Association between admission biomarkers and clinical outcome in older adults diagnosed with an infection in the emergency department

References

• Neeser O, Branche A, Mueller B, et al. How to: implement procalcitonin testing in my practice. Clin Microbiol Infect. 2019;25(10):1226–1230.
   PubMed Web of Science ®Google Scholar
• Karakioulaki M, Stolz D. Biomarkers in pneumonia – beyond procalcitonin. Int J Mol Sci. 2019;20(8):2004.
   PubMed Web of Science ®Google Scholar
• Sager R, Kutz A, Mueller B, et al. Procalcitonin-guided diagnosis and antibiotic stewardship revisited. BMC Med. 2017;15(1):15.
   PubMed Web of Science ®Google Scholar
• Simon L, Gauvin F, Amre DK, et al. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis. 2004;39(2):206–217.
   PubMed Web of Science ®Google Scholar
• Koozi H, Lengquist M, Frigyesi A. C-reactive protein as a prognostic factor in intensive care admissions for sepsis: a Swedish multicenter study. J Crit Care. 2020;56:73–79.
   PubMed Web of Science ®Google Scholar
• Lee S-H, Chan R-C, J-Y W, et al. Diagnostic value of procalcitonin for bacterial infection in elderly patients – a systemic review and meta-analysis. Int J Clin Pract. 2013;67(12):1350–1357.
   PubMed Web of Science ®Google Scholar
• Porfyridis I, Georgiadis G, Vogazianos P, et al. C-reactive protein, procalcitonin, clinical pulmonary infection score, and pneumonia severity scores in nursing home acquired pneumonia. Respir Care. 2014;59(4):574–581.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang S, Li L, et al. The usefulness of serum procalcitonin, C-reactive protein, soluble triggering receptor expressed on myeloid cells 1 and clinical pulmonary infection score for evaluation of severity and prognostic of community-acquired pneumonia in elderly patients. Arch Gerontol Geriatr. 2019;80:53–57.
   PubMed Web of Science ®Google Scholar
• Steichen O, Bouvard E, Grateau G, et al. Diagnostic value of procalcitonin in acutely hospitalized elderly patients. Eur J Clin Microbiol Infect Dis. 2009;28(12):1471–1476.
   PubMed Web of Science ®Google Scholar
• Akagi T, Nagata N, Miyazaki H, et al. Procalcitonin is not an independent predictor of 30-day mortality, albeit predicts pneumonia severity in patients with pneumonia acquired outside the hospital. BMC Geriatr. 2019;19(1):3.
   PubMedGoogle Scholar
• Chenevier-Gobeaux C, Trabattoni E, Elfassy Y, et al. Decisional procalcitonin thresholds are not adapted to elderly patients admitted to the emergency room. Biomarkers. 2012;17(5):477–481.
   PubMed Web of Science ®Google Scholar
• Taboulet P, Moreira V, Haas L, et al. Triage with the French emergency nurses classification in hospital scale: reliability and validity. Eur J Emerg Med. 2009;16(2):61–67.
   PubMed Web of Science ®Google Scholar
• Shankar-Hari M, Phillips GS, Levy ML, et al. Developing a new definition and assessing new clinical criteria for septic shock: for the third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA. 2016;315(8):775.
   PubMed Web of Science ®Google Scholar
• Stucker F, Herrmann F, Graf J-D, et al. Procalcitonin and infection in elderly patients: procalcitonin in older people. J Am Geriatr Soc. 2005;53(8):1392–1395.
   PubMed Web of Science ®Google Scholar
• Lai -C-C, Chen S-Y, Wang C-Y, et al. Diagnostic value of procalcitonin for bacterial infection in elderly patients in the emergency department. J Am Geriatr Soc. 2010;58(3):518–522.
   PubMed Web of Science ®Google Scholar
• Kim JH, Seo JW, Mok JH, et al. Usefulness of plasma procalcitonin to predict severity in elderly patients with community-acquired pneumonia. Tuberc Respir Dis. 2013;74(5):207.
   PubMedGoogle Scholar
• Lee WJ, Woo SH, Kim DH, et al. Are prognostic scores and biomarkers such as procalcitonin the appropriate prognostic precursors for elderly patients with sepsis in the emergency department? Aging Clin Exp Res. 2016;28(5):917–924.
   PubMed Web of Science ®Google Scholar
• Jaramillo GD, Pinilla MI. Quick sequential organ failure assessment, sequential organ failure assessment, and procalcitonin for early diagnosis and prediction of death in elderly patients with suspicion of sepsis in the emergency department, based on sepsis-3 definition. Gerontology. 2022;68(2):171–180.
   PubMed Web of Science ®Google Scholar
• Pirneskoski J, Lääperi M, Kuisma M, et al. Ability of prehospital NEWS to predict 1-day and 7-day mortality is reduced in older adult patients. Emerg Med J. 2021;38(12):913–918.
   PubMed Web of Science ®Google Scholar
• Sadighi Akha AA. Aging and the immune system: an overview. J Immunol Methods. 2018;463:21–26.
   PubMed Web of Science ®Google Scholar
• Franceschi C, Bonafè M, Valensin S, et al. Inflammaging: an evolutionary perspective on immunosenescence. Ann N Y Acad Sci. 2006;908(1):244–254.
   Google Scholar
• Ray D, Yung R. Immune senescence, epigenetics and autoimmunity. Clin Immunol. 2018;196:59–63.
   PubMed Web of Science ®Google Scholar
• Nouvenne A, Ticinesi A, Folesani G, et al. The association of serum procalcitonin and high-sensitivity C-reactive protein with pneumonia in elderly multimorbid patients with respiratory symptoms: retrospective cohort study. BMC Geriatr. 2016;16(1):16.
   PubMedGoogle Scholar
• Dahaba AA, Rehak PH, List WF. Procalcitonin and C-reactive protein plasma concentrations in nonseptic uremic patients undergoing hemodialysis. Intensive Care Med. 2003;29(4):579–583.
   PubMed Web of Science ®Google Scholar
• Herget-Rosenthal S, Klein T, Marggraf G, et al. Modulation and source of procalcitonin in reduced renal function and renal replacement therapy. Scand J Immunol. 2005;61(2):180–186.
   PubMed Web of Science ®Google Scholar
• Stuveling EM, Hillege HL, Bakker SJL, et al. C-reactive protein is associated with renal function abnormalities in a non-diabetic population. Kidney Int. 2003;63(2):654–661.
   PubMed Web of Science ®Google Scholar
• Stevens LA, Viswanathan G, Weiner DE. Chronic kidney disease and end-stage renal disease in the elderly population: current prevalence, future projections, and clinical significance. Adv Chronic Kidney Dis. 2010;17(4):293–301.
   PubMed Web of Science ®Google Scholar
• Shamliyan T, Talley KM, Ramakrishnan R, et al. Association of frailty with survival: a systematic literature review. Ageing Res Rsvo. 2013;12(2):719–736.
   PubMed Web of Science ®Google Scholar