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Review

Restoring gut physiology in short bowel patients: from bench to clinical application of autologous intestinal reconstructive procedures

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Pages 785-796 | Received 10 Mar 2019, Accepted 02 Jul 2019, Published online: 15 Jul 2019

References

  • Khalil BA, Ba’ath ME, Aziz A, et al. Intestinal rehabilitation and bowel reconstructive surgery: improved outcomes in children with short bowel syndrome. J Pediatr Gastroenterol Nutr. 2012;54:505–509.
  • Goulet O, Ricour C. The short bowel syndrome. In: Buts JP, Sokal E, editors. Management of digestive and liver disorders in infants and children. UK: Elsevier Science Publishers; 1993. p. 307–318.
  • Buchman AL. Intestinal failure and rehabilitation. Gastroenterol Clin North Am. 2018;47:327–340.
  • Duggan CP, Jaksic T. Pediatric intestinal failure. N Engl J Med. 2017;377:666–675.
  • Grainger JT, Maeda Y, Donnelly SC, et al. Assessment and management of patients with intestinal failure: a multidisciplinary approach. Clin Exp Gastroenterol. 2018;11:233–241.
  • Costa G, Parekh N, Osman M, et al. Composite and multivisceral transplantation: nomenclature, surgical techniques, current practice, and long-term outcome. Surg Clin North Am. 2019;99:129–151.
  • Almond SL, Haveliwala Z, Khalil B, et al. Autologous intestinal reconstructive surgery to reduce bowel dilatation improves intestinal adaptation in children with short bowel syndrome. J Pediatr Gastroenterol Nutr. 2013;56:631–634.
  • Carey S, Kalachov M, Jones L, et al. Development of consensus on models of care in adults with intestinal failure using a modified Delphi approach. J Gastroenterol Hepatol. 2018 Feb 27. Epub ahead of print.
  • Neelis E, de Koning B, van Winckel M, et al. Wide variation in organisation and clinical practice of paediatric intestinal failure teams: an international survey. Clin Nutr. 2018;37:2271–2279.
  • Javid PJ, Wendel D, Horslen SP. Organization and outcomes of multidisciplinary intestinal failure teams. Semin Pediatr Surg. 2018;27:218–222.
  • Hollwarth ME. Short bowel syndrome: pathophysiological and clinical aspects. Pathophysiology. 1999;6:1–19.
  • Struijs MC, Diamond IR, de Silva N, et al. Establishing norms for intestinal length in children. J Pediatr Surg. 2009;44:933–938.
  • Weaver LT, Austin S, Cole TJ. Small intestinal length: a factor essential for gut adaptation. Gut. 1991;32:1321–1323.
  • Pironi L. Definitions of intestinal failure and the short bowel syndrome. Best Pract Res Clin Gastroenterol. 2016;30:173–185.
  • Rege A. The surgical approach to short bowel syndrome - Autologous reconstruction versus transplantation. Viszeralmedizin. 2014;30:179–189.
  • Merras-Salmio L, Mutanen A, Ylinen E, et al. Pediatric intestinal failure: the key outcomes for the first 100 patients treated in a National Tertiary Referral Center during 1984–2017. JPEN J Parenter Enteral Nutr. 2018;42:1304–1313.
  • Totonelli G, Tambucci R, Boscarelli A, et al. Pediatric intestinal rehabilitation and transplantation registry: initial report from a european collaborative registry. Eur J Pediatr Surg. 2018;28:75–80.
  • Duro D, Kalish LA, Johnston P, et al. Risk factors for intestinal failure in infants with necrotizing enterocolitis: a glaser pediatric research network study. J Pediatr. 2010;157:203–208.
  • Sjoberg Bexelius T, Ahle M, Elfvin A, et al. Intestinal failure after necrotising enterocolitis: incidence and risk factors in a Swedish population-based longitudinal study. BMJ Paediatr Open. 2018;2:e000316.
  • Cohran V. Intestinal failure: the long and short of the matter. J Pediatr. 2015;167:6–8.
  • Pederiva F, Sgrò A, Coletta R, et al. Outcomes in patients with short bowel syndrome after autologous intestinal reconstruction: does etiology matter? J Pediatr Surg. 2018;53:1345–1350.
  • Kimura K, Soper RT. A new bowel elongation technique for the short-bowel syndrome using the isolated bowel segment Iowa models. J Pediatr Surg. 1993;28:792–794.
  • Bianchi A. Intestinal lengthening: a technique for increasing small intestinal length. J Pediatr Surg. 1980;15:145–151.
  • Bianchi A. Longitudinal Intestinal Lengthening and tailoring: results in 20 children. J R Soc Med. 1987;90:429–433.
  • King B, Carlson G, BA K, et al. Intestinal bowel lengthening in children with short bowel syndrome: systematic review of the Bianchi and STEP procedures. World J Surg. 2013;37:694–704.
  • Brown CR, DiBaise JK. Intestinal rehabilitation: a management program for short-bowel syndrome. Prog Transplant. 2004;14:290–296.
  • Merritt RJ, Cohran V, Raphael BP. Intestinal rehabilitation programs in the management of pediatric intestinal failure and short bowel syndrome. JPGN. 2017;65:588–596.
  • Kim HB, Fauza D, Garza J, et al. Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure. J Pediatr Surg. 2003;38:425–429.
  • Suri M, Dicken B, PN N, et al. The next step? Use of tissue fusion technology to perform the serial transverse enteroplasty–proof of principle. J Pediatr Surg. 2012;47:938–943.
  • Chang RW, Javid PJ, Oh JT, et al. Serial transverse enteroplasty enhances intestinal function in a model of short bowel syndrome. Ann Surg. 2006;243:223–228.
  • Kaji T, Tanaka H, Wallace LE, et al. Nutritional effects of the serial transverse enteroplasty procedure in experimental short bowel syndrome. J Pediatr Surg. 2009;44:1552–1559.
  • Modi BP, Ching YA, Langer M, et al. Preservation of intestinal motility after the serial transverse enteroplasty procedure in a large animal model of short bowel syndrome. J Pediatr Surg. 2009;44:229–235. discussion 235.
  • Piper H, Modi BP, Kim HB, et al. The second STEP: the feasibility of repeat serial transverse enteroplasty. J Pediatr Surg. 2006;41:1951–1956.
  • Mutanen A, Barrett M, Feng Y, et al. Short bowel mucosal morphology, proliferation and inflammation at first and repeat STEP procedures. J Gastrointest Surg. 2019;23:331-338.
  • Frongia G, Majlesara A, Saffari A, et al. Simultaneous Serial Transverse Enteroplasty (STEP) in size mismatch small bowel transplantations. J Gastrointest Surg. 2019;23:331-338.
  • Kim HB, Lee PW, Garza J, et al. Serial transverse enteroplasty for short bowel syndrome: a case report. J Pediatr Surg. 2003;38:881–885.
  • Javid PJ, Kim HB, Duggan CP, et al. Serial transverse enteroplasty is associated with successful short-term outcomes in infants with short bowel syndrome. J Pediatr Surg. 2005;40:1019–1023. discussion 1023–1024.
  • Belza C, Fitzgerald K, de Silva N, et al. Predicting intestinal adaptation in pediatric intestinal failure: a retrospective cohort study. Ann Surg. 2019;269:988-993.
  • Tannuri U. Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure, and serial transverse enteroplasty for short bowel syndrome. J Pediatr Surg. 2003;38:1845. author reply 1845–1846.
  • Sheth NP. Serial transverse enteroplasty. J Pediatr Surg. 2005;40:1060. author reply 1060.
  • Sheth N. Serial transverse enteroplasty is associated with successful short-term outcomes in infants with short bowel syndrome. J Pediatr Surg. 2005;40:1972.
  • Lilja HE, Finkel Y, Wester T. Serial transverse enteroplasty (STEP). A new surgical technique for treatment of short bowel syndrome. Lakartidningen. 2008;105:1849–1851.
  • Ismail A, Alkadhi A, Alnagaar O, et al. Serial transverse enteroplasty in intestinal atresia management. J Pediatr Surg. 2005;40:E5–6.
  • Wales PW, Dutta S. Serial transverse enteroplasty as primary therapy for neonates with proximal jejunal atresia. J Pediatr Surg. 2005;40:E31–34.
  • Cowles RA, Lobritto SJ, Stylianos S, et al. Serial transverse enteroplasty in a newborn patient. J Pediatr Gastroenterol Nutr. 2007;45:257–260.
  • Lobos PA, Calello SE, Busoni VB, et al. Neonatal Serial Transverse Enteroplasty (STEP): case report. Transplant Proc. 2016;48:528–531.
  • Wales PW, Jancelewicz T, Romao RL, et al. Delayed primary serial transverse enteroplasty as a novel management strategy for infants with congenital ultra-short bowel syndrome. J Pediatr Surg. 2013;48:993–999.
  • Duggan C, Piper H, Javid PJ, et al. Growth and nutritional status in infants with short-bowel syndrome after the serial transverse enteroplasty procedure. Clin Gastroenterol Hepatol. 2006;4:1237–1241.
  • Lourenço L, Campos M, Monteiro J, et al. Serial transverse enteroplasty (STEP): intermediate outcomes in children with short bowel syndrome. Eur J Pediatr. 2012;171:1265–1268.
  • Modi BP, Javid PJ, Jaksic T, et al. First report of the international serial transverse enteroplasty data registry: indications, efficacy, and complications. J Am Coll Surg. 2007;204:365–371.
  • Yoo KJ. Assesment of serial transverse enteroplasty: systematic review. Value Health. 2014;17:A372.
  • Garnett GM, Kang KH, Jaksic T, et al. First STEPs: serial transverse enteroplasty as a primary procedure in neonates with congenital short bowel. J Pediatr Surg. 2014;49:104–107. discussion 108.
  • Sudan D, Thompson J, Botha J, et al. Comparison of intestinal lengthening procedures for patients with short bowel syndrome. Ann Surg. 2007;246:593–601. discussion 601–604.
  • Bellolio RF, Klaassen LJ, Pulgar BD, et al. Serial transverse enteroplasty for short bowel syndrome. Case Report Rev Med Chil. 2010;138:478–482.
  • Zanfi C, Lauro A, Cescon M, et al. Comprehensive surgical intestinal rescue and transplantation program in adult patients: bologna experience. Transplant Proc. 2010;42:39–41.
  • Yaprak M, Erdoğan O, Oğus M. The STEP procedure in an adult patient with short bowel syndrome: a case report. Turk J Gastroenterol. 2011;22:333–336.
  • Fan S, Li Y, Zhang S, et al. Success of serial transverse enteroplasty in an adult with extreme short bowel syndrome: a case report. Int Surg. 2015;100:626–631.
  • Botey M, Alastrué A, Haetta H, et al. Long-Term results of serial transverse enteroplasty with neovalve creation for extreme short bowel syndrome: report of two cases. Case Rep Gastroenterol. 2017;11:229–240.
  • Modi BP, Langer M, Duggan C, et al. Serial transverse enteroplasty for management of refractory D-lactic acidosis in short-bowel syndrome. J Pediatr Gastroenterol Nutr. 2006;43:395–397.
  • Bueno J, Redecillas S, GarcÍa L, et al. Duodenal lengthening in short bowel with dilated duodenum. J Pediatr Surg. 2015;50:493–496.
  • Mangray H, Ghimenton F. Is STEP the future for patients requiring proctocolectomy? A new therapeutic proposal from pediatric experience. Clin Case Rep. 2015;3:558–561.
  • Jones BA, Hull MA, Potanos KM, et al. Report of 111 consecutive patients enrolled in the international serial transverse enteroplasty (STEP) data registry: a retrospective observational study. J Am Coll Surg. 2013;216:438–446.
  • Fernandes MA, Usatin D, Allen IE, et al. Improved enteral tolerance following step procedure: systematic literature review and meta-analysis. Pediatr Surg Int. 2016;32:921–926.
  • Oh PS, Fingeret AL, Shah MY, et al. Improved tolerance for enteral nutrition after serial transverse enteroplasty (STEP) in infants and children with short bowel syndrome–a seven-year single-center experience. J Pediatr Surg. 2014;49:1589–1592.
  • Mercer DF, Hobson BD, Gerhardt BK, et al. Serial transverse enteroplasty allows children with short bowel to wean from parenteral nutrition. J Pediatr. 2014;164:93–98.
  • Wales PW, de Silva N, Langer JC, et al. Intermediate outcomes after serial transverse enteroplasty in children with short bowel syndrome. J Pediatr Surg. 2007;42:1804–1810.
  • Oliveira C, de Silva N, Wales PW. Five-year outcomes after serial transverse enteroplasty in children with short bowel syndrome. J Pediatr Surg. 2012;47:931–937.
  • Ching YA, Fitzgibbons S, Valim C, et al. Long-term nutritional and clinical outcomes after serial transverse enteroplasty at a single institution. J Pediatr Surg. 2009;44:939–943.
  • Miraglia R, Catalano P, Maruzzelli L, et al. Balloon dilatation of postoperative small bowel anastomotic stricture in an infant with apple peel intestinal atresia after serial transverse enteroplasty and jejunoileal anastomosis. J Pediatr Surg. 2010;45:e25–88.
  • Bogue CO, Alzahrani AI, Wales PW, et al. Delayed, life-threatening lower gastrointestinal hemorrhage in an infant after serial transverse enteroplasty: treatment with transcatheter n-butyl-2-cyanoacrylate embolization. Pediatr Radiol. 2009;39:1098–1101.
  • Fisher JG, Stamm DA, Modi BP, et al. Gastrointestinal bleeding as a complication of serial transverse enteroplasty. J Pediatr Surg. 2014;49:745–749.
  • Gibbons TE, Casteel HB, Vaughan JF, et al. Staple line ulcers: a cause of chronic GI bleeding following STEP procedure. J Pediatr Surg. 2013;48:E1–3.
  • Fujioka WK, Cowles RA. Infectious complications following serial transverse enteroplasty in infants and children with short bowel syndrome. J Pediatr Surg. 2015;50:428–430.
  • Ehrlich PF, Mychaliska GB, Teitelbaum DH. The 2 STEP: an approach to repeating a serial transverse enteroplasty. J Pediatr Surg. 2007;42:819–822.
  • Andres AM, Thompson J, Grant W, et al. Repeat surgical bowel lengthening with the STEP procedure. Transplantation. 2008;85:1294–1299.
  • Barrett M, Demehri FR, Ives GC, et al. Taking a STEP back: assessing the outcomes of multiple STEP procedures. J Pediatr Surg. 2017;52:69–73.
  • Morikawa N, Kuroda T, Kitano Y, et al. Repeat STEP procedure to establish enteral nutrition in an infant with short bowel syndrome. Pediatr Surg Int. 2009;25:1007–1011.
  • Leung MW, Chan IH, Chao NS, et al. Serial transverse enteroplasty for short bowel syndrome: Hong Kong experience. Hong Kong Med J. 2012;18:35–39.
  • Oh JT, Koh H, Chang EY, et al. Second serial transverse enteroplasty procedure in an infant with extreme short bowel syndrome. J Korean Med Sci. 2012;27:701–703.
  • Bhalla VK, Pipkin WL, Hatley RM, et al. The use of multiple serial transverse enteroplasty (STEP) procedures for the management of intestinal atresia and short bowel syndrome. Am Surg. 2013;79:826–828.
  • Wester T, Borg H, Naji H, et al. Serial transverse enteroplasty to facilitate enteral autonomy in selected children with short bowel syndrome. Br J Surg. 2014;101:1329–1333.
  • Kang KH, Gutierrez IM, Zurakowski D, et al. Bowel re-dilation following serial transverse enteroplasty (STEP). Pediatr Surg Int. 2012;28:1189–1193.
  • Wester T, Lilja HE, Stenström P, et al. Absent ileocecal valve predicts the need for repeated step in children. Surgery. 2017;161:818–822.
  • Fusaro F, Hermans D, Wanty C, et al. Post-serial transverse enteroplasty bowel redilatation treated by longitudinal intestinal lengthening and tailoring procedure. J Pediatr Surg. 2012;47:e19–22.
  • Cserni T, Takayasu H, Muzsnay Z, et al. New idea of intestinal lengthening and tailoring. Pediatr Surg Int. 2011;27:1009–1013.
  • Mehrabi V, Mehrabi A, Jamshidi SH, et al. Modified spiral intestinal lengthening and tailoring for short bowel syndrome. Surg Innov. 2016;23:30–35.
  • Alberti D, Boroni G, Giannotti G, et al. “Spiral intestinal lenghtening and tailoring (SILT)” for a child with severely short bowel. Pediatr Surg Int. 2014;30:1169–1172.
  • Murphy F, Khalil BA, Gozzini S, et al. Controlled tissue expansion in the initial management of the short bowel state. World J Surg. 2011;35:1142–1145.
  • Coletta R, Aldeiri B, Morabito A. Institutional experience with spiral intestinal lengthening and tailoring. Eur J Pediatr Surg. 2018 Jun 19. [ Epub ahead of print].
  • Sako K, Blackman GE. The use of a reversed jejunal segment after massive resection of the small bowel. An experimental study. Am J Surg. 1962;103:202–205.
  • Sako K, Gerszi K, Marchetta FC. Nutritional effects of a short reversed jejunal segment. Arch Surg. 1964;89:1102–1105.
  • Bähr R, Flach A. Morphological and functional adaptation after massive resection of the small intestine: experiments using minipigs of the Göttingen strain. Prog Pediatr Surg. 1978;12:107–142.
  • Søndenaa K, Nesvik I, Nygaard K, et al. Mucosal surface area of a reversed intestinal segment in rats. Scand J Gastroenterol. 1991;26:1240–1246.
  • Uchiyama M, Iwafuchi M, Ohsawa Y, et al. Intestinal myoelectric activity and contractile motility in dogs with a reversed jejunal segment after extensive small bowel resection. J Pediatr Surg. 1992;27:686–690.
  • Uchiyama M, Iwafuchi M, Ohsawa Y, et al. Resulting long-term intestinal motility in dogs following construction of a reversed jejunal segment after extensive small bowel resection. J Pediatr Surg. 1994;29:1335–1338.
  • Uchiyama M, Iwafuchi M, Matsuda Y, et al. Changes in intestinal motility after massive small bowel resection with a reversed jejunal segment. J Smooth Muscle Res. 1996;32:17–26.
  • Thompson JS, Quigley EM, Adrian TE. Effect of reversed intestinal segments on intestinal structure and function. J Surg Res. 1995;58:19–27.
  • Devine RM, Kelly KA. Surgical therapy of the short bowel syndrome. Gastroenterol Clin North Am. 1989;18:603–618.
  • Thompson JS. Surgical approach to the short-bowel syndrome: procedures to slow intestinal transit. Eur J Pediatr Surg. 1999;9:263–266.
  • Billiauws L, Maggiori L, Joly F, et al. Medical and surgical management of short bowel syndrome. J Visc Surg. 2018;155:283–291.
  • Hofmann S. Surgical methods for adaptation of impaired absorption in cases of extensive resection of the small intestine in childhood. Padiatr Padol Suppl. 1975;3:47–53.
  • Hakami M, Moslehy A, Mosavy SH. Reversed jejunal segment used to treat the short bowel syndrome. Am Surg. 1975;41:432–435.
  • Pentlow BD. Intractable ileostomy diarrhoea associated with short small bowel treated by a reversed bowel segment. Proc R Soc Med. 1976;69:360–362.
  • Pigot F, Messing B, Chaussade S, et al. Severe short bowel syndrome with a surgically reversed small bowel segment. Dig Dis Sci. 1990;35:137–144.
  • Thompson JS, Langnas AN, Pinch LW, et al. Surgical approach to short-bowel syndrome. Experience in a population of 160 patients. Ann Surg. 1995;222:600–605. discussion 605–607.
  • Panis Y, Messing B, Rivet P, et al. Segmental reversal of the small bowel as an alternative to intestinal transplantation in patients with short bowel syndrome. Ann Surg. 1997;225:401–407.
  • Beyer-Berjot L, Joly F, Maggiori L, et al. Segmental reversal of the small bowel can end permanent parenteral nutrition dependency: an experience of 38 adults with short bowel syndrome. Ann Surg. 2012;256:739–744. discussion 744–745.
  • Thompson JS, Sudan DA, Gilroy R. Predicting outcome of procedures to slow intestinal transit. Transplant Proc. 2006;38:1838–1839.
  • Thompson JS. Reversed intestinal segment revisited. Transplant Proc. 2016;48:453–456.
  • Frongia G, Kessler M, Weih S, et al. Comparison of LILT and STEP procedures in children with short bowel syndrome – a systematic review of the literature. J Pediatr Surg. 2013;48:1794–1805.
  • Miyasaka EA, Brown PI, Teitelbaum DH. Redilation of bowel after intestinal lengthening procedures: an indicator for poor outcome. J Pediatr Surg. 2011;46:145–149.
  • Sueyoshi R, Woods Ignatoski KM, Okawada M, et al. Distraction-induced intestinal growth: the role of mechano-transduction mechanisms in a mouse model of short bowel syndrome. Tissue Eng Part A. 2014;20:830–841.
  • Rouch JD, Dunn JC. New insights and interventions for short bowel syndrome. Curr Pediatr Rep. 2017;5:1–5.
  • Sullins VF, Wagner JP, Suwarnasarn AT, et al. A novel biodegradable device for intestinal lengthening. J Pediatr Surg. 2014;49:109–113. discussion 113.
  • Fisher JG, Sparks EA, Khan FA, et al. Extraluminal distraction enterogenesis using shape-memory polymer. J Pediatr Surg. 2015;50:938–942.
  • Demehri FR, Freeman JJ, Fukatsu Y, et al. Development of an endoluminal intestinal lengthening device using a geometric intestinal attachment approach. Surgery. 2015;158:802–811.
  • Demehri FR, Utter B, Freeman JJ, et al. Development of an endoluminal intestinal attachment for a clinically applicable distraction enterogenesis device. J Pediatr Surg. 2016;51:101–106.
  • Sueyoshi R, Ralls MW, Teitelbaum DH. Glucagon-like peptide 2 increases efficacy of distraction enterogenesis. J Surg Res. 2013;184:365–373.
  • Rouch JD, Scott A, Jabaji ZB, et al. Basic fibroblast growth factor eluting microspheres enhance distraction enterogenesis. J Pediatr Surg. 2016;51:960–965.
  • Miyasaka EA, Okawada M, Utter B, et al. Application of distractive forces to the small intestine: defining safe limits. J Surg Res. 2010;163:169–175.
  • Coletta R, Olivieri C, Persano G, et al. Expanding intestinal segment using osmotic hydrogel: an in vivo study. J Biomed Mater Res B Appl Biomater. 2019;107:1304-1309.

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