Metabolomics studies in gastrointestinal cancer: a systematic review

References

• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Global Burden of Disease Cancer C, Fitzmaurice C, Allen C, Barber RM, et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncol. 2017 Apr 1;3(4):524–548.
   PubMed Web of Science ®Google Scholar
• Casamayor M, Morlock R, Maeda H, et al. Targeted literature review of the global burden of gastric cancer. Ecancermedicalscience. 2018;12:883.
   PubMed Web of Science ®Google Scholar
• Zeng H, Zheng R, Guo Y, et al. Cancer survival in China, 2003–2005: a population-based study. Int J Cancer. 2015 Apr 15;136(8):1921–1930.
   PubMed Web of Science ®Google Scholar
• Tachibana M, Kinugasa S, Shibakita M, et al. Surgical treatment of superficial esophageal cancer. Langenbecks Arch Surg. 2006 Aug;391(4):304–321.
   PubMed Web of Science ®Google Scholar
• Kim Y. American Cancer Society. Cancer. 2013;48(6):1289–1289.
   Google Scholar
• Park YH, Kim N. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer. J Cancer Prev. 2015 Mar;20(1):25–40.
   PubMedGoogle Scholar
• Burton C, Ma Y. Current trends in cancer biomarker discovery using urinary metabolomics: achievements and new challenges. Curr Med Chem. 2019;26(1):5–28.
   PubMed Web of Science ®Google Scholar
• Amantonico A, Urban PL, Zenobi R. Analytical techniques for single-cell metabolomics: state of the art and trends. Anal Bioanal Chem. 2010 Nov;398(6):2493–2504.
   PubMed Web of Science ®Google Scholar
• Zhang J, Bowers J, Liu L, et al. Esophageal cancer metabolite biomarkers detected by LC-MS and NMR methods. PLoS One. 2012;7(1):e30181.
   PubMed Web of Science ®Google Scholar
• Chan AW, Gill RS, Schiller D, et al. Potential role of metabolomics in diagnosis and surveillance of gastric cancer. World J Gastroenterol. 2014 Sep 28;20(36):12874–12882.
   PubMed Web of Science ®Google Scholar
• Liesenfeld DB, Habermann N, Toth R, et al. Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare). Metabolomics. 2015;11(4):998–1012.
   PubMed Web of Science ®Google Scholar
• Ranjan R, Sinha N. Nuclear magnetic resonance (NMR)-based metabolomics for cancer research. NMR Biomed. 2019 Oct;32(10):e3916.
   PubMed Web of Science ®Google Scholar
• Santosh Kumar Bharti RR. Metabolite identification in NMR-based metabolomics. Current Metabol. 2014;2:163–173.
   Google Scholar
• Kang YP, Ward NP, DeNicola GM. Recent advances in cancer metabolism: a technological perspective. Exp Mol Med. 2018 Apr 16; 50(4):31.
   PubMedGoogle Scholar
• Matsuda F. Technical challenges in mass spectrometry-based metabolomics. Mass Spectrom (Tokyo). 2016;5(2):S0052.
   PubMedGoogle Scholar
• Lu W, Zhang S, Teng X, et al. LC-MS and GC-MS based metabolomics platform for cancer research. Cancer Metab. 2014;2:S1.
   PubMedGoogle Scholar
• Wang Z, Cui B, Zhang F, et al. Development of a correlative strategy to discover colorectal tumor tissue derived metabolite biomarkers in plasma using untargeted metabolomics. Anal Chem. 2019 Feb 5;91(3):2401–2408.
   PubMed Web of Science ®Google Scholar
• Sun C, Li T, Song X, et al. Spatially resolved metabolomics to discover tumor-associated metabolic alterations. Proc Natl Acad Sci USA. 2019 Jan 2;116(1):52–57.
   PubMed Web of Science ®Google Scholar
• Eberlin LS, Tibshirani RJ, Jialing Z. Molecular assessment of surgical-resection margins of gastric cancer by mass-spectrometric imaging. PNAS. 2014;111(7):2436–2441.
   Web of Science ®Google Scholar
• Deng K, Lin S, Zhou L, et al. High levels of aromatic amino acids in gastric juice during the early stages of gastric cancer progression. PLoS One. 2012;7(11):e49434.
   PubMed Web of Science ®Google Scholar
• Choi JM, Park WS, Song KY, et al. Development of simultaneous analysis of tryptophan metabolites in serum and gastric juice - an investigation towards establishing a biomarker test for gastric cancer diagnosis. Biomed Chromatogr. 2016 Dec;30(12):1963–1974.
   PubMed Web of Science ®Google Scholar
• Deng K, Lin S, Zhou L, et al. Three aromatic amino acids in gastric juice as potential biomarkers for gastric malignancies. Anal Chim Acta. 2011 May 23;694(1–2):100–107.
   PubMed Web of Science ®Google Scholar
• NE HCB, Eller N. Potential of human saliva for nuclear magnetic resonance-based metabolomics and for health-related biomarker identification. Anal Chem. 2009;81(20):9188–9193.
   PubMedGoogle Scholar
• Ohshima M, Sugahara K, Kasahara K, et al. Metabolomic analysis of the saliva of Japanese patients with oral squamous cell carcinoma. Oncol Rep. 2017 May;37(5):2727–2734.
   PubMed Web of Science ®Google Scholar
• Shu J, Yu H, Du H, et al. Identification of N- and O-linked glycans recognized by AAL in saliva of patients with atrophic gastritis and gastric cancer. Cancer Biomark. 2018;22(4):669–681.
   PubMed Web of Science ®Google Scholar
• Fábián PFaPC TK, Genomics S. Transcriptomics and Proteomics: the emerging concept of the oral ecosystem and their use in the early diagnosis of cancer and other diseases. Curr Genomics. 2008;9:11–21.
   PubMed Web of Science ®Google Scholar
• Hedman J, Sjoman R, Sjostrom I, et al. Fluoride concentration in saliva after consumption of a dinner meal prepared with fluoridated salt. Caries Res. 2006;40(2):158–162.
   PubMed Web of Science ®Google Scholar
• Mochalski P, King J, Klieber M, et al. Blood and breath levels of selected volatile organic compounds in healthy volunteers. Analyst. 2013 Apr 7;138(7):2134–2145.
   PubMed Web of Science ®Google Scholar
• King J, Kupferthaler A, Frauscher B, et al. Measurement of endogenous acetone and isoprene in exhaled breath during sleep. Physiol Meas. 2012 Mar;33(3):413–428.
   PubMed Web of Science ®Google Scholar
• Haick H, Broza YY, Mochalski P, et al. Assessment, origin, and implementation of breath volatile cancer markers. Chem Soc Rev. 2014 Mar 7;43(5):1423–1449.
   PubMed Web of Science ®Google Scholar
• Wang Z, Yan L, Liang J, et al. NMR-based metabolomic techniques identify potential urinary biomarkers for early colorectal cancer detection. Oncotarget. 2017;8(62):105819–105831.
   PubMedGoogle Scholar
• Kim ER, Kwon HN, Nam H, et al. Urine-NMR metabolomics for screening of advanced colorectal adenoma and early stage colorectal cancer. Sci Rep. 2019 Mar 18;9(1):4786.
   PubMedGoogle Scholar
• Zhu J, Djukovic D, Deng L, et al. Colorectal cancer detection using targeted serum metabolic profiling. J Proteome Res. 2014 Sep 5;13(9):4120–4130.
   PubMed Web of Science ®Google Scholar
• Deng L, Gu H, Zhu J, et al. Combining NMR and LC/MS using backward variable elimination: metabolomics analysis of colorectal cancer, polyps, and healthy controls. Anal Chem. 2016 Aug 16;88(16):7975–7983.
   PubMed Web of Science ®Google Scholar
• Zhang H, Wang L, Hou Z, et al. Metabolomic profiling reveals potential biomarkers in esophageal cancer progression using liquid chromatography-mass spectrometry platform. Biochem Biophys Res Commun. 2017 Sep 9;491(1):119–125.
   PubMed Web of Science ®Google Scholar
• Zhu X, Wang K, Liu G, et al. Metabolic perturbation and potential markers in patients with esophageal cancer. Gastroenterol Res Pract. 2017;2017:5469597.
   PubMed Web of Science ®Google Scholar
• Liang W, Jie C, Longqi C, et al. 1H-NMR based metabonomic profiling of human esophageal cancer tissue. Mol Cancer. 2013;12(1):25.
   PubMedGoogle Scholar
• Jin H, Qiao F, Chen L, et al. Serum metabolomic signatures of lymph node metastasis of esophageal squamous cell carcinoma. J Proteome Res. 2014 Sep 5;13(9):4091–4103.
   PubMed Web of Science ®Google Scholar
• Gu J, Hu X, Shao W, et al. Metabolomic analysis reveals altered metabolic pathways in a rat model of gastric carcinogenesis. Oncotarget. 2016;7(37):60053–60073.
   PubMedGoogle Scholar
• Wang H, Zhang H, Deng P, et al. Tissue metabolic profiling of human gastric cancer assessed by 1 H NMR. Bmc Cancer. 2016;16(1):371.
   PubMedGoogle Scholar
• Xu JCY, Global ZR. Targeted metabolomics of esophageal squamous cell carcinoma discovers potential diagnostic and therapeutic biomarkers. Mol Cell Proteomics Mcp. 2013;12(5):1306–1318.
   PubMed Web of Science ®Google Scholar
• Reed MAC, Singhal R, Ludwig C, et al. Metabolomic evidence for a field effect in histologically normal and metaplastic tissues in patients with esophageal adenocarcinoma. Neoplasia. 2017 Mar;19(3):165–174.
   PubMed Web of Science ®Google Scholar
• Tan B, Qiu Y, Zou X, et al. Metabonomics identifies serum metabolite markers of colorectal cancer. J Proteome Res. 2013 Jun 7;12(6):3000–3009.
   PubMed Web of Science ®Google Scholar
• Chan AW, Mercier P, Schiller D, et al. (1)H-NMR urinary metabolomic profiling for diagnosis of gastric cancer. Br J Cancer. 2016 Jan 12;114(1):59–62.
   PubMed Web of Science ®Google Scholar
• Nishiumi S, Kobayashi T, Ikeda A, et al. A novel serum metabolomics-based diagnostic approach for colorectal cancer. PLoS One. 2012;7(7):e40459.
   PubMed Web of Science ®Google Scholar
• Sanchez-Espiridion B, Liang D, Ajani JA, et al. Identification of serum markers of esophageal adenocarcinoma by global and targeted metabolic profiling. Clin Gastroenterol Hepatol. 2015 Oct;13(10):1730–1737 e9.
   PubMed Web of Science ®Google Scholar
• Weljie AM, Jirik FR. Hypoxia-induced metabolic shifts in cancer cells: moving beyond the Warburg effect. Int J Biochem Cell Biol. 2011 Jul;43(7):981–989.
   PubMed Web of Science ®Google Scholar
• Ma H, Hasim A, Mamtimin B, et al. Plasma free amino acid profiling of esophageal cancer using high-performance liquid chromatography spectroscopy. World J Gastroenterol. 2014 Jul 14;20(26):8653–8659.
   PubMed Web of Science ®Google Scholar
• Miyagi Y, Higashiyama M, Gochi A, et al. Plasma free amino acid profiling of five types of cancer patients and its application for early detection. PLoS One. 2011;6(9):e24143.
   PubMed Web of Science ®Google Scholar
• Farshidfar F, Kopciuk KA, Hilsden R, et al. A quantitative multimodal metabolomic assay for colorectal cancer. BMC Cancer. 2018 Jan 4;18(1):26.
   PubMedGoogle Scholar
• Zhang X, Xu L, Shen J, et al. Metabolic signatures of esophageal cancer: NMR-based metabolomics and UHPLC-based focused metabolomics of blood serum. Biochim Biophys Acta. 2013 Aug;1832(8):1207–1216.
   PubMed Web of Science ®Google Scholar
• Lario S, Ramirez-Lazaro MJ, Sanjuan-Herraez D, et al. Plasma sample based analysis of gastric cancer progression using targeted metabolomics. Sci Rep. 2017 Dec 19;7(1):17774.
   PubMedGoogle Scholar
• Chen Y, Zhang J, Guo L, et al. A characteristic biosignature for discrimination of gastric cancer from healthy population by high throughput GC-MS analysis. Oncotarget. 2016;7(52):87496–87510.
   PubMedGoogle Scholar
• Brown DG, Rao S, Weir TL, et al. Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool. Cancer Metab. 2016;4:11.
   PubMed Web of Science ®Google Scholar
• Iorio E, Mezzanzanica D, Alberti P, et al. Alterations of choline phospholipid metabolism in ovarian tumor progression. Cancer Res. 2005 Oct 15;65(20):9369–9376.
   PubMed Web of Science ®Google Scholar
• Liu R, Peng Y, Li X, et al. Identification of plasma metabolomic profiling for diagnosis of esophageal squamous-cell carcinoma using an UPLC/TOF/MS platform. Int J Mol Sci. 2013 Apr 24;14(5):8899–8911.
   PubMed Web of Science ®Google Scholar
• Long Y, Sanchez-Espiridion B, Lin M, et al. Global and targeted serum metabolic profiling of colorectal cancer progression. Cancer. 2017 Oct 15;123(20):4066–4074.
   PubMed Web of Science ®Google Scholar
• Farshidfar F, Weljie AM, Kopciuk KA, et al. A validated metabolomic signature for colorectal cancer: exploration of the clinical value of metabolomics. Br J Cancer. 2016 Sep 27;115(7):848–857.
   PubMed Web of Science ®Google Scholar
• Xu J, Chen Y, Zhang R, et al. Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging. Sci Rep. 2016 Oct;11(6):35010.
   Google Scholar
• Vahabi F, Sadeghi S, Arjmand M, et al. Staging of colorectal cancer using serum metabolomics with (1)HNMR Spectroscopy. Iran J Basic Med Sci. 2017 Jul;20(7):835–840.
   PubMed Web of Science ®Google Scholar
• Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004 Nov;4(11):891–899.
   PubMed Web of Science ®Google Scholar
• Song H, Peng J-S, Dong-Sheng Y, et al. Serum metabolic profiling of human gastric cancer based on gas chromatography/mass spectrometry. Braz J Med Biol Res. 2012;45(1):78–85.
   PubMed Web of Science ®Google Scholar
• Qiu YCG. Su M Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS. J Proteome Res. 2009;10:4844–4850.
   Google Scholar
• Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 2009 May 22;324(5930):1029–1033.
   PubMed Web of Science ®Google Scholar
• Pan T, Gao L, Wu G, et al. Elevated expression of glutaminase confers glucose utilization via glutaminolysis in prostate cancer. Biochem Biophys Res Commun. 2015 Jan 2;456(1):452–458.
   PubMed Web of Science ®Google Scholar
• Haug U, Poole EM, Xiao L, et al. Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer. Genes Chromosomes Cancer. 2012 Jun;51(6):598–605.
   PubMed Web of Science ®Google Scholar
• Wise DR, Thompson CB. Glutamine addiction: a new therapeutic target in cancer. Trends Biochem Sci. 2010 Aug;35(8):427–433.
   PubMed Web of Science ®Google Scholar
• Metallo CM, Gameiro PA, Bell EL, et al. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature. 2011 Nov 20;481(7381):380–384.
   PubMed Web of Science ®Google Scholar
• Opitz CA, Litzenburger UM, Sahm F, et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature. 2011 Oct 5;478(7368):197–203.
   PubMed Web of Science ®Google Scholar
• Folgiero V, Goffredo BM, Filippini P. Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia. Oncotarget. 2014;5:2052–2064.
   PubMed Web of Science ®Google Scholar
• Locasale JW. Serine, glycine and one-carbon units: cancer metabolism in full circle. Nat Rev Cancer. 2013 Aug;13(8):572–583.
   PubMed Web of Science ®Google Scholar
• Glunde K, Penet MF, Jiang L, et al. Choline metabolism-based molecular diagnosis of cancer: an update. Expert Rev Mol Diagn. 2015 Jun;15(6):735–747.
   PubMed Web of Science ®Google Scholar
• Ueland PM. Choline and betaine in health and disease. J Inherit Metab Dis. 2011 Feb;34(1):3–15.
   PubMed Web of Science ®Google Scholar
• Kabarowski Janusz HSXY, Witte Owen N. Lysophosphatidylcholine as a ligand for immunoregulation. Biochem Pharmacol. 2002;64:161–167.
   PubMed Web of Science ®Google Scholar
• Tong H, Wang Y, Li Y, et al. Volatile organic metabolites identify patients with gastric carcinoma, gastric ulcer, or gastritis and control patients. Cancer Cell Int. 2017;17:108.
   PubMed Web of Science ®Google Scholar