Guideline recommendations on the pharmacological management of non-specific low back pain in primary care – is there a need to change?

References

• Global Burden of Disease Study C. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800.
   PubMed Web of Science ®Google Scholar
• Hartvigsen J, Hancock MJ, Kongsted A, et al. What low back pain is and why we need to pay attention. Lancet. 2018;391(10137):2356–2367.
   Web of Science ®Google Scholar
• Vasseljen O, Woodhouse A, Bjorngaard JH, et al. Natural course of acute neck and low back pain in the general population: the HUNT study. Pain. 2013;154(8):1237–1244.
   PubMedGoogle Scholar
• Machado GC, Maher CG, Ferreira PH, et al. Can recurrence after an acute episode of low back pain be predicted? Phys Ther. 2017;97(9):889–895.
   PubMed Web of Science ®Google Scholar
• da Silva T, Mills K, Brown BT, et al. Risk of recurrence of low back pain: a systematic review. J Orthop Sports Phys Ther. 2017;47(5):305–313.
   PubMed Web of Science ®Google Scholar
• Meucci RD, Fassa AG, Faria NM. Prevalence of chronic low back pain: systematic review. Rev Saude Publica. 2015;49.
   PubMed Web of Science ®Google Scholar
• Henschke N, Maher CG, Refshauge KM, et al. Prevalence of and screening for serious spinal pathology in patients presenting to primary care settings with acute low back pain. Arthritis Rheum. 2009;60(10):3072–3080.
   PubMed Web of Science ®Google Scholar
• Foster NE, Anema JR, Cherkin D, et al. Prevention and treatment of low back pain: evidence, challenges, and promising directions. Lancet. 2018;391(10137):2368–2383.
   PubMed Web of Science ®Google Scholar
• Williams CM, Maher CG, Hancock MJ, et al. Low back pain and best practice care: A survey of general practice physicians. Arch Intern Med. 2010;170(3):271–277.
   PubMedGoogle Scholar
• Mathieson S, Valenti L, Maher CG, et al. Worsening trends in analgesics recommended for spinal pain in primary care. Eur Spine J. 2018;27(5):1136–1145.
   PubMed Web of Science ®Google Scholar
• Vogt MT, Kwoh CK, Cope DK, et al. Analgesic usage for low back pain: impact on health care costs and service use. Spine (Phila Pa 1976). 2005;30(9):1075–1081.
   PubMed Web of Science ®Google Scholar
• Enthoven WT, Scheele J, Bierma-Zeinstra SM, et al. Analgesic use in older adults with back pain: the BACE study. Pain Med. 2014;15(10):1704–1714.
   PubMed Web of Science ®Google Scholar
• Koes BW, van Tulder M, Lin CW, et al. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. Eur Spine J. 2010;19(12):2075–2094.
   PubMed Web of Science ®Google Scholar
• Disorders QTFoS. Scientific approach to the assessment and management of activity-related spinal disorders. A monograph for clinicians. Report of the quebec task force on spinal disorders. Spine (Phila Pa 1976). 1987;12(7Suppl):S1–59.
   PubMedGoogle Scholar
• NSW Agency for Clinical Innovation. Management of people with acute low back pain: model of care. Vol. 39. Chatswood: NSW Health; 2016.
   Google Scholar
• Van Wambeke P, Desomer A, Ailliet L, et al. Low back pain and radicular pain: assessment and management. Belgian Health Care Knowledge Centre. 2017.
   Google Scholar
• Institute of Health Economics Alberta Canada. Evidence-informed primary care management of low back pain. 2017. Available from: www.ihe.caorwww.topalbertadoctors.org
   Google Scholar
• Stochkendahl MJ, Kjaer P, Hartvigsen J, et al. National clinical guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy. Eur Spine J. 2018;27(1):60–75.
   PubMed Web of Science ®Google Scholar
• Chenot JF, Greitemann B, Kladny B, et al. Non-specific low back pain. Dtsch Arztebl Int. 2017;114(51–52):883–890.
   PubMed Web of Science ®Google Scholar
• Bons SCS, Borg MAJP, Van den Donk M, et al. The revised Dutch College of General Practitioners (NHG) practice guideline on ‘Non-specific Low Back Pain’(in Dutch). Huisarts Wet. 2017;60(2):78–84.
   Google Scholar
• Bernstein IA, Malik Q, Carville S, et al. Low back pain and sciatica: summary of NICE guidance. BMJ. 2017;356:i6748.
   PubMed Web of Science ®Google Scholar
• Qaseem A, Wilt TJ, McLean RM, et al. Clinical guidelines committee of the American College of P. Noninvasive treatments for acute, subacute, and chronic low back pain: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2017;166(7):514–530.
   PubMed Web of Science ®Google Scholar
• Chaparro LE, Furlan AD, Deshpande A, et al. Opioids compared to placebo or other treatments for chronic low-back pain. Cochrane Database Syst Rev. 2013;(8):CD004959.
   PubMed Web of Science ®Google Scholar
• Roelofs PD, Deyo RA, Koes BW, et al. Non-steroidal anti-inflammatory drugs for low back pain. Cochrane Database Syst Rev. 2008;(1):CD000396.
   PubMed Web of Science ®Google Scholar
• Enthoven WT, Roelofs PD, Deyo RA, et al. Non-steroidal anti-inflammatory drugs for chronic low back pain. Cochrane Database Syst Rev. 2016;2:CD012087.
   PubMed Web of Science ®Google Scholar
• Saragiotto BT, Machado GC, Ferreira ML, et al. Paracetamol for low back pain. Cochrane Database Syst Rev. 2016;(6):CD012230.
   PubMed Web of Science ®Google Scholar
• Urquhart DM, Hoving JL, Assendelft WW, et al. Antidepressants for non-specific low back pain. Cochrane Database Syst Rev. 2008;(1):CD001703.
   PubMed Web of Science ®Google Scholar
• van Tulder MW, Touray T, Furlan AD, et al. Muscle relaxants for non-specific low back pain. Cochrane Database Syst Rev. 2003;(2):CD004252.
   PubMedGoogle Scholar
• Abdel Shaheed C, Maher CG, Williams KA, et al. Efficacy, tolerability, and dose-dependent effects of opioid analgesics for low back pain: a systematic review and meta-analysis. JAMA Intern Med. 2016;176(7):958–968.
   PubMed Web of Science ®Google Scholar
• Chou R, Deyo R, Friedly J, et al. Systemic pharmacologic therapies for low back pain: a systematic review for an american college of physicians clinical practice guideline. Ann Intern Med. 2017;166(7):480–492.
   PubMed Web of Science ®Google Scholar
• Shanthanna H, Gilron I, Rajarathinam M, et al. Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials. PLoS Med. 2017;14(8):e1002369.
   PubMed Web of Science ®Google Scholar
• Abdel Shaheed C, Maher CG, Williams KA, et al. Efficacy and tolerability of muscle relaxants for low back pain: systematic review and meta-analysis. Eur J Pain. 2017;21(2):228–237.
   PubMed Web of Science ®Google Scholar
• Machado GC, Maher CG, Ferreira PH, et al. Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials. BMJ. 2015;350:h1225.
   PubMed Web of Science ®Google Scholar
• Machado GC, Maher CG, Ferreira PH, et al. Non-steroidal anti-inflammatory drugs for spinal pain: a systematic review and meta-analysis. Ann Rheum Dis. 2017;76(7):1269–1278.
   PubMed Web of Science ®Google Scholar
• Shea BJ, Reeves BC, Wells G, et al. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ. 2017;358:j4008.
   PubMed Web of Science ®Google Scholar
• Chaparro LE, Furlan AD, Deshpande A, et al. Opioids compared with placebo or other treatments for chronic low back pain: an update of the Cochrane Review. Spine (Phila Pa 1976). 2014;39(7):556–563.
   PubMed Web of Science ®Google Scholar
• Koes BW, Backes D, Bindels PJE. Pharmacotherapy for chronic non-specific low back pain: current and future options. Expert Opin Pharmacother. 2018;19(6):537–545.
   PubMed Web of Science ®Google Scholar
• Deyo RA, Von Korff M, Duhrkoop D. Opioids for low back pain. BMJ. 2015;350:g6380.
   PubMed Web of Science ®Google Scholar
• Vowles KE, McEntee ML, Julnes PS, et al. Rates of opioid misuse, abuse, and addiction in chronic pain: a systematic review and data synthesis. Pain. 2015;156(4):569–576.
   PubMed Web of Science ®Google Scholar
• Walker C, Biasucci LM. Cardiovascular safety of non-steroidal anti-inflammatory drugs revisited. Postgrad Med. 2018;130(1):55–71.
   PubMed Web of Science ®Google Scholar
• Coxib traditional Nsaid Trialists’ Collaboration, Bhala N, Emberson J, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet 2013;382(9894):769–779.
   PubMed Web of Science ®Google Scholar
• Bhatt DL, Scheiman J, Abraham NS, et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of cardiology foundation task force on clinical expert consensus documents. J Am Coll Cardiol. 2008;52(18):1502–1517.
   PubMed Web of Science ®Google Scholar
• Herndon CM, Dankenbring DM. Patient perception and knowledge of acetaminophen in a large family medicine service. J Pain Palliat Care Pharmacother. 2014;28(2):109–116.
   PubMedGoogle Scholar
• Roberts E, Delgado Nunes V, Buckner S, et al. Paracetamol: not as safe as we thought? A systematic literature review of observational studies. Ann Rheum Dis. 2016;75(3):552–559.
   PubMed Web of Science ®Google Scholar
• Bunchorntavakul C, Reddy KR. Acetaminophen (APAP or N-Acetyl-p-Aminophenol) and acute liver failure. Clin Liver Dis. 2018;22(2):325–346.
   PubMed Web of Science ®Google Scholar
• Riediger C, Schuster T, Barlinn K, et al. Adverse effects of antidepressants for chronic pain: a systematic review and meta-analysis. Front Neurol. 2017;8:307.
   PubMed Web of Science ®Google Scholar
• Moore RA, Straube S, Wiffen PJ, et al. Pregabalin for acute and chronic pain in adults. Cochrane Database Syst Rev. 2009;(3):CD007076.
   PubMed Web of Science ®Google Scholar
• Seldenrijk A, Vis R, Henstra M, et al. [Systematic review of the side effects of benzodiazepines]Aandacht voor bijwerkingen van benzodiazepinen is belangrijk: een systematisch overzicht. Ned Tijdschr Geneeskd. 2017;161:D1052.
   PubMedGoogle Scholar
• Maher C, Underwood M, Buchbinder R. Non-specific low back pain. Lancet. 2017;389(10070):736–747.
   PubMed Web of Science ®Google Scholar
• Mistry D, Patel S, Hee SW, et al. Evaluating the quality of subgroup analyses in randomized controlled trials of therapist-delivered interventions for nonspecific low back pain: a systematic review. Spine (Phila Pa 1976). 2014;39(7):618–629.
   PubMed Web of Science ®Google Scholar
• Saragiotto BT, Maher CG, Moseley AM, et al. A systematic review reveals that the credibility of subgroup claims in low back pain trials was low. J Clin Epidemiol. 2016;79:3–9.
   PubMed Web of Science ®Google Scholar
• Hayden JA, Cartwright JL, Riley RD, et al. Chronic Low Back Pain IPDM-AG. Exercise therapy for chronic low back pain: protocol for an individual participant data meta-analysis. Syst Rev. 2012;1:64.
   PubMedGoogle Scholar
• de Zoete A, de Boer MR, van Tulder MW, et al. Rational and design of an individual participant data meta-analysis of spinal manipulative therapy for chronic low back pain-a protocol. Syst Rev. 2017;6(1):21.
   PubMedGoogle Scholar
• Weesie Y, Van Dijk L, Nielen M, et al. Voorschrijven van opioiden in de huisartsenpraktijk [Prescription of opioids in general practice]. 2016. Available from: www.nivel.nl
   Google Scholar
• Foy R, Leaman B, McCrorie C, et al. Prescribed opioids in primary care: cross-sectional and longitudinal analyses of influence of patient and practice characteristics. BMJ Open. 2016;6(5):e010276.
   PubMed Web of Science ®Google Scholar
• Di Iorio D, Henley E, Doughty A. A survey of primary care physician practice patterns and adherence to acute low back problem guidelines. Arch Fam Med. 2000;9(10):1015–1021.
   PubMedGoogle Scholar
• Gonzalez-Urzelai V, Palacio-Elua L, Lopez-de-Munain J. Routine primary care management of acute low back pain: adherence to clinical guidelines. Eur Spine J. 2003;12(6):589–594.
   PubMed Web of Science ®Google Scholar
• Little P, Smith L, Cantrell T, et al. General practitioners’ management of acute back pain: a survey of reported practice compared with clinical guidelines. BMJ. 1996;312(7029):485–488.
   PubMedGoogle Scholar
• Slade SC, Kent P, Patel S, et al. Barriers to primary care clinician adherence to clinical guidelines for the management of low back pain: a systematic review and metasynthesis of qualitative studies. Clin J Pain. 2016;32(9):800–816.
   PubMed Web of Science ®Google Scholar
• Buchbinder R, Gross DP, Werner EL, et al. Understanding the characteristics of effective mass media campaigns for back pain and methodological challenges in evaluating their effects. Spine (Phila Pa 1976). 2008;33(1):74–80.
   PubMed Web of Science ®Google Scholar
• Spoelman WA, Bonten TN, de Waal MW, et al. Effect of an evidence-based website on healthcare usage: an interrupted time-series study. BMJ Open. 2016;6(11):e013166.
   PubMed Web of Science ®Google Scholar
• American Chronic Pain Association. Consumers’ guide practice guidelines for low back pain. 2008. Available from: https://www.theacpa.org/pain-management-tools/resource-guide-to-chronic-pain-treatments/consumer-guidelines-for-low-back-pain/.
   Google Scholar
• NSW Agency for Clinical Innovation. Best practice care for people with acute low back pain. Chatswood: NSW Health; 2017. p. 12.
   Google Scholar