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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 71, 2016 - Issue 4
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Original Paper

The association of neutrophil/lymphocyte ratio and platelet/lymphocyte ratio with clinical outcomes in geriatric patients with stage 3–5 chronic kidney disease

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References

  • Glassock RJ, Rule AD. The implications of anatomical and functional changes of the aging kidney: with an emphasis on the glomeruli. Kidney Int. 2012;82:270–7.10.1038/ki.2012.65
  • KDIGO. Clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2012;2013(3):1.
  • Jager KJ, van Dijk PC, Dekker FW, Stengel B, Simpson K, Briggs JD. The epidemic of aging in renal replacement therapy: an update on elderly patients and their outcomes. Clin Nephrol. 2003;60:352–60.10.5414/CNP60352
  • Canaud B, Tong L, Tentori F, Akiba T, Karaboyas A, Gillespie B, et al. Clinical practices and outcomes in elderly hemodialysis patients: results from the dialysis outcomes and practice patterns study (DOPPS). Clin J Am Soc Nephrol. 2011;6:1651–62.10.2215/CJN.03530410
  • Cohen LM, Ruthazer R, Moss AH, Germain MJ. Predicting six-month mortality for patients who are on maintenance hemodialysis. Clin J Am Soc Nephrol. 2010;5:72–9.10.2215/CJN.03860609
  • Berger JR, Hedayati SS. Renal replacement therapy in the elderly population. Clin J Am Soc Nephrol. 2012;7:1039–46.10.2215/CJN.10411011
  • Azab B, Zaher M, Weiserbs KF, Torbey E, Lacossiere K, Gaddam S, et al. Usefulness of neutrophil to lymphocyte ratio in predicting short- and long-term mortality after non–ST-elevation myocardial ınfarction. Am J Cardiol. 2010;106:470–6.10.1016/j.amjcard.2010.03.062
  • Kalay N, Dogdu O, Koc F, et al. Hematologic parameters and angiographic progression of coronary atherosclerosis. Angiology. 2012;63:213–7.10.1177/0003319711412763
  • Xiao WK, Chen D, Li SQ, Fu SJ, Peng BG, Liang LJ. Prognostic significance of neutrophil-lymphocyte ratio in hepatocellular carcinoma: a meta-analysis. BMC Cancer. 2014;14:1–10.10.1186/1471-2407-14-117
  • Wei Y, Jiang YZ, Qian WH. Prognostic role of NLR in urinary cancers: a meta-analysis. PLoS One. 2014;9(3):e92079.10.1371/journal.pone.0092079
  • Iijima R, Ndrepepa G, Mehilli J, Bruskina O, Schulz S, Schömig A, et al. Relationship between platelet count and 30-day clinical outcomes after percutaneous coronary interventions. Pooled analysis of four ISAR trials. Thromb Haemost. 2007;98:852–7.
  • Smith RA, Bosonnet L, Raraty M, Sutton R, Neoptolemos JP, Campbell F, et al. Preoperative platelet lymphocyte ratio is an independent significant prognostic marker in resected pancreatic ductal adenocarcinoma. Am J Surg. 2009;197:466–72.10.1016/j.amjsurg.2007.12.057
  • Fried L, Solomon C, Shlipak M, Seliger S, Stehman-Breen C, Bleyer AJ, et al. Inflammatory and prothrombotic markers and the progression of renal disease in elderly ındividuals. J Am Soc Nephrol. 2004;15:3184–91.10.1097/01.ASN.0000146422.45434.35
  • Okyay GU, Inal S, Oneç K, Er RE, Paşaoğlu O, Paşaoğlu H, et al. Neutrophil to lymphocyte ratio in evaluation of ınflammation in patients with chronic kidney disease. Ren Fail. 2013;35:29–36.10.3109/0886022X.2012.734429
  • Kocyigit I, Eroglu E, Unal A, Sipahioglu MH, Tokgoz B, Oymak O, et al. Role of neutrophil/lymphocyte ratio in prediction of disease progression in patients with stage-4 chronic kidney disease. J Nephrol. 2013;26:358–65.10.5301/jn.5000152
  • Binnetoğlu E, Şengül E, Halhallı G, Dindar S, Şen H. Is neutrophil lymphocyte ratio an ındicator for proteinuria in chronic kidney disease? J Clin Lab Anal. 2014;28:487–92.10.1002/jcla.2014.28.issue-6
  • An X, Mao HP, Wei X, Chen JH, Yang X, Li ZB, et al. Elevated neutrophil to lymphocyte ratio predicts overall and cardiovascular mortality in maintenance peritoneal dialysis patients. Int Urol Nephrol. 2012;44:1521–8.10.1007/s11255-012-0130-3
  • Franceschi C. Inflammaging as a major characteristic of old people: can ıt be prevented or cured? Nutr Rev. 2007;65:173–6.10.1301/nr.2007.dec.S173-S176
  • Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038–47.10.1001/jama.298.17.2038
  • James MT, Hemmelgarn BR, Tonelli M. Early recognition and prevention of chronic kidney disease. Lancet. 2010;375:1296–309.10.1016/S0140-6736(09)62004-3
  • Tonelli M, Sacks F, Pfeffer M, Jhangri GS, Curhan G. Biomarkers of inflammation and progression of chronickidney disease. Kidney Int. 2005;68:237–45.10.1111/j.1523-1755.2005.00398.x
  • Nikolova-Karakashian M, Karakashian A, Rutkute K. Role of neutral sphingomyelinases in ageing and inflammation. Subcell Biochem. 2008;49:469–86.10.1007/978-1-4020-8831-5
  • Kim KI, Lee J, Heo NJ, Kim S, Chin HJ, Na KY, et al. Differential white blood cell count and all-cause mortality in the Korean elderly. Exp Gerontol. 2013;48:103–8.10.1016/j.exger.2012.11.016
  • Vaughan-Shaw PG, Rees JR, King AT. Neutrophil lymphocyte ratio in outcome prediction after emergency abdominal surgery in the elderly. Int J Surg. 2012;10:157–62.10.1016/j.ijsu.2012.02.010
  • Forget P, Moreau N, Engel H, Cornu O, Boland B, De Kock M, et al. The neutrophil-to-lymphocyte ratio (NLR) after surgery for hip fracture (HF). Arch Gerontol Geriatr. 2015;60:366–71.10.1016/j.archger.2014.11.008
  • Franchini M. Hemostasis and aging. Crit Rev Oncol Hematol. 2006;60:144–51.10.1016/j.critrevonc.2006.06.004
  • Jalal DI, Chonchol M, Targher G. Disorders of hemostasis associated with chronic kidney disease. Semin Thromb Hemost. 2010;36:34–40.10.1055/s-0030-1248722
  • Turkmen K, Erdur FM, Ozcicek F, Ozcicek A, Akbas EM, Ozbicer A, et al. Platelet-to-lymphocyte ratio better predicts inflammation than neutrophil-to-lymphocyte ratio in end-stage renal disease patients. Hemodial Int. 2013;17:391–6.10.1111/hdi.2013.17.issue-3
  • Tejwani V, Qian Q. Calcium regulation and bone mineral metabolism in elderly patients with chronic kidney disease. Nutrients. 2013;5:1913–36.10.3390/nu5061913
  • Sigrist MK, Taal MW, Bungay P, McIntyre CW. Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney disease. Clin J Am Soc Nephrol. 2007;2:1241–8.10.2215/CJN.02190507

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