The Institute for Healthcare Improvement ventilator bundle: definitions, summary, and brief review of the evidence

References

• www.ihi.org/IHI/Topics/Improvement/ImprovementMethods/ImprovementStories/BundleUpforSafety.htm.
   Google Scholar
• www.ihi.org/IHI/Topics/CriticalCare/Sepsis/Tools/SevereSepsisBundle.htm.
   Google Scholar
• www.ihi.org/IHI/Topics/Improvement/ImprovementMethods/Tools/VentilatorBundle.htm.
   Google Scholar
• Fernandez-Crehuet R, Diaz-Monila C, De Irala J, Martinex-Cohcha D, Salcedo-Leal I, Masa-Calles J. Nosocomial infection in an intensive-care unit: identification of risk factors. Infect Control Hosp Epidemiol 1997; 18: 825–30
   PubMed Web of Science ®Google Scholar
• Kollef MH. Ventilator-associated pneumonia: a multivariate analysis. JAMA 1993; 270: 1965–70
   PubMed Web of Science ®Google Scholar
• Drakulovic MB, Torres A, Bauer TT, Nicolas JM, Nogue S, Ferrer M, et al. Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet 1999; 354: 1851–8
   PubMed Web of Science ®Google Scholar
• Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, Sherman G, et al. The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation. Chest 1998; 114: 541–8
   PubMed Web of Science ®Google Scholar
• Kollef MH. Prevention of hospital-associated pneumonia and ventilator-associated pneumonia. Crit Care Med 2004; 32: 1396–405
   PubMed Web of Science ®Google Scholar
• Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000; 342: 1471–7
   PubMed Web of Science ®Google Scholar
• Schweickert WD, Gehlback BK, Pohlman AS, Hall JB, Kress JP, et al. Daily interruption of sedative infusions and complications of critical illness in mechanically ventilated patients. Crit Care Med 2004; 32: 1272–6
   PubMed Web of Science ®Google Scholar
• Ely EW, Baker AM, Dunagan DP, Burke HL, Smith AC, Kelly PT, et al. Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 1996; 335: 1864–9
   PubMed Web of Science ®Google Scholar
• Esteban A, Frutos F, Tobin MJ, Alia I, Solsona JF, Valverdu I, et al. A comparison of four methods of weaning patients from mechanical ventilation. N Engl J Med 1995; 332: 345–50
   PubMed Web of Science ®Google Scholar
• American Society of Health-System Pharmacists. ASHP therapeutic guidelines on stress ulcer prophylaxis. Am J Health Syst Pharm 1999;56:341–79.
   Google Scholar
• Cook DJ, Reeve BK, Guyatt GH, Heyland DK, Griffith LE, Buckingham L, et al. Stress ulcer prophylaxis in critically ill patients—resolving discordant meta-analyses. JAMA 1996; 275: 308–14
   PubMed Web of Science ®Google Scholar
• Lacroix J, Infante-Rivarde C, Jenicek M, Gauthier M, et al. Prophylaxis of upper gastrointestinal bleeding in intensive care units: a meta-analysis. Crit Care Med 1989; 17: 862–9
   PubMed Web of Science ®Google Scholar
• Tryba M. Sucralfate versus antacids or H2-antagonists for stress ulcer prophylaxis: a meta-analysis on efficacy and pneumonia rate. Crit Care Med 1991; 19: 942–9
   PubMed Web of Science ®Google Scholar
• Cook DJ, Fuller HD, Guyatt GH, Marshall JC, Lessa D, Hall R, et al. Risk factors for gastrointestinal bleeding in critically ill patients. N Engl J Med 1994; 330: 377–81
   PubMed Web of Science ®Google Scholar
• Geerts WH, Pineo GF, Heit JA, Bergqvist D, Lessen MR, Colwell CW, et al. Prevention of venous thromboembolism—the seventh ACCP conference on antithrombotic and thromobolytic therapy. Chest 2004; 126: 338S–400S
   PubMedGoogle Scholar
• Cade JF. High risk of the critically ill for venous thromboembolism. Crit Care Med 1982; 10: 448–50
   PubMed Web of Science ®Google Scholar
• Fraisse F, Holzapfel L, Couland JM, Simonneau G, Bedock B, Feissel M, et al. Nadroparin in the prevention of deep vein thrombosis in acute decompensated COPD. Am J Respir Crit Care Med 2000; 161: 1109–14
   PubMed Web of Science ®Google Scholar
• Geerts WH, Heit JA, Clagett GP, Pineo GF, Colwell CW, Anderson FA, et al. Prevention of venous thromboembolism. Chest 2001; 119: 132S–75S
   PubMed Web of Science ®Google Scholar
• Hull RD, Raskob GE, Gent M, McLoughlin D, Julian D, Smith FC, et al. Effectiveness of intermittent pneumatic leg compression for preventing deep vein thrombosis after total hip replacement. JAMA 1990; 263: 2313–7
   PubMed Web of Science ®Google Scholar
• Wille-Jorgensen P. Prophylaxis of postoperative thromboembolism with a combination of heparin and graduated compression stockings. Int Angiol 1996; 15(Suppl): 15–20
   Google Scholar
• Nurmohamed MT, Rosendaal FR, Buller HR, Dekkar E, Hommes DW, Vandenbroucke JP, et al. Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis. Lancet 1992; 340: 152–6
   PubMed Web of Science ®Google Scholar
• Pulmonary Embolism Prevention (PEP) Trial Collaborative Group. Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) Trial. Lancet 2000;355:1295–302.
   PubMed Web of Science ®Google Scholar
• Powers PJ, Gent M, Jay RM, Julian DH, Turpie AG, Levine M, et al. A randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of venous thromboembolism after surgery for fractured hip. Arch Intern Med 1989; 149: 771–4
   PubMed Web of Science ®Google Scholar