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Articles

Effects of Obex in Overweight and Obese Subjects With or Without Impaired Fasting Glucose: A Pilot Study

, PhD, , BSc, , MSc, , BSc, , BSc, , MD, , MD & , MD show all

References

  • Abdali D, Samson SE, Grover AK. How effective are antioxidant supplements in obesity and diabetes? Med Princ Pract. 2015;24:201–215.
  • Arranz C, Gonzalez RM, Alvarez A, Rodriguez B, Reyes A. Reference criteria for insulin secretion indicators and of the lipid parameters in a hospital mixed population. Rev Cubana Endocrinol. 2010;21:1–12.
  • Barrett ML, Udani JK. A proprietary alpha-amylase inhibitor from white bean (Phaseolus vulgaris). A review of clinical studies on weight loss and glycemic control. Nutr J. 2011;10:24, doi:10.1186/1475-2891-10-24.
  • Bethel MA, Xu W, Theodorakis MJ. Pharmacological interventions for preventing or delaying onset of type 2 diabetes mellitus. Diabetes Obes Metab. 2015;17:231–244.
  • Buckley CM, Madden J, Balanda K, Barron S, Fahy L, Harrington J, et al. Pre-diabetes in adults 45 sources and over in Ireland: the Survey of Lifestyle, Attitudes and Nutrition in Ireland 2007. Diabet Med. 2013;30:1198–1203.
  • Burgio E, Lopomo A, Migliore L. Obesity and diabetes: from genetics to epigenetics. Mol Biol Rep. 2015;42:799–818.
  • Bustillo-Solano EE, Bustillo-Madrigal EE, Pérez-Francisco Y, Pérez-Sosa R, Brito-García A, González-Iglesias A, et al. Prevalence of diabetes mellitus and impaired fasting glucose in an area of the city of Sancti Spiritus. Rev Cubana Endocrinol. 2013;24(2):107–124.
  • Cali AM, Pierpont BM, Taksali SE, Allen K, Shaw MM, Savoye M, et al. Rosiglitazone improves glucose metabolism in obese adolescents with impaired glucose tolerance: a pilot study. Obesity (Silver Spring). 2011;19:94–99.
  • Castellanos MF, Benet M, Morejón AF, Colls Y. Obesidad abdominal, parámetro antropométrico predictivo de alteraciones del metabolismo. Rev Finlay. 2011;1:9–16.
  • Chen L, Magliano DJ, Zimmet PZ. The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives. Nat Rev Endocrinol. 2011;8:228–236.
  • de Oliveira PR, da Costa CA, de Bem GF, Cordeiro VS, Santos IB, de Carvalho LC, et al. Euterpe oleracea Mart.-derived polyphenols protect mice from diet-induced obesity and fatty liver by regulating hepatic lipogenesis and cholesterol excretion. PLoS ONE. 2015;10(12):e0143721, doi:10.1371/journal.pone.0143721.
  • Díaz ME, Jiménez S, García R, Bonet M, Wong I. Overweight, obesity, central adiposity and associated chronic diseases in Cuban adults. MEDICC Review. 2009;11:23–28.
  • Dutt HC, Singh S, Avula B, Khan IA, Bedi YS. Pharmacological review of Caralluma R.Br. with special reference to appetite suppression and anti-obesity. J Med Food. 2012;15:108–119.
  • Gamboa-Gómez CI, Rocha-Guzmán NE, Gallegos-Infante JA, Moreno-Jiménez MR, Vázquez-Cabral BD, González-Laredo RF. Plants with potential use on obesity and its complications. EXCLI Journal. 2015;14:809–831, doi:10.17179/excli2015-186.
  • Gerritsen J, Smidt H, Rijkers GT, de Vos WM. Intestinal microbiota in human health and disease: the impact of probiotics. Genes Nutr. 2011;6:209–240.
  • Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects), Lu Y, Hajifathalian K, Ezzati M, Woodward M, Rimm EB, et al. Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants. Lancet. 2014;383:970–983.
  • Griggs JL, Su XQ, Mathai ML. Caralluma fimbriata supplementation improves the appetite behavior of children and adolescents with Prader-Willi Syndrome. N Am J Med Sci. 2015;7:509–516.
  • Grover GJ, Koetzner L, Wicks J, Gahler RJ, Lyon MR, Reimer RA, et al. Effects of the soluble fiber complex PolyGlycopleX® on glucose homeostasis and body weight in young Zucker diabetic rats. Front Pharmacol. 2011;2:47, doi:10.3389/fphar.2011.00047.
  • Grube B, Chong WF, Chong PW, Riede L. Weight reduction and maintenance with IQP-PV-101: a 12-week randomized controlled study with a 24-week open label period. Obesity (Silver Spring). 2014;22:645–651.
  • Grunberger G, Jen KL, Catherine D, Artiss JD. The benefits of early intervention in obese diabetic patients with FBCX. Diabetes Metab Res Rev. 2006;23:56–62.
  • Haffner SM, Gonzalez C, Meittinen H, Kennedy E, Dtern M. A prospective analysis of the HOMA model. Diabetes Care. 1996;19:138–141.
  • Hurt RT, Ebbert JO, Schroeder DR, Croghan IT, Bauer BA, McClave SA, et al. L-Arginine for the treatment of centrally obese subjects: a pilot study. J Diet Suppl. 2014;11:40–52.
  • Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Obesity Society. Circulation. 2014;129(25 Suppl 2):S102–S138.
  • Jeon WS, Park CY. Antiobesity pharmacotherapy for patients with type 2 diabetes: focus on long-term management. Endocrinol Metab (Seoul). 2014;29:410–417.
  • Jeyaraj S, Shetty AS, Kumar CR, Nanditha A, Krishnamoorthy S, Raghavan A, et al. Liraglutide-induced acute pancreatitis. J Assoc Physicians India. 2014;62:64–66.
  • Jiménez Acosta SM, Rodríguez Suárez A, Díaz Sánchez ME. La obesidad en Cuba. Una mirada a su evolución en diferentes grupos poblacionales. RCAN Rev Cubana Aliment Nutr. 2013;23:297–308.
  • Kamel EG, McNeill G, Van Wijk MC. Usefulness of anthropometry and DXA in predicting intra-abdominal fat in obese men and women. Obes Res. 2000;8:36–42.
  • Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85:2402–2410.
  • Khavandi K, Amer H, Ibrahim B, Brownrigg J. Strategies for preventing type 2 diabetes: an update for clinicians. Ther Adv Chronic Dis. 2013;4:242–261.
  • Kim SH, Abbasi F, Lamendola C, Liu A, Schaaf P, Grove K, et al. Benefits of liraglutide treatment in overweight and obese older individuals with prediabetes. Diabetes Care. 2013;36(10):3276–3282.
  • Kurivan R, Raj T, Srinivas SK, Vaz M, Rajendran R, Kurpad AV. Effect of Caralluma fimbriata extract on appetite, food intake and anthropometry in adult Indian men and women. Appetite. 2007;48:338–344.
  • Lewis CE, McTigue KM, Burke LE, Poirier P, Eckel RH, Howard BV, et al. Mortality, health outcomes, and body mass index in the overweight range: a science advisory from the American Heart Association. Circulation. 2009;119:3263–3271.
  • Liber A, Szajewska H. Effects of inulin-type fructans on appetite, energy intake, and body weight in children and adults: systematic review of randomized controlled trials. Ann Nutr Metab. 2013;63:42–54.
  • Matthews DR, Hosker JP, Rudenki AS, Nailor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentration in man. Diabetologia. 1985;28:412–419.
  • Medialdea L, Bodas I, Carmenate MM, Del Valle A, Marrodán MD, Prado C. Effectiveness of dietary supplementation with Caralluma fimbriata in metabolic syndrome reduction during climacteric period. Nutr Clín Diet Hosp. 2015;35:56–62.
  • Monti LD, Setola E, Lucotti PC, Marrocco-Trischitta MM, Comola M, Galluccio E, et al. Effect of a long-term oral L-arginine supplementation on glucose metabolism: a randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab. 2012;14:893–900.
  • Moutzouri E, Tsimihodimos V, Rizos E, Elisaf M. Prediabetes: to treat or not to treat? Eur J Pharmacol. 2011;672(1–3):9–19, doi:10.1016/j.ejphar.2011.10.007.
  • Myers SA, Nield A, Myers M. Zinc transporters, mechanisms of action and therapeutic utility: implications for type 2 diabetes mellitus. J Nutr Metab. 2012;2012:173712, doi:10.1155/2012/173712.
  • Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–781.
  • Lorcaserin. In obesity: unacceptable risks. Prescrire Int. 2014;23:117–120.
  • Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311:806–814.
  • Parnell JA, Reimer RA. Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am J Clin Nutr. 2009;89:1751–1759.
  • Paul C, Laganà AS, Maniglio P, Triolo O, Brady DM. Inositol's and other nutraceuticals' synergistic actions counteract insulin resistance in polycystic ovarian syndrome and metabolic syndrome: state-of-the-art and future perspectives. Gynecol Endocrinol. 2016;32:431–438, doi:10.3109/09513590.2016.1144741.
  • Poddar K, Kolge S, Bezman L, Mullin GE, Cheskin LJ. Nutraceutical supplements for weight loss: a systematic review. Nutr Clin Pract. 2011;26(5):539–552.
  • Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, et al. American Heart Association; Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association scientific statement on obesity and heart disease from the obesity committee of the council on nutrition, physical activity, and metabolism. Circulation. 2006;113:898–918.
  • Portero McLellan KC, Wyne K, Villagomez ET, Hsueh WA. Therapeutic interventions to reduce the risk of progression from prediabetes to type 2 diabetes mellitus. Ther Clin Risk Manag. 2014;10:173–188.
  • Prospective Studies Collaboration, Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009;373:1083–1096.
  • Ranasinghe P, Jayawardena R, Pigera A, Katulanda P, Constantine GR, Galappaththy P. Zinc supplementation in pre-diabetes: study protocol for a randomized controlled trial. Trials. 2013;14:52, doi:10.1186/1745-6215-14-52.
  • Raynaud E, Perez-Martin A, Brun JF, Benhaddad AA, Mercier J. Revised concept for the estimation of insulin sensitivity from a single sample. Diabetes Care. 1999;22:1003–1004.
  • Reis JP, Macera CA, Araneta MR, Lindsay SP, Marshall SJ, Wingard DL. Comparison of overall obesity and body fat distribution in predicting risk of mortality. Obesity (Silver Spring). 2009;17:1232–1239.
  • Ringseis R, Keller J, Eder K. Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency. Eur J Nutr. 2012;51:1–18.
  • Samimi M, Jamilian M, Afshar Ebrahimi F, Rahimi M, Tajbakhsh B, Asemi Z. Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Clin Endocrinol (Oxf). 2015, doi:10.1111/cen.13003.
  • Scheen AJ, Van Gaal LF. Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes. Lancet Diabetes Endocrinol. 2014;2:911–922.
  • Serra-Majem L, Bautista-Castaño I. Etiology of obesity: two “key issues” and other emerging factors. Nutr Hosp. 2013;(Suppl 5):32–43.
  • Speakman JR, O'Rahilly S. Fat: an evolving issue. Dis Model Mech. 2012;5:569–573.
  • Stevens VJ, Obarzanek E, Cook NR, Lee IM, Appel LJ, Smith West D, et al. Long-term weight loss and changes in blood pressure: results of the trials of hypertension prevention, phase II. Ann Intern Med. 2001;134(1):1–11.
  • Trout KK, Homko C, Tkacs NC. Methods of measuring insulin sensitivity. Biol Res Nurs. 2007;8:305–318.
  • Tuomilehto J, Schwarz P, Lindstrom J. Long-term benefits from lifestyle interventions for type 2 diabetes prevention: time to expand the efforts. Diabetes Care. 2011;34:S210–S214.
  • Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of Açai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J. 2011;10:45, doi:10.1186/1475-2891-10-45.
  • Villanueva-Sosa LG, Cordero-Franco HF, Salinas-Martínez AM. Prevalence of prediabetes based on fasting plasma glucose and glycosylated hemoglobin in an at-risk Mexican population. Metab Syndr Relat Disord. 2015;13(8):352–355.
  • Warkentin LM, Majumdar SR, Johnson JA, Agborsangaya CB, Rueda-Clausen CF, Sharma AM, et al. Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-source prospective cohort study. BMC Med (Online). 2014;12:175, doi:10.1186/s12916-014-0175-5.
  • Weickert MO, Pfeiffer AF. Metabolic effects of dietary fiber consumption and prevention of diabetes. J Nutr. 2008;138:439–442.
  • Würtz P, Wang Q, Kangas AJ, Richmond RC, Skarp J, Tianen M, et al. Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change. PLoS Med. 2014;11:2014, e1001765, doi:10.1371/journal.pmed.1001765, eCollection 2014.
  • Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA. 2014;311:74–86.
  • Zhang F, Tong Y, Su N, Li Y, Tang L, Huang L, et al. Weight loss effect of glucagon-like peptide-1 mimetics on obese/overweight adults without diabetes: a systematic review and meta-analysis of randomized controlled trials. J Diabetes. 2015;7:329–339.

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