Is there cardiac autonomic dysfunction in children and adolescents with exercise-induced bronchospasm?

References

• Bonini M, Palange P. Exercise-induced bronchoconstriction: new evidence in pathogenesis, diagnosis and treatment. Asthma Res Pr. 2015;1(1):1–6. doi: 10.1186/s40733-015-0004-4
   PubMedGoogle Scholar
• Parsons JP, Hallstrand TS, Mastronarde JG, et al. An official American thoracic society clinical practice guideline: exercise-induced bronchoconstriction. Am J Respir Crit Care Med. 2013;187(9):1016–1027. doi: 10.1164/rccm.201303-0437ST. online supplement.
   PubMed Web of Science ®Google Scholar
• Aguiar K, Anzolin M, Zhang L. Global prevalence of exercise-induced bronchoconstriction in childhood: a meta-analysis. Pediatr Pulmonol. 2018;53(4):412–425. doi: 10.1002/ppul.23951
   PubMed Web of Science ®Google Scholar
• Weiler JM, Brannan JD, Randolph CC, et al. Exercise-induced bronchoconstriction update—2016. J Allergy Clin Immunol. 2016;138(5):1292–1295.e36. doi: 10.1016/j.jaci.2016.05.029
   PubMed Web of Science ®Google Scholar
• Hallstrand TS, Leuppi JD, Joos G, et al. ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing. Eur Respir J. 2018;52(5):1801033. doi: 10.1183/13993003.01033-2018
   PubMed Web of Science ®Google Scholar
• Wanrooij VHM, Willeboordse M, Dompeling E, et al. Exercise training in children with asthma: a systematic review. Br J Sport Med. 2014;48(13):1024–1031. doi: 10.1136/bjsports-2012-091347
   PubMed Web of Science ®Google Scholar
• Dantas FMNA, Correia MAV, Silva AR, et al. Mothers impose physical activity restrictions on their asthmatic children and adolescents: an analytical cross-sectional study. BMC Public Health. 2014;14(1):1–7. doi: 10.1186/1471-2458-14-287
   PubMed Web of Science ®Google Scholar
• Tikkakoski AP, Tikkakoski A, Kivistö JE, et al. Association of air humidity with incidence of exercise‐induced bronchoconstriction in children. Pediatr Pulmonol. 2019;54(11):1830–1836. doi: 10.1002/ppul.24471
   PubMed Web of Science ®Google Scholar
• Lin L-L, Huang S-J, Ou L-S, et al. Exercise-induced bronchoconstriction in children with asthma: an observational cohort study. J Microbiol Immunol Infect. 2019;52(3):471–479. doi: 10.1016/j.jmii.2017.08.013
   PubMedGoogle Scholar
• Crapo RO, Casaburi R, Coates AL, et al. American Thoracic Society guidelines for methacholine and exercise challenge testing -1999. Am J Respir Crit Care Med. 2000;161:309–329.
   PubMed Web of Science ®Google Scholar
• Roca J, Whipp B, Augusti A, et al. Clinical exercise testing with reference to lung diseases: indications, standardization and interpretation strategies. ERS Task force on standardization of clinical exercise testing. Eur Respir J. 1997;10:2662–2689.
   PubMed Web of Science ®Google Scholar
• Rodrigues Filho EA, Rizzo JÂ, Gonçalves AV, et al. Exercise-induced bronchospasm in children and adolescents with allergic rhinitis by treadmill and hyperventilation challenges. Respir med. 2018;138:102–106. doi: 10.1016/j.rmed.2018.04.001
   PubMed Web of Science ®Google Scholar
• Rizzo JÂ, de Rodrigues Filho EA, Gonçalves AV, et al. Reproducibility of eucapnic voluntary hyperpnoea for exercise‐induced bronchoconstriction diagnosis in asthmatic children and adolescents. Pediatr Allergy Immunol. 2021;32(8):1700–1708. doi: 10.1111/pai.13610
   PubMed Web of Science ®Google Scholar
• Rizzo JÂ, de Barros Albuquerque LCB, Medeiros D, et al. Ventilation rates achieved in eucapnic voluntary hyperpnea challenge and exercise-induced bronchoconstriction diagnosis in young patients with asthma. Lung. 2022;200(2):229–236. doi: 10.1007/s00408-022-00519-0
   PubMed Web of Science ®Google Scholar
• Pumprla J, Howorka K, Groves D, et al. Functional assessment of heart rate variability: physiological basis and practical applications. Int J Cardiol. 2002;84(1):1–14. doi: 10.1016/S0167-5273(02)00057-8
   PubMed Web of Science ®Google Scholar
• Fujii H, Fukutomi O, Inoue R, et al. Autonomic regulation after exercise evidenced by spectral analysis of heart rate variability in asthmatic children. Ann Allergy Asthma Immunol. 2000;85(3):233–237. doi: 10.1016/S1081-1206(10)62472-6
   PubMed Web of Science ®Google Scholar
• Garcia-Araújo AS, Pires Di Lorenzo VA, Labadessa IG, et al. Increased sympathetic modulation and decreased response of the heart rate variability in controlled asthma. J Asthma. 2015;52(3):246–253. doi: 10.3109/02770903.2014.957765
   PubMed Web of Science ®Google Scholar
• Vanderlei LCM, Pastre CM, Hoshi RA, et al. Noções básicas de variabilidade da frequência cardíaca e sua aplicabilidade clínica. Rev Bras Cir Cardiovasc. 2009;24(2):205–217. doi: 10.1590/S0102-76382009000200018
   PubMed Web of Science ®Google Scholar
• Catai AM, Pastre CM, de Godoy MF, et al. Heart rate variability: are you using it properly? Standardisation checklist of procedures. Brazilian Journal Of Physical Therapy. 2020;24(2):91–102. doi: 10.1016/j.bjpt.2019.02.006
   PubMed Web of Science ®Google Scholar
• Jin G-S, Li X-L, Jin Y-Z, et al. Role of peripheral vestibular receptors in the control of blood pressure following hypotension. Korean J Physiol Pharmacol. 2018;22(4):363. doi: 10.4196/kjpp.2018.22.4.363
   PubMed Web of Science ®Google Scholar
• Frontoni S, Bracaglia D, Gigli F. Relationship between autonomic dysfunction, insulin resistance and hypertension, in diabetes. Nutr Metab Cardiovasc Dis. 2005;15(6):441–449. doi: 10.1016/j.numecd.2005.06.010
   PubMed Web of Science ®Google Scholar
• Schiwe D, Vendrusculo FM, Becker NA, et al. Impact of asthma on heart rate variability in children and adolescents: systematic review and meta‐analysis. Pediatr Pulmonol. 2023;58(5):1310–1321. doi: 10.1002/ppul.26340
   PubMed Web of Science ®Google Scholar
• Lewis MJ, Short AL, Lewis KE. Autonomic nervous system control of the cardiovascular and respiratory systems in asthma. Respir Med Med. 2006;100(10):1688–1705. doi: 10.1016/j.rmed.2006.01.019
   PubMed Web of Science ®Google Scholar
• Ahmadian M, Dabidi Roshan V, Rezvan K, et al. Impact of exercise in high-humidity on heart rate variability and salivary oxidative stress in obese and lightweight asthmatic children. J Sport Med Phys Fit. 2020;60(5):60. doi: 10.23736/S0022-4707.20.10312-8
   Web of Science ®Google Scholar
• Rezvan K, Dabidi Roshan V, Mahmudi SA. Short-term heart rate variability in asthmatic obese children: effect of exhaustive exercise and different humidity conditions. J Sport Med Phys Fit. 2015;55:1390–1396.
   PubMed Web of Science ®Google Scholar
• Silva ÉP, Soares BA, Reimberg MM, et al. Heart rate recovery in asthmatic children and adolescents after clinical field test. BMC Pulm Med. 2021;21(1):61. doi: 10.1186/s12890-020-01355-9
   PubMed Web of Science ®Google Scholar
• Gomes ÉLFD, Sampaio LMM, Costa IP, et al. Analysis of autonomic modulation during maximal and submaximal work rate and functional capacity in asthmatic children. J Asthma. 2013;50(6):613–618. doi: 10.3109/02770903.2013.793707
   PubMed Web of Science ®Google Scholar
• Cassol VE, Trevisan ME, de Moraes EZC, et al. Broncoespasmo induzido pelo exercício em crianças e adolescentes com diagnóstico de asma. J Bras Pneumol. 2004;30(2):102–108. doi: 10.1590/S1806-37132004000200005
   Google Scholar
• Aggarwal B, Mulgirigama A, Berend N. Exercise-induced bronchoconstriction: prevalence, pathophysiology, patient impact, diagnosis and management. NPJ Prim Care Respir Med. 2018;28(1):1–8. doi: 10.1038/s41533-018-0098-2
   PubMedGoogle Scholar
• GINA. Global initiative for asthma (GINA). [Cited 2023 Aug 24]. Available from: http://www.ginasthma.org. 2018;
   Google Scholar
• Roxo JPF, Ponte EV, Ramos DCB, et al. Validação do Teste de Controle da Asma em português para uso no Brasil: validation for use in Brazil. J Bras Pneumol. 2010;36(2):159–166. doi: 10.1590/S1806-37132010000200002
   PubMed Web of Science ®Google Scholar
• Pereira C. Espirometria. J Pneumol. 2002;28:S1–S82.
   Google Scholar
• Miller MR. Standardisation of spirometry. Eur Respir J. 2005;26(2):319–338. doi: 10.1183/09031936.05.00034805
   PubMed Web of Science ®Google Scholar
• Giles D, Draper N, Neil W. Validity of the Polar V800 heart rate monitor to measure RR intervals at rest. Eur J Appl Physiol. 2016;116(3):563–571. doi: 10.1007/s00421-015-3303-9
   PubMed Web of Science ®Google Scholar
• Caminal P, Sola F, Gomis P, et al. Validity of the Polar V800 monitor for measuring heart rate variability in mountain running route conditions. Eur J Appl Physiol. 2018;118(3):669–677. doi: 10.1007/s00421-018-3808-0
   PubMed Web of Science ®Google Scholar
• Hernando D, Garatachea N, Almeida R, et al. Validation of heart rate monitor Polar RS800 for heart rate variability analysis during exercise. J Strength Cond Res. 2018;32(3):716–725. doi: 10.1519/JSC.0000000000001662
   PubMed Web of Science ®Google Scholar
• Farah BQ, de Lima AHR A, Cavalcante BR, et al. Intra-individuals and inter- and intra-observer reliability of short-term heart rate variability in adolescents. Clin Physiol Funct Imaging. 2016;36:33–39. doi: 10.1111/cpf.12190
   PubMed Web of Science ®Google Scholar
• Silva CC, Bertollo M, Reichert FF, et al. Reliability of heart rate variability in children: influence of sex and body position during data collection. Pediatr Exerc Sci. 2017;29(2):228–236. doi: 10.1123/pes.2016-0085
   PubMed Web of Science ®Google Scholar
• Malik M, Bigger JT, Camm AJ. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task force of the European society of cardiology and the North American society of pacing and electrophysiology. Eur Hear J. 1996;17(3):354–381. doi: 10.1093/oxfordjournals.eurheartj.a014868
   PubMed Web of Science ®Google Scholar
• Peçanha T, Bartels R, Brito LC, et al. Methods of assessment of the post-exercise cardiac autonomic recovery: a methodological review. Int J Cardiol. 2017;227:795–802. doi: 10.1016/j.ijcard.2016.10.057
   PubMed Web of Science ®Google Scholar
• Barreto M, Zambardi R, Villa MP. Exhaled nitric oxide and other exhaled biomarkers in bronchial challenge with exercise in asthmatic children: current knowledge. Paediatr Respir Rev. 2015;16(1):68–74. doi: 10.1016/j.prrv.2013.11.006
   PubMed Web of Science ®Google Scholar
• Canning BJ. Reflex regulation of airway smooth muscle tone. J Appl Physiol. 2006;101(3):971–985. doi: 10.1152/japplphysiol.00313.2006
   PubMed Web of Science ®Google Scholar
• Terada A, Fujisawa T, Togashi K, et al. Exhaled nitric oxide decreases during exercise-induced bronchoconstriction in children with asthma. Am J Respir Crit Care Med. 2001;164(10):1879–1884. doi: 10.1164/ajrccm.164.10.2009105
   PubMed Web of Science ®Google Scholar
• Ward JK, Belvisi MG, Fox AJ, et al. Modulation of cholinergic neural bronchoconstriction by endogenous nitric oxide and vasoactive intestinal peptide in human airways in vitro. J Clin Invest. 1993;92(2):736–742. doi: 10.1172/JCI116644
   PubMed Web of Science ®Google Scholar
• Pichon A, de Bisschop C, Diaz V, et al. Parasympathetic airway response and heart rate variability before and at the end of methacholine challenge. Chest. 2005;127(1):23–29. doi: 10.1378/chest.127.1.23
   PubMed Web of Science ®Google Scholar
• Holley AB, Cohee B, Walter RJ, et al. Eucapnic voluntary hyperventilation is superior to methacholine challenge testing for detecting airway hyperreactivity in nonathletes. J Asthma. 2012;49(6):614–619. doi: 10.3109/02770903.2012.697955
   PubMed Web of Science ®Google Scholar
• Henriksen AH, Tveit KH, Holmen TL, et al. A study of the association between exercise-induced wheeze and exercise versus methacholine-induced bronchoconstriction in adolescents. Pediatr Allergy Immunol. 2002;13(3):203–208. doi: 10.1034/j.1399-3038.2002.01034.x
   PubMed Web of Science ®Google Scholar
• Eisenberg SR, Jelalian E, Farrow M, et al. Perceptions of asthma and exercise, and associations with weight status and asthma morbidity in Urban children. Acad Pediatr. 2020;20(1):55–62. doi: 10.1016/j.acap.2019.07.001
   PubMed Web of Science ®Google Scholar