophthal.2008.04.006
  • Ohta K, Sato A, Fukui E. Asymmetrical thickness of parafoveal retina around surgically closed macular hole. Br J Ophthalmol. 2010;94(11):1545–1546. doi: 10.1136/bjo.2009.176693
  • Bae K, Kang SW, Kim JH, et al. Extent of internal limiting membrane peeling and its impact on macular hole surgery outcomes: a randomized trial. Am J Ophthalmol. 2016;169:179–188. doi: 10.1016/j.ajo.2016.06.041
  • Modi A, Giridhar A, Gopalakrishnan M. Comparative analysis of outcomes with variable diameter internal limiting membrane peeling in surgery for idiopathic macular hole repair. Retina. 2017;37(2):265–273. doi: 10.1097/IAE.0000000000001123
  • Christensen UC, Kroyer K, Sander B, et al. Value of internal limiting membrane peeling in surgery for idiopathic macular hole stage 2 and 3: a randomised clinical trial. Br J Ophthalmol. 2009;93(8):1005–1015. doi: 10.1136/bjo.2008.151266
  • Tsuiki E, Fujikawa, A., Miyamura, N. et al. Visual field defects after macular hole surgery with indocyanine green-assisted internal limiting membrane peeling. Am J Ophthalmol. 2007;143(4):704–705. doi: 10.1016/j.ajo.2006.10.051
  • Tada A, Machida, S., Hara, Y. et al. Long-term observations of thickness changes of each retinal layer following macular hole surgery. J Ophthalmol. 2021;2021:1–10. doi: 10.1155/2021/4624164
  • Al-Abdulla NA, Thompson JT, Sjaarda RN. Results of macular hole surgery with and without epiretinal dissection or internal limiting membrane removal. Ophthalmol. 2004;111(1):142–149. doi: 10.1016/j.ophtha.2003.05.005
  • Kang SW, Ahn K, Ham DI. Types of macular hole closure and their clinical implications. Br J Ophthalmol. 2003;87(8):1015–1019. doi: 10.1136/bjo.87.8.1015
  • Wilczynski T, Heinke A, Niedzielska-Krycia A, et al. Optical coherence tomography angiography features in patients with idiopathic full-thickness macular hole, before and after surgical treatment. Clin Interv Aging. 2019;14:505–514. doi: 10.2147/CIA.S189417
  • Clark A, Balducci N, Pichi F, et al. Swelling of the arcuate nerve fiber layer after internal limiting membrane peeling. Retina. 2012;32(8):1608–1613. doi: 10.1097/IAE.0b013e3182437e86
  • Tadayoni R, Paques M, Massin P, et al. Dissociated optic nerve fiber layer appearance of the fundus after idiopathic epiretinal membrane removal. Ophthalmol. 2001;108(12):2279–2283. doi: 10.1016/S0161-6420(01)00856-9
  • Runkle AP, Srivastava, S. K., Yuan, A et al. Factors associated with development of Dissociated optic nerve fiber layer appearance in the pioneer intraoperative Optical coherence tomography study. Retina. 2018;38(Suppl 1):S103–S109. doi: 10.1097/IAE.0000000000002017
  • Yamashita T, Uemura, A., Kita, H. et al. Analysis of the retinal nerve fiber layer after indocyanine green-assisted vitrectomy for idiopathic macular holes. Ophthalmol. 2006;113(2):280–284. doi: 10.1016/j.ophtha.2005.10.046
  • Tortuyaux F, Angioï, K., Conart, J. B et al. [Long-term functional and anatomical effects after macular hole surgery with internal limiting membrane peeling]. J Fr Ophtalmol. 2021;44(4):523–530. doi: 10.1016/j.jfo.2020.06.049
  • Kadonosono K, Itoh, N., Uchio, E et al. Staining of internal limiting membrane in macular hole surgery. Arch Ophthalmol. 2000;118(8):1116–1118. doi: 10.1001/archopht.118.8.1116
  • Engel E, Schraml, R., Maisch, T. et al. Light-induced decomposition of indocyanine green. Invest Ophthalmol Vis Sci. 2008;49(5):1777–1783. doi: 10.1167/iovs.07-0911
  • Gandorfer A, Haritoglou C, Gass CA, et al. Indocyanine green-assisted peeling of the internal limiting membrane may cause retinal damage. Am J Ophthalmol. 2001;132(3):431–433. doi: 10.1016/S0002-9394(01)01087-X
  • Burk SE, Da Mata, A. P., Snyder, M. E. et al. Indocyanine green-assisted peeling of the retinal internal limiting membrane. Ophthalmol. 2000;107(11):2010–2014. doi: 10.1016/S0161-6420(00)00375-4
  • Gass CA, Haritoglou C, Schaumberger M, et al. Functional outcome of macular hole surgery with and without indocyanine green-assisted peeling of the internal limiting membrane. Graefes Arch Clin Exp Ophthalmol. 2003;241(9):716–720. doi: 10.1007/s00417-003-0710-0
  • Kanda S, Uemura, A., Yamashita, T. et al. Visual field defects after intravitreous administration of indocyanine green in macular hole surgery. Arch Ophthalmol. 2004;122(10):1447–1451. doi: 10.1001/archopht.122.10.1447
  • Sippy BD, Engelbrecht NE, Hubbard GB, et al. Indocyanine green effect on cultured human retinal pigment epithelial cells: implication for macular hole surgery. Am J Ophthalmol. 2001;132(3):433–435. doi: 10.1016/S0002-9394(01)01061-3
  • Gandorfer A, Haritoglou, C., Gandorfer, A. et al. Retinal damage from indocyanine green in experimental macular surgery. Invest Ophthalmol Vis Sci. 2003;44(1):316–323. doi: 10.1167/iovs.02-0545
  • Patoni Popescu IS, Mușat O, Stanca S, et al. Vital dyes in macular hole surgery. Exp Ther Med. 2021;21(5):527. doi: 10.3892/etm.2021.9959
  • Abdelkader EA, McBain VA, ANAND M, et al. In vivo safety of trypan blue use in vitreoretinal surgery. Retina. 2011;31(6):1122–1127. doi: 10.1097/IAE.0b013e3182003adb
  • Jain S, Kishore K, Sharma YR. Progressive atrophy of retinal pigment epithelium after trypan-blue-assisted ILM peeling for macular hole surgery. Indian J Ophthalmol. 2013;61(5):235–237. doi: 10.4103/0301-4738.111180
  • Shukla D, Kalliath J, Neelakantan N, et al. A comparison of brilliant blue G, trypan blue, and indocyanine green dyes to assist internal limiting membrane peeling during macular hole surgery. Retina. 2011;31(10):2021–2025. doi: 10.1097/IAE.0b013e318213618c
  • Michalewska Z, Michalewski, J., Adelman, R. A. et al. Inverted internal limiting membrane flap technique for large macular holes. Ophthalmol. 2010;117(10):2018–2025. doi: 10.1016/j.ophtha.2010.02.011
  • Yuan J, Zhang, L. L., Lu, Y. J., et al. Vitrectomy with internal limiting membrane peeling versus inverted internal limiting membrane flap technique for macular hole-induced retinal detachment: a systematic review of literature and meta-analysis. BMC Ophthalmol. 2017;17(1):219. doi: 10.1186/s12886-017-0619-8
  • Marques RE, Sousa DC, Leal I, et al. Complete ILM peeling versus inverted flap technique for macular hole surgery: a meta-analysis. Ophthalmic Surg Lasers Imaging Retina. 2020;51(3):187–A2. doi: 10.3928/23258160-20200228-08
  • Shin MK, Park, K. H., Park, S. W. et al. Perfluoro-n-octane-assisted single-layered inverted internal limiting membrane flap technique for macular hole surgery. Retina. 2014;34(9):1905–1910. doi: 10.1097/IAE.0000000000000339
  • Stopa M, Ciesielski M, Rakowicz P. Macular hole closure without endotamponade application. Retina. 2023;43(4):688–691. doi: 10.1097/IAE.0000000000002850
  • Chen SN. Large semicircular inverted internal limiting membrane flap in the treatment of macular hole in high myopia. Graefes Arch Clin Exp Ophthalmol. 2017;255(12):2337–2345. doi: 10.1007/s00417-017-3808-5
  • Aurora A, Seth A, Sanduja N. Cabbage leaf inverted flap ILM peeling for macular hole: a novel technique. Ophthalmic Surg Lasers Imaging Retina. 2017;48(10):830–832. doi: 10.3928/23258160-20170928-08
  • Gekka T, Watanabe A, Ohkuma Y, et al. Pedicle Internal Limiting Membrane Transposition Flap Technique for Refractory Macular Hole. Ophthalmic Surg Lasers Imaging Retina. 2015;46(10):1045–1046. doi: 10.3928/23258160-20151027-10
  • Morizane Y, Shiraga, F., Kimura, S. et al. Autologous transplantation of the internal limiting membrane for refractory macular holes. Am J Ophthalmol. 2014;157(4):861–869 e1. doi: 10.1016/j.ajo.2013.12.028
  • Chen SN, Hsieh YT, Yang CM. Multiple free internal limiting membrane flap insertion in the treatment of macular hole-associated retinal detachment in high myopia. Ophthalmologica. 2018;240(3):143–149. doi: 10.1159/000487337
  • Caporossi T, Carlà MM, Gambini G, et al. Spotlight on the Internal Limiting Membrane Technique for Macular Holes. Current Perspectives. Clin Ophthalmol. 2022;16:1069–1084. doi: 10.2147/OPTH.S284620
  • Almeida DRP, Chin, E. K., Tarantola, R. M et al. Effect of internal limiting membrane abrasion on retinal tissues in macular holes. Invest Ophthalmol Vis Sci. 2015;56(5):2783–2789. doi: 10.1167/iovs.14-16355
  • Mahajan VB, Chin, E. K., Tarantola, R. M. et al. Macular Hole Closure With Internal Limiting Membrane Abrasion Technique. JAMA Ophthalmol. 2015;133(6):635–641. doi: 10.1001/jamaophthalmol.2015.204
  • Chakraborty D, Sengupta S, Mukherjee A, et al. Anatomical and functional outcomes one year after vitrectomy and retinal massage for large macular holes. Indian J Ophthalmol. 2021;69(4):895–899. doi: 10.4103/ijo.IJO_1680_20
  • Charles S, Randolph JC, Neekhra A, et al. Arcuate retinotomy for the repair of large macular holes. Ophthalmic Surg Lasers Imaging Retina. 2013;44(1):69–72. doi: 10.3928/23258160-20121221-15
  • Knight D, Yu JJ, Adrean SD. Relaxing nasal retinotomy technique for closure of a macular hole that reopened after primary vitrectomy. Retin Cases Brief Rep. 2021;15(5):611–614. doi: 10.1097/ICB.0000000000000862
  • Felfeli T, Mandelcorn ED. MACULAR HOLE HYDRODISSECTION: surgical technique for the treatment of persistent, chronic, and large macular holes. Retina. 2019;39(4):743–752. doi: 10.1097/IAE.0000000000002013
  • Lam D, Srour M, Semoun O, et al. Resolution of a macular hole complicating a pseudophakic macular edema with nonsurgical treatment. RETINAL Cases & Brief Reports. 2018;12(2):131–135. doi: 10.1097/ICB.0000000000000446
  • Uwaydat SH, Mansour A, Ascaso FJ, et al. Clinical characteristics of full thickness macular holes that closed without surgery. Br J Ophthalmol. 2022;106(10):1463–1468. doi: 10.1136/bjophthalmol-2021-319001
  • Niffenegger JH, Fong DS, Wong KL, et al. Treatment of secondary full-thickness macular holes with Topical therapy. Ophthalmol Retina. 2020;4(7):695–699. doi: 10.1016/j.oret.2020.01.014
  • Marques RE, Sousa DC. Macular Hole Closure with Topical Carbonic Anhydrase Inhibitor. Ophthalmol Retina. 2019;3(4):304. doi: 10.1016/j.oret.2019.01.002
  • Feria Anzaldo E, El Hamichi, S., Gold, A. et al. Case series: small full-thickness macular hole treated with Topical dorzolamide and bevacizumab intravitreal injections. Optom Vis Sci. 2021;98(12):1408–1412. doi: 10.1097/OPX.0000000000001820
  • Cho HY, Kim YT, Kang SW. Laser photocoagulation as adjuvant therapy to surgery for large macular holes. Korean J Ophthalmol. 2006;20(2):93–98. doi: 10.3341/kjo.2006.20.2.93
  • Olsen TW, STERNBERG P, CAPONE A, et al. Macular hole surgery using thrombin-activated fibrinogen and selective removal of the internal limiting membrane. Retina. 1998;18(4):322–329. doi: 10.1097/00006982-199808000-00005
  • Thompson JT, Smiddy WE, Williams GA, et al. Comparison of recombinant transforming growth factor-beta-2 and placebo as an adjunctive agent for macular hole surgery. Ophthalmol. 1998;105(4):700–706. doi: 10.1016/S0161-6420(98)94027-1
  • Marchetti E, Mancini L, Bernardi S, et al. Evaluation of different autologous platelet concentrate biomaterials: morphological and biological comparisons and considerations. Materials. 2020;13(10):2282. doi: 10.3390/ma13102282
  • Prakash S, Thakur A. Platelet concentrates: past, present and future. J Maxillofac Oral Surg. 2011;10(1):45–49. doi: 10.1007/s12663-011-0182-4
  • Dimopoulos S, William A, Voykov B, et al. Anatomical and visual outcomes of autologous thrombocyte serum concentrate in the treatment of persistent full-thickness idiopathic macular hole after ILM peeling with brilliant blue G and membrane blue dual. Acta Ophthalmol. 2017;95(5):e429–e430. doi: 10.1111/aos.12971
  • Lai CC, Chen Y-P, Wang N-K, et al. Vitrectomy with internal limiting membrane repositioning and autologous blood for macular hole retinal detachment in highly myopic eyes. Ophthalmol. 2015;122(9):1889–1898. doi: 10.1016/j.ophtha.2015.05.040
  • Chen SN, Yang CM. Lens Capsular flap transplantation in the management of refractory macular hole from multiple etiologies. Retina. 2016;36(1):163–170. doi: 10.1097/IAE.0000000000000674
  • Peng J, Chen C, Zhang H, et al. Long-term surgical outcomes of lens Capsular flap transplantation in the management of refractory macular hole. Retina. 2021;41(4):726–734. doi: 10.1097/IAE.0000000000002922
  • Cisiecki S, Boninska K, Bednarski M. Autologous Lens Capsule Flap Transplantation for Persistent Macular Holes. J Ophthalmol. 2021;2021:1–5. doi: 10.1155/2021/8148792
  • Grewal DS, Mahmoud TH. Autologous neurosensory retinal free flap for closure of refractory myopic macular holes. JAMA Ophthalmol. 2016;134(2):229–230. doi: 10.1001/jamaophthalmol.2015.5237
  • Li Y, Li, Z., Xu, C et al. Autologous neurosensory retinal transplantation for recurrent macular hole retinal detachment in highly myopic eyes. Acta Ophthalmol. 2020;98(8):e983–e990. doi: 10.1111/aos.14442
  • Patel SN, Mahmoud, T. H., Kazahaya, M et al. Autologous neurosensory retinal transplantation: bridging the gap. Retina. 2021;41(12):2417–2423. doi: 10.1097/IAE.0000000000003210
  • Tanaka S, Inoue M, Inoue T, et al. Autologous retinal transplantation as a primary treatment for large chronic macular holes. Retina. 2020;40(10):1938–1945. doi: 10.1097/IAE.0000000000002693
  • Lumi X, Petrovic Pajic, S., Sustar, M. et al. Autologous neurosensory free-flap retinal transplantation for refractory chronic macular hole-outcomes evaluated by OCT, microperimetry, and multifocal electroretinography. Graefes Arch Clin Exp Ophthalmol. 2021;259(6):1443–1453. doi: 10.1007/s00417-020-04981-5
  • Rizzo S, Caporossi, T., Tartaro, R. et al. A Human Amniotic Membrane Plug to Promote Retinal Breaks Repair and Recurrent Macular Hole Closure. Retina. 2019;39(Suppl 1):S95–S103. doi: 10.1097/IAE.0000000000002320
  • Caporossi T, Governatori, L., Verdina, T. et al. Human amniotic membrane for failed macular hole. A case of initial unsuccessful outcome that resolved after amniotic membrane exchange. Eur J Ophthalmol. 2021;32(2):NP1–NP5. doi: 10.1177/11206721211058996
  • Mamede AC, Carvalho MJ, Abrantes AM, et al. Amniotic membrane: from structure and functions to clinical applications. cell tissue Res. Cell Tissue Res. 2012;349(2):447–458. doi: 10.1007/s00441-012-1424-6
  • Pacini B, Bacherini, D., Savastano, A et al. Comparative analysis of macular microstructure in eyes treated with human amniotic membrane plug or internal limiting membrane transplant for failed macular hole. Acta Ophthalmol. 2022;100(4):e1031–e1035. doi: 10.1111/aos.15013
  • Caporossi T, Pacini B, Bacherini D, et al. Human amniotic membrane plug to promote failed macular hole closure. Sci Rep. 2020;10(1):18264. doi: 10.1038/s41598-020-75292-2
  • Saad SM, Rizvi SF, Tufail Khan MA, et al. Outcome Of Recurrent Macular Hole Closure With Amniotic Membrane Plug. J Ayub Med Coll Abbottabad. 2021;33(2):179–182.
  • Berger JW, Brucker AJ. The magnitude of the bubble buoyant pressure: implications for macular hole surgery. Retina. 1998;18(1):84–86. author reply 86-8. doi: 10.1097/00006982-199818010-00020
  • Bainbridge J, Herbert E, Gregor Z. Macular holes: vitreoretinal relationships and surgical approaches. Eye (Lond). 2008;22(10):1301–1309. doi: 10.1038/eye.2008.23
  • Thompson JT, Glaser, B. M., Sjaarda, R. N et al. Effects of intraocular bubble duration in the treatment of macular holes by vitrectomy and transforming growth factor-beta 2. Ophthalmol. 1994;101(7):1195–1200. doi: 10.1016/S0161-6420(94)31187-0
  • Casini G, Loiudice P, De Cillà S, et al. Sulfur hexafluoride (SF(6)) versus perfluoropropane (C(3)F(8)) tamponade and short term face-down position for macular hole repair: a randomized prospective study. Int J Retina Vitreous. 2016;2(1):10. doi: 10.1186/s40942-016-0036-9
  • Thompson JT, SMIDDY WE, GLASER BM, et al. Intraocular tamponade duration and success of macular hole surgery. Retina. 1996;16(5):373–382. doi: 10.1097/00006982-199616050-00002
  • Goldbaum MH, McCuen BW, Hanneken AM, et al. Silicone oil tamponade to seal macular holes without position restrictions. Ophthalmol. 1998;105(11):2140–2147. discussion 2147-8. doi: 10.1016/S0161-6420(98)91140-X
  • Pichi F, Hay S, Abboud EB. Inner retinal toxicity due to silicone oil: a case series and review of the literature. Int Ophthalmol. 2020;40(9):2413–2422. doi: 10.1007/s10792-020-01418-0
  • Kurt RA, Kapran Z. Heavy silicone oil as an Endotamponade in recurrent or complicated retinal detachment and macular hole. Turk J Ophthalmol. 2022;52(2):119–124. doi: 10.4274/tjo.galenos.2021.83648
  • Mulhern MG, Cullinane A, Cleary PE. Visual and anatomical success with short-term macular tamponade and autologous platelet concentrate. Graefes Arch Clin Exp Ophthalmol. 2000;238(7):577–583. doi: 10.1007/s004170000154
  • Yamashita T, Sakamoto T, Yamashita T, et al. INDIVIDUALIZED, SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY–GUIDED FACEDOWN POSTURING AFTER MACULAR HOLE SURGERY. Retina. 2014;34(7):1367–1375. doi: 10.1097/IAE.0000000000000087
  • Xia S, Zhao X, Wang E, et al. Comparison of face-down posturing with nonsupine posturing after macular hole surgery: a meta-analysis. BMC Ophthalmol. 2019;19(1):34. doi: 10.1186/s12886-019-1047-8
  • Tsai HR, Chen T-L, Chang C-Y, et al. Face-down posture versus non-face-down posture following large idiopathic macular hole surgery: a systemic review and meta-analysis. J Clin Med. 2021;10(21):4895. doi: 10.3390/jcm10214895
  • Kuhn F, Morris R, Mester V, et al. Internal limiting membrane removal for traumatic macular holes. Ophthalmic Surg Lasers Imaging. 2001;32(4):308–315. doi: 10.3928/1542-8877-20010701-09
  • Tafoya ME, Lambert HM, Vu L, et al. Visual outcomes of silicone oil versus gas tamponade for macular hole surgery. Semin Ophthalmol. 2003;18(3):127–131. doi: 10.1076/soph.18.3.127.29808
  • Kunikata H, Osada U, Abe T, et al. Efficacy of early microincision vitrectomy surgery in traumatic macular hole. Graefes Arch Clin Exp Ophthalmol. 2021;259(8):2451–2454. doi: 10.1007/s00417-021-05139-7
  • Azevedo S, Ferreira N, Meireles A. Management of pediatric traumatic macular holes - case report. Case Rep Ophthalmol. 2013;4(2):20–27. doi: 10.1159/000350543
  • Budoff G, Bhagat N, Zarbin MA. Traumatic Macular Hole: Diagnosis, Natural History, and Management. J Ophthalmol. 2019;2019:1–7. doi: 10.1155/2019/5837832
  • Wu WC, Drenser KA, Trese MT, et al. Pediatric traumatic macular hole: results of autologous plasmin enzyme-assisted vitrectomy. Am J Ophthalmol. 2007;144(5):668–672. doi: 10.1016/j.ajo.2007.07.027
  • Margherio AR, Margherio RR, Hartzer M, et al. Plasmin enzyme-assisted vitrectomy in traumatic pediatric macular holes. Ophthalmol. 1998;105(9):1617–1620. doi: 10.1016/S0161-6420(98)99027-3
  • Wang X, Zhang T, Jiang R, et al. Vitrectomy for laser-induced full-thickness macular hole. BMC Ophthalmol. 2021;21(1):135. doi: 10.1186/s12886-021-01893-8
  • Lim LS, Tsai A, Wong D, et al. Prognostic factor analysis of vitrectomy for retinal detachment associated with myopic macular holes. Ophthalmol. 2014;121(1):305–310. doi: 10.1016/j.ophtha.2013.08.033
  • Kono T, Takesue Y, Shiga S. Scleral resection technique combined with vitrectomy for a macular hole retinal detachment in highly myopic eyes. Ophthalmologica. 2006;220(3):159–163. doi: 10.1159/000091758
  • Sonmez K, Keles A. Macular Buckling surgery for retinal detachment associated with macular hole in high myopia Eye. Turk J Ophthalmol. 2017;47(6):351–354. doi: 10.4274/tjo.55453
  • Fujikawa M, Kawamura H, Kakinoki M, et al. Scleral imbrication combined with vitrectomy and gas tamponade for refractory macular hole retinal detachment associated with high myopia. Retina. 2014;34(12):2451–2457. doi: 10.1097/IAE.0000000000000246
  • Morimoto E, Shimada Y, Sugimoto M, et al. Adherence to face-down and non-supine positioning after macular hole surgery. BMC Ophthalmol. 2018;18(1):322. doi: 10.1186/s12886-018-0979-8
  • Maguire MJ, Steel DH, Yorston D, et al. Outcome of revision procedures for failed primary macular hole surgery. Retina. 2021;41(7):1389–1395. doi: 10.1097/IAE.0000000000003072
  • Szurman P, Wakili P, Stanzel BV, et al. Persistent macular holes — what is the best strategy for revision? Arch Clin Exp Ophthalmol. 2021;259(7):1781–1790. doi: 10.1007/s00417-021-05252-7
  • Schaub F, Gözlügöl N, von Goscinski C, et al. Outcome of autologous platelet concentrate and gas tamponade compared to heavy silicone oil tamponade in persistent macular hole surgery. Eur J Ophthalmol. 2021;31(2):664–672. doi: 10.1177/1120672120903704
  • Saeed MU, Heimann H, Wong D, et al. Heavy silicone oil tamponade after failed macular hole surgery with perfluoropropane (C3F8): a report of five cases. Graefes Arch Clin Exp Ophthalmol. 2009;247(5):707–709. doi: 10.1007/s00417-008-0965-6
  • Rizzo S, BELTING C, GENOVESI-EBERT F, et al. Successful treatment of persistent macular holes using “heavy silicone oil” as intraocular tamponade. Retina. 2006;26(8):905–908. doi: 10.1097/01.iae.0000250006.76155.3d
  • Li JQ, Brinken R, Holz FG, et al. Silicone oil tamponade for persistent macular holes. Eye (Lond). 2021;35(8):2206–2212. doi: 10.1038/s41433-020-01228-9
  • Li Y, Shi L, Qin H, et al. Factors associated with anatomic failure and hole reopening after macular hole surgery. J Ophthalmol. 2021;2021:1–11. doi: 10.1155/2021/7861180
  • Scott IU, Flynn HW, Smiddy WE, et al. Clinical features and outcomes of pars plana vitrectomy in patients with retained lens fragments. Ophthalmol. 2003;110(8):1567–1572. doi: 10.1016/S0161-6420(03)00488-3
  • Grajewski L, Grajewski O, Carstens J, et al. Incidence of retinal detachment after macular surgery. Klin Monbl Augenheilkd. 2021;238(5):580–583. doi: 10.1055/a-1353-5436
  • Rizzo S, Belting C, Genovesi-Ebert F, et al. Incidence of retinal detachment after small-incision, sutureless pars plana vitrectomy compared with conventional 20-gauge vitrectomy in macular hole and epiretinal membrane surgery. Retina. 2010;30(7):1065–1071. doi: 10.1097/IAE.0b013e3181cd48b0
  • Guillaubey A, Malvitte L, Lafontaine PO, et al. Incidence of retinal detachment after macular surgery: a retrospective study of 634 cases. Br J Ophthalmol. 2007;91(10):1327–1330. doi: 10.1136/bjo.2007.115162
  • Valentin-Rodriguez C, Tezel TH, Ivanisevic A. Surface modification of vitreoretinal surgical instruments with layer-by-layer films. Scanning. 2011;33(6):397–401. doi: 10.1002/sca.20240
  • Carrasco-Zevallos OM, Keller B, Viehland C, et al. Optical coherence tomography for retinal surgery: perioperative analysis to real-time four-dimensional image-guided surgery. Invest Ophthalmol Vis Sci. 2016;57(9):OCT37–50. doi: 10.1167/iovs.16-19277

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