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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 76, 2021 - Issue 2
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Case Report

Granulomatous amoebic encephalitis caused by Acanthamoeba in a patient with AIDS: a challenging diagnosis

Hsien Lee Laua Departments of Neurology, Miller School of Medicine University of Miami, Miami, FL, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-6655-9507
ORCID Icon,
Daniela F. De Lima Corvinob Infectious Disease, Miller School of Medicine University of Miami, Miami, FL, USA
,
Francisco M. Guerra Jr.b Infectious Disease, Miller School of Medicine University of Miami, Miami, FL, USAORCID Iconhttps://orcid.org/0000-0001-7865-7350
ORCID Icon,
Amer M. Malika Departments of Neurology, Miller School of Medicine University of Miami, Miami, FL, USA
,
Paola N. Lichtenbergera Departments of Neurology, Miller School of Medicine University of Miami, Miami, FL, USA
,
Sakir H. Gultekinc Pathology, Miller School of Medicine University of Miami, Miami, FL, USA
,
Jana M. Ritterd Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
,
Shantanu Roye Waterborne Disease Prevention Branch, Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
,
Ibne Karim M. Alie Waterborne Disease Prevention Branch, Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
,
Jennifer R. Copee Waterborne Disease Prevention Branch, Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
,
M. Judith D. Postf Pathology and Radiology, Miller School of Medicine University of Miami, Miami, FL, USAORCID Iconhttps://orcid.org/0000-0003-4759-390X
ORCID Icon &
Jose A. Gonzales Zamorab Infectious Disease, Miller School of Medicine University of Miami, Miami, FL, USAORCID Iconhttps://orcid.org/0000-0002-2768-9712
ORCID Icon show all
Pages 127-131 | Published online: 27 Aug 2019

References

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  • Duggal MS, Rongpharpi SR, Duggal AK, et al. Role of Acanthamoeba in granulomatous encephalitis: a review [review]. J Infect Dis Immune Ther. 2016;1(1):1.
  • Schuster FL, Honarmand S, Visvesvara GS, et al. Detection of antibodies against free-living amoebae Balamuthia mandrillaris and Acanthamoeba species in a population of patients with encephalitis. Clin Infect Dis. 2006 May 1;42(9):1260–1265.
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  • Qvarnstrom Y, Visvesvara GS, Sriram R, et al. Multiplex real-time PCR assay for simultaneous detection of Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri. J Clin Microbiol. 2006 Oct;44(10):3589–3595.
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  • Kulsoom H, Baig AM, Siddiqui R, et al. Combined drug therapy in the management of granulomatous amoebic encephalitis due to Acanthamoeba spp., and Balamuthia mandrillaris. Exp Parasitol. 2014 Nov;145(Suppl):S115–20.
  • Centers for Disease C, Prevention. Investigational drug available directly from CDC for the treatment of infections with free-living amebae. MMWR Morb Mortal Wkly Rep. 2013 Aug 23;62(33):666.
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