Publication Cover
Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 71, 2016 - Issue 6
711
Views
10
CrossRef citations to date
0
Altmetric
Congress Paper

Whipple’s disease

References

  • Marth T, Moos V, Müller C, Biagi F, Schneider T. Tropheryma whipplei infection and Whipple’s disease. Lancet Infect Dis. 2016;16:e13–e22.10.1016/S1473-3099(15)00537-X
  • Fenollar F, Puéchal X, Raoult D. Whipple’s disease. N Engl J Med. 2007;356:55–66.10.1056/NEJMra062477
  • Wilson KH, Blitchington R, Frothingham R, Wilson JA. Phylogeny of the Whipple’s-disease-associated bacterium. Lancet. 1991;338:474–5.10.1016/0140-6736(91)90545-Z
  • Relman DA, Schmidt TM, MacDermott RP, Falkow S. Identification of the uncultured bacillus of Whipple’s disease. N Engl J Med. 1992;327:293–301.10.1056/NEJM199207303270501
  • Schoedon G, Goldenberger D, Forrer R, Gunz A, Dutly F, Höchli M, et al. Deactivation of macrophages with interleukin‐4 is the key to the isolation of Tropheryma whippelii. J Infect Dis. 1997;176:672–7.10.1086/jid.1997.176.issue-3
  • Raoult D, Birg ML, Scola B, Fournier PE,Enea M, et al. Cultivation of the bacillus of Whipple’s disease. N Engl J Med. 2000;342:620–5.10.1056/NEJM200003023420903
  • Bentley SD, Maiwald M, Murphy LD, Pallen MJ, Yeats CA, Dover LG, et al. Sequencing and analysis of the genome of the Whipple’s disease bacterium Tropheryma whipplei. Lancet. 2003;361:637–644.10.1016/S0140-6736(03)12597-4
  • Puéchal X. Whipple disease and arthritis. Curr Opin Rheumatol. 2001;13:74–9.10.1097/00002281-200101000-00012
  • Mahnel R, Kalt A, Ring S, Stallmach A, Strober W, Marth T. Immunosuppressive therapy in Whipple’s disease patients is associated with the appearance of gastrointestinal manifestations. Am J Gastroenterol. 2005;100:1167–73.10.1111/ajg.2005.100.issue-5
  • Marth T. Systematic review: Whipple’s disease (Tropheryma whipplei infection) and its unmasking by tumour necrosis factor inhibitors. Aliment Pharmacol Ther. 2015;41:709–24.10.1111/apt.2015.41.issue-8
  • Compain C, Sacre K, Puéchal X, Klein I, Vital-Durand D, Houeto JL, et al. Central nervous system involvement in Whipple disease. Medicine. 2013;92:324–30.10.1097/MD.0000000000000010
  • La Scola B, Fenollar F, Fournier PE, Altwegg M, Mallet MN, Raoult D. Description of Tropheryma whipplei gen.nov., sp.nov., the Whipple’s disease bacillus. Int J Syst Evol Microbiol. 2001;51:1471–9.10.1099/00207713-51-4-1471
  • Fenollar F, Trani M, Davoust B, Salle B, Birg ML, Rolain JM, et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. J Infect Dis. 2008;197:880–7.10.1086/587999
  • Moter A, Schmiedel D, Petrich A, Wiessner A, Kikhney J, Schneider T, et al. Validation of an rpoB gene PCR assay for detection of Tropheryma whipplei: ten years experience in a national reference laboratory. J Clin Microbiol. 2013;51:3858–61.10.1128/JCM.01703-13
  • Marth T, Neurath M, Cuccherini BA, Strober W. Defects of monocyte interleukin 12 production and humoral immunity in Whipple’s disease. Gastroenterology. 1997;113:442–8.10.1053/gast.1997.v113.pm9247462
  • Moos V, Schmidt C, Geelhaar A, Kunkel D, Allers K, Schinnerling K, et al. Impaired Immune functions of monocytes and macrophages in Whipple’s disease. Gastroenterology. 2010;138:210–20.10.1053/j.gastro.2009.07.066
  • Marth T, Kleen N, Stallmach A, Ring S, Aziz S, Schmidt C, Strober W, et al. Dysregulated peripheral and mucosal Th1/Th2 response in Whipple’s disease. Gastroenterology. 2002;123:1468–77.10.1053/gast.2002.36583
  • Desnues B, Lepidi H, Raoult D, Mege JL. Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages. J Infect Dis. 2005;192:1642–6.10.1086/jid.2005.192.issue-9
  • Schinnerling K, Geelhaar-Karsch A, Allers K, Friebel J, Conrad K, Loddenkemper C, et al. Role of dendritic cells in the pathogenesis of Whipple’s disease. Infect Immun. 2015;83:482–91.10.1128/IAI.02463-14
  • Lagier JC, Lepidi H, Raoult D, Fenollar F. Systemic Tropheryma whipplei. Medicine. 2010;89:337–45.10.1097/MD.0b013e3181f204a8
  • Keinath RD, Merrell DE, Vlietstra R, Dobbins WO III. Antibiotic treatment and relapse in Whipple’s disease. Gastroenterology. 1985;88:1867–73.10.1016/0016-5085(85)90012-5
  • Feurle GE, Moos V, Schinnerling K, Geelhaar A, Allers K, Biagi F, et al. The immune reconstitution inflammatory syndrome in Whipple disease. Ann Int Med. 2010;153:710–7.10.7326/0003-4819-153-11-201012070-00004
  • Geissdorfer W, Moos V, Moter A, Loddenkemper C, Jansen A, Tandler R, et al. High frequency of Tropheryma whipplei in culture-negative endocarditis. J Clin Microbiol. 2012;50:216–22.10.1128/JCM.05531-11
  • Raoult D, Fenollar F, Rolain JM, Minodier P, Bosdure E, Li W, et al. Tropheryma whipplei in children with gastroenteritis. Emerg Infect Dis. 2010;16:776–82.10.3201/eid1605.091801
  • Keita AK, Dubot-Pérès A, Phommasone K, Sibounheuang B, Vongsouvath M, Mayxay M, et al. High prevalence of Tropheryma whipplei in Lao kindergarten children. PLoS Negl Trop Dis. 2015;9:e0003538.10.1371/journal.pntd.0003538
  • Schöniger-Hekele M, Petermann D, Weber B, Müller C. Tropheryma whipplei in the environment: survey of sewage plant influxes and sewage plant workers. Appl Environ Microbiol. 2007;73:2033–5.10.1128/AEM.02335-06
  • Cohen AS, Schimmel EM, Holt PR, Isselbacher KJ. Ultrastructural abnormalities in Whipple’s disease. Proc Soc Exp Biol Med. 1960;105:411–4.10.3181/00379727-105-26126
  • Dobbins WO III. Whipple’s disease. Springfield (IL): Charles C Thomas; 1987.
  • Ghigo E, Capo C, Aurouze M, Tung CH, Gorvel JP, Raoult D, et al. Survival of Tropheryma whipplei, the agent of Whipple’s disease, requires phagosome acidification. Infect Immun. 2002;70:1501–6.10.1128/IAI.70.3.1501-1506.2002
  • Raoult D, Ogata H, Audic S, Robert C, Suhre K, Drancourt M, et al. Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 2003;13:1800–9.
  • Li W, Fenollar F, Rolain JM, Fournier PE, Feurle GE, Müller C, et al. Genotyping reveals a wide heterogeneity of Tropheryma whipplei. Microbiology. 2008;154:521–7.10.1099/mic.0.2007/011668-0
  • Maiwald M, Schuhmacher F, Ditton HJ, von Herbay A. Environmental occurrence of the Whipple’s disease bacterium (Tropheryma whippelii). Appl Environ Microbiol. 1998;64:760–2.
  • Keita AK, Mediannikov O, Ratmanov P, Diatta G, Bassene H, Roucher C, et al. Looking for Tropheryma whipplei source and reservoir in rural Senegal. Am J Trop Med Hyg. 2013;88:339–43.10.4269/ajtmh.2012.12-0614
  • Dutly F, Altwegg M. Whipple’s disease and ‘Tropheryma whippelii’. Clin Microbiol Rev. 2001;14:561–83.10.1128/CMR.14.3.561-583.2001
  • Gerard A, Sarrot-Reynauld F, Liozon E, Cathebras P, Besson G, Robin C, et al. Neurologic presentation of Whipple disease. Medicine. 2002;81:443–57.10.1097/00005792-200211000-00005
  • Fleming JL, Wiesner RH, Shorter RG. Whipple’s disease: clinical, biochemical, and histopathologic features and assessment of treatment in 29 patients. Mayo Clin Proc. 1988;63:539–51.10.1016/S0025-6196(12)64884-8
  • Durand DV, Lecomte C, Cathébras P, Rousset H, Godeau P. Whipple disease. Clinical review of 52 cases. The SNFMI Research Group on Whipple Disease. Société Nationale Française de Médecine Interne.10.1097/00005792-199705000-00003
  • Schnider PJ, Reisinger EC, Gerschlager W, et al. Long-term follow-up in cerebral Whipple’s disease. Eur J Gastroenterol Hepatol. 1996;8:899–903.
  • Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple’s disease. Gastroenterology. 2010;138:478–86.10.1053/j.gastro.2009.10.041
  • Fenollar F, Celard M, Lagier JC, et al. Tropheryma whipplei endocarditis. Emerg Inf Dis. 2013;19:1721–30.
  • Lozupone C, Cota-Gomez A, Palmer BE, et al. Widespread colonization of the lung by Tropheryma whipplei in HIV infection. Am J Respir Crit Care Med. 2013;187:1110–7.10.1164/rccm.201211-2145OC
  • Bousbia S, Papazian L, Auffray JP, Fenollar F, Martin C, Li W, et al. Tropheryma whipplei in patients with pneumonia. Emerg Infect Dis. 2010;16:258–63.10.3201/eid1602.090610
  • Ehrbar HU, Bauerfeind P, Dutly F, Koelz HR, Altwegg M. PCR-positive tests for Tropheryma whippelii in patients without Whipple’s disease. Lancet. 1999;353:2214.10.1016/S0140-6736(99)01776-6
  • Marth T. Complicated Whipple’s disease and endocarditis following tumor necrosis factor inhibitors. World J Cardiol. 2014;6:1278–84.10.4330/wjc.v6.i12.1278
  • Biagi F, Trotta L, Di Stefano M, Balduzzi D, Marchese A, Vattiato C, et al. Previous immunosuppressive therapy is a risk factor for immune reconstitution inflammatory syndrome in Whipple’s disease. Dig Liver Dis. 2012;44:880–2.10.1016/j.dld.2012.05.008
  • Meunier M, Puechal X, Hoppé E, Soubrier M, Dieudé P, Berthelot JM, et al. Rheumatic and musculoskeletal features of Whipple disease: a report of 29 cases. J Rheumatol. 2013;40:2061–6.10.3899/jrheum.130328
  • Martinetti M, Biagi F, Badulli C, Feurle GE, Müller C, Moos V, et al. The HLA alleles DRB1*13 and DQB1*06 Are associated to Whipple’s disease. Gastroenterology. 2009;136:2289–94.10.1053/j.gastro.2009.01.051
  • Feurle GE, Moos V, Bläker H, Loddenkemper C, Moter A, Stroux A, et al. Intravenous ceftriaxone, followed by 12 or three months of oral treatment with trimethoprim-sulfamethoxazole in Whipple’s disease. J Infect. 2013;66:263–70.10.1016/j.jinf.2012.12.004
  • Lagier JC, Fenollar F, Lepidi H, Giorgi R, Million M, Raoult D. Treatment of classic Whipple’s disease: from in vitro results to clinical outcome. J Antimicrob Chemother. 2014;69:219–27.10.1093/jac/dkt310
  • Fenollar F, Rolain JM, Alric L, Papo T, Chauveheid MP, van de Beek D, et al. Resistance to trimethoprim/sulfamethoxazole and Tropheryma whipplei. Int J Antimicrob Agents. 2009;34:255–9.10.1016/j.ijantimicag.2009.02.014
  • Lagier JC, Fenollar F, Lepidi H, Raoult D. Evidence of lifetime susceptibility to Tropheryma whipplei in patients with Whipple’s disease. J Antimicr Chemother. 2011;66:1188–9.10.1093/jac/dkr032

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.