3,030
Views
3
CrossRef citations to date
0
Altmetric
Meta-analysis

Dietary interventions for functional abdominal pain disorders in children: a systematic review and meta-analysis

ORCID Icon, , , , &
Pages 359-371 | Received 05 Jan 2022, Accepted 16 Mar 2022, Published online: 27 Mar 2022

References

  • Hyams JS, Di Lorenzo C, Saps M, et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2016;150(6):1456–1468e2.
  • Korterink JJ, Diederen K, Benninga MA, et al. Epidemiology of pediatric functional abdominal pain disorders: a meta-analysis. PLoS One. 2015;10(5):e0126982.
  • Youssef NN, Murphy TG, Langseder AL, et al. Quality of life for children with functional abdominal pain: a comparison study of patients’ and parents’ perceptions. Pediatrics. 2006;117(1):54–59.
  • Hoekman DR, Rutten JMTM, Vlieger AM, et al. Annual costs of care for pediatric irritable bowel syndrome, functional abdominal pain, and functional abdominal pain syndrome. J Pediatr. 2015;167(5):1103–1108.e2.
  • Lewis ML, Palsson OS, Whitehead WE, et al. Prevalence of functional gastrointestinal disorders in children and adolescents. J Pediatr. 2016;177:39–43.e3.
  • Assa A, Ish-Tov A, Rinawi F, et al. School attendance in children with functional abdominal pain and inflammatory bowel diseases. J Pediatr Gastroenterol Nutr. 2015;61(5):553–557.
  • Dhroove G, Chogle A, Saps M. A million-dollar work-up for abdominal pain: is it worth it? J Pediatr Gastroenterol Nutr. 2010;51(5):579–583.
  • Newlove-Delgado T, Martin AE, Abbott RA, et al. Dietary interventions for recurrent abdominal pain in childhood. Cochrane Database Syst Rev. 2017;276–278. DOI:https://doi.org/10.1093/pch/pxz132.
  • Rexwinkel R, de Bruijn CMA, Gordon M, et al. Pharmacologic treatment in functional abdominal pain disorders in children: a systematic review. Pediatrics. 2021;147(6):e2020042101. DOI:https://doi.org/10.1542/peds.2020-042101.
  • de Bruijn CMA, Rexwinkel R, Gordon M, et al. Antidepressants for functional abdominal pain disorders in children and adolescents. Cochrane Database Syst Rev. 2021;2(2):CD008013. DOI:https://doi.org/10.1002/14651858.CD008013.pub3.
  • Korterink J, Devanarayana NM, Rajindrajith S, et al. Childhood functional abdominal pain: mechanisms and management. Nat Rev Gastroenterol Hepatol. 2015;12(3):159–171.
  • Chumpitazi BP, Shulman RJ. Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome. Mol Cell Pediatr. 2016;3(1). DOI:https://doi.org/10.1186/s40348-016-0036-8
  • Drossman DA, Tack J, Ford AC, et al. Neuromodulators for functional gastrointestinal disorders (disorders of gut−brain interaction): a Rome foundation working team report. Gastroenterology. 2018;154(4):1140–1171.e1.
  • Drossman DA. Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV. Gastroenterology. 2016;150(6):1262–1279e2.
  • Oświęcimska J, Szymlak A, Roczniak W, et al. New insights into the pathogenesis and treatment of irritable bowel syndrome. Adv Med Sci. 2017;62(1):17–30.
  • Camilleri M. Diagnosis and treatment of irritable bowel syndrome: a review. JAMA - J Am Med Assoc. 2021;325(9):865–877.
  • Ford A, Lacy B, Talley NJ. Irritable bowel syndrome. N Engl J Med. 2017;376(26):66–78.
  • Carlson MJ, Moore CE, Tsai CM, et al. Child and parent perceived food-induced gastrointestinal symptoms and quality of life in children with functional gastrointestinal disorders. J Acad Nutr Diet. 2014;114(3):403–413.
  • Chumpitazi BP, Weidler EM, Lu DY, et al. Self-Perceived Food Intolerances Are Common and Associated with Clinical Severity in Childhood Irritable Bowel Syndrome. J Acad Nutr Diet. 2016;116(9):1458–1464.
  • Reed-Knight B, Squires M, Chitkara DK, et al. Adolescents with irritable bowel syndrome report increased eating-associated symptoms, changes in dietary composition, and altered eating behaviors: a pilot comparison study to healthy adolescents. Neurogastroenterol Motil. 2016;28(12):1915–1920.
  • Eswaran S, Tack J, Chey WD. Food: the forgotten factor in the irritable bowel syndrome. Gastroenterol Clin North Am. 2011;40(1):141–162.
  • Hayes P, Corish C, O’Mahony E, et al. A dietary survey of patients with irritable bowel syndrome. J Hum Nutr Diet. 2014;27:36–47.
  • Aguilera-Lizarraga J, Florens MV, Viola MF, et al. Local immune response to food antigens drives meal-induced abdominal pain. Nature. 2021;590(7844):151–156.
  • Gibson PR, Shepherd SJ. Food choice as a key management strategy for functional gastrointestinal symptoms. Am J Gastroenterol. 2012;107(5):657–666.
  • Horst S, Shelby G, Anderson J, et al. Predicting persistence of functional abdominal pain from childhood into young adulthood. Clin Gastroenterol Hepatol. 2014;12(12):2026–2032.
  • Zeevenhooven J, Rexwinkel R, Van Berge Henegouwen VWA, et al. A core outcome set for clinical trials in pediatric functional abdominal pain disorders. J Pediatr. 2020;221:115–122.e5.
  • Higgins JPT, Altman DG, Gotzsche PC, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343(oct18 2):1–9.
  • Guyatt GH, Oxman AD, Vist GE, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. Chinese J Evidence-Based Med. 2009;9:8–11.
  • Schünemann HJ, Vist GE, Higgins JPT, et al. Chapter 12: interpreting results and drawing conclusions. Cochrane Handb Syst Rev Interv. 2019;403–431. DOI:https://doi.org/10.1002/9781119536604.ch15.
  • Abbott RA, Martin AE, Newlove-Delgado TV, et al. Recurrent abdominal pain in children: summary evidence from 3 systematic reviews of treatment effectiveness. J Pediatr Gastroenterol Nutr. 2018;67(1):23–33.
  • Pourmand H, Esmaillzadeh A. Consumption of a low fermentable oligo-, di-, mono-saccharides, and polyols diet and irritable bowel syndrome: a systematic review. Int J Prev Med. 2017;8. DOI:https://doi.org/10.4103/ijpvm.IJPVM_175_17
  • Rutten JMTM, Korterink JJ, Venmans L, et al. Nonpharmacologic treatment of functional abdominal pain disorders: a systematic review. Pediatrics. 2015;135(3):522–535.
  • Scarpato E, Auricchio R, Penagini F, et al. Efficacy of the gluten free diet in the management of functional gastrointestinal disorders: a systematic review on behalf of the Italian Society of Paediatrics. Ital J Pediatr. 2019;45(1):1–11.
  • Turco R, Salvatore S, Miele E, et al. Does a low FODMAPs diet reduce symptoms of functional abdominal pain disorders? A systematic review in adult and paediatric population, on behalf of Italian Society of Pediatrics. Ital J Pediatr. 2018;44(1):1–14.
  • Weydert JA, Ball TM, Davis MF. Systematic review of treatments for recurrent abdominal pain. Pediatrics. 2003;111(1):e1–e11.
  • Anheyer D, Frawley J, Koch AK, et al. Herbal medicines for gastrointestinal disorders in children and adolescents: a systematic review. Pediatrics. 2017;139(6). DOI:https://doi.org/10.1542/peds.2017-0062.
  • Axelrod CH, Saps M. The role of fiber in the treatment of functional gastrointestinal disorders in children. Nutrients. 2018;10(11):1650.
  • Chiou E, Nurko S. Management of functional abdominal pain and irritable bowel syndrome in children and adolescents. Expert Rev Gastroenterol Hepatol. 2010;4(3):293–304.
  • Chumpitazi BP, Shulman RJ. Dietary carbohydrates and childhood functional abdominal pain. Ann Nutr Metab. 2016;68(Suppl. 1):8–17.
  • Duncanson KR, Talley NJ, Walker MM, et al. Food and functional dyspepsia: a systematic review. J Hum Nutr Diet. 2018;31(3):390–407.
  • Horvath A, Szajewska H. Probiotics, prebiotics, and dietary fiber in the management of functional gastrointestinal disorders. World Rev Nutr Diet. 2013;108:40–48.
  • Huertas-Ceballos A, Logan S, Bennett C, et al. Pharmacological interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood. Cochrane Database Syst Rev. 2008. DOI:https://doi.org/10.1002/14651858.CD003017.pub2
  • Paul SP, Basude D. Non-pharmacological management of abdominal pain-related functional gastrointestinal disorders in children. World J Pediatr. 2016;12(4):389–398.
  • Feldman W. The use of dietary fiber in the management of simple, childhood, idiopathic, recurrent, abdominal pain. Am J Dis Child. 1985;139(12):1216.
  • Horvath A, Dziechciarz P, Szajewska H. Glucomannan for abdominal pain-related functional gastrointestinal disorders in children: a randomized trial. World J Gastroenterol. 2013;19(20):3062–3068.
  • Wirth S, Klodt C, Wintermeyer P, et al. Positive or negative fructose breath test results do not predict response to fructose restricted diet in children with recurrent abdominal pain: results from a prospective randomized trial. Klin Padiatr. 2014;226(5):268–273.
  • Başturk A, Artan R, Yilmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: a randomized controlled trial. Turkish J Gastroenterol. 2016;27(5):439–443.
  • Jagadeesh MVR, Thapa BR, Lal SB, et al. Efficacy of oral psyllium versus placebo in pediatric irritable bowel syndrome: a double blind randomized control trial.
  • Romano C, Comito D, Famiani A, et al. Partially hydrolyzed guar gum in pediatric functional abdominal pain. World J Gastroenterol. 2013;19(2):235–240.
  • Boradyn KM, Przybyłowicz KE, Jarocka-Cyrta E. Low FODMAP diet is not effective in children with functional abdominal pain: a randomized controlled trial. Ann Nutr Metab. 2021;76(5):334–344.
  • Chumpitazi BP, McMeans AR, Vaughan A, et al. Fructans exacerbate symptoms in a subset of children with irritable bowel syndrome. Clin Gastroenterol Hepatol. 2018;16(2):219–225.e1.
  • Arrouk R, Herdes RE, Karpinski AC, et al. Serum-derived bovine immunoglobulin for children with diarrhea-predominant irritable bowel syndrome. Pediatr Heal Med Ther. 2018;9:129–133.
  • El Amrousy D, Hassan S, El Ashry H, et al. Vitamin D supplementation in adolescents with irritable bowel syndrome: is it useful? A randomized controlled trial. Saudi J Gastroenterol. 2018;24(2):109–114.
  • Shulman RJ, Hollister EB, Cain K, et al. Psyllium fiber reduces abdominal pain in children with irritable bowel syndrome in a randomized, double-blind trial. Clin Gastroenterol Hepatol. 2017;15(5):712–719.e4.
  • Chumpitazi BP, Cope JL, Hollister EB, et al. Randomised clinical trial: gut microbiome biomarkers are associated. Aliment Pharmacol Ther. 2015;42(4):418–427.
  • Ai Y, Jane J-L. Macronutrients in corn and human nutrition. Compr Rev Food Sci Food Saf. 2016;15(3):581–598.
  • Korczak R, Kamil A, Fleige L, et al. Dietary fiber and digestive health in children. Nutr Rev. 2017;75(4):241–259.
  • Kline RM, Kline JJ, Di Palma J, et al. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr. 2001;138(1):125–128.
  • Gordon M, Farrell M, Thomas AG, et al. Probiotics for management of functional abdominal pain disorders in children. Cochrane Database Syst Rev. 2017;2017(11):CD012849.
  • Bellini M, Rossi A. Is a low FODMAP diet dangerous? Tech Coloproctol. 2018;22(8):569–571.
  • Gibson PR, Shepherd SJ. Evidence-based dietary management of functional gastrointestinal symptoms: the FODMAP approach. J Gastroenterol Hepatol. 2010;25(2):252–258.
  • Staudacher HM, Whelan K. The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS. Gut. 2017;66(8): 1517 LP – 1527.
  • Lacy BE, Pimentel M, Brenner DM, et al. ACG clinical guideline: management of irritable bowel syndrome. Am J Gastroenterol. 2021;116(1):17–44.
  • van Lanen AS, de Bree A, Greyling A. Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis. Eur J Nutr. 2021. DOI:https://doi.org/10.1007/s00394-020-02473-0
  • Rej A, Shaw CC, Buckle RL, et al. The low FODMAP diet for IBS; A multicentre UK study assessing long term follow up. Dig liver Dis Off J Ital Soc Gastroenterol Ital Assoc Study Liver. 2021. DOI:https://doi.org/10.1016/j.dld.2021.05.004.
  • Alfaro-Cruz L, Heitkemper M, Chumpitazi BP, et al. Literature review: dietary intervention adherence and adherence barriers in functional gastrointestinal disorder studies. J Clin Gastroenterol. 2020;54:203–211.
  • Lackner S, Malcher V, Enko D, et al. Histamine-reduced diet and increase of serum diamine oxidase correlating to diet compliance in histamine intolerance. Eur J Clin Nutr. 2019;73(1):102–104.
  • Cremon C, Wrona D, Barbaro MR, et al. The effect of Zespri green kiwifruit on digestive functions in constipated patients: a randomized, controlled, single-blind, cross over study. Neurogastroenterol Motil. 2019;31. DOI:https://doi.org/10.1111/nmo.13627.
  • Biesiekierski JR, Newnham ED, Irving PM, et al. Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blind randomized placebo-controlled trial. Off J Am Coll Gastroenterol | ACG. 2011;106(3):508–514.
  • Barbaro MR, Cremon C, Wrona D, et al. Non-celiac gluten sensitivity in the context of functional gastrointestinal disorders. Nutrients. 2020;12(12):3735.
  • Saps M, van Tilburg MAL, Lavigne JV, et al. Recommendations for pharmacological clinical trials in children with irritable bowel syndrome: the Rome foundation pediatric subcommittee on clinical trials. Neurogastroenterol Motil. 2016;28(11):1619–1631.
  • Williamson PR, Altman DG, Bagley H, et al. The COMET Handbook: version 1.0. Trials. 2017;18(S3):280.
  • Martin AE, Newlove-Delgado TV, Abbott RA RA, et al. Pharmacological interventions for recurrent abdominal pain in childhood. Cochrane Database Syst Rev. 2017;3(3):CD010973.
  • Santucci NR, Saps M, van Tilburg MA. New advances in the treatment of paediatric functional abdominal pain disorders. Lancet Gastroenterol Hepatol. 2020;5(3):316–328.