Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study

References

• Peslak SA, Olson T, and Babushok DV. Diagnosis and treatment of aplastic anemia. Curr Treat Options Oncol. 2017;18(12):70.
   Google Scholar
• Young NS. Aplastic Anemia. N Engl J Med. 2018;25(17):1643–1656.
   Google Scholar
• Gaies E, Ben Sassi M, Charfi R, et al. Therapeutic Durg monitoring of cyclosporin using area under the curve in nephrotic syndrome. Tunis Med. 2019;97(2):360–364.
   Google Scholar
• Amundsen R, Åsberg A, Ohm IK, et al. Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro. Drug Metab Dispos. 40(4): 655–661. 2012;
   Google Scholar
• Wang DD, Ye QF, Chen X, et al. Population pharmacokinetics and initial dosing regimen optimization of cyclosporin in pediatric hemophagocytic lymphohistiocytosis patients. Xenobiotica. 2020;50(4):435–441.
   Google Scholar
• Li TF, Hu L, Ma XL, et al. Population pharmacokinetics of cyclosporine in Chinese children receiving hematopoietic stem cell transplantation. Acta Pharmacol Sin. 2019; 40(12): 1603–1610.
   Google Scholar
• Helge D, Hartung MD, Timothy S. Acquired aplastic anemia in children. Pediatr Clin North Am. 2013;60(6):1311–1336.
   Google Scholar
• Andreas HG, Robert T, Amit D, et al. Drug-drug interactions between triazole antifungal agents used to treat invasive aspergillosis and immunosuppressants metabolized by cytochrome P450 3A4. Transpl Infect Dis. 2017;19(5):1–11.
   Google Scholar
• Fu R, Tajima S, Suetsugu K, et al. Biomarkers for individualized dosage adjustments in immunosuppressive therapy using calcineurin inhibitors after organ transplantation. Acta Pharmacol Sin. 2019;40(2):151–159.
   Google Scholar
• Wang C, Lu KP, Chang Z, et al. Association of CYP3A4*1B genotype with cyclosporin A pharmacokinetics in renal transplant recipients: a meta-analysis. Gene. 2018;664:44–49.
   Google Scholar
• Choi JG, Eom SM, Kim J, et al. A comprehensive review of recent studies on herb-drug interaction: a focus on pharmacodynamic interaction. J Altern Complement Med. 2016;22(4):262–279.
   Google Scholar
• Schultz KR, Nevill TJ, Balshaw RF, et al. Effect of gastrointestinal inflammation and age on the pharmacokinetics of oral microemulsion cyclosporin A in the first month after bone marrow transplantation. Bone Marrow Transplant. 2000;26(5):545–551.
   Google Scholar
• Akool ES. Molecular mechanisms of the protective role of wheat germ oil against cyclosporin A-induced hepatotoxicity in rats. Pharm Biol. 2015;53(9):1311–1317.
   Google Scholar
• Chen ZP, Liu F, Zheng NX. Wuzhi capsule (Schisandra Sphenanthera extract) attenuates liver steatosis and inflammation during non-alcoholic fatty liver disease development. Biomed Pharmacother. 2019;110:285–293.
   Google Scholar
• Xie Y, Hao H, Kang A, et al. Integral pharmacokinetics of multiple lignan components in normal, CCl 4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers. J Ethnopharmacol. 2010;131(2):290–299.
   Google Scholar
• Loo WT, Cheung MN, Chow LW, et al. Fructus schisandrae (Wuweizi)-containing compound inhibits secretion of HBsAg and HBeAg in hepatocellular carcinoma cell line. Biomed Pharmacother. 2007;61(9):606–610.
   Google Scholar
• Chen X, Wang DD, Xu H. Optimization of initial dosing scheme of tacrolimus in pediatric refractory nephrotic syndrome patients based on CYP3A5 genotype and coadministration with wuzhi-capsule. Xenobiotica. 2020;50(5):606–613.
   Google Scholar
• Wang K, Qu QS, Zhang YX, et al. Effects of Wuzhi capsule on blood concentration of tacrolimus after renal transplantation. J Biol Regul Homeost Agents. 2016;30(1):155–159.
   Google Scholar
• Chen X, Wang DD, Xu H, et al. Initial dosage optimization of tacrolimus in Chinese pediatric patients undergoing kidney transplantation based on population pharmacokinetics and pharmacogenetics. Expert Rev Clin Pharmacol. 2020;13(5):553–561.
   Google Scholar
• Xue XP, Qin XL, Xu CS, et al. Effect of Wuzhi tablet (Schisandra sphenanthera extract) on the pharmacokinetics of cyclosporin A in rats. Phytother Res. 2013;27(8):1255–1259.
   Google Scholar
• Wim L, Bart M. In vivo assessment of cytochrome P450 3A4 and P-glycoprotein activity: impact on clinical practice. Curr Enzyme Inhib. 2007;3(3):217–241.
   Google Scholar
• Jin J, Bi H, Hu J, et al. Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats. Biopharm Drug Dispos. 2010;31(4):264–268.
   Google Scholar
• Jin J, Bi H, Hu J, et al. Effect of Wuzhi tablet (Schisandra sphenanthera extract) on the pharmacokinetics of paclitaxel in rats. Phytother Res. 2011;25(8):1250–1253.
   Google Scholar
• Wallemacq P, Armstrong VW, Brunet M, et al. Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther Drug Monit. 2009;31(2):139–152.
   Google Scholar
• Xin HW, Wu XC, Li Q, et al. Effects of Schisandra sphenanthera extract on the pharmacokinetics of midazolam in healthy volunteers. Br J Clin Pharmacol. 2009;67(5):541–546.
   Google Scholar
• Parasrampuria DA, Mendell J, Shi M, et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. Br J Clin Pharmacol. 2016;82(6):1591–1600.
   Google Scholar
• Fan JJ, Chen L, Lu XQ, et al. The pharmacokinetic prediction of cyclosporin A after coadministration with Wuzhi capsule. AAPS PharmSciTech. 20(6): 1–7. 2019;
   Google Scholar
• Rezzani R. Exploring cyclosporine A-side effects and the protective role-played by antioxidants: the morphological and immunohistochemical studies. Histol Histopathol. 2006;21(3):301–316.
   Google Scholar
• Zeng H, Li D, Qin X, et al. Hepatoprotective effects of Schisandra sphenanthera extract against lithocholic acid-induced cholestasis in male mice are associated with activation of the pregnane X receptor pathway and promotion of liver regeneration. Drug Metab Dispos. 2016;44(3):337–342.
   Google Scholar
• Khadir F, Pouramir M, Joorsaraee SG, et al. The effect of arbutin on lipid peroxidation and antioxidant capacity in the serum of cyclosporine-treated rats. Caspian Journal of Internal Medicine. 2015;6(4):196–200.
   Google Scholar