Febrile neutropenia induces changes in insulin sensitivity similar to obesity

References

• Gunalp M, Koyunoglu M, Gurler S, et al. Independent factors for prediction of poor outcomes in patients with febrile neutropenia. Med Sci Monit 2014;20:1826–1832.
   PubMed Web of Science ®Google Scholar
• Ali NA, O’Brien JM Jr, Blum W, et al. Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality. Cancer 2007;110(1):96–102.
   PubMed Web of Science ®Google Scholar
• Klastersky J, Paesmans M, Rubenstein EB, et al. The multinational association for supportive care in cancer risk index: a multinational scoring system for identifying low-risk febrile neutropenic cancer patients. J Clin Oncol 2000;18(16):3038–3051.
   PubMed Web of Science ®Google Scholar
• Soysal DE, Karakus V, Seren AR, et al. Evaluaton of transient hyperglycemia in non-diabetic patients with febrile neutropenia. Eur J Int Med 2012;23:342–346.
   PubMed Web of Science ®Google Scholar
• Klastersky J, de Naurois J, Rolston K, et al. Management of febrile neutropaenia: ESMO clinical practice guidelines. Ann Oncol 2016;27(suppl5):v111–v118.
   PubMedGoogle Scholar
• Povoa P, Ces Souza-Dantas V, Soares M, et al. C-reactive protein in critically ill cancer patient with sepsis: influence of neutropenia. Crit Care 2011;15:R129.
   PubMed Web of Science ®Google Scholar
• Simon L, Gauvin F, Amre DK, et al. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systemic review and meta-analysis. Clin Infect Dis 2004;39:206–217.
   PubMed Web of Science ®Google Scholar
• Carmona-Bayonas A, Font C, Ayala de la Pena F. Stress-induced hyperglycemia is a valuable biomarker in febrile neutropenia. Rev Bras Hematol Hemoter 2013;35(1):3–17.
   PubMedGoogle Scholar
• Sonabend RY, McKay SV, Okcu MF, et al. Hyperglycemia during induction therapy is associated with increased infectious complications in childhood acute lymphocytic leukemia. Pediatr Blood Cancer 2008;51:387–392.
   PubMed Web of Science ®Google Scholar
• Li L, Thompson LH, Zhao L, et al. Tissue specific difference in the molecular mechanisms for the development of acute insulin resistance following injury. Endocrinology 2009;150:24–32.
   PubMed Web of Science ®Google Scholar
• Li L, Messina JL Acute insulin resistance following injury. Trends Endocrinol Metab 2009;20(9):429–435.
   PubMed Web of Science ®Google Scholar
• Akira S, Uematsu S, Takeuchi O Pathogen recognition and innate immunity. Cell 2006;124:783–801.
   PubMed Web of Science ®Google Scholar
• Piccinini AM, Midwood KS DAMPening inflammation by modulating TLR signaling. Mediators Inflamm 2010;2010:p1.
   Web of Science ®Google Scholar
• Minicassamy S, Pulendran B Modulation of adaptive immunity with Toll-like receptors. Semin Immunol 2009;21:185–193.
   PubMed Web of Science ®Google Scholar
• Takeda K, Akira S Toll-like receptors in innate immunity. Internat Immunol 2005;17(1):1–14.
   PubMed Web of Science ®Google Scholar
• Takeuchi O, Akira S Pattern recognition receptors and inflammation. Cell 2010;140:805–820.
   PubMed Web of Science ®Google Scholar
• Kunz-Ebrecht SR, Mohamed-Ali V, Feldman PJ, et al. Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokines. Brain Behav Immun 2003;17:373–383.
   PubMed Web of Science ®Google Scholar
• Kovalaske MA, Gandhi GY Glycemic control in the medical intensive care unit. J Diabetes Sci Technol 2009;3(6):1330–1341.
   PubMedGoogle Scholar
• Hotamisligil GS Inflammation and metabolic disorders. Nature 2006;444(7121):860–867.
   PubMed Web of Science ®Google Scholar
• Lumeng CN, Saltiel AR Inflammatory links between obesity and metabolic disease. J Clin Invest 2011;121(6):2111–2117.
   PubMed Web of Science ®Google Scholar
• Guilherme A, Virbasius JV, Puri V, et al. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev 2008;9:367–377.
   Google Scholar
• Dandona P, Aljada A, Bandyopadhyay A Inflammation: the link between insulin resistance, obesity and diabetes. Trends in Immunol 2004;25(1):4–7.
   PubMed Web of Science ®Google Scholar
• Bennett JM, Catovsky D, Daniel MT, et al. Proposals for the classification of the acute leukaemias. French–American–British (FAB) co-operative group. Br J Haematol 1976;33:219–228.
   Google Scholar
• Baden LR, Swaminathan S, Angarone M, et al. Prevention and treatment of cancer-related infections, version 1.2016.NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 2016;14(7):882–913.
   PubMed Web of Science ®Google Scholar
• Carmona-Bayonas A, Gomez J, Gonzales-Billalabelitia E, et al. Prognostic evaluation of febrile neutropenia in apparently stable adult cancer patients. Br J Cancer. 2011;105(5):612–617.
   PubMed Web of Science ®Google Scholar
• Fuji S, Kim SW, Mori S, et al. Hyperglycemia during the neutropenic period is associated with a poor outcome in patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation. Transplantation 2007;84:814–820.
   PubMed Web of Science ®Google Scholar
• Matias CN, Lima V, Teixeira HM, et al. Hyperglycemia increased the complicated infection and mortality rates during induction therapy in adult acute leukemia patients. Rev Bras Hematol Hemoter 2013;35(1):39–43.
   PubMedGoogle Scholar
• Roberson JR, Spraker HL, Shelso J, et al. Clinical consequences of hyperglycemia during remission induction therapy for pediatric acute lymphoblastic leukemia. Leukemia 2009;23:245–250.
   PubMed Web of Science ®Google Scholar
• Derr RL, Hsiao VC, Saudek CD Antecedent hyperglycemia is associated with an increased risk of neutropenic infections during bone marrow transplantation. Diabetes Care 2008;31(10):1972–1977.
   PubMed Web of Science ®Google Scholar
• American Diabetes Association,Standards of medical care in diabetes – 2016: summary of revision. 2. Classification and diagnosis of diabetes. Diabetes Care 2016;39(Suppl.1):S13–S22. doi: 10.2337/dc16-S004.
   PubMed Web of Science ®Google Scholar
• Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412–419.
   PubMed Web of Science ®Google Scholar
• Ascaso JF, Pardo S, Real JT, et al. Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism. Diab Care 2003;26:3320–3325.
   PubMed Web of Science ®Google Scholar
• Bonizzoli M, Zagli G, Lazzeri C, et al. Early insulin resistance in severe trauma without head injury as outcome predictor? A prospective monocentric pilot study. Scand J Trauma Res Emerg Med 2012;20:69.
   PubMed Web of Science ®Google Scholar
• Refaie W, Elewa A Admission insulin resistance index in non diabetic patients with acute coronary syndrome; clinical and angiographic features. Egypt Heart J 2013;65:301–305.
   Google Scholar
• Marik PE, Bellomo R Stress hyperglycemia: an essential survival response! Crit Care 2013;17:305.
   PubMed Web of Science ®Google Scholar
• Pourfarzam M, Zadhoush F, Sadeghi M He difference in correlation between insulin resistance index and chronic inflammation in type 2 diabetes with and without metabolic syndrome. Adv Biomed Res 2016;5:153.
   PubMedGoogle Scholar
• Carmona-Bayonas A, Jimenez-Fonseca P, Echaburu JV, et al. Prediction of serious complications in patients with seemingly stable febrile neutropenia: validation of the clinical index of stable febrile neutropenia in a prospective cohort of patients from FINITE study. J Clin Oncol 2015;33:465–471
   PubMed Web of Science ®Google Scholar