Rac GTPase regulation of 3D invasion in neuroblastomas lacking MYCN amplification

References

• Brodeur GM. Neuroblastoma: biological insights into a clinical enigma. Nature Rev Cancer 2003; 3:203-16; PMID:12612655; http://dx.doi.org/10.1038/nrc1014
   PubMed Web of Science ®Google Scholar
• Castleberry RP. Neuroblastoma. Eur J Cancer 1997; 33:1430-7; PMID:9337686; http://dx.doi.org/10.1016/S0959-8049(97)00308-0
   PubMed Web of Science ®Google Scholar
• Asgharzadeh S, Pique-Regi R, Sposto R, Wang H, Yang Y, Shimada H, Matthay K, Buckley J, Ortega A, Seeger RC. Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification. J Natl Cancer Inst 2006; 98:1193-203; PMID:16954472; http://dx.doi.org/10.1093/jnci/djj330
   PubMed Web of Science ®Google Scholar
• Ross RA, Biedler JL, Spengler BA. A role for distinct cell types in determining malignancy in human neuroblastoma cell lines and tumors. Cancer Lett 2003; 197:35-9; PMID:12880957; http://dx.doi.org/10.1016/S0304-3835(03)00079-X
   PubMed Web of Science ®Google Scholar
• Sanz-Moreno V, Marshall CJ. The plasticity of cytoskeletal dynamics underlying neoplastic cell migration. Curr Opin Cell Biol 2010; 22:690-6; PMID:20829016; http://dx.doi.org/10.1016/j.ceb.2010.08.020
   PubMed Web of Science ®Google Scholar
• Friedl P, Wolf K. Plasticity of cell migration: a multiscale tuning model. J Exp Med 2010; 207:11-9; PMID:19951899; http://dx.doi.org/10.1084/JEM2071OIA4
   PubMed Web of Science ®Google Scholar
• Sanz-Moreno V, Gadea G, Ahn J, Paterson H, Marra P, Pinner S, Sahai E, Marshall CJ. Rac activation and inactivation control plasticity of tumor cell movement. Cell 2008; 135:510-23; PMID:18984162; http://dx.doi.org/10.1016/j.cell.2008.09.043
   PubMed Web of Science ®Google Scholar
• Yamazaki D, Kurisu S, Takenawa T. Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates. Oncogene 2009; 28:1570-83; PMID:19234490; http://dx.doi.org/10.1038/onc.2009.2
   PubMed Web of Science ®Google Scholar
• Zhong J, Bach CT, Shum MS, O'Neill GM. NEDD9 Regulates 3D Migratory Activity Independent of the Rac1 Morphology Switch in Glioma and Neuroblastoma. Mol Cancer Res 2014; 12:264-73; PMID:24337070; http://dx.doi.org/10.1158/1541-7786.MCR-13-0513
   PubMed Web of Science ®Google Scholar
• Sahai E, Marshall CJ. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 2003; 5:711-9; PMID:12844144; http://dx.doi.org/10.1038/ncb1019
   PubMed Web of Science ®Google Scholar
• Spengler BA, Lazarova DL, Ross RA, Biedler JL. Cell lineage and differentiation state are primary determinants of MYCN gene expression and malignant potential in human neuroblastoma cells. Oncol Res 1997; 9:467-76; PMID:9495452
   PubMed Web of Science ®Google Scholar
• O'Neill GM. The coordination between actin filaments and adhesion in mesenchymal migration. Cell Adh Migr 2009; 3:355-7; PMID:19684475; http://dx.doi.org/10.4161/cam.3.4.9468
   PubMed Web of Science ®Google Scholar
• Theveneau E, Mayor R. Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration. Dev Biol 2012; 366:34-54; PMID:22261150; http://dx.doi.org/10.1016/j.ydbio.2011.12.041
   PubMed Web of Science ®Google Scholar
• Wiercinska E, Naber HP, Pardali E, van der Pluijm G, van Dam H, ten Dijke P. The TGF-beta/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system. Breast Cancer Res Treat 2011; 128:657-66; PMID:20821046; http://dx.doi.org/10.1007/s10549-010-1147-x
   PubMed Web of Science ®Google Scholar
• Pettee KM, Dvorak KM, Nestor-Kalinoski AL, Eisenmann KM. An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids. PloS One 2014; 9:e90371; PMID:24587343; http://dx.doi.org/10.1371/journal.pone.0090371
   PubMedGoogle Scholar
• Haeger A, Krause M, Wolf K, Friedl P. Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement. Biochim Biophys Acta 2014; 1840:2386-95; PMID:24721714; http://dx.doi.org/10.1016/j.bbagen.2014.03.020
   PubMed Web of Science ®Google Scholar
• Friedl P, Wolf K. Tube travel: the role of proteases in individual and collective cancer cell invasion. Cancer Res 2008; 68:7247-9; PMID:18794108; http://dx.doi.org/10.1158/0008-5472.CAN-08-0784
   PubMed Web of Science ®Google Scholar
• Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol 2007; 9:893-904; PMID:17618273; http://dx.doi.org/10.1038/ncb1616
   PubMed Web of Science ®Google Scholar
• Albrengues J, Meneguzzi G, Gaggioli C. Analysis of collective invasion of carcinoma cells in a 3D organotypic model. Methods Mol Biol (Clifton, NJ) 2013; 961:243-52; PMID:23325648; http://dx.doi.org/10.1007/978-1-62703-227-8_15
   PubMedGoogle Scholar
• Onesto C, Shutes A, Picard V, Schweighoffer F, Der CJ. Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. Methods Enzymol 2008; 439:111-29; PMID:18374160; http://dx.doi.org/10.1016/S0076-6879(07)00409-0
   PubMed Web of Science ®Google Scholar
• Shutes A, Onesto C, Picard V, Leblond B, Schweighoffer F, Der CJ. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. J Biol Chem 2007; 282:35666-78; PMID:17932039; http://dx.doi.org/10.1074/jbc.M703571200
   PubMed Web of Science ®Google Scholar
• Lees JG, Bach CTT, Bradbury P, Paul A, Gunning PW, O'Neill GM. The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility. Oncogene 2011; 30:1241-51; PMID:21076470; http://dx.doi.org/10.1038/onc.2010.516
   PubMed Web of Science ®Google Scholar
• Ahn J, Sanz-Moreno V, Marshall CJ. The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility. J Cell Sci 2012; 125:1814-26; PMID:22328516; http://dx.doi.org/10.1242/jcs.101444
   PubMed Web of Science ®Google Scholar
• Zhong J, Baquiran JB, Bonakdar N, Lees J, Ching YW, Pugacheva E, Fabry B, O'Neill GM. NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PloS One 2012; 7:e35058; PMID:22509381; http://dx.doi.org/10.1371/journal.pone.0035058
   PubMedGoogle Scholar
• Theveneau E, Mayor R. Can mesenchymal cells undergo collective cell migration? The case of the neural crest. Cell Adh Migr 2011; 5:490-8; PMID:22274714; http://dx.doi.org/10.4161/cam.5.6.18623
   PubMed Web of Science ®Google Scholar
• Thiele CJ. Neuroblastoma cell lines. In: Masters J (eds). Human Cell Culture 1998; vol. 1. Kluwer Academic Publishers: Lancaster, UK:21-53.
   Google Scholar
• Carey SP, Starchenko A, McGregor AL, Reinhart-King CA. Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model. Clin Exp Metastasis 2013; 30:615-30; PMID:23328900; http://dx.doi.org/10.1007/s10585-013-9565-x
   PubMed Web of Science ®Google Scholar
• Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007; 9:1392-400; PMID:18037882; http://dx.doi.org/10.1038/ncb1658
   PubMed Web of Science ®Google Scholar
• Shimada H, Chatten J, Newton WA, Jr., Sachs N, Hamoudi AB, Chiba T, Marsden HB, Misugi K. Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas. J Natl Cancer Inst 1984; 73:405-16; PMID:6589432
   PubMed Web of Science ®Google Scholar
• Cowell LN, Graham JD, Bouton AH, Clarke CL, O'Neill GM. Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway. Oncogene 2006; 25:7597-607; PMID:16799644; http://dx.doi.org/10.1038/sj.onc.1209747
   PubMed Web of Science ®Google Scholar
• Bach CT, Creed S, Zhong J, Mahmassani M, Schevzov G, Stehn J, Cowell LN, Naumanen P, Lappalainen P, Gunning PW, et al. Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol 2009; 29:1506-14; PMID:19124607; http://dx.doi.org/10.1128/MCB.00857-08
   PubMed Web of Science ®Google Scholar
• Oberthuer A, Berthold F, Warnat P, Hero B, Kahlert Y, Spitz R, Ernestus K, Konig R, Haas S, Eils R, et al. Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification. J Clinical Oncol 2006; 24:5070-8; PMID:17075126; http://dx.doi.org/10.1200/JCO.2006.06.1879
   PubMed Web of Science ®Google Scholar
• Shang X, Burlingame SM, Okcu MF, Ge N, Russell HV, Egler RA, David RD, Vasudevan SA, Yang J, Nuchtern JG. Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma. Mol Cancer Ther 2009; 8:2461-9; PMID:19671766; http://dx.doi.org/10.1158/1535-7163.MCT-08-0857
   PubMed Web of Science ®Google Scholar
• Khanna C, Jaboin JJ, Drakos E, Tsokos M, Thiele CJ. Biologically relevant orthotopic neuroblastoma xenograft models: primary adrenal tumor growth and spontaneous distant metastasis. In vivo (Athens, Greece) 2002; 16:77-85; PMID:12073775
   PubMed Web of Science ®Google Scholar
• Schwankhaus N, Gathmann C, Wicklein D, Riecken K, Schumacher U, Valentiner U. Cell adhesion molecules in metastatic neuroblastoma models. Clin Exp Metastasis 2014; 31:483-96; PMID:24549749; http://dx.doi.org/10.1007/s10585-014-9643-8
   PubMed Web of Science ®Google Scholar
• Byrne FL, Yang L, Phillips PA, Hansford LM, Fletcher JI, Ormandy CJ, McCarroll JA, Kavallaris M. RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model. Oncogene 2014; 33:882-90; PMID:23396365; http://dx.doi.org/10.1038/onc.2013.11
   PubMed Web of Science ®Google Scholar
• Yoshihara T, Esumi N, Humphries MJ, Imashuku S. Unique expression of integrin fibronectin receptors in human neuroblastoma cell lines. Int J Cancer 1992; 51:620-6; PMID:1534785; http://dx.doi.org/10.1002/ijc.2910510419
   PubMed Web of Science ®Google Scholar
• Shusterman S, Grupp SA, Barr R, Carpentieri D, Zhao H, Maris JM. The angiogenesis inhibitor tnp-470 effectively inhibits human neuroblastoma xenograft growth, especially in the setting of subclinical disease. Clin Cancer Res 2001; 7:977-84; PMID:11309349
   PubMed Web of Science ®Google Scholar