1,389
Views
3
CrossRef citations to date
0
Altmetric
Original Research

Overprescription of short-acting β2-agonists is associated with poor asthma symptom control: results from five Middle Eastern countries included in the SABINA International (III) study

ORCID Icon, , , , , , , & show all
Pages 833-847 | Received 16 Feb 2022, Accepted 06 Jul 2022, Published online: 24 Aug 2022

References

  • Global asthma network (GAN) [Internet]. The global asthma report (2018). [cited 2021 Oct 20]. Available from: http://www.globalasthmareport.org
  • Song WJ, Kang MG, Chang YS, et al. Epidemiology of adult asthma in Asia: toward a better understanding. Asia Pac Allergy. 2014;4(2):75–85.
  • Khadadah M, Mahboub B, Al-Busaidi NH, et al. Asthma insights and reality in the Gulf and the near East. Int J Tuberc Lung Dis. 2009;13(8):1015–1022.
  • Alzaabi A, Alseiari M, Mahboub B. Economic burden of asthma in Abu Dhabi: a retrospective study. Clinicoecon Outcomes Res. 2014;6:445–450.
  • Tarraf H, Al-Jahdali H, Al Qaseer AH, et al. Asthma control in adults in the Middle East and North Africa: results from the ESMAA study. Respir Med. 2018;138:64–73.
  • Mungan D, Aydin O, Mahboub B, et al. Burden of disease associated with asthma among the adult general population of five Middle Eastern countries: results of the SNAPSHOT program. Respir Med. 2018;139:55–64.
  • Tarraf H, Aydin O, Mungan D, et al. Prevalence of asthma among the adult general population of five Middle Eastern countries: results of the SNAPSHOT program. BMC Pulm Med. 2018;18(1):68.
  • Al-Jahdali H, Wali S, Salem G, et al. Asthma control and predictive factors among adults in Saudi Arabia: results from the Epidemiological Study on the Management of Asthma in Asthmatic Middle East Adult Population study. Ann Thorac Med. 2019;14(2):148–154.
  • Dusser D, Montani D, Chanez P, et al. Mild asthma: an expert review on epidemiology, clinical characteristics and treatment recommendations. Allergy. 2007;62(6):591–604.
  • Price D, Fletcher M, van der Molen T. Asthma control and management in 8,000 European patients: the REcognise Asthma and LInk to Symptoms and Experience (REALISE) survey. NPJ Prim Care Respir Med. 2014;24:14009.
  • Suruki RY, Daugherty JB, Boudiaf N, et al. The frequency of asthma exacerbations and healthcare utilization in patients with asthma from the UK and USA. BMC Pulm Med. 2017;17(1):74.
  • Global Initiative for Asthma [Internet]. Global strategy for asthma management and prevention; 2022. [cited 2021 Jun 15 2022]. Available from: https://ginasthma.org.
  • Global Initiative for Asthma [Internet]. Global strategy for asthma management and prevention; 2017. [cited 2020 Feb 27]. Available from: https://ginasthma.org/gina-reports
  • Aldridge RE, Hancox RJ, Robin Taylor D, et al. Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. Am J Respir Crit Care Med. 2000;161(5):1459–1464.
  • Cabrera CS, Nan C, Lindarck N, et al. SABINA: global programme to evaluate prescriptions and clinical outcomes related to short-acting β2-agonist use in asthma. Eur Respir J. 2020;55(2):1901858.
  • Kaplan A, Mitchell PD, Cave AJ, et al. Effective asthma management: is it time to let the air out of SABA? J Clin Med. 2020;9(4):921.
  • Global Initiative for Asthma [Internet]. Global strategy for asthma management and prevention; 2019. [cited 2020 Jan 13]. Available from: https://ginasthma.org
  • Reddel HK, FitzGerald JM, Bateman ED, et al. GINA 2019: a fundamental change in asthma management: treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents. Eur Respir J. 2019;53(6):1901046.
  • Azzi EA, Kritikos V, Peters MJ, et al. Understanding reliever overuse in patients purchasing over-the-counter short-acting beta2 agonists: an Australian community pharmacy-based survey. BMJ Open. 2019;9(8):e028995.
  • Davidsen JR. Drug utilization and asthma control among young Danish adults with asthma. Analyses of trends and determinants. Dan Med J. 2012;59(8):B4501.
  • FitzGerald JM, Tavakoli H, Lynd LD, et al. The impact of inappropriate use of short acting beta agonists in asthma. Respir Med. 2017;131:135–140.
  • Hull SA, McKibben S, Homer K, et al. Asthma prescribing, ethnicity and risk of hospital admission: an analysis of 35,864 linked primary and secondary care records in East London. NPJ Prim Care Respir Med. 2016;26:16049.
  • Sadatsafavi M, Tavakoli H, Lynd L, et al. Has asthma medication use caught up with the evidence?: a 12-year population-based study of trends. Chest. 2017;151(3):612–618.
  • Alzaabi A, Idrees M, Behbehani N, et al. Cross-sectional study on asthma insights and management in the Gulf and Russia. Allergy Asthma Proc. 2018;39(6):430–436.
  • Bateman ED, Price DB, Wang H-C, et al. Short-acting β2-agonist prescriptions are associated with poor clinical outcomes of asthma: the multi-country, cross-sectional SABINA III study. Eur Respir J. 2022 59 5 2101402.
  • Reddel HK, Taylor DR, Bateman ED, et al. on behalf of the American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med. 2009;180(1):59–99.
  • World Health Organization [Internet]. Obesity and overweight; 2021. [cited 2021 Oct 4]. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
  • Alavinezhad A, Boskabady MH. The prevalence of asthma and related symptoms in Middle East countries. Clin Respir J. 2018;12(3):865–877.
  • Alzaabi A, Al-Kaabi J, Al-Maskari F, et al. Prevalence of diabetes and cardio-metabolic risk factors in young men in the United Arab Emirates: a cross-sectional national survey. Endocrinol Diabetes Metab. 2019;2(4):e00081.
  • Bel EH. Another piece to the puzzle of the “obese female asthma” phenotype. Am J Respir Crit Care Med. 2013;188(3):263–264.
  • Ford ES. The epidemiology of obesity and asthma. J Allergy Clin Immunol. 2005;115(5):897–909. quiz 910.
  • Khattab A, Javaid A, Iraqi G, et al. Breathe Study Group, Smoking habits in the Middle East and North Africa: results of the BREATHE study. Respir Med. 2012;106(Suppl 2):S16–24.
  • Kharroubi AT, Darwish HM. Diabetes mellitus: the epidemic of the century. World J Diabetes. 2015;6(6):850–867.
  • Meo SA, Usmani AM, Qalbani E. Prevalence of type 2 diabetes in the Arab world: impact of GDP and energy consumption. Eur Rev Med Pharmacol Sci. 2017;21(6):1303–1312.
  • Ross S, Grant A, Counsell C, et al. Barriers to participation in randomised controlled trials: a systematic review. J Clin Epidemiol. 1999;52(12):1143–1156.
  • Taft T, Weir C, Kramer H, et al. Primary care perspectives on implementation of clinical trial recruitment. J Clin Transl Sci. 2019;4(1):61–68.
  • Al-Busaidi N, Soriano JB. Asthma control in Oman: national results within the Asthma Insights and Reality in the Gulf and the Near East (AIRGNE) study. Sultan Qaboos Univ Med J. 2011;11(1):45–51.
  • Alrabiah AL, Elsaid T, Tourkmani A. Determinants of family medicine physicians’ knowledge and application of asthma management guidelines at primary healthcare centers in Riyadh, Saudi Arabia. J Fam Med Prim Care. 2018;7(5):927–936.
  • Noibi S, Mohy A, Gouhar R, et al. Asthma control factors in the Gulf Cooperation Council (GCC) countries and the effectiveness of ICS/LABA fixed dose combinations: a dual rapid literature review. BMC Public Health. 2020;20(1):1211.
  • Khaltaev N. GARD, a new way to battle with chronic respiratory diseases, from disease oriented programmes to global partnership. J Thorac Dis. 2017;9(11):4676–4689.
  • Yorgancıoğlu A, Gemicioglu B, Ekinci B, et al. Asthma in the context of Global Alliance against Respiratory Diseases (GARD) in Turkey. J Thorac Dis. 2018;10(3):2052–2058.
  • Nwaru BI, Ekström M, Hasvold P, et al. Overuse of short-acting β2-agonists in asthma is associated with increased risk of exacerbation and mortality: a nationwide cohort study of the global SABINA programme. Eur Respir J. 2020;55(4):1901872.
  • Wang C-Y, Lai C-C, Wang Y-H, et al. The prevalence and outcome of short-acting β2-agonists overuse in asthma patients in Taiwan. NPJ Prim Care Respir Med. 2021;31(1):19.
  • Worth H, Criée CP, Vogelmeier CF, et al. Prevalence of overuse of short-acting beta-2 agonists (SABA) and associated factors among patients with asthma in Germany. Respir Res. 2021;22 1 :108.
  • Ferris TG, Blumenthal D, Woodruff PG, et al. Insurance and quality of care for adults with acute asthma. J Gen Intern Med. 2022;17(12):905–913.
  • Tavakoli H, FitzGerald MJ, Lynd LD, et al. Predictors of inappropriate and excessive use of reliever medications in asthma: a 16-year population-based study. BMC Pulm Med. 2018;18(1):33.
  • Reddel HK, Ampon RD, Sawyer SM, et al. Risks associated with managing asthma without a preventer: urgent healthcare, poor asthma control and over-the-counter reliever use in a cross-sectional population survey. BMJ Open. 2017;7(9):e016688.
  • Partridge MR, van der Molen T, Myrseth S-E, et al. Attitudes and actions of asthma patients on regular maintenance therapy: the INSPIRE study. BMC Pulm Med. 2006;6():13.
  • Khalifeh MM, Moore ND, Salameh PR. Self-medication misuse in the Middle East: a systematic literature review. Pharmacol Res Perspect. 2017;5(4):e00323.
  • Bloom CI, Cabrera C, Arnetorp S, et al. Asthma-related health outcomes associated with short-acting β2-agonist inhaler use: an observational UK study as part of the SABINA global program. Adv Ther. 2020;37(10):4190–4208.
  • Stanford RH, Shah MB, D’Souza AO, et al. Short-acting β-agonist use and its ability to predict future asthma-related outcomes. Ann Allergy Asthma Immunol. 2012;109(6):403–407.
  • Sullivan PW, Ghushchyan VH, Globe G, et al. Oral corticosteroid exposure and adverse effects in asthmatic patients. J Allergy Clin Immunol. 2018;141(1):110–116.e7.
  • Chung LP, Upham JW, Bardin PG, et al. Rational oral corticosteroid use in adult severe asthma: a narrative review. Respirology. 2020;25(2):161–172.
  • Price DB, Trudo F, Voorham J, et al. Adverse outcomes from initiation of systemic corticosteroids for asthma: long-term observational study. J Asthma Allergy. 2018;11:193–204.