Nanoparticles as potential clinical therapeutic agents in Alzheimer’s disease: focus on selenium nanoparticles

References

• Song B, Zhang Y, Liu J, et al. Is neurotoxicity of metallic nanoparticles the cascades of oxidative stress? Nanoscale Res Lett. 2016;11:291.
   PubMed Web of Science ®Google Scholar
• Parveen A, Sh R, Sushma, et al. Intranasal exposure to silica nanoparticles induce alterations in pro-inflammatory environment of rat brain, involvement of oxidative stress. Toxicol Ind Health. 2017;33(2):119–132.
   PubMed Web of Science ®Google Scholar
• Zhang R, Niu YJ, Li YW, et al. Acute toxicity study of the interaction between titanium dioxide nanoparticles and lead acetate in mice. Environ Toxicol Pharmacol. 2010;30:52–60.
   PubMed Web of Science ®Google Scholar
• Shinohara N, Oshima Y, Kobayashi T, et al. Pulmonary clearance kinetics and extrapulmonary translocation of seven titanium dioxide nano- and submicron materials following intratracheal administration in rats. Nanotoxicology. 2015;9(8):1050–1058.
   PubMed Web of Science ®Google Scholar
• Hritcu L, Stefan M, Ursu L, et al. Exposure to silver nanoparticles induces oxidative stress and memory deficits in laboratory rats. Cen Euro J Biol. 2011;6(4):497–509.
   Google Scholar
• Feng XL, Chen AJ, Zhang YL, et al. Central nervous system toxicity of metallic nanoparticles. Int J Nanomed. 2015;10:4321–4340.
   PubMed Web of Science ®Google Scholar
• Wang JY, Rahman MF, Duhart HM, et al. Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles. Neurotoxicology. 2009;30(6):926–933.
   PubMed Web of Science ®Google Scholar
• Rahman MF, Wang J, Patterson TA, et al. Expression of genes related to oxidative stress in the mouse brain after exposure to silver-25 nanoparticles. Toxicol Lett. 2009;187:15–21.
   PubMed Web of Science ®Google Scholar
• Jeon YM, Park SK, Lee MY. Toxicoproteomic identification of TiO2 nanoparticle-induced protein expression changes in mouse brain. Anim Cells Syst. 2011;15(2):107–114.
   Web of Science ®Google Scholar
• Vedagiri A, Thangarajan S. Mitigating effect of chrysin loaded solid lipid nanoparticles against amyloid β25-35 induced oxidative stress in rat hippocampal region, an efficient formulation approach for Alzheimer’s disease. Neuropeptides. 2016;58:111–125.
   PubMed Web of Science ®Google Scholar
• Halliwell B. Oxidative stress and neurodegeneration, where are we now? J Neurochem. 2006;97(6):1634–1658.
   PubMed Web of Science ®Google Scholar
• Nazıroğlu M. Role of selenium on calcium signaling and oxidative stress-induced molecular pathways in epilepsy. Neurochem Res. 2009;34:2181–2191.
   PubMed Web of Science ®Google Scholar
• Nogueira CW, Rocha JB. Toxicology and pharmacology of selenium, emphasis on synthetic organoselenium compounds. Arch Toxicol. 2011;85(11):1313–1359.
   PubMed Web of Science ®Google Scholar
• Weekley CM, Harris HH. Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease. Chem Soc Rev. 2013;42:8870–8894.
   PubMed Web of Science ®Google Scholar
• Nazıroğlu M. TRPM2 cation channels, oxidative stress and neurological diseases, where are we now? Neurochem Res. 2011;36:355–366.
   PubMed Web of Science ®Google Scholar
• Nazıroğlu M, Demirdaş A. Psychiatric disorders and TRP channels, focus on psychotropic drugs. Curr Neuropharmacol. 2015;13(2):248–257.
   PubMed Web of Science ®Google Scholar
• Ceballos-Picot I, Merad-Boudia M, Nicole A, et al. Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer’s type – place of the extracellular glutathione peroxidase. Free Radic Biol Med. 1996;20(4):579–587.
   PubMed Web of Science ®Google Scholar
• Vural H, Demirin H, Kara Y, et al. Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer’s disease. J Trace Elem Med Biol. 2010;24(3):169–173.
   PubMed Web of Science ®Google Scholar
• Rita Cardoso B, Silva Bandeira V, Jacob-Filho W, et al. Selenium status in elderly: relation to cognitive decline. J Trace Elem Med Biol. 2014;28(4):422–426.
   Web of Science ®Google Scholar
• Koç ER, Ilhan A, Aytürk Z, et al. A comparison of hair and serum trace elements in patients with Alzheimer disease and healthy participants. Turk J Med Sci. 2015;45:1034–1039.
   PubMed Web of Science ®Google Scholar
• Kosik KS. Alzheimer’s disease, a cell biological perspective. Science. 1992;256:780–783.
   PubMed Web of Science ®Google Scholar
• Balaban H, Nazıroğlu M, Demirci K, et al. The protective role of selenium on scopolamine-induced memory impairment, oxidative stress, and apoptosis in aged rats, the involvement of TRPM2 and TRPV1 channels. Mol Neurobiol. 2017;54:2852–2868.
   PubMed Web of Science ®Google Scholar
• Schweizer U, Bräuer AU, Köhrle J, et al. Selenium and brain function, a poorly recognized liaison. Brain Res Brain Res Rev. 2004;45:164–178.
   PubMed Web of Science ®Google Scholar
• Zhang J, Gao X, Zhang L, et al. Biological effects of a nano red elemental selenium. BioFactors. 2001;15:27–38.
   PubMed Web of Science ®Google Scholar
• Fernandes AP, Gandin V. Selenium compounds as therapeutic agents in cancer. Biochim Biophys Acta. 2015;1850(8):1642–1660.
   PubMed Web of Science ®Google Scholar
• Busquets MA, Sabaté R, Estelrich J. Potential applications of magnetic particles to detect and treat Alzheimer’s disease. Nanoscale Res Lett. 2014;9(1):538.
   PubMed Web of Science ®Google Scholar
• Gupta S, Babu P, Surolia A. Biphenyl ethers conjugated CdSe/ZnS core/shell quantum dots and interpretation of the mechanism of amyloid fibril disruption. Biomaterials. 2010;31(26):6809–6822.
   PubMed Web of Science ®Google Scholar
• Zhang J, Zhou X, Yu Q, et al. Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity. Appl Mater Interfaces. 2014;6:8475–8487.
   PubMed Web of Science ®Google Scholar
• Yin T, Yang L, Liu Y, et al. Sialic acid (SA)-modified selenium nanoparticles coated with a high blood-brain barrier permeability peptide-B6 peptide for potential use in Alzheimer’s disease. Acta Biomater. 2015;25:172–183.
   PubMed Web of Science ®Google Scholar
• Wang Z, Wang Y, Li W, et al. Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer’s disease. ACS Chem Neurosci. 2014;5:952–962.
   PubMed Web of Science ®Google Scholar
• Kahya MC, Nazıroğlu M, Çiğ B. Selenium reduces mobile phone (900 MHz)-induced oxidative stress, mitochondrial function, and apoptosis in breast cancer cells. Biol Trace Elem Res. 2014;160:285–293.
   PubMed Web of Science ®Google Scholar
• Heusinkveld HJ, Wahle T, Campbell A, et al. Neurodegenerative and neurological disorders by small inhaled particles. Neurotoxicology. 2016;56:94–106.
   PubMed Web of Science ®Google Scholar
• Nazıroğlu M. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose. Neurochem Res. 2007;32:1990–2001.
   PubMed Web of Science ®Google Scholar
• Bush AI, Pettingell WH, Multhaup G, et al. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science. 1994;265:1464–1467.
   PubMed Web of Science ®Google Scholar
• Yamin G, Ono K, Inayathullah M, et al. Amyloid-protein assembly as a therapeutic target of Alzheimer’s disease. Curr Pharm Des. 2008;14:3231–3246.
   PubMed Web of Science ®Google Scholar
• Ajith TA, Padmajanair G. Mitochondrial pharmaceutics, a new therapeutic strategy to ameliorate oxidative stress in Alzheimer’s disease. Curr Aging Sci. 2015;8:235–240.
   PubMedGoogle Scholar
• Tran MH, Yamada K, Olariu A, et al. Amyloid beta peptide induces nitric oxide production in rat hippocampus, association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors. Faseb J. 2001;15:1407–1409.
   PubMed Web of Science ®Google Scholar
• Choi J, Malakowsky CA, Talent JM, et al. Anti-apoptotic proteins are oxidized by Abeta25-35 in Alzheimer’s fibroblasts. Biochim Biophys Acta. 2003;1637:135–141.
   PubMed Web of Science ®Google Scholar
• Zhao QF, Yu JT, Tan L. S-nitrosylation in Alzheimer’s disease. Mol Neurobiol. 2015;51:268–280.
   PubMed Web of Science ®Google Scholar
• Durazo SA, Kompella UB. Functionalized nanosystems for targeted mitochondrial delivery. Mitochondrion. 2012;12:190–201.
   PubMed Web of Science ®Google Scholar
• Bonda DJ, Wang X, Perry G, et al. Oxidative stress in Alzheimer disease, a possibility for prevention. Neuropharmacology. 2010;59:290–294.
   PubMed Web of Science ®Google Scholar
• Jazvinšćak JM, Hof PR, Šimić G. Ceramides in Alzheimer’s disease, key mediators of neuronal apoptosis induced by oxidative stress and Aβ accumulation. Oxid Med Cell Longev. 2015;2015:346783.
   PubMedGoogle Scholar
• Hayes JD, Flanagan JU, Jowsey IR. Glutathione transferases. Annu Rev Pharmacol Toxicol. 2005;45:51–88.
   PubMed Web of Science ®Google Scholar
• Loef M, Schrauzer GN, Selenium WH. Alzheimer’s disease, a systematic review. J Alzheimers Dis. 2011;26:81–104.
   PubMed Web of Science ®Google Scholar
• González-Domínguez R, García-Barrera T, Gómez-Ariza JL. Homeostasis of metals in the progression of Alzheimer’s disease. Biometals. 2014;27:539–549.
   PubMed Web of Science ®Google Scholar
• Ishrat T, Parveen K, Khan MM, et al. Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer’s type. Brain Res. 2009;1281:117–127.
   PubMed Web of Science ®Google Scholar
• Krishnan S, Rani P. Evaluation of selenium, redox status and their association with plasma amyloid/tau in Alzheimer’s disease. Biol Trace Elem Res. 2014;158:158–165.
   PubMed Web of Science ®Google Scholar
• Kumar VS, Gopalakrishnan A, Nazıroğlu M, et al. Calcium ion – the key player in cerebral ischemia. Curr Med Chem. 2014;21:2065–2075.
   PubMed Web of Science ®Google Scholar
• Yürüker V, Nazıroğlu M, Şenol N. Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin, possible involvement of TRPM2 channels. Metab Brain Dis. 2015;30:223–231.
   PubMed Web of Science ®Google Scholar
• Ashraf GM, Tabrez S, Jabir NR, et al. An overview on global trends in nanotechnological approaches for Alzheimer therapy. Curr Drug Metab. 2015;16(8):719–727.
   PubMed Web of Science ®Google Scholar
• Soursou G, Alexiou A, Ashraf GM, et al. Applications of nanotechnology in diagnostics and therapeutics of Alzheimer’s and Parkinson’s disease. Curr Drug Metab. 2015;16(8):705–712.
   PubMed Web of Science ®Google Scholar
• Kamal MA. Global trends in nanotechnological approaches for various health issues – volume II. Curr Drug Metab. 2015;16(8):598–601.
   PubMed Web of Science ®Google Scholar
• Ali A, Sheikh IA, Mirza Z, et al. Application of proteomic tools in modern nanotechnological approaches towards effective management of neurodegenerative disorders. Curr Drug Metab. 2015;16(5):376–388.
   PubMed Web of Science ®Google Scholar
• Ahmad MZ, Ahmad J, Amin S, et al. Role of nanomedicines in delivery of anti-acetylcholinesterase compounds to the brain in Alzheimer’s disease. CNS Neurol Disord Drug Targets. 2014;13(8):1315–1324.
   PubMed Web of Science ®Google Scholar
• Alam Q, ZubairAlam M, Karim S, et al. A nanotechnological approach to the management of Alzheimer disease and type 2 diabetes. CNS Neurol Disord Drug Targets. 2014;13(3):478–486.
   PubMed Web of Science ®Google Scholar
• Bao P, Chen Z, Tai RZ, et al. Selenite-induced toxicity in cancer cells is mediated by metabolic generation of endogenous selenium nanoparticles. J Proteome Res. 2015;14:1127–1136.
   PubMed Web of Science ®Google Scholar
• Carrasco C, Rodríguez AB, Pariente JA. Melatonin as a stabilizer of mitochondrial function, role in diseases and aging. Turk J Biol. 2015;39:822–831.
   Web of Science ®Google Scholar
• Rayman MP. The importance of selenium to human health. Lancet. 2000;356:233–241.
   PubMed Web of Science ®Google Scholar
• Suzuki KT, Kurasaki K, Suzuki N. Selenocysteine beta-lyase and methylselenol demethylase in the metabolism of Se-methylated selenocompounds into selenide. Biochim Biophys Acta. 2007;1770:1053–1061.
   PubMed Web of Science ®Google Scholar
• Weekley CM, Aitken JB, Vogt S, et al. Metabolism of selenite in human lung cancer cells, X-ray absorption and fluorescence studies. J Am Chem Soc. 2011;133:18272–18279.
   PubMed Web of Science ®Google Scholar
• Verma A, Stellacci F. Effect of surface properties on nanoparticle-cell interactions. Small. 2010;6:12–21.
   PubMed Web of Science ®Google Scholar
• Huang B, Zhang J, Hou J, et al. Free radical scavenging efficiency of nano-Se in vitro. Free Radic Biol Med. 2003;35:805–813.
   PubMed Web of Science ®Google Scholar
• Zhang J, Wang H, Bao Y, et al. Nano red elemental selenium has no size effect in the induction of seleno-enzymes in both cultured cells and mice. Life Sci. 2004;75:237–244.
   PubMed Web of Science ®Google Scholar
• Qi L, Xu Z, Chen M. In vitro and in vivo suppression of hepatocellular carcinoma growth by chitosan nanoparticles. Eur J Cancer. 2007;43:184–193.
   PubMed Web of Science ®Google Scholar
• Peng D, Zhang J, Liu Q, et al. Size effect of elemental selenium nanoparticles (nano-Se) at supranutritional levels on selenium accumulation and glutathione S-transferase activity. Inorg Biochem. 2007;101:1457–1463.
   PubMed Web of Science ®Google Scholar
• Amin KA, Hashem KS, Alshehri FS, et al. Antioxidant and hepatoprotective efficiency of selenium nanoparticles against acetaminophen-induced hepatic damage. Biol Trace Elem Res. 2017;175:136–145.
   PubMed Web of Science ®Google Scholar
• Ze Y, Hu R, Wang X, et al. Neurotoxicity and gene expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles. J Biomed Mater Res Part A. 2014;102(2):470–478.
   PubMed Web of Science ®Google Scholar
• Choi J, Zheng QD, Katz HE, et al. Silica-based nanoparticle uptake and cellular response by primary microglia. Environ Health Perspect. 2010;118:589–595.
   PubMed Web of Science ®Google Scholar
• Li CH, Shen CC, Cheng YW, et al. Organ biodistribution, clearance, and genotoxicity of orally administered zinc oxide nanoparticles in mice. Nanotoxicology. 2012;6:746–756.
   PubMed Web of Science ®Google Scholar
• Tian L, Lin BC, Wu L, et al. Neurotoxicity induced by zinc oxide nanoparticles, age-related differences and interaction. Sci Rep. 2015;5:12.
   Web of Science ®Google Scholar
• Dziendzikowska K, Gromadzka-Ostrowska J, Lankoff A, et al. Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats. J Appl Toxicol. 2012;32:920–928.
   PubMed Web of Science ®Google Scholar
• Yang Y, Mao Z, Huang W, et al. Redox enzyme-mimicking activities of CeO(2) nanostructures: intrinsic influence of exposed facets. Sci Rep. 2016;6:35344.
   PubMed Web of Science ®Google Scholar
• Dowding JM, Song W, Bossy K, et al. Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death. Cell Death Differ. 2014;21(10):1622–1632.
   PubMed Web of Science ®Google Scholar
• Guan Y, Gao N, Ren J, et al. Rationally designed CeNP@MnMoS4 core-shell nanoparticles for modulating multiple facets of Alzheimer’s disease. Chem Eur J. 2016;22:14523–14526.
   PubMed Web of Science ®Google Scholar
• Guan Y, Li M, Dong K, et al. Ceria/POMs hybrid nanoparticles as a mimicking metallopeptidase for treatment of neurotoxicity of amyloid-β peptide. Biomaterials. 2016;98:92–102.
   PubMed Web of Science ®Google Scholar
• Du X, Wang C, Liu Q. Potential roles of selenium and selenoproteins in the prevention of Alzheimer’s disease. Curr Top Med Chem. 2016;16:835–848.
   PubMed Web of Science ®Google Scholar
• Huang CL, Hsiao IL, Lin HC, et al. Silver nanoparticles’ effect on gene expression of inflammatory and neurodegenerative responses in mouse brain neural cells. Environ Res. 2015;136:253–263.
   PubMed Web of Science ®Google Scholar
• Tang M, Wang M, Xing T, et al. Mechanisms of unmodified CdSe quantum dot-induced elevation of cytoplasmic calcium levels in primary cultures of rat hippocampal neurons. Biomaterials. 2008;29(33):4383–4391.
   PubMed Web of Science ®Google Scholar
• Pecze L, Blum W, Schwaller B. Routes of Ca2+ shuttling during Ca2+ oscillations: focus on the role of mitochondrial Ca2+ handling and cytosolic Ca2+ buffers. J Biol Chem. 2015;290(47):28214–28230.
   PubMed Web of Science ®Google Scholar
• Pecze L, Blum W, Henzi T, et al. Endogenous TRPV1 stimulation leads to the activation of the inositol phospholipid pathway necessary for sustained Ca(2+) oscillations. Biochim Biophys Acta. 2016;1863(12):2905–2915.
   PubMed Web of Science ®Google Scholar
• Pecze L, Winter Z, Jósvay K, et al. Divalent heavy metal cations block the TRPV1 Ca(2+) channel. Biol Trace Elem Res. 2013;151(3):451–461.
   PubMed Web of Science ®Google Scholar
• Pecze L, Jósvay K, Blum W, et al. Activation of endogenous TRPV1 fails to induce overstimulation-based cytotoxicity in breast and prostate cancer cells but not in pain-sensing neurons. Biochim Biophys Acta. 2016;1863(8):2054–2064.
   PubMed Web of Science ®Google Scholar
• Kahya MC, Nazıroğlu M, Övey İS. Modulation of diabetes-induced oxidative stress, apoptosis, and Ca2+ entry through TRPM2 and TRPV1 channels in dorsal root ganglion and hippocampus of diabetic rats by melatonin and selenium. Mol Neurobiol. 2017;54:2345–2360.
   PubMed Web of Science ®Google Scholar
• Nel A, Xia T, Mädler L, et al. Toxic potential of materials at the nano level. Science. 2006;311(5761):622–627.
   PubMed Web of Science ®Google Scholar
• Juillerat-Jeanneret L. The targeted delivery of cancer drugs across the blood-brain barrier, chemical modifications of drugs or drug-nanoparticles? Drug Discov Today. 2008;13:1099–1106.
   PubMed Web of Science ®Google Scholar
• Halamoda Kenzaoui B, Chapuis Bernasconi C, Guney-Ayra S, et al. Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells. Biochem J. 2012;441:813–821.
   PubMed Web of Science ®Google Scholar
• Tang J, Xiong L, Zhou G, et al. Silver nanoparticles crossing through and distribution in the blood-brain barrier in vitro. J Nanosci Nanotechnol. 2010;10(10):6313–6317.
   PubMed Web of Science ®Google Scholar