Mixture analysis on associations between semen quality and sperm DNA integrity and occupational exposure to polycyclic aromatic hydrocarbons

References

• Huang C, Li B, Xu K, et al. Decline in semen quality among 30,636 young Chinese men from 2001 to 2015. Fertil Steril. 2017;107(1):83–88. doi:10.1016/j.fertnstert.2016.09.035.
   PubMed Web of Science ®Google Scholar
• Swan SH, Elkin EP, Fenster L. Have sperm densities declined? A reanalysis of global trend data. Environ Health Perspect. 1997;105(11):1228–1232. doi:10.1289/ehp.971051228.
   PubMed Web of Science ®Google Scholar
• Sharpe RM. Hormones and testis development and the possible adverse effects of environmental chemical. Toxicol Letters. 2001;120(1–3):221–232. doi:10.1016/S0378-4274(01)00298-3.
   PubMed Web of Science ®Google Scholar
• Cheng L, Albers P, Berney DM, et al. Testicular cancer. Nat Rev Dis Primers. 2018;4(1):29. doi:10.1038/s41572-018-0029-0.
   PubMed Web of Science ®Google Scholar
• Giannandrea F, Fargnoli S. Environmental factors affecting growth and occurrence of testicular cancer in childhood: an overview of the current epidemiological evidence. Children. 2017;4(1):1. doi:10.3390/children4010001.
   PubMedGoogle Scholar
• Richiardi L, Pettersson A, Akre O. Genetic and environmental risk factors for testicular cancer. Int J Androl. 2007;30(4):230–240. doi:10.1111/j.1365-2605.2007.00760.x.
   PubMedGoogle Scholar
• Jeng HAC, Lin WY, Chao MR, Lin WY, Pan CH. Semen quality and sperm DNA damage associa -revised - final-finalted with oxidative stress in relation to exposure to polycyclic aromatic hydrocarbons. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2018;53(14):1221–1228. doi:10.1080/10934529.2018.1528035.
   PubMed Web of Science ®Google Scholar
• Jeng HA, Pan C-H, Chao M-R, et al. Sperm quality and DNA integrity of coke oven workers exposed to polycyclic aromatic hydrocarbons. Int J Occup Med Environ Health. 2016;29(6):915–926. doi:10.13075/ijomeh.1896.00598.
   PubMed Web of Science ®Google Scholar
• Kavouras IG, Koutrakis P, Tsapakis M, et al. Source apportionment of urban particulate aliphatic and polynuclear aromatic hydrocarbons (PAHs) using multivariate methods. Environ Sci Technol. 2001;35(11):2288–2294. doi:10.1021/es001540z.
   PubMed Web of Science ®Google Scholar
• Kim KH, Jahan SA, Kabir E, Brown RJC. A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects. Environ Int. 2013;60:71–80. doi:10.1016/j.envint.2013.07.019.
   PubMed Web of Science ®Google Scholar
• Li Z, Sandau CD, Romanoff LC, et al. Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population. Environ Res. 2008;107(3):320–331. doi:10.1016/j.envres.2008.01.013.
   PubMed Web of Science ®Google Scholar
• Guengerich FP. Cytochrome P450 and chemical toxicology. Chem Res Toxicol. 2008;21(1):70–83. doi:10.1021/tx700079z.
   PubMed Web of Science ®Google Scholar
• Ewa B, Danuta M-Š. Polycyclic aromatic hydrocarbons and PAH-related DNA adducts. J Appl Genet. 2017;58(3):321–330. doi:10.1007/s13353-016-0380-3.
   PubMed Web of Science ®Google Scholar
• Yang P, Wang YX, Chen YJ, et al. Urinary polycyclic aromatic hydrocarbon metabolites and human semen Quality in China. Environ Sci Technol. 2017;51(2):95.
   Web of Science ®Google Scholar
• Zini A, Jamal W, Cowan L, Al-Hathal N. Is sperm DNA damage associated with IVF embryo quality? A systematic review. J Assist Reprod Genet. 2011;28(5):391–397. doi:10.1007/s10815-011-9544-6.
   PubMed Web of Science ®Google Scholar
• Chen L, Fang J, Jiang W, Wang J, Li D. Effects of the sperm DNA fragmentation index on the clinical and neonatal outcomes of intracytoplasmic sperm injection cycles. J Ovarian Res. 2020;13(1):52. doi:10.1186/s13048-020-00658-z.
   PubMed Web of Science ®Google Scholar
• Larsen L, Scheike T, Jensen TK, et al. Computer-assisted semen analysis parameters as preductors for fertility of men from the general population. Hum Reprod. 2000;15(7):1562–1567. doi:10.1093/humrep/15.7.1562.
   PubMed Web of Science ®Google Scholar
• Keith LH. The source of U.S. EPA's Sixteen PAH priority pollutants. Polycycl Aromat Compd. 2015;35(2–4):147–160. doi:10.1080/10406638.2014.892886.
   Web of Science ®Google Scholar
• World Health Organization. WHO Laboratory Manual for the Examination and Processing of Human Semen. 5th ed. Boston: Cambridge University, PressCambridge; 2010.
   Google Scholar
• Ribeiro S, Sharma R, Gupta S, Cakar Z, De Geyter C, Agarwal A. Inter- and intra-laboratory standardization of TUNEL assay for assessment of sperm DNA fragmentation. Andrology. 2017;5(3):477–485. doi:10.1111/andr.12334.
   PubMed Web of Science ®Google Scholar
• Gedik CM, Collins A, ESCODD (European Standards Committee on Oxidative DNA Damage). Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study. Faseb J. 2005;19(1):82–84. doi:10.1096/fj.04-1767fje.
   PubMed Web of Science ®Google Scholar
• Gibson EA, Nunez Y, Abuawad A, et al. An overview of methods to address distinct research questions on environmental mixtures: an application to persistent organic pollutants and leukocyte telomere length. Environ Health. 2019;18(1):76.doi:10.1186/s12940-019-0515-1.
   PubMed Web of Science ®Google Scholar
• Liu SH, Bobb JF, Lee KH, et al. Lagged kernel machine regression for identifying time windows of susceptibility to exposures of complex mixtures. Biostatistics. 2018;19(3):325–341. doi:10.1093/biostatistics/kxx036.
   PubMed Web of Science ®Google Scholar
• Randerath K, Zhou G-D, Randerath E, Safe SH, Donnelly KC. Comparative 32P-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals. Environ Mol Mutagen. 1997;29(4):372–378. doi:10.1002/(SICI)1098-2280(1997)29:4<372::AID-EM5>3.0.CO;2-C.
   PubMed Web of Science ®Google Scholar
• Phillips DH, Arlt VM. The 32P-postlabeling assay for DNA adducts. Nat Protoc. 2007;2(11):2772–2781. doi:10.1038/nprot.2007.394.
   PubMed Web of Science ®Google Scholar
• Zhou GD, Hernandez NS, Randerath E, Randerath K. Acute elevation by short-term dietary restriction or food deprivation of type I I-compound levels in rat liver DNA. Nutr Cancer. 1999;35(1):87–95. doi:10.1207/S1532791487-95.
   PubMed Web of Science ®Google Scholar
• Bobb JF, Valeri L, Claus Henn B, et al. Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics. 2015;16(3):493–508. doi:10.1093/biostatistics/kxu058.
   PubMed Web of Science ®Google Scholar
• Bobb JF, Claus Henn B, Valeri L, Coull BA. Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression. Environ Health. 2018;17(1):67. doi:10.1186/s12940-018-0413-y.
   PubMedGoogle Scholar
• Curi SM1, Ariagno JI, Chenlo PH, et al. Asthenozoospermia: analysis of a large population. Arch Androl. 2003;49(5):343–349. doi:10.1080/01485010390219656.
   PubMed Web of Science ®Google Scholar
• Keir JLA, Cakmak S, Blais JM, White PAJ. The influence of demographic and lifestyle factors on urinary levels of PAH metabolites-empirical analyses of Cycle 2 (2009-2011) CHMS data. J Expo Sci Environ Epidemiol. 2021;31(2):386–397. doi:10.1038/s41370-020-0208-4.
   PubMed Web of Science ®Google Scholar
• Miller RL, Garfinkel R, Horton M, et al. Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohort. Chest. 2004;126(4):1071–1078., doi:10.1378/chest.126.4.1071.
   PubMed Web of Science ®Google Scholar
• Muñoz B, Albores BA. DNA damage caused by polycyclic aromatic hydrocarbons: mechanisms and markers. In: Chen C, ed. Selected Topics in DNA Repair. Rijeka, Croatia: InTech; 2011:125–144.
   Google Scholar
• Lakshman MK, Kole PL, Chaturvedi S, et al. Methyl group-induced helicity in 1,4-dimethylbenzo[c]phenanthrene and its metabolites: synthesis, physical, and biological properties. J Am Chem Soc. 2000;122(51):12629–12636. doi:10.1021/ja002072w.
   Web of Science ®Google Scholar
• Jeng HA, Pan CH, Lin WY, Wu MT, Taylor S, Chang-Chien GP, Zhou G, Diawara N. Biomonitoring of polycyclic aromatic hydrocarbons from coke oven emissions and reproductive toxicity in nonsmoking workers. J Hazard Mater 2013;244–245:436–443. doi: 10.1016/j.jhazmat.2012.11.008.
   Google Scholar
• Recio-Vega R, Olivas-Calderon E, Michel-Ramirez G, et al. Associations between sperm quality, DNA damage, and CYP1A1, GSTT1 and GSTM1 polymorphisms with 1-hydroxypyrene urinary levels in men occupationally exposed to polycyclic aromatic hydrocarbons. Int Arch Occup Environ Health. 2018;91(6):725–734. doi:10.1007/s00420-018-1320-9.
   PubMed Web of Science ®Google Scholar
• Jurewicz J, Radwan M, Sobala W, et al. Association between a biomarker of exposure to polycyclic aromatic hydrocarbons and semen quality. Int J Occup Med Environ Health. 2013;26(5):790–801. doi:10.2478/s13382-013-0152-9.
   PubMed Web of Science ®Google Scholar
• Kim A, Park M, Yoon TK, et al. Maternal exposure to benzo[b]fluoranthene disturbs reproductive performance in male offspring mice. Toxicol Lett. 2011;203(1):54–61. doi:10.1016/j.toxlet.2011.03.003.
   PubMed Web of Science ®Google Scholar
• Ji G, Yan L, Wu S, et al. Bulky DNA adducts in human sperm associated with semen parameters and sperm DNA fragmentation in infertile men: a cross-sectional study. Environ Health. 2013;12(1):82. doi:10.1186/1476-069X-12-82.
   PubMedGoogle Scholar
• Han X, Zhou N, Cui Z, et al. Association between urinary polycyclic aromatic hydrocarbon metabolites and sperm DNA damage: a population study in Chongqing, China. Environ Health Perspect. 2011;119(5):652–657. doi:10.1289/ehp.1002340.
   PubMed Web of Science ®Google Scholar
• Park J-H, Gopishetty S, Szewczuk LM, Troxel AB, Harvey RG, Penning TM. Formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: involvement of reactive oxygen species and copper(II)/copper(I) redox cycling. Chem Res Toxicol. 2005;18(6):1026–1037. doi:10.1021/tx050001a.
   PubMed Web of Science ®Google Scholar
• Quinn AM, Penning TM. Comparisons of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: effect of redox state and expression levels. Chem Res Toxicol. 2008;21(5):1086–1094. doi:10.1021/tx700345v.
   PubMed Web of Science ®Google Scholar
• Staal YCM, Hebels DGAJ, van Herwijnen MHM, Gottschalk RWH, van Schooten FJ, van Delft JHM. Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation. Carcinogenesis. 2007;28(12):2632–2640. doi:10.1093/carcin/bgm182.
   PubMed Web of Science ®Google Scholar
• Barnes JL, Zubair M, John K, Poirier MC, Martin FL. Carcinogens and DNA damage. Biochem Soc Trans. 2018;46(5):1213–1224. doi:10.1042/BST20180519.
   PubMedGoogle Scholar
• Schurdak M, Randerath EK. Effects of route of administration on tissue distribution of DNA adducts in mice: comparison of 7H-Dibenzo(c,g)carbazole, Benzo(a)pyrene, and 2-acetylaminofluorene. Can Res. 1989;49:2633–2638.
   PubMed Web of Science ®Google Scholar
• Wood AW, Levin W, Lu AYH, et al. Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: evidence for bay region activation of carcinogenic polycyclic hydrocarbons. Biochem Biophys Res Commun. 1976;72(2):680–686. doi:10.1016/S0006-291X(76)80093-9.
   PubMed Web of Science ®Google Scholar
• Malaveille C, Bartsch H, Grover PL, et al. Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100. Biochem Biophys Res Commun. 1975;66(2):693–700. doi:10.1016/0006-291X(75)90565-3.
   PubMed Web of Science ®Google Scholar
• Zenzes MT, Bielecki R, Reed TE. Detection of benzo(a)pyrene diol epoxide-DNA adducts in sperm of men exposed to cigarette smoke. Fertil Steril. 1999;72(2):330–335. doi:10.1016/S0015-0282(99)00230-7.
   PubMed Web of Science ®Google Scholar
• Conti GO, Calogero AE, Giacone F, et al. B(a)P adduct levels and fertility: a cross-sectional study in a Sicilian population. Mol Med Rep. 2017;15(5):3398–3404. doi:10.3892/mmr.2017.6396.
   PubMed Web of Science ®Google Scholar
• Ramesh A, Inyang F, Lunstra DD, et al. Alteration of fertility endpoints in adult male F-344 rats by subchronic exposure to inhaled benzo(a)pyrene. Exp Toxicol Pathol. 2008;60(4–5):269–280. doi:10.1016/j.etp.2008.02.010.
   PubMed Web of Science ®Google Scholar