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Review

Prevention of colistin induced nephrotoxicity: a review of preclinical and clinical data

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Pages 1113-1131 | Received 01 Apr 2021, Accepted 17 May 2021, Published online: 09 Jun 2021

References

  • Kumazawa J, Yagisawa M. The history of antibiotics: the Japanese story. J Infect Chemother. 2002;8(2):125–133.
  • Nation RL, Rigatto MHP, Falci DR, et al. Polymyxin acute kidney injury: dosing and other strategies to reduce toxicity. Antibiotics. 2019;8(1):24.
  • Oktan MA, Heybeli C, Ural C, et al. Alpha-lipoic acid alleviates colistin nephrotoxicity in rats. Hum Exp Toxicol. 2021;40(5):761-771.
  • Javan AO, Shokouhi S, Sahraei Z. A review on colistin nephrotoxicity. Eur J Clin Pharmacol. 2015;71(7):801–810.
  • Nation RL, Li J. Polymyxins. In: Grayson ML, Cosgrove SE, Crowe SM, et al, editors. Kucers' The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, 7th ed. Boca Raton, Florida: CRC Press; 2018. p. 1420.
  • MacLaren G, Spelman D Polymyxins: an overview. Up to Date Ed Post TW, UpToDate, Waltham, MA Disponible en Fecha de consulta: https://www.uptodatecom/contents/polymyxins-an-overview. [cited 2020 Oct 10]. 2012;5( 2):2020.
  • Zhang Y, Chi X, Wang Z, et al. Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice. Biomed Pharmacother. 2019;116:108970.
  • Dai C, Wang Y, Sharma G, et al. Polymyxins–curcumin combination antimicrobial therapy: safety implications and efficacy for infection treatment. Antioxidants. 2020;9(6):506.
  • Eljaaly K, Bidell MR, Gandhi RG, et al. Colistin Nephrotoxicity: Meta-Analysis of Randomized Controlled Trials. Open forum infect dis.2021;8(2):ofab026
  • Oliota AF, Penteado ST, Tonin FS, et al. Nephrotoxicity prevalence in patients treated with polymyxins: a systematic review with meta-analysis of observational studies. Diagn Microbiol Infect Dis. 2019;94(1):41–49.
  • Ghlissi Z, Hakim A, Sila A, et al. Evaluation of efficacy of natural astaxanthin and vitamin E in prevention of colistin-induced nephrotoxicity in the rat model. Environ Toxicol Pharmacol. 2014;37(3):960–966.
  • Bader Z, Waheed A, Bakhtiar S, et al. Alpha-tocopherol ameliorates nephrotoxicity associated with the use of colistin in rabbits. Pak J Pharm Sci. 2018;31(2):463–467.
  • Lee S-H, Kim J-S, Ravichandran K, et al. P-glycoprotein induction ameliorates colistin induced nephrotoxicity in cultured human proximal tubular cells. PLoS One. 2015;10(8):e0136075.
  • Sales GTM, Foresto RD. Drug-induced nephrotoxicity. Revista da Associação Médica Brasileira. 2020;66(suppl 1):s82–s90.
  • Sirijatuphat R, Limmahakhun S, Sirivatanauksorn V, et al., Preliminary clinical study of the effect of ascorbic acid on colistin-associated nephrotoxicity. Antimicrob Agents Chemother. 59(6): 3224–3232. 2015.
  • Sivanesan SS, Azad MA, Schneider EK, et al. Gelofusine ameliorates colistin-induced nephrotoxicity. Antimicrob Agents Chemother. 2017;61(12):12.
  • Ceylan B, Ozansoy M, Ü K, et al. N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions. Ren Fail. 2018;40(1):423–434.
  • Arslan BY, Arslan F, Erkalp K, et al. Luteolin ameliorates colistin-induced nephrotoxicity in the rat models. Ren Fail. 2016;38(10):1735–1740.
  • Dai C, Tang S, Wang Y, et al., Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response. J Antimicrob Chemother. 72(9): 2562–2569. 2017.
  • Al-Kuraishy HM, Al-Gareeb A, Rasheed HA. Antioxidant and anti-inflammatory effects of curcumin contribute into attenuation of acute gentamicin-induced nephrotoxicity in rats. Asian J Pharm Clin Res. 2019;12(3):466–468.
  • Al-Kuraishy HM, Al-Gareeb AI, Al-Nami MS. Vinpocetine improves oxidative stress and pro-inflammatory mediators in acute kidney injury. Int J Prev Med. 2019;10:10.
  • Al-Kuraishy HM, Al-Gareeb AI, Hussien NR. Synergistic effect of berberine and pentoxifylline in attenuation of acute kidney injury. Int J Crit Illn Inj Sci. 2019;9(2):69.
  • Rasheed HA, Al-Naimi MS, Hussien NR, et al. New insight into the effect of lycopene on the oxidative stress in acute kidney injury. Int J Crit Illn Inj Sci. 2020;10(Suppl 1):11.
  • Hardeland R. Melatonin and inflammation—Story of a double‐edged blade. J Pineal Res. 2018;65(4):e12525.
  • Yousef JM, Chen G, Hill PA, et al. Melatonin attenuates colistin-induced nephrotoxicity in rats. Antimicrob Agents Chemother. 2011;55(9):4044–4049.
  • Holmes K. Toxicity of colistin and polymixin B. N Engl J Med. 1964;271:633–634.
  • Horton J, Pankey GA, Polymyxin B. colistin, and sodium colistimethate. Med Clin North Am. 1982;66(1):135–142.
  • Koch-Weser J, Vw SIDEL, Eb FEDERMAN, et al. Adverse effects of sodium colistimethate: manifestations and specific reaction rates during 317 courses of therapy. Ann Intern Med. 1970;72(6):857–868.
  • Nord NM, Hoeprich PD. Polymyxin B and colistin: a critical comparison. N Engl J Med. 1964;270(20):1030–1035.
  • Raza Z, Naureen Z. Melatonin ameliorates the drug induced nephrotoxicity: molecular insights. nefrologia. 2020;40(1):12–25.
  • Liu Y, Jia Y, Yang K, et al. Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens. Theranostics. 2020;10(23):10697.
  • Dai C, Tang S, Velkov T, et al. Colistin-induced apoptosis of neuroblastoma-2a cells involves the generation of reactive oxygen species, mitochondrial dysfunction, and autophagy. Mol Neurobiol. 2016;53(7):4685–4700. .
  • Ozyilmaz E, Ebinc FA, Derici U, et al. Could nephrotoxicity due to colistin be ameliorated with the use of N-acetylcysteine? Intensive Care Med. 2011;37(1):141–146.
  • Bozkurt I, Sharma A, Esen S. Colistin-induced nephrotoxicity and the role of N-acetylcysteine: a retrospective cohort study. J Infect Developing Countries. 2017;11(11):895–899.
  • Timuroğlu A, Muslu S, Menteş S, et al. Effect of N-Acetyl Cysteine on acute kidney injury in patients with colistin used in intensive care; retrospective study. Acta Oncologica Turcica. 2018;51(3):390–398.
  • Ajith T, Usha S, Nivitha V. Ascorbic acid and α-tocopherol protect anticancer drug cisplatin induced nephrotoxicity in mice: a comparative study. Clin Chim Acta. 2007;375(1–2):82–86.
  • Monsen ER. Dietary reference intakes for the antioxidant nutrients: vitamin C, vitamin E, selenium, and carotenoids. J Am Diet Assoc. 2000;100(6):637–640.
  • Yousef JM, Chen G, Hill PA, et al. Ascorbic acid protects against the nephrotoxicity and apoptosis caused by colistin and affects its pharmacokinetics. J Antimicrob Chemother. 2012;67(2):452–459.
  • Moon JM, Chun BJ. The efficacy of high doses of vitamin C in patients with paraquat poisoning. Hum Exp Toxicol. 2011;30(8):844–850.
  • Auer BL, Auer D, Rodgers AL. The effect of ascorbic acid ingestion on the biochemical and physicochemical risk factors associated with calcium oxalate kidney stone formation. Clin Chem Lab Med. 1998;36(3):143–148.
  • Al-Naimi MS, Rasheed HA, Hussien NR, et al. Nephrotoxicity: role and significance of renal biomarkers in the early detection of acute renal injury. J Adv Pharm Technol Res. 2019;10(3):95.
  • Dalfino L, Puntillo F, Ondok MJM, et al. Colistin-associated acute kidney injury in severely ill patients: a step toward a better renal care? A prospective cohort study. Clinl Infect Dis. 2015;61(12):1771–1777.
  • Moradi O, Sahraei Z, Asadi S From bench to bedside: colistin nephrotoxicity and vitamin E.
  • Ghlissi Z, Hakim A, Mnif H, et al. Effect of vitamin E on reversibility of renal function following discontinuation of colistin in rats: histological and biochemical investigations. Saudi J Kidney Dis Transpl. 2018;29(1):10.
  • Ghlissi Z, Hakim A, Mnif H, et al. Combined use of Vitamins E and C improve nephrotoxicity induced by colistin in rats. Saudi J Kidney Dis Transpl. 2018;29(3):545.
  • Ghlissi Z, Hakim A, Mnif H. et al. Evaluation of the protective effect of vitamins e and c on acute tubular damage induced by colistin in rat model. Am J Phytomed Clin Ther. 2015;3(1):43–53.
  • Long M, Yang S-H, Han J-X, et al. The protective effect of grape-seed proanthocyanidin extract on oxidative damage induced by zearalenone in Kunming mice liver. Int J Mol Sci. 2016;17(6):808.
  • Denes A, Lopez-Castejon G, Brough D. Caspase-1: is IL-1 just the tip of the iceberg? Cell Death Dis. 2012;3(7):e338.
  • Faubel S, Ljubanovic D, Reznikov L, et al. Caspase-1–deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis. Kidney Int. 2004;66(6):2202–2213.
  • Ozkan G, Ulusoy S, Orem A, et al. How does colistin-induced nephropathy develop and can it be treated? Antimicrob Agents Chemother. 2013;57(8):3463–3469.
  • Yue R, Hu H, Yiu KH, et al. Lycopene protects against hypoxia/reoxygenation-induced apoptosis by preventing mitochondrial dysfunction in primary neonatal mouse cardiomyocytes. PloS One. 2012;7(11):e50778.
  • Palozza P, Catalano A, Simone R, et al. Lycopene as a guardian of redox signalling. Acta Biochim Pol. 2012;59(1):1.
  • Dai C, Tang S, Deng S, et al. Lycopene attenuates colistin-induced nephrotoxicity in mice via activation of the Nrf2/HO-1 pathway. Antimicrob Agents Chemother. 2015;59(1):579–585.
  • Karbasforooshan H, Hosseini S, Elyasi S, et al. Topical silymarin administration for prevention of acute radiodermatitis in breast cancer patients: a randomized, double‐blind, placebo‐controlled clinical trial. Phytother Res. 2019;33(2):379–386.
  • Elyasi S, Shojaee FSR, Allahyari A, et al. Topical silymarin administration for prevention of capecitabine‐induced hand–foot syndrome: a randomized, double‐blinded, placebo‐controlled clinical trial. Phytother Res. 2017;31(9):1323–1329.
  • Elyasi S, Hosseini S, Niazi Moghadam MR, et al. Effect of oral silymarin administration on prevention of radiotherapy induced mucositis: a randomized, double‐blinded, placebo‐controlled clinical trial. Phytother Res. 2016;30(11):1879–1885.
  • Shahbazi F, Sadighi S, Dashti‐Khavidaki S, et al. Effect of silymarin administration on cisplatin nephrotoxicity: report from a pilot, randomized, double‐blinded, placebo‐controlled clinical trial. Phytother Res. 2015;29(7):1046–1053.
  • Dumludag B, Derici MK, Sutcuoglu O, et al. Role of silymarin (Silybum marianum) in the prevention of colistin-induced acute nephrotoxicity in rats. Drug Chem Toxicol 2020 1–8 https://doi.org/10.1080/01480545.2020.1733003
  • Hassan SMS, Youakim MF, Rizk AAE, et al. Does silybin protect against toxicity induced by polymyxin E in rat kidney? Neurourol Urodyn. 2017;36(5):1278–1287.
  • Hassan SS, Thomann C, Ettarh R, et al. Possible protective role of silybin against polymyxin E‐induced toxic effect in rat kidneys: a biochemical approach. Neurourol Urodyn. 2017;36(8):2003–2010.
  • Dinda B, Dinda S, DasSharma S, et al. Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders. Eur J Med Chem. 2017;131:68–80.
  • Lee TW, Bae E, Kim JH, et al. The aqueous extract of aged black garlic ameliorates colistin-induced acute kidney injury in rats. Ren Fail. 2019;41(1):24–33.
  • Akbari S, Kariznavi E, Jannati M, et al. Curcumin as a preventive or therapeutic measure for chemotherapy and radiotherapy induced adverse reaction: a comprehensive review. Food Chem Toxicol. 2020;145:111699.
  • Edrees NE, Galal AA, Monaem ARA, et al. Curcumin alleviates colistin-induced nephrotoxicity and neurotoxicity in rats via attenuation of oxidative stress, inflammation and apoptosis. Chem Biol Interact. 2018;294:56–64.
  • Vazin A, Heidari R, Khodami Z. Curcumin supplementation alleviates polymyxin E-induced nephrotoxicity. J Exp Pharmacol. 2020;12:129.
  • Schaffer S, Kim HW. Effects and mechanisms of taurine as a therapeutic agent. Biomol Ther (Seoul). 2018;26(3):225.
  • Heidari R, Behnamrad S, Khodami Z, et al. The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative stress. Biomed Pharmacother. 2019;109:103–111.
  • Mani R, Natesan V. Chrysin: sources, beneficial pharmacological activities, and molecular mechanism of action. Phytochemistry. 2018;145:187–196.
  • Hanedan B, Ozkaraca M, Kirbas A, et al. Investigation of the effects of hesperidin and chrysin on renal injury induced by colistin in rats. Biomed Pharmacother. 2018;108:1607–1616.
  • Wang J, Ishfaq M, Fan Q, et al. 7-hydroxycoumarin attenuates colistin-induced kidney injury in mice through the decreased level of histone deacetylase 1 and the activation of Nrf2 signaling pathway. Front Pharmacol. 2020;11:1146.
  • Arisha SM. Effect of Arabic gum aqueous extract on histological, ultrastructural, immunohistochemical and biochemical changes on colistin-induced nephropathy in male albino rats. Egypt Acad J Biol Sci D Histol Histochem. 2020;12(2):23–44.
  • Talih G, Esmaoğlu A, Bayram A, et al. Does dexmedetomidine prevent colistin nephrotoxicity? Rev Bras Anestesiol. 2018;68(4):383–387.
  • Tsuji BT, Pogue JM, Zavascki AP, et al. International consensus guidelines for the optimal use of the polymyxins: endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP). Pharmacother J Human Pharmacol Drug Ther. 2019;39(1):10–39.

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