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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 73, 2018 - Issue 6
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Case Report

Flucloxacillin-induced hypokalaemia: a case report

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References

  • Valour F, Karsenty J, Bouaziz A, et al. Antimicrobial-related severe adverse events during treatment of bone and joint infection due to methicillin-susceptible staphylococcus aureus. Antimicrob Agents Chemother. 2014;58(2):746–755.10.1128/AAC.02032-13
  • Johnson D, Kay T, Hawley C. Severe hypokalaemia secondary to dicloxacillin. Intern Med J. 2002;32(7):357–358.10.1046/j.1445-5994.2002.00243.x
  • Zietse R, Zoutendijk R, Hoorn EJ. Fluid, electrolyte and acid–base disorders associated with antibiotic therapy. Nat Rev Nephrol. 2009;5(4):193–202.10.1038/nrneph.2009.17
  • Hoorn EJ, Zietse R. Severe hypokalaemia caused by flucloxacillin. J Antimicrob Chemother. 2008 Jun;61(6):1396–1398.10.1093/jac/dkn117
  • Hussain S, Syed S, Baloch K. Electrolytes imbalance: a rare side effect of piperacillin/tazobactam therapy. J Coll Physicians Surg Pak. 2010;20(6):419–420.
  • Landersdorfer CB, Kirkpatrick CM, Kinzig-Schippers M, et al. Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin. Antimicrob Agents Chemother. 2007 Sep;51(9):3290–3297.10.1128/AAC.01410-06
  • Landersdorfer CB, Kirkpatrick CM, Kinzig M, et al. Inhibition of flucloxacillin tubular renal secretion by piperacillin. Br J Clin Pharmacol. 2008;66(5):648–659.
  • Brunner FP, Frick PG. Hypokalaemia, metabolic alkalosis, and hypernatraemia due to “massive” sodium penicillin therapy. Br Med J. 1968 Nov 30;4(5630):550–552.10.1136/bmj.4.5630.550
  • Pearce D, Soundararajan R, Trimpert C, et al. Collecting duct principal cell transport processes and their regulation. Clin J Am Soc Nephrol. 2015 Jan 7;10(1):135–146.10.2215/CJN.05760513
  • Roy A, Al-bataineh MM, Pastor-Soler NM. Collecting duct intercalated cell function and regulation. Clin J Am Soc Nephrol. 2015 Feb 6;10(2):305–324.10.2215/CJN.08880914
  • Grimm PR, Sansom SC. BK channels in the kidney. Curr Opin Nephrol Hypertens. 2007 Sep;16(5):430–436.10.1097/MNH.0b013e32826fbc7d
  • Zaki SA, Lad V. Piperacillin-tazobactam-induced hypokalemia and metabolic alkalosis. Indian J Pharmacol. 2011 Sep;43(5):609–610.10.4103/0253-7613.84986
  • Rieg T, Vallon V, Sausbier M, et al. The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion. Kidney Int. 2007;72(5):566–573.10.1038/sj.ki.5002369
  • Squires RD, Huth EJ. Experimental potassium depletion in normal human subjects. I. Relation of ionic intakes to the renal conservation of potassium. J Clin Invest. 1959;38(7):1134–1148.10.1172/JCI103890
  • Groeneveld JH, Sijpkens YW, Lin SH, et al. An approach to the patient with severe hypokalaemia: the potassium quiz. QJM. 2005 Apr;98(4):305–16.10.1093/qjmed/hci046
  • McMahon GT, Blake MA, Wu C. Case 1-2010: a 75-year-old man with hypertension, hyperglycemia, and edema. N Engl J Med. 2010;362(2):156–166.10.1056/NEJMcpc0905546

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