miR-122 regulates the JAK-STAT signalling pathway by down-regulating EPO in the mammary gland during Streptococcus agalactiae-induced mastitis

References

• Akerstedt M, Wredle E, Lam V, Johansson M. 2012. Protein degradation in bovine milk caused by Streptococcus agalactiae. J Dairy Res. 79(3):297–303.
   PubMed Web of Science ®Google Scholar
• Bartel DP. 2009. MicroRNAs: target recognition and regulatory functions. Cell. 136(2):215–233.
   PubMed Web of Science ®Google Scholar
• Boutet P, Boulanger D, Gillet L, Vanderplasschen A, Closset R, Bureau F, Lekeux P. 2004. Delayed neutrophil apoptosis in bovine subclinical mastitis. J Dairy Sci. 87(12):4104–4114.
   PubMed Web of Science ®Google Scholar
• Campo Verde Arbocco F, Persia FA, Hapon MB, Jahn GA. 2017. Hypothyroidism decreases JAK/STAT signaling pathway in lactating rat mammary gland. Mol Cell Endocrinol. 450:14–23.
   PubMed Web of Science ®Google Scholar
• Dilda F, Gioia G, Pisani L, Restelli L, Lecchi C, Albonico F, Bronzo V, Mortarino M, Ceciliani F. 2012. Escherichia coli lipopolysaccharides and Staphylococcus aureus enterotoxin B differentially modulate inflammatory microRNAs in bovine monocytes. Vet J. 192(3):514–516.
   PubMed Web of Science ®Google Scholar
• Keefe GP. 1997. Streptococcus agalactiae mastitis: a review. Can Vet J. 38(7):429–437.
   PubMed Web of Science ®Google Scholar
• Kong D, Wang Y. 2018. Knockdown of lncRNA HULC inhibits proliferation, migration, invasion, and promotes apoptosis by sponging miR-122 in osteosarcoma. J Cell Biochem. 119(1):1050–1061.
   PubMed Web of Science ®Google Scholar
• Li H, Zhang Y, Glass A, Zellweger T, Gehan E, Bubendorf L, Gelmann EP, Nevalainen MT. 2005. Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence. Clin Cancer Res. 11(16):5863–5868.
   PubMed Web of Science ®Google Scholar
• Li J, Yin P, Gong P, Lv A, Zhang Z, Liu F. 2019. 8-Methoxypsoralen protects bovine mammary epithelial cells against lipopolysaccharide-induced inflammatory injury via suppressing JAK/STAT and NF-kappaB pathway. Microbiol Immunol. 63(10):427–437.
   PubMed Web of Science ®Google Scholar
• Mollashahi B, Aghamaleki FS, Movafagh A. 2019. The roles of miRNAs in medulloblastoma: a systematic review. J Cancer Prev. 24(2):79–90.
   PubMed Web of Science ®Google Scholar
• Motaung TE, Petrovski KR, Petzer IM, Thekisoe O, Tsilo TJ. 2017. Importance of bovine mastitis in Africa. Anim Health Res Rev. 18(1):58–69.
   PubMed Web of Science ®Google Scholar
• Naeem A, Zhong K, Moisá SJ, Drackley JK, Moyes KM, Loor JJ. 2012. Bioinformatics analysis of microRNA and putative target genes in bovine mammary tissue infected with Streptococcus uberis. J Dairy Sci. 95(11):6397–6408.
   PubMed Web of Science ®Google Scholar
• Ofir R, Qing W, Krup M, Weinstein Y. 1997. Identification of genes induced by interleukin-3 and erythropoietin via the Jak-Stat5 pathway using enhanced differential display-reverse southern. J Interferon Cytokine Res. 17(5):279–286.
   PubMed Web of Science ®Google Scholar
• Pu JH, Li R, Zhang CL, Chen D, Liao XX, Zhu YH, Geng XH, Ji DJ, Mao YJ, Gong YC, et al. 2017. Expression profiles of miRNAs from bovine mammary glands in response to Streptococcus agalactiae-induced mastitis. J Dairy Res. 84(3):300–308.
   PubMed Web of Science ®Google Scholar
• Pu JH. 2017. Expression profiles of genes and microRNAs from bovine mammary glands in response to streptococcus agalatiae-induced mastitis and regulation of miR-122 on EPO and JAK-STAT pathway [D]. Yangzhou, China: Yangzhou University; p. 39–54.
   Google Scholar
• Pu JH, Zhu XR, Xu X, Lu XB, Mao YJ, Yang ZP. 2017. Culture of dairy cow primary mammary epithelial cells and expression of β-casein mRNA. Chin Anim Husband Vet Med. 44(7):1975–1981.
   Google Scholar
• Quintas-Cardama A, Verstovsek S. 2013. Molecular pathways: jak/STAT pathway: mutations, inhibitors, and resistance. Clin Cancer Res. 19(8):1933–1940.
   PubMed Web of Science ®Google Scholar
• Reichenstein M, Rauner G, Barash I. 2011. Conditional repression of STAT5 expression during lactation reveals its exclusive roles in mammary gland morphology, milk-protein gene expression, and neonate growth. Mol Reprod Dev. 78(8):585–596.
   PubMed Web of Science ®Google Scholar
• Reshi AA, Husain I, Bhat SA, Rehman MU, Razak R, Bilal S, Mir MR. 2015. Bovine mastitis as an evolving disease and its impact on the dariy industry. Int J Cur Res Rev. 7(5):48–55.
   Google Scholar
• Rinaldi M, Li RW, Capuco AV. 2010. Mastitis associated transcriptomic disruptions in cattle. Vet Immunol Immunopathol. 138(4):267–279.
   PubMed Web of Science ®Google Scholar
• Rivkin M, Simerzin A, Zorde-Khvalevsky E, Chai C, Yuval JB, Rosenberg N, Harari-Steinfeld R, Schneider R, Amir G, Condiotti R, et al. 2016. Inflammation-induced expression and secretion of microRNA 122 leads to reduced blood levels of kidney-derived erythropoietin and anemia. Gastroenterology. 151(5):999–1010 e1013.
   PubMed Web of Science ®Google Scholar
• Ruegg PL. 2017. A 100-year review: mastitis detection, management, and prevention. J Dairy Sci. 100(12):10381–10397.
   PubMed Web of Science ®Google Scholar
• Stabile H, Scarno G, Fionda C, Gismondi A, Santoni A, Gadina M, Sciume G. 2018. JAK/STAT signaling in regulation of innate lymphoid cells: the gods before the guardians. Immunol Rev. 286(1):148–159.
   PubMed Web of Science ®Google Scholar
• Thompson-Crispi K, Atalla H, Miglior F, Mallard BA. 2014. Bovine mastitis: frontiers in immunogenetics. Front Immunol. 5:493.
   PubMed Web of Science ®Google Scholar
• Usman T, Yu Y, Liu C, Wang X, Zhang Q, Wang Y. 2014. Genetic effects of single nucleotide polymorphisms in JAK2 and STAT5A genes on susceptibility of Chinese Holsteins to mastitis. Mol Biol Rep. 41(12):8293–8301.
   PubMed Web of Science ®Google Scholar
• Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. 2002. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3(7):RESEARCH0034.
   PubMed Web of Science ®Google Scholar
• Verbeke J, Van Poucke M, Peelman L, De Vliegher S. 2015. Differential expression of CXCR1 and commonly used reference genes in bovine milk somatic cells following experimental intramammary challenge. BMC Genet. 16(1):402.
   Web of Science ®Google Scholar
• Villarino AV, Kanno Y, O’Shea JJ. 2017. Mechanisms and consequences of Jak-STAT signaling in the immune system. Nat Immunol. 18(4):374–384.
   PubMed Web of Science ®Google Scholar
• Watts JL. 1988. Etiological agents of bovine mastitis. Vet Microbiol. 16(1):41–66.
   PubMed Web of Science ®Google Scholar
• Xi S, Zhang Q, Gooding WE, Smithgall TE, Grandis JR. 2003. Constitutive activation of Stat5b contributes to carcinogenesis in vivo. Cancer Res. 63(20):6763–6771.
   PubMed Web of Science ®Google Scholar
• Xiong H, Su WY, Liang QC, Zhang ZG, Chen HM, Du W, Chen YX, Fang JY. 2009. Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells. Lab Invest. 89(6):717–725.
   PubMed Web of Science ®Google Scholar
• Yao S, Yao Y, Hongyun LI, Dong N, Yan YU. 2002. Effect of inhibiting janus kinase/signal transducer and activator of transcription pathway on acute liver injury in rats with postburn Staphylococcus aureus sepsis. Chin Critic Care Med. 14(6):336–339.
   Google Scholar
• Yao XP, Cao SZ, Yang DY, Liu ZP. 2010. Molecular regulation of bovine polymorphonuclear neutrophil leukocytes (PMN) apoptosis and immunity of mammary gland. Chin Anim Husband Vet Med. 37(1):120–122.
   Google Scholar
• Yuan ZR. 2011. Study on experimental mastitis induced by Staphylococcus aureus in dairy cattle [D]. Beijing, China: Chinese Academy of Agricultural Science.
   Google Scholar
• Zhao J, Chen ZL, Wang Z, Zhang Z, Xiao Q, Guan YY, Sun H, Liu GL, Zhang XZ, Pan YC. 2016. Study on the critical pathways of dairy cow mastitis based on microarray dataset and integration analysis. Chin Anim Husband Vet Med. 43(4):862–869.
   Google Scholar
• Zhuang G, Wu X, Jiang Z, Kasman I, Yao J, Guan Y, Oeh J, Modrusan Z, Bais C, Sampath D, et al. 2012. Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J. 31(17):3513–3523.
   PubMed Web of Science ®Google Scholar