Pathogenic Tracks in Fatigue Syndromes

References

• Holmes GP. Kaplan JE, Gantz NM, el al. Chronic fatigue syndrome: a working case definition. Ann Intern MedAMX. 108: 387–9.
   Google Scholar
• Barnes DM. Mystery disease ai Lake Tahoe challenges virologists and clinicians. Science.19X6, 234:541–2.
   Google Scholar
• Holmes GP. Kaplan JE, Stewart J A. Hunt B, PinskyPF, Schocnbcrgcr LB. A cluster of patients with a chronic mononucleosis-like syndrome: is Epstein-Barr virus the causcl JAMA. 1987; 257:2297–302.
   Google Scholar
• Sharpe MC, Archard LC, Banatvala JE et al. A report-chronic fatigue syndrome: guidelines for research. J R Soc Med. 1991; 84: 118–21
   Google Scholar
• Lloyd AR. Wakefield D, Boughton C, Dwyer J. What is myalgic encephalomyelitis? Lancet. 1988; 1: 1286–87
   Google Scholar
• Bates DW. Buchwald D, Lee J et al. A comparison of case definitions of chronic fatigue syndrome. Clin InfectDis. 1994; 18(Suppl I): SI 1–5.
   Google Scholar
• Beard G. Neurasthenia, or nervous exhaustion. Boston Med Surg. 1869; 3:217–20.
   Google Scholar
• Evans AC. Brucellosis in the United Stales. Am J Public Health. 1947; 37: 139–51.
   Google Scholar
• Yager J, Young RT. Non-hypoglyccmia is an epidemic condition. N EnglJ Med. 1974; 291: 907–8.
   Google Scholar
• Jones JF, Ray CG, Minnich LL, Hicks MT, Kibler R, Lucas DO. Evidence for active Epstein-Barr virus infection in patients with persistent, unexplained illnesses: elevated anti-early antigen antibodies. Ann Intern Med. 1985; 102: 1–7
   Google Scholar
• Smith DG. Myalgic encephalomyelitis. In: The Royal College of General Practionners Members; Reference Book. London: Sabecrow Publishing. 1988: 247–50.
   Google Scholar
• Wolfe F. Smythe HA, Yunus MB et al. The American college of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee. Arthritis Rheum. 1990, 33: 160–72.
   Google Scholar
• Straus SE, Tosato G, Armstong G et al. Persisting illness and fatigue in adults with evidence of Epstein-Barr virus infection. Ann Intern Med. 1985; 102: 7–16.
   Google Scholar
• Sumaya CV. Serologic and virologic epidemiology of Epstein-Barr virus: relevance to chronic fatigue syndrome. Rev Inf Dif.1991; 13(Suppl I): S19-S25
   Google Scholar
• Levine H. Jacobson S, Pocinki AG et al. Clinical, epidemiological, and virological studies in four clusters of the chronic fatigue syndrome. Arch liitern Med. 1992; 152: 1611–16.
   Google Scholar
• Miller G, Grogan E, Rowe D et al. Selective lack of antibody to a component of EBV nuclear antigen in patients with chronic active Epstein-Barr virus infection. J Infect Dis. 1987; 156: 26–35.
   Google Scholar
• Buchwald D, Cheney PR, Peterson DL et al. A chronic illness characterized by fatigue, neurologic and immunological disorders, and active human herpesvirus type 6 infection. Ann Intern Med. 1992; 116: 103–13
   Google Scholar
• Gupta S, Vayuvegula B. A comprehensive immunological analysis in chronic fatigue syndrome. Scand J Immunol. 1991; 33: 319–27.
   Google Scholar
• Yamanishi K. OkunoT, Shiraki K et al. Identifica tion of human herpcsvirusas a causal agent for cxanthem subitum. Lancet. 1988; 1: 1065–67.
   Google Scholar
• Gold D, Bowden R, Sixbey J et al. Chronic fatigue: a prospective clinical and virologic study. JAMA 1990; 264: 48–53.
   Google Scholar
• Wray BB.GaughfC, Chandler FW et al. Detection of Epstein-Barr virus and cytomegalovirus in patients with chronic fatigue. Ann Allergy. 1993; 71: 223–6.
   Google Scholar
• Jones J F. Serologic and immunologic responses in chronic fatigue syndrome with emphasis of the Epstein-Barr virus. Rev Infect Dis. 1991; 13(suppl I): S26-S3I.
   Google Scholar
• Tosato G, Straus S, Henle W. Pike SE, Blaesc RM. Characteristic T cell dysfunction in patients with chronic active Epstein-Barr virus infection (chronic infectious mononucleosis). J Immunol. 1985; 134: 3082–84.
   Google Scholar
• Josephs SF, Hcmy B, Balachandran N et al. HHV-6 reactivation in chronic fatigue syndrome. Lancet. 1991;1:817–8.
   Google Scholar
• Lusso P, Malnati MS, Garzino-Demo A, et al. Infection of natural killer cells by human herpesvirus-6. Nature. 1993;362:458–62.
   Google Scholar
• Glaser R, Pearson GR, Jones JF et al. Stress-related activation of Epstein-Barr virus. Brain Beluiv Immun. 1991; 5:219–32.
   Google Scholar
• Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to-different functional properties. Annu Rev Immunol. 1989; 7: 145–73.
   Google Scholar
• Romagni S. Lymphokine production by human T-cells in disease states. Annu Rev Immunol. 1994; 12:227–57
   Google Scholar
• Miller NA, Carmichael HA. Calder BD et al. Antibody to Coxsackie B virus in diagnosing postviral fatigue syndrome. Br Med J. 1991; 302: 140–3.
   Google Scholar
• Gow J, Behan WMH, Clcmcnls GB, Woodall C, Riding M, Bchan PO. Entcroviral scqucnccs detected by polymerase chain reaction in muscle biopsies of patients with the postviral fatigue syndrome. Lancet. 1988, 1: 146–7.
   Google Scholar
• Behan PO. Bchan WMH, Bell EJ. The postvital fatigue syndrome-an analysis of the findings in 50 cases. J Infect. 1985; 10:211–2.
   Google Scholar
• Yousscf GE, Mann GF, Smith DG, Bell EJ, McCartney RA. Chronic enterovirus infection in patients with postviral fatigue syndrome. Lancet. 1988; 1: 146–7.
   Google Scholar
• Archard LC, Bowles NE, Behan PO, Bell EJ, Doyle D. Post viral fatigue syndrome is associated with the abnormal production of entcroviral RNA in muscle and elevated creatine kinase. J Roy Sac Med. 1988;81: 326–9.
   Google Scholar
• Gow J. Behan WMH, Clements GB, Woodall C, Riding M, Bchan PO. Entcroviral sequences detected by polymerase chain reaction in muscle biopsies of patients with the postviral fatigue syndrome. Br J Med. 1991; 302: 692–6.
   Google Scholar
• Gow JW. Bchan WMH. Simpson K, McGarry F, Keir S, Bcahn PO. Studies on enterovirus in patients with chronic fatigue syndrome. Clin Infect Dis. 1994; 18(Suppl 1): S126–9
   Google Scholar
• DeFreitas E. Hilliard B, Cheney PR ct al. Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome. Proc Null Acad Sci USA. 1991; 88: 2922–26.
   Google Scholar
• Khan AS, Hencine WM, Chapman LE ct al. Assessment of a retrovirus sequence and possible risk factors for the chronic fatigue syndrome in adults. Ann Intern Med. 1993; 118: 241–5.
   Google Scholar
• Gow JW. Simpson K, Schliephake A et al. Search for retrovirus in the chronic fatigue syndrome. J Clin Pathol. 1992; 45: 1058–61.
   Google Scholar
• Martin WJ. Chronic fatigue syndrome. Science. 1992; 255: 1726–28.
   Google Scholar
• Flugel RM, Mahnke C, Geiger A, KomarolT AL. Absence of antibody to human spumaretrovinis in patients with chronic fatigue syndrome. Clin Infect Dis. 1992; 14: 623–4.
   Google Scholar
• Hcneine W, Woods T, Sinha S et al. Lack of evidence for infection with known human and animal retroviruses in patients with chronic fatigue syndrome. Clin Infect Dis. 1994; 18(Suppl I): S121–5.
   Google Scholar
• Straus SE. Fritz S. Dale JK. Gould B, Strober W. Lymphocytc phenotype and function in the chronic fatigue syndrome. J Clin Immunol. 1993; 13: 30–40.
   Google Scholar
• Barker E, Fujimura S, Fadem MB, Landay AL, Levy JA. Immunolgical abnormalities associated with chronic fatigue syndrome. Clin Infect Dis. 1994; 18(Suppl I): S136–4I
   Google Scholar
• Lloyd A. Hickie I. Hickic C, Wakefield D. Cellmediated immunity in patients with chronic fatigue syndrome, healthy control subjects and patients with major depression. Clin Exp Immunol 1992; 87: 76–9
   Google Scholar
• Buchwald D, Komaroff AL. Review of laboratory findings for patients with chronic fatigue syndrome. Rev Infect Dis. 1991; 13(suppl I): S12–8.
   Google Scholar
• Barker E, Fujimura SF, Fadem MB, Landay AL. Levy JA. Immunological abnormalities associated with chronic fatigue syndrome. Clin Infect Dis. 1994; I8(suppl I): SI36–41.
   Google Scholar
• Laurence J. T-cell subsets in health, infectious disease, and idiopathic CD4+ T lymphocytopenia. Ann Intern Med. 1993; 119: 55–62.
   Google Scholar
• Landay AL, Jessop C. Lennettc ET, Levy JA. Chronic fatigue syndrome: clinical condition associated with immune activation. Lancet. 1991; 338: 707–12.
   Google Scholar
• Lloyd AR, Wakefield D. Boughton CR, Dwyer JM. Immunological abnormalities in the chronic fatigue syndrome. Med J Aust. 1989; 151: 122–4
   Google Scholar
• Klimas NG, Salvato FR, Morgan R, Fletcher MA. Immunological abnormalities in chronic fatigue syndrome. J Clin Microl). 1990; 28: 1403–10
   Google Scholar
• Murdoch JC. Cell-mediated immunity in patients with myalgic encephalomyelitis. NZMedJ. 1988; 101:511–2.
   Google Scholar
• Lloyd AR, Hickie I, Boughton CR, Spencer O, Wakefield D. The prevalence of chronic fatigue syndrome in Australian population. Med J Aust. 1990; 153: 522–8.
   Google Scholar
• Subira ML. Castilla A. Civeira MP. Prieto J. Deficient display of CD3 on lymphocytes of patients with chronic fatigue syndrome. J Infect Dis. 1989; 160: 165–6.
   Google Scholar
• Cheney PR. Dorman SE. Intcrlcukin-2 and the chronic fatigue syndrome. Ann Intern Med. 1989; 110: 321.
   Google Scholar
• Straus SE. Dale JK, Wright R, Peter JB. Dinarello CA. Circulating lymphokine levels in the chronic fatigue syndrome. J Infect Dis. 1989; 160: 108586.
   Google Scholar
• Lloyd A, Hickic I, Brockman A, Dwyer J. Wakefiled D. Scrum and cerebrospinal fluid cytokine levels in patients with chronic fatigue syndrome and control subjects. J Infect Dis. 1991; 164: 1023–24.
   Google Scholar
• Chao CC, Janoff En. Hu S ct al. Altered cytokine release in peripheral blood monouclcarcell cultures from patients with the chronic fatigue syndrome. Cytokine. 1991; 3: 292–8.
   Google Scholar
• Linde A, Andcrsson B, Svenson SB, et al. Seruin levels of lymphokines and soluble ccllular receptors in primary Epstcin-Barr vims infection and in patients with chronic fatigue syndrome. J Infect Dis. 1992; 165: 994–5.
   Google Scholar
• Patarca R, Klimas NG, Lugtcndorf S, Antoni M, Fletcher MA. Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with ccllular sources and patterns of soluble immune mediator expression. Clin Infect Dis. 1994; 18(Suppl I): SI47–53.
   Google Scholar
• Kiblcr R, Lucas DO, Hicks MJ, Poulos BT. Jones JF. Immune function in chronic active Epstcin-Barr virus infection. J Clin. 1985; 5: 46–54.
   Google Scholar
• Caligiuri M. Murray C, Buchwald D, et al. Phenotypic and functional deficiency of natural killer cells in patients with the chronic fatigue syndrome. J Immunol. 1987; 139: 3306–13.
   Google Scholar
• Gin W, Christiansen FT, Peter JB. Immune function and chronic fatigue syndrome. Med J Aust. 1989; 151: 117–8.
   Google Scholar
• Ojo-Amaizc EA, Conlcy EJ, Peter JB. Decreased natural killerccll activity is associated with severity of chronic fatigue immune dysfunction syndrome. Clin Infect Dis. 1994; 18: SI57–9.
   Google Scholar
• Morrison LJ, Bchan WH, Bchan PO. Changes in natural killer ccll phenotype in patients with postviral fatigue syndrome. Clin Exp Immunol. 1991; 83:441–6.
   Google Scholar
• Read R, Spickctt G, Harvey J, Edwards A J, Larson HE. IgGl subclass deficiency in patients with chronic fatigue syndrome. Lancet. 1988; 1:241–2.
   Google Scholar
• Komaroff Al, Geiger AM, Wormscly. IgG subclass deficiencies in chronic fatigue syndrome. Lancet 1988: 1: 1288–89
   Google Scholar
• Peterson PK, Shcpard J, Macres M, et al. A controlled trial of intravenous immunoglobulin G in chronic fatigue syndrome. Am J Med. 1990; 89: 554–60.
   Google Scholar
• Jamal G, Hansen S. Postviral fatigue syndrome: evidence for underlying organic disturbance in the muscle fibre. Eur Neurol. 1985; 29: 273–6.
   Google Scholar
• Byrne E, Trounce I, Dennett X. Chronic relapsing myalgia (? postviral): clinical, histological and biomedical siuiiics.AitstNZJMed. 1985; 15:3058.
   Google Scholar
• Precdy VR, Smith DG, Salisbury JR. Peters TJ. Biochemical and muscic studies in patients with acute onset postviral fatigue syndrome. J Clin Pathol. 1993; 46: 722–6.
   Google Scholar
• Bchan PO, Bakhcit AMO. Clinical spectrum of postviral fatigue syndrome. Br Med Bull. 1991; 47793–808.
   Google Scholar
• Bchan PO, Bchan WMH, Gow JW, Cavanagh H, Gillespie S. Enteroviruses and the postviral fatigue syndrome. In: Chronic fatigue syndrome Wiley, Chichester (Ciha foundation symposium 173) pi 46–59.
   Google Scholar
• Blalock JE. The syntax of immune-neuroendocrine communication. Immunol Today. 1994; 15504–11.
   Google Scholar
• Demitrack MA, Dale JK. Straus SEetal. Evidence for impaired activation of the hypothalamicpiluitary-adrcnal axis in patients with chronic fatigue syndrome. J Clin Endocrinol Metab 1991; 731224–34.
   Google Scholar
• Griep EN, Bocrsma JW. de Kloet R. Altered reactivity of the hypothalamic-pituitary-adrenal axis in the primary fibromyalgia syndrome. J Rheum 1993; 20: 469–74.
   Google Scholar
• Irwin M. Stress-induced immune suppression. Role of the autonomic nervous system. Ann N Y AcadSci. 1993; 697: 203–18.
   Google Scholar
• Harbu I. MS, Lightman SL. Stress and the hypothalamo-pituitary adrenal axis: acute chronic and immunological activation. J Endocrinol. 1992; 134327–39.
   Google Scholar
• Bakhcit AM. Bchan PO. Watson WS. Morion JJ. Abnormal argininc-vasopressin sccrction and water metabolism in patients with postviral fatigue syndrome. Acta Neurol Scand. 1993: 87: 234–8.
   Google Scholar
• Krusi MJP. Dale J. Straus SE. Psychiatric diagnoses in patients who have chronic fatigue syndrome. J Clin Psychiatry. 1989; 50: 53–6.
   Google Scholar
• Wcssely S, Powell R. Fatigue syndromes: a comparison of chronic “postviral” fatigue with neuromuscular and affective disorders. J Neurol Neurosurg Psychiatry. 1989; 52: 940–8.
   Google Scholar
• Tacrk G, Gnaw W. A psychodynamic view of the chronic fatigue syndrome, the role of objcct relations in etiology and treatment. Gen Hosp Psychiatry. 1994; 16: 319–25.
   Google Scholar
• Komaroff AL. Straus SE. Gantz NM, Jones JF. The chronic fatigue syndrome. Ann Intern Med. 1989; 110:407–18.
   Google Scholar
• Schlucdeberg A, Straus SE, Peterson Pet al. Chronic fatigue syndrome research. Definition and medical outcome assessment. Ann Intern Med. 1992; 117: 325–31
   Google Scholar
• Lane JL, Manu P, Matthews DA. Depression and somatization in the chronic fatigue syndrome. Am J Med. 1991;91:335–44.
   Google Scholar
• Katon W, Russo J. Chronic fatigue syndrome criteria. A critique of the requirement for multiple physical complaints. Arch Intern Med. 1992; 1604–09.
   Google Scholar
• Bakheit AM, Behan PO. Dinan TG. el al. Possible upregulation of hypothalamic 5-hydroxytrypiamine receptors in patients with postviral fatigue syndrome. Br Med J. 1992; 304: 1010–12.
   Google Scholar
• Brook MG, Bannister B A, Weir WRC. Inicrfcrona therapy for patients with chronic fatigue syndrome. J Infect Dis. 1993; 168: 791–2.
   Google Scholar
• Straus SE, Dale JK, Tobi el al. Acyclovir treatment of the chronic fatigue syndrome. Lack of efficacy in a placebo-controlled trial. N Engl J Med. 1988; 26: 1692–98.
   Google Scholar
• Lloyd A, Hickie I, Wakefield D. Boughlon C. Dwyer J. A double-blind placebo-controlled trial of intravenous immunoglobulin therapy in patientswith chronic fatigue syndrome. Am J Med. 1990; 89:561–8
   Google Scholar
• ShimolaloT, Iwaia M, Kawada H.TamuraN. Human immunoglobulin preparation for intravenous use induces elevations of cellular cyclic adenosine 3’5’-monophosphatc levels, resulting in suppression of tuin or necrosis factor alpha and interlcukin-1 production. Immunology. 1991;72:497–52.
   Google Scholar
• Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991; 337: 757–60.
   Google Scholar
• Wilson A. Hickie I, Lloyd A, Wakefield D. The treatment of chronic fatigue syndrome: science and speculation. Am J Med. 1994; 96: 544–50
   Google Scholar
• Manu P, Lane TJ, Matthews DA. The frequency of the chronic fatigue syndrome in patients with symptoms of persistant fatigue. Ann Intern Med. 1988; 109: 534–40.
   Google Scholar
• Butler S, ChalderT, Ron M et al. Cognitive behavior therapy in chronic fatigue syndrome. J Neurol Neurosurg Psychiatry. 1991; 54: 153–8.
   Google Scholar
• Lloyd AR, Hickie I, Brockman A. et al. Immunologic and psychological therapy for patients with chronic fatigue syndrome: a double-blind, placebo-controlled trial. Am J Med. 1993; 94: 197–203.
   Google Scholar