8
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Torquetenovirus from bronchoalveolar lavage fluid as a biomarker for lung infection among immunocompromised hosts

, , , & ORCID Icon
Received 01 Jan 2024, Accepted 08 May 2024, Published online: 09 Jul 2024

References

  • Chai J, Han X, Mei Q, et al. Clinical characteristics and mortality of non-tuberculous mycobacterial infection in immunocompromised vs immunocompetent hosts. Front Med (Lausanne). 2022;9:884446. doi:10.3389/fmed.2022.884446
  • Singson JRC, Kirley PD, Pham H, et al. Factors associated with severe outcomes among immunocompromised adults hospitalized for COVID-19 - COVID-NET, 10 states, March 2020-February 2022. Morb Mortal Wkly Rep. 2022;71:878–884. doi:10.15585/mmwr.mm7127a3
  • Azoulay E, Russell L, Van de Louw A, et al. Diagnosis of severe respiratory infections in immunocompromised patients. Intensive Care Med. 2020;46:298–314. doi:10.1007/s00134-019-05906-5
  • Eldar-Yedidia Y, Ben-Shalom E, Hillel M, et al. Association of post-transplantation anellovirus viral load with kidney transplant rejection in children. Pediatr Nephrol. 2022;37:1905–1914. doi:10.1007/s00467-021-05336-w
  • Dumas G, Bertrand M, Lemiale V, et al. Prognosis of critically ill immunocompromised patients with virus-detected acute respiratory failure. Ann Intensive Care. 2023;13:101. doi:10.1186/s13613-023-01196-9
  • Kreitmann L, Gaudet A, Nseir S. Ventilator-associated pneumonia in immunosuppressed patients. Antibiotics (Basel). 2023;12:413. doi:10.3390/antibiotics12020413
  • Azoulay E, Mokart D, Kouatchet A, et al. Acute respiratory failure in immunocompromised adults. Lancet Respir Med. 2019;7:173–186. doi:10.1016/s2213-2600(18)30345-x
  • Kapandji N, Darmon M, Valade S, et al. Clinical significance of human metapneumovirus detection in critically ill adults with lower respiratory tract infections. Ann Intensive Care. 2023;13:21. doi:10.1186/s13613-023-01117-w
  • Jin X, Li J, Shao M, et al. Improving suspected pulmonary infection diagnosis by bronchoalveolar lavage fluid metagenomic next-generation sequencing: a multicenter retrospective study. Microbiol Spectr. 2022;10:e0247321. doi:10.1128/spectrum.02473-21
  • Honorato L, Witkin SS, Mendes-Correa MC, et al. The torque teno virus titer in saliva reflects the level of circulating CD4(+) T lymphocytes and HIV in individuals undergoing antiretroviral maintenance therapy. Front Med (Lausanne). 2021;8:809312. doi:10.3389/fmed.2021.809312
  • Pradier A, Masouridi-Levrat S, Bosshard C, et al. Torque teno virus as a potential biomarker for complications and survival after allogeneic hematopoietic stem cell transplantation. Front Immunol. 2020;11:998. doi:10.3389/fimmu.2020.00998
  • Lim EY, Jackson SE, Wills MR. The CD4+ T cell response to human cytomegalovirus in healthy and immunocompromised people. Front Cell Infect Microbiol. 2020;10:202. doi:10.3389/fcimb.2020.00202
  • Schmidt L, Jensen BO, Walker A, et al. Torque teno virus plasma level as novel biomarker of retained immunocompetence in HIV-infected patients. Infection. 2021;49:501–509. doi:10.1007/s15010-020-01573-7
  • Mouton W, Conrad A, Bal A, et al. Torque teno virus viral load as a marker of immune function in allogeneic haematopoietic stem cell transplantation recipients. Viruses. 2020;12:1292. doi:10.3390/v12111292
  • Studenic P, Bond G, Kerschbaumer A, et al. Torque teno virus quantification for monitoring of immunomodulation with biological compounds in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2021;61:2815–2825. doi:10.1093/rheumatology/keab839
  • van Rijn AL, Wunderink HF, Sidorov IA, et al. Torque teno virus loads after kidney transplantation predict allograft rejection but not viral infection. J Clin Virol. 2021;140:104871. doi:10.1016/j.jcv.2021.104871
  • Gore EJ, Gomes-Neto AW, Wang L, et al. Torquetenovirus serum load and long-term outcomes in renal transplant recipients. J Clin Med. 2020;9:440. doi:10.3390/jcm9020440
  • Solis M, Gallais F, Garnier-Kepka S, et al. Combining predictive markers for severe COVID-19: torquetenovirus DNA load and SARS-CoV-2 RNAemia. J Clin Virol. 2022;148:105120. doi:10.1016/j.jcv.2022.105120
  • Mallet F, Diouf L, Meunier B, et al. Herpes DNAemia and TTV viraemia in intensive care unit critically ill patients: a single-centre prospective longitudinal study. Front Immunol. 2021;12:698808. doi:10.3389/fimmu.2021.698808
  • Pescarmona R, Mouton W, Walzer T, et al. Evaluation of TTV replication as a biomarker of immune checkpoint inhibitors efficacy in melanoma patients. PLOS ONE. 2021;16:e0255972. doi:10.1371/journal.pone.0255972
  • Grenda R. Torque teno (TTV) viral load as a biomarker of immunosuppressive strength after kidney transplantation in children. Pediatr Nephrol. 2021;36:1–3. doi:10.1007/s00467-020-04607-2
  • Peng JM, Du B, Qin HY, et al. Metagenomic next-generation sequencing for the diagnosis of suspected pneumonia in immunocompromised patients. J Infect. 2021;82:22–27. doi:10.1016/j.jinf.2021.01.029
  • Antonelli M, Moreno R, Vincent JL, et al. Application of SOFA score to trauma patients. Sequential organ failure assessment. Intensive Care Med. 1999;25:389–394. doi:10.1007/s001340050863
  • Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:801–810. doi:10.1001/jama.2016.0287
  • Patterson TF, Thompson GR 3rd, Denning DW, et al. Practice guidelines for the diagnosis and management of Aspergillosis: 2016 update by the Infectious Diseases Society of America. Clin Infect Dis. 2016;63:e1–e60. doi:10.1093/cid/ciw326
  • Gopalaswamy R, Shanmugam S, Mondal R, et al. Of tuberculosis and non-tuberculous mycobacterial infections - a comparative analysis of epidemiology, diagnosis and treatment. J Biomed Sci. 2020;27:74. doi:10.1186/s12929-020-00667-6
  • Ku JH, Henkle E, Aksamit TR, et al. Treatment of nontuberculous mycobacterial (NTM) pulmonary infection in the US bronchiectasis and NTM registry: treatment patterns, adverse events, and adherence to American Thoracic Society/Infectious Disease Society of America Treatment Guidelines. Clin Infect Dis. 2023;76:338–341. doi:10.1093/cid/ciac788
  • Yuan X, Xie L, Shi Z, et al. Application of mNGS in the study of pulmonary microbiome in pneumoconiosis complicated with pulmonary infection patients and exploration of potential biomarkers. Front Cell Infect Microbiol. 2023;13:1200157. doi:10.3389/fcimb.2023.1200157
  • Zhang X, Tang X, Yi X, et al. Etiologic characteristics revealed by mNGS-mediated ultra-early and early microbiological identification in airway secretions from lung transplant recipients. Front Immunol. 2023;14:1271919. doi:10.3389/fimmu.2023.1271919
  • Fang EE, Nyasa RB, Ndi EM, et al. Investigating the risk factors for seroprevalence and the correlation between CD4+ T-cell count and humoral antibody responses to Toxoplasma gondii infection amongst HIV patients in the Bamenda Health District, Cameroon. PLOS ONE. 2021;16:e0256947. doi:10.1371/journal.pone.0256947
  • Heck C, Steiner S, Kaebisch EM, et al. CD4+ T cell dependent b cell recovery and function after autologous hematopoietic stem cell transplantation. Front Immunol. 2021;12:736137. doi:10.3389/fimmu.2021.736137
  • Imoto S, Suzukawa M, Takeda K, et al. Evaluation of tuberculosis diagnostic biomarkers in immunocompromised hosts based on cytokine levels in QuantiFERON-TB Gold Plus. Tuberculosis (Edinb). 2022;136:102242. doi:10.1016/j.tube.2022.102242
  • Doorenbos CSE, Jonker J, Hao J, et al. Smoking, alcohol intake and torque teno virus in stable kidney transplant recipients. Viruses. 2023;15:2387. doi:10.3390/v15122387
  • Jaksch P, Görzer I, Puchhammer-Stöckl E, et al. Integrated immunologic monitoring in solid organ transplantation: the road toward torque teno virus-guided Immunosuppression. Transplantation. 2022;106:1940–1951. doi:10.1097/tp.0000000000004153
  • Studenic P, Bond G, Kerschbaumer A, et al. Torque teno virus quantification for monitoring of immunomodulation with biologic compounds in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2022;61:2815–2825. doi:10.1093/rheumatology/keab839
  • Querido S, Martins C, Gomes P, et al. Kinetics of torque teno virus viral load is associated with infection and de novo donor specific antibodies in the first year after kidney transplantation: a prospective cohort study. Viruses. 2023;15:1464. doi:10.3390/v15071464
  • Budden KF, Shukla SD, Rehman SF, et al. Functional effects of the microbiota in chronic respiratory disease. Lancet Respir Med. 2019;7:907–920. doi:10.1016/s2213-2600(18)30510-1
  • Sun L, Zhang S, Yang Z, et al. Clinical application and influencing factor analysis of metagenomic next-generation sequencing (mNGS) in ICU patients with sepsis. Front Cell Infect Microbiol. 2022;12:905132. doi:10.3389/fcimb.2022.905132
  • Freer G, Maggi F, Pifferi M, et al. The virome and its major component, anellovirus, a convoluted system molding human immune defenses and possibly affecting the development of asthma and respiratory diseases in childhood. Front Microbiol. 2018;9:686. doi:10.3389/fmicb.2018.00686
  • Mac Aogáin M, Chandrasekaran R, Lim AYH, et al. Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study. EurRespirJ. 2018;52:1800766. doi:10.1183/13993003.00766-2018
  • Yagi K, Huffnagle GB, Lukacs NW, et al. The lung microbiome during health and disease. Int J Mol Sci. 2021;22:10872. doi:10.3390/ijms221910872
  • Lv M, Zhu C, Zhu C, et al. Clinical values of metagenomic next-generation sequencing in patients with severe pneumonia: a systematic review and meta-analysis. Front Cell Infect Microbiol. 2023;13:1106859. doi:10.3389/fcimb.2023.1106859
  • Xu P, Yang K, Yang L, et al. Next-generation metagenome sequencing shows superior diagnostic performance in acid-fast staining sputum smear-negative pulmonary tuberculosis and non-tuberculous mycobacterial pulmonary disease. Front Microbiol. 2022;13:898195. doi:10.3389/fmicb.2022.898195
  • Lin T, Tu X, Zhao J, et al. Microbiological diagnostic performance of metagenomic next-generation sequencing compared with conventional culture for patients with community-acquired pneumonia. Front Cell Infect Microbiol. 2023;13:1136588. doi:10.3389/fcimb.2023.1136588
  • Pan L, Wu F, Cai Q, et al. Whole genome profiling of lung microbiome in solid organ transplant recipients reveals virus involved microecology may worsen prognosis. Front Cell Infect Microbiol. 2022;12:863399. doi:10.3389/fcimb.2022.863399
  • Moldoveanu B, Gearhart AM, Jalil BA, et al. Pulmonary aspergillosis: spectrum of disease. Am J Med Sci. 2021;361:411–419. doi:10.1016/j.amjms.2020.12.009
  • Tiew PY, Thng KX, Chotirmall SH. Clinical Aspergillus signatures in COPD and bronchiectasis. J Fungi (Basel). 2022;8:480. doi:10.3390/jof8050480
  • Forqué L, Albert E, Giménez E, et al. Monitoring of torque teno virus DNAemia in critically ill COVID-19 patients: may it help to predict clinical outcomes? J Clin Virol. 2022;148:105082. doi:10.1016/j.jcv.2022.105082
  • Mendes-Correa MC, Tozetto-Mendoza TR, Freire WS, et al. Torquetenovirus in saliva: a potential biomarker for SARS-CoV-2 infection? PLOS ONE. 2021;16:e0256357. doi:10.1371/journal.pone.0256357
  • Doberer K, Schiemann M, Strassl R, et al. Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients-A prospective observational trial. Am J Transplant. 2020;20:2081–2090. doi:10.1111/ajt.15810
  • Peker BO, Daloğlu AE, Görzer I, et al. Investigation of torque teno virus (TTV) DNA as an immunological and virological marker in pediatric hematopoietic stem cell transplantation (HSCT) patients. Microb Pathog. 2020;149:104397. doi:10.1016/j.micpath.2020.104397

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.