138
Views
8
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis

, , , , , , & show all
Pages 233-240 | Published online: 10 Jul 2009

References

  • Simpson E. P., Yen A. A., Appel S. H. Oxidative stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis. Curr Opin Rheumatol 2003; 15: 730–6
  • Bowling A. C., Schulz J. B., Brown R. H., Jr., Beal M. F. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J Neurochem 1993; 61: 2322–5
  • Shibata N., Nagai R., Uchida K., Horiuchi S., Yamada S., Hirano A., et al. Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 2001; 917: 97–104
  • Ferrante R. J., Browne S. E., Shinobu L. A., Bowling A. C., Baik M. J., MacGarvey U., et al. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem 1997; 69: 2064–74
  • Oteiza P. I., Uchitel O. D., Carrasquedo F., Dubrovski A. L., Roma J. C., Fraga C. G. Evaluation of antioxidants, protein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients. Neurochem Res 1997; 22: 535–9
  • Bogdanov M., Brown R. H., Matson W., Smart R., Hayden D., O'Donnell H., et al. Increased oxidative damage to DNA in ALS patients. Free Radic Biol Med 2000; 29: 652–8
  • Cashman J. R. Human flavin‐containing mono‐oxygenase: substrate specificity and role in drug metabolism. Curr Drug Metab 2000; 1: 181–91
  • Phillips I. R., Dolphin C. T., Clair P., Hadley M. R., Hutt A. J., McCombie R. R., et al. The molecular biology of the flavin‐containing monooxygenases of man. Chem Biol Interact 1995; 96: 17–32
  • Hernandez D., Janmohamed A., Chandan P., Phillips I. R., Shephard E. A. Organization and evolution of the flavin‐containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters. Pharmacogenetics 2004; 14: 117–30
  • Janmohamed A., Hernandez D., Phillips I. R., Shephard E. A. Cell‐, tissue‐, sex‐ and developmental stage‐specific expression of mouse flavin‐containing monooxygenases (Fmos). Biochem Pharmacol 2004; 68: 73–83
  • Bhamre S., Bhagwat S. V., Shankar S. K., Boyd M. R., Ravindranath V. Flavin‐containing monooxygenase mediated metabolism of psychoactive drugs by human brain microsomes. Brain Res 1995; 672: 276–80
  • Bhagwat S. V., Bhamre S., Boyd M. R., Ravindranath V. Cerebral metabolism of imipramine and a purified flavin‐containing monooxygenase from human brain. Neuropsychopharmacology 1996; 15: 133–42
  • Bhamre S., Ravindranath V. Presence of flavin‐containing monooxygenase in rat brain. Biochem Pharmacol 1991; 42: 442–4
  • Suh J. K., Poulsen L. L., Ziegler D. M., Robertus J. D. Redox regulation of yeast flavin‐containing monooxygenase. Arch Biochem Biophys 2000; 381: 317–22
  • Suh J. K., Poulsen L. L., Ziegler D. M., Robertus J. D. Yeast flavin‐containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum. Proc Natl Acad Sci. USA 1999; 96: 2687–91
  • Suh J. K., Robertus J. D. Yeast flavin‐containing monooxygenase is induced by the unfolded protein response. Proc Natl Acad Sci. USA 2000; 97: 121–6
  • Bains J. S., Shaw C. A. Neurodegenerative disorders in humans: the role of glutathione in oxidative stress‐mediated neuronal death. Brain Res Brain Res Rev 1997; 25: 335–58
  • Tohgi H., Abe T., Yamazaki K., Murata T., Ishizaki E., Isobe C. Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis. Neurosci Lett 1999; 260: 204–6
  • Malaspina A., Kaushik N., de Belleroche J. Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J Neurochem 2001; 77: 132–45
  • Malaspina A., de Belleroche J. Spinal cord molecular profiling provides a better understanding of amyotrophic lateral sclerosis pathogenesis. Brain Res Res Rev 2004; 45: 213–29
  • Dolphin C. T., Riley J. H., Smith R. L., Shephard E. A., Phillips I. R. Structural organization of the human flavin‐containing monooxygenase 3 gene (FMO3), the favoured candidate for fish‐odour syndrome, determined directly from genomic DNA. Genomics 1997; 46: 260–7
  • Dolphin C. T., Beckett D. J., Janmohamed A., Cullingford T. E., Smith R. L., Shephard E. A., et al. The flavin‐containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, non‐functional protein. J Biol Chem 1998; 273: 30599–607
  • Krueger S. K., Williams D. E., Yueh M. F., Martin S. R., Hines R. N., Raucy J. L., et al. Genetic polymorphisms of flavin‐containing monooxygenase (FMO). Drug Metab Rev 2002; 34: 523–32
  • Krueger S. K., Williams D. E. Mammalian flavin‐containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism. Pharmacol Ther 2005; 106: 357–87
  • Hines R. N., Luo Z., Hopp K. A., Cabacungan E. T., Koukouritaki S. B., McCarver D. G. Genetic variability at the human FMO1 locus: significance of a basal promoter yin yang 1 element polymorphism (FMO1*6). J Pharmacol Exp Ther 2003; 306: 1210–8, Epub 2003, June 26
  • Lahiri D. K., Bye S., Nurnberger J. I., Jr., Hodes M. E., Crisp M. A non‐organic and non‐enzymatic extraction method gives higher yields of genomic DNA from whole‐blood samples than do nine other methods tested. J Biochem Biophys Methods 1992; 25: 193–205
  • Brooks B. R., Miller R. G., Swash M., Munsat T. L., World Federation of Neurology Research Group on Motor Neuron Diseases. El Escorial revisited: revisited criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1: 293–9
  • Terwilliger J. D., Ott J., editors. Handbook of Human Genetic Linkage. Johns Hopkins University Press, Baltimore 1994
  • Gingerich T. J., Feige J. J., LaMarre J. AU‐rich elements and the control of gene expression through regulated mRNA stability. Anim Health Res Rev 2004; 5: 49–63
  • Conne B., Stutz A., Vassalli J. D. The 3' untranslated region of messenger RNA: a molecular 'hotspot' for pathology?. Nat Med 2000; 6: 637–41
  • van Landeghem G. F., Tabatabaie P., Beckman G., Beckman L., Andersen P. M. Manganese‐containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease. Eur J Neurol 1999; 6: 639–44
  • Falls J. G., Ryu D. Y., Cao Y., Levi P. E., Hodgson E. Regulation of mouse liver flavin‐containing monooxygenases 1 and 3 by sex steroids. Arch Biochem Biophys 1997; 342: 212–23
  • Zhang A. Q., Mitchell S. C., Smith R. L. Exacerbation of symptoms of fish‐odour syndrome during menstruation. Lancet 1996; 348: 1740–1
  • Zhang J., Cashman J. R. Quantitative analysis of FMO gene mRNA levels in human tissues. Drug Metab Dispos 2006; 34: 19–26
  • Mayeux R. Mapping the new frontier: complex genetic disorders. J Clin Invest 2005; 115: 1404–7

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.