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Editorial

Is next-generation sequencing the future of measurable residual disease assays for Philadelphia chromosome-positive acute lymphoblastic leukemia?

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Pages 189-191 | Received 09 Feb 2024, Accepted 09 May 2024, Published online: 14 May 2024

References

  • Jabbour E, Short NJ, Ravandi F, et al. Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study. Lancet Haematol. 2018 Dec;5(12):e618–e627. doi: 10.1016/S2352-3026(18)30176-5
  • Jabbour E, Short NJ, Jain N, et al. Ponatinib and blinatumomab for Philadelphia chromosome-positive acute lymphoblastic leukaemia: a US, single-centre, single-arm, phase 2 trial. Lancet Haematol. 2023 Jan;10(1):e24–e34. doi: 10.1016/S2352-3026(22)00319-2
  • Foà R, Bassan R, Elia L, et al. Long-term results of the dasatinib-blinatumomab protocol for adult Philadelphia-positive ALL. J Clin Oncol. 2024 Mar 10;42(8);881–885. doi: 10.1200/JCO.23.01075
  • Short NJ, Jabbour E, Albitar M, et al. Recommendations for the assessment and management of measurable residual disease in adults with acute lymphoblastic leukemia: a consensus of North American experts. Am J Hematol. 2019 Feb;94(2):257–265. doi: 10.1002/ajh.25338
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  • Cazzaniga G, De Lorenzo P, Alten J, et al. Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies. Haematologica. 2018 Jan;103(1):107–115. doi: 10.3324/haematol.2017.176917
  • Hovorkova L, Zaliova M, Venn NC, et al. Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology. Blood. 2017 May 18;129(20):2771–2781. doi: 10.1182/blood-2016-11-749978
  • Zuna J, Hovorkova L, Krotka J, et al. Minimal residual disease in BCR: ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease. Leukemia. 2022 Dec;36(12):2793–2801. doi: 10.1038/s41375-022-01668-0
  • Short NJ, Jabbour E, Macaron W, et al. Ultrasensitive NGS MRD assessment in Ph+ ALL: prognostic impact and correlation with RT-PCR for BCR: ABL1. Am J Hematol. 2023 Aug;98(8):1196–1203. doi: 10.1002/ajh.26949
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  • Short NJ, Kantarjian H, Ravandi F, et al. High-sensitivity next-generation sequencing MRD assessment in ALL identifies patients at very low risk of relapse. Blood Adv. 2022 Jul 12;6(13):4006–4014. doi: 10.1182/bloodadvances.2022007378
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