Is there still a role for treatment with β-adrenoceptor antagonists in post-myocardial infarction patients with well-preserved left ventricular systolic function?

References

• ACC/AHA Writing Committee. 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction. Circulation 2007;116:e148–e304.
   Google Scholar
• Peter T, Norris RM, Clarke ED, Heng MK, Singh BN, Williams B, et al. Reduction of enzyme levels by propranolol after myocardial infarction. Circulation 1978; 65: 1091–5
   Google Scholar
• Roberts R, Croft C, Gold HC, Hartwell TD, Jaffe AS, Muller JE, et al. Effect of propranolol on myocardial infarct size in a double-blinded multicentre trial. N Engl J Med. 1984; 311: 218–55
   PubMed Web of Science ®Google Scholar
• Hjalmarson A. Effects of beta blockade on sudden cardiac death during acute myocardial infarction. Am J Cardiol 1997; 80: 35J–9J
   Google Scholar
• Wolf SC, Sauter G, Preyer M, Poerner T, Kempf VA, Risler T, et al. Infulence of nebivolol and metoprotol on inflammatory mediators in human coronary endothelial or smooth muscle cells. Effects on neointima formation after balloon denudation in caroted arteries of rats treated with nebivolol. Cell Phyiol Biochem. 2007; 19: 129–36
   PubMed Web of Science ®Google Scholar
• Kern MJ, Ganz P, Horowitz JD, Gaspar J, Barry WH, Lorell BH, et al. Potentiation of coronary vasoconstriction by beta-adrenergic blockade in patients with coronary artery disease. Circulation 1983; 67: 1178–85
   PubMed Web of Science ®Google Scholar
• The Norwegian Multicenter Study Group. Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction. N Engl J Med. 1981;304:801–7.
   PubMed Web of Science ®Google Scholar
• Hjalmarson A, Herlitz J, Holmberg S, Ryden L, Swedberg K, Vedin A, et al. The Goteborg metoprolol trial. Effects on mortality and morbidity in acute myocardial infarction. Circulation 1983; 67: 126–32
   Google Scholar
• β-Blocker Heart Attack Trial Research Group. A randomised trial of propranolol in patients with acute myocardial infarction. 1. Mortality Results. JAMA 1982;247:1707–14.
   PubMed Web of Science ®Google Scholar
• The MIAMI trial Research Group. Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial. Eur Heart J. 1985;6:199–226.
   PubMed Web of Science ®Google Scholar
• ISIS-1 Collaborative Group. Randomised trial of intravenous atenolol among 16027 cases of suspected acute myocardial infarction. ISIS-1. Lancet 1986;2:57–65.
   PubMed Web of Science ®Google Scholar
• Viscoli CM, Horwitz RI, Singer BH. blockers after myocardial infarction: influence of first-year clinical course on long-term effectiveness. Ann Int Med. 1993; 118: 99–105
   PubMed Web of Science ®Google Scholar
• Georghiade M, Schultz L, Tilley B, Kao W, Goldstein S. Effects of propranolol in non-Q-wave acute myocardial infarction in the Beta Blocker Heart Attack Trial. Am J Cardiol. 1990; 66: 129–33
   PubMedGoogle Scholar
• HINT Research Group. Early treatment of unstable angina in the coronary care unit: A randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with Nifedipine or metoprolol or both. Br Heart J. 1986;56:400–13.
   PubMedGoogle Scholar
• Goldman L, Sia STB, Cook EF, Rutherford JD, Weinstein MC. Cost and effectiveness of routine therapy with long-term beta-adrenergic antagonists after acute myocardial infarction. N Eng J Med. 1988; 319: 152–7
   PubMed Web of Science ®Google Scholar
• Roberts R, Rogets WJ, Mueller HS, Lambrew CT, Diver DJ, Smith HC, et al. Immediate versus delayed ß-blockade following thrombosis in patients with acute myocardial infarction. Results of the TIMI II-B study. Circulation 1991; 83: 422–37
   PubMed Web of Science ®Google Scholar
• COMMIT Collaborative group: Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet 2005;366:1622–32.
   PubMedGoogle Scholar
• Dargie HJ. Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: The CAPRICORN randomised trial. Lancet 2001; 357: 1385–90
   PubMed Web of Science ®Google Scholar