44
Views
0
CrossRef citations to date
0
Altmetric
Systematic Review

The concentration of platelets in PRP does not affect pain outcomes in lateral epicondylitis: a systematic review and meta-analysis

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, , , & show all
Pages 223-233 | Received 04 Oct 2023, Accepted 23 May 2024, Published online: 14 Jun 2024

References

  • Ulusoy I, Kivrak A. Is blood group a risk factor in lateral epicondylitis? Eur Rev Med Pharmacol Sci. 2023;27(9):3947–3956. doi:10.26355/eurrev_202305_32301
  • Kıvrak A, Ulusoy I. Comparison of the clinical results of platelet-rich plasma, steroid and autologous blood injections in the treatment of chronic lateral epicondylitis. Healthcare (Basel). 2023;11(5):767. doi:10.3390/healthcare11050767
  • Vaquero-Picado A, Barco R, Antuña SA. Lateral epicondylitis of the elbow. EFORT Open Rev. 2017;1(11):391–397. doi:10.1302/2058-5241.1.000049
  • Konarski W, Poboży T. A clinical overview of the natural course and management of lateral epicondylitis. Orthopedics. 2023;46(4):e210–e218. doi:10.3928/01477447-20230329-05
  • Lenoir H, Mares O, Carlier Y. Management of lateral epicondylitis. Orthop Traumatol Surg Res. 2019;105(8S):S241–S246. doi:10.1016/j.otsr.2019.09.004
  • Ahmed AF, Rayyan R, Zikria B, et al. Lateral epicondylitis of the elbow: an up-to-date review of management. Eur J Orthop Surg Traumatol. 2023;33(2):201–206. doi:10.1007/s00590-021-03181-z
  • Sims S, Miller K, Elfar J, et al. Non-surgical treatment of lateral epicondylitis: a systematic review of randomized controlled trials. Hand. 2014;9:419–446.
  • Dejnek M, Moreira H, Płaczkowska S, et al. Effectiveness of lateral elbow tendinopathy treatment depends on the content of biologically active compounds in autologous platelet-rich plasma. J Clin Med. 2022;11(13):3687. doi:10.3390/jcm11133687
  • Dhurat R, Sukesh M. Principles and methods of preparation of platelet-rich plasma: a review and author's perspective. J Cutan Aesthet Surg. 2014;7(4):189–197. doi:10.4103/0974-2077.150734
  • Amable P, Carias R, Teixeira M, et al. Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors. Stem Cell Res Ther. 2013;4(3):67. doi:10.1186/scrt218
  • Can U, Kivrak M, Kayaalp E, et al. Peritendinous injection of platelet-rich plasma to treat tendinopathy: a retrospective review. AOTT. 2017;51:482–487. doi:10.1016/j.aott.2017.10.003
  • Yerlikaya M, Çalis T, Sütbeyaz T, et al. Comparison of effects of leukocyte-rich and leukocyte-poor platelet-rich plasma on pain and functionality in patients with lateral epicondylitis. Arch Rheumatol. 2017;33(1):73–79. doi:10.5606/ArchRheumatol.2018.6336
  • Hohmann E, Tetsworth K, Glatt V. Corticosteroid injections for the treatment of lateral epicondylitis are superior to platelet-rich plasma at 1 month but platelet-rich plasma is more effective at 6 months: an updated systematic review and meta-analysis of level 1 and 2 studies. J Shoulder Elbow Surg. 2023;32(9):1770–1783. doi:10.1016/j.jse.2023.04.018
  • Lim W, Park S, Kim B, et al. Relationship of cytokine levels and clinical effect on platelet-rich plasma-treated lateral epicondylitis. J Orthop Res. 2018;36:913–920. doi:10.1002/jor.23714
  • Shamseer L, Moher D, Clarke M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;350:g7647. doi:10.1136/bmj.g7647. Erratum in: BMJ. 2016;354:i4086.
  • Li S, Yang G, Zhang H, et al. A systematic review on the efficacy of different types of platelet-rich plasma in the management of lateral epicondylitis. J Shoulder Elbow Surg. 2022;31(7):1533–1544. doi:10.1016/j.jse.2022.02.017
  • Guyatt G, Oxman A, Akl E, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J. Clin. Epidemiol. 2011;64(4):383–394. doi:10.1016/j.jclinepi.2010.04.026
  • Sterne J, Hernán M, Reeves B, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919. doi:10.1136/bmj.i4919
  • Wells G, Shea B, O'Connell D, et al. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Non-Randomized Studies in Meta-Analysis. 2000.
  • Sterne J, Savovi´ J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898. doi:10.1136/bmj.l4898
  • Haddaway NR, Page MJ, Pritchard CC, et al. PRISMA2020: An R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis. Campbell Systematic Reviews. 2022;18:e1230. doi:10.1002/cl2.1230
  • Evans JP, Porter I, Gangannagaripalli JB, et al. Assessing patient-centred outcomes in lateral elbow tendinopathy: a systematic review and standardised comparison of english language clinical rating systems. Sports Med Open. 2019;5(1):10. doi:10.1186/s40798-019-0183-2
  • Peerbooms JC, Sluimer J, Bruijn DJ, et al. Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am J Sports Med. 2010;38(2):255–262. doi:10.1177/0363546509355445
  • Thanasas C, Papadimitriou G, Charalambidis C, et al. Platelet-rich plasma versus autologous whole blood for the treatment of chronic lateral elbow epicondylitis: a randomized controlled clinical trial. Am J Sports Med. 2011;39(10):2130–2134. doi:10.1177/0363546511417113
  • Omar A, Ibrahim M, Ahmed A, et al. Local injection of autologous platelet rich plasma and corticosteroid in treatment of lateral epicondylitis and plantar fasciitis: randomized clinical trial. Egyptian Rheumatologist. 2012;34:43–49. doi:10.1016/j.ejr.2011.12.001
  • Krogh T, Fredberg U, Stengaard-Pedersen K, et al. Treatment of lateral epicondylitis with platelet-rich plasma, glucocorticoid or saline: a randomized, double-blind, placebo-controlled trial. Am J Sports Med. 2013;41(3):625–635. doi:10.1177/0363546512472975
  • Raeissadat SA, Rayegani SM, Hassanabadi H, Rahimi R, Sedighipour L, Rostami K. Is Platelet-rich plasma superior to whole blood in the management of chronic tennis elbow: one year randomized clinical trial. BMC Sports Sci Med Rehabil. 2014;6:12. doi:10.1186/2052-1847-6-12
  • Raeissadat SA, Sedighipour L, Rayegani SM, Bahrami MH, Bayat M, Rahimi R. Effect of Platelet-Rich Plasma (PRP) versus Autologous Whole Blood on Pain and Function Improvement in Tennis Elbow: A Randomized Clinical Trial. Pain Res Treat. 2014;2014:191525. doi:10.1155/2014/191525
  • Zhao LL, Tong PJ, Xiao LW, Zhu QL, Xu B, Yan MH. [Case-control study on local injection of autoallergic platelet rich plasma or whole blood for the treatment of tennis elbow]. Zhongguo Gu Shang. 2014;27(11):908–911. Chinese.
  • Behera P, Dhillon M, Aggarwal S, Marwaha N, Prakash M. Leukocyte-poor platelet-rich plasma versus bupivacaine for recalcitrant lateral epicondylar tendinopathy. J Orthop Surg (Hong Kong). 2015;23(1):6–10. doi:10.1177/230949901502300102
  • Brkljac M, Kumar S, Kalloo D, Hirehal K. The effect of platelet-rich plasma injection on lateral epicondylitis following failed conservative management. J Orthop. 2015;12(Suppl. 2):S166–S170. doi:10.1016/j.jor.2015.10.018
  • Glanzmann MC, Audigé L. Platelet-rich plasma for chronic lateral epicondylitis: is one injection sufficient? Arch Orthop Trauma Surg. 2015;135(12):1637–1645. doi:10.1007/s00402-015-2322-7
  • Montalvan B, Le Goux P, Klouche S, Borgel D, Hardy P, Breban M. Inefficacy of ultrasound-guided local injections of autologous conditioned plasma for recent epicondylitis: results of a double-blind placebo-controlled randomized clinical trial with one-year follow-up. Rheumatology (Oxford). 2016;55(2):279–285. doi:10.1093/rheumatology/kev326
  • Merolla G, Dellabiancia F, Ricci A, et al. Arthroscopic Debridement Versus Platelet-Rich Plasma Injection: A Prospective, Randomized, Comparative Study of Chronic Lateral Epicondylitis With a Nearly 2-Year Follow-Up. Arthroscopy. 2017;33(7):1320–1329. doi:10.1016/j.arthro.2017.02.009
  • Khattab EM, Abowarda MH. Role of Ultrasound Guided Platelet-Rich Plasma (PRP) Injection in Treatment of Lateral Epicondylitis. Egyptian J Radiology Nuclear Medicine. 2017;48. doi:10.1016/j.ejrnm.2017.03.002
  • Alessio-Mazzola M, Repetto I, Biti B, Trentini R, Formica M, Felli L. Autologous US-guided PRP injection versus US-guided focal extracorporeal shock wave therapy for chronic lateral epicondylitis: a minimum of 2-year follow-up retrospective comparative study. J Orthop Surg (Hong Kong). 2018;26(1):2309499017749986. doi:10.1177/2309499017749986
  • Boden AL, Scott MT, Dalwadi PP, Mautner K, Mason RA, Gottschalk MB. Platelet-rich plasma versus Tenex in the treatment of medial and lateral epicondylitis. J Shoulder Elbow Surg. 2019;28(1):112–119. doi:10.1016/j.jse.2018.08.032
  • Linnanmäki L, Kanto K, Karjalainen T, Leppänen OV, Lehtinen J. Platelet-rich plasma or autologous blood do not reduce pain or improve function in patients with lateral epicondylitis: a randomized controlled trial. Clin Orthop Relat Res. 2020;478(8):1892–1900. doi:10.1097/CORR.0000000000001185
  • Park H-S, Jo SM, Dasari S, Moon YL. Comparison of clinical outcomes of platelet-rich plasma for epicondylitis, elbow: simultaneous lateral and medial versus lateral versus medial. Orthop Surg. 2023;15. doi:10.1111/os.13732
  • Kamble P, Prabhu RM, Jogani A, Mohanty SS, Panchal S, Dakhode S. Is ultrasound (US)-guided platelet-rich plasma injection more efficacious as a treatment modality for lateral elbow tendinopathy than US-guided steroid injection?: A prospective triple-blinded study with midterm follow-up. Clin Orthop Surg. 2023;15(3):454–462. doi:10.4055/cios22128
  • Sağlam G, Çetinkaya D. Ultrasound-guided versus palpation-guided platelet-rich plasma injection for the treatment of chronic lateral epicondylitis: a prospective, randomized study. Arch Rheumatol. 2022;38(1):67–74. doi:10.46497/ArchRheumatol.2023.9196
  • McGuinness L, Higgins J. Risk-of-bias VISualization (robvis): An R package and Shiny web app for visualizing risk-of-bias assessments. Res Syn Meth. 2020;1–7. doi:10.1002/jrsm.1411
  • Karcioglu O, Topacoglu H, Dikme O, et al. A systematic review of the pain scales in adults: which to use? Am J Emerg Med. 2018;36(4):707–714. doi:10.1016/j.ajem.2018.01.008
  • Williamson A, Hoggart B. Pain: a review of three commonly used pain rating scales. J Clinical Nursing. 2005;14(7):798–804. doi:10.1111/j.1365-2702.2005.01121.x

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.