Abrogation of Hepatic Damage Induced by Anticancer Drug Methotrexate by Zobo (Hibiscus sabdariffa extract) Supplementation via Targeting Oxidative Hepatotoxicity in Rats

References

• Abd-allah OM, Sharafel-din AA. 2013. The possible protective effect of ginger against intestinal damage induced by methotrexate in rats. Med J Cairo Univ. 81(1):1073–1084.
   Google Scholar
• Adeyemi DO, Ukwenya VO, Obuotor EM, Adewole SO. 2014. Anti-hepatotoxic activities of Hibiscus sabdariffa L. in animal model of streptozotocin diabetes-induced liver damage. BMC Complement Altern Med. 14:277. doi:10.1186/1472-6882-14-277. PMID: 25077880.
   PubMed Web of Science ®Google Scholar
• Aebi H. 1974. Catalase. In: Bergmeyer HU (ed) Methods of enzymatic analysis. New York, NY: Academic Press, pp. 673–677.
   Google Scholar
• Ajila CM, Rao UJ. 2008. Protection against hydrogen peroxide induced oxidative damage in rat erythrocytes by Mangifera indica L. peel extract. Food Chem Toxicol. 46:303–309. doi:10.1016/j.fct.2007.08.024. PMID: 17919803.
   PubMed Web of Science ®Google Scholar
• Akbulut S, Elbe H, Eris C, Dogan Z, Toprak G, Otan E, Erdemli E, Turkoz Y. 2014. Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats. World J Gastroenterol. 20(29):10158–10165. doi:10.3748/wjg.v20.i29.10158. PMID: 25110444.
   PubMed Web of Science ®Google Scholar
• Ali BH, Mousa HM, El-Mougy S. 2003. The effect of a water extract and anthocyanins of Hibiscus sabdariffa L. on paracetamol-induced hepatotoxicity in rats. Phytother Res. 17:56–59. doi:10.1002/ptr.1084. PMID: 12557248.
   PubMed Web of Science ®Google Scholar
• Ali BH, Wabel NA, Blunden G. 2005. Phytochemical, Pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a Review. Phytother Res. 19:369–75. doi:10.1002/ptr.1628. PMID: 16106391.
   PubMed Web of Science ®Google Scholar
• Alkreathy H, Damanhouri ZA, Ahmed N, Slevin M, Ali SS, Osman AM. 2010. Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats. Food Chem Toxicol. 48:951–956. doi:10.1016/j.fct.2010.01.005. PMID: 20060872.
   PubMed Web of Science ®Google Scholar
• Awhin EP. 2012. The effect of aqueous extract of Habiscus sabdariffa L. on the activity of alkaline phosphatase and uric acid in the Liver of Rattus novergicus. Cont J Med Res. 6:12–15.
   Google Scholar
• Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. 2012. Oxidative stress and antioxidant defense. WAO J. 5:9–19.
   Google Scholar
• Chewonarin T, Kinouchi T, Kataoka K, Arimochi H, Kuwahara T, Vinitketkumnuen U, Ohnishi Y. 1999. Effects of roselle (Hibiscus sabdariffa Linn.), a Thai medicinal plant, on the mutagenicity of various known mutagens in Salmonella typhimurium and on formation of aberrant crypt foci induced by the colon carcinogens azoxymethane and 2- amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in F344 rats. Food Chem Toxicol. 37(6):591–601. doi:10.1016/S0278-6915(99)00041-1. PMID: 10478827.
   PubMed Web of Science ®Google Scholar
• Da-Costa-Rocha I, Bonnlaender B, Sievers H, Pischel I, Heinrich M. 2014. Hibiscus sabdariffa L.–A phytochemical and pharmacological review. Food Chem. 165:424–443. doi:10.1016/j.foodchem.2014.05.002. PMID: 25038696.
   PubMed Web of Science ®Google Scholar
• De S, Sen T, Chatterjee M. 2015. Reduction of oxidative stress by an ethanolic extract of leaves of Piper betle (Paan) Linn. decreased methotrexate-induced toxicity. Mol Cell Biochem. 409(1-2):191–197. doi:10.1007/s11010-015-2524-x. PMID: 26276309.
   PubMed Web of Science ®Google Scholar
• Dalaklioglu S, Genc GE, Aksoy NH, Akcit F, Gumuslu S. 2013. Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation. Human Exp Toxicol. 32(6) 662–671. doi:10.1177/0960327112468178.
   PubMed Web of Science ®Google Scholar
• Famurewa AC, Aja PM, Maduagwuna EK, Ekeleme-Egedigwe CA, Ufebe OG, Azubuike-Osu SO. 2017b. Antioxidant and anti-inflammatory effects of virgin coconut oil supplementation abrogate acute chemotherapy oxidative nephrotoxicity induced by anticancer drug methotrexate in rats. Biomed Pharmacother. 96:905–911. doi:10.1016/j.biopha.2017.12.008.
   PubMed Web of Science ®Google Scholar
• Famurewa AC, Ufebe OG, Egedigwe CA, Nwankwo OE, Obaje GS. 2017a. Virgin coconut oil supplementation attenuates acute chemotherapy hepatotoxicity induced by anticancer drug methotrexate via inhibition of oxidative stress in rats. Biomed Pharmacother. 87:437–442. doi:10.1016/j.biopha.2016.12.123.
   PubMed Web of Science ®Google Scholar
• Frank T, Netzel G, Kammerer DR, Carle R, Kler A, Kriesl E, et al. 2012. Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects. J Sci Food Agr. 92(10):2207–2218. doi:10.1002/jsfa.5615.
   PubMed Web of Science ®Google Scholar
• Gaies E, Jebabli N, Trabelsi S, Salouage I, Charfi R, Lakhal M, Klouz A. 2012. Methotrexate side effects: review article. Drug Metab Toxicol. 3:4–8.
   Google Scholar
• Hadi NR, Mohammad BI, Swadi AA. 2011. Hepatoprotective effect of omega-3 and selenium on methotrexate induced hepatotoxicity. Asian J Pharm Biol Res. 1(4):431–440.
   Google Scholar
• Hemeida RA, Mohafez OM. 2008. Curcumin attenuates methotraxate-induced hepatic oxidative damage in rats. J Egypt Natl Canc Inst. 20(2):141–8 PMID: 20029470.
   PubMedGoogle Scholar
• Huang T, Chang C, Kao E, Lin J. 2015. Effect of Hibiscus sabdariffa extract on high fat diet-induced obesity and liver damage in hamsters. Food Nutr Res. 59:29018. doi:10.3402/fnr.v59.29018. PMID: 26475512.
   PubMed Web of Science ®Google Scholar
• Johovic N, Cevik H, Sehirli OA, Yegen BC, Sener G. 2003. Melatonin prevents methotrexate-induced hepatorenal oxidative injury in rats. J Pineal Res. 34:282–287. doi:10.1034/j.1600-079X.2003.00043.x. PMID: 12662351.
   PubMed Web of Science ®Google Scholar
• Khan SA, Priyamvada S, Farooq N, Khan S, Khan W, Yusufi ANK. 2009. Protective effect of green tea extract on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney. Pharmacol Res. 59:254–262. doi:10.1016/j.phrs.2008.12.009. PMID: 19429467.
   PubMed Web of Science ®Google Scholar
• Kuriyan R, Kumar DR, Rajendran R, Kurpad AV. 2010. An evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trial. BMC Complement Altern Med. 10:27. doi:10.1186/1472-6882-10-27. PMID: 20553629.
   PubMed Web of Science ®Google Scholar
• Lin TL, Lin HH, Chen CC, Lin MC, Chou MC, Wang CJ. 2007. Hibiscus sabdariffa extract reduces serum cholesterol in men and women. Nutr Res. 27:140–145. doi:10.1016/j.nutres.2007.01.007.
   Web of Science ®Google Scholar
• Miyazono Y, Gao F, Horie T. 2004. Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats. Scand J Gastroenterol. 39:1119–1127. doi:10.1080/00365520410003605. PMID: 15545171.
   PubMed Web of Science ®Google Scholar
• Moghadam AR, Tutunchi S, Namvaran-Abbas-Abad A, Yazdi M, Bonyadi F, Mohajeri D, Mazani M, Marzban H, Łos MJ, Saeid Ghavami S. 2015. Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress. BMC Complement Altern Med. 15:246–258. doi:10.1186/s12906-015-0773-6. PMID: 26199067.
   PubMed Web of Science ®Google Scholar
• National Institutes of Health. 2008. Guide for the care and use of laboratory animals (8th ed), Washington, DC: The National Academies Press. pp. 4–8.
   Google Scholar
• Ohkawa H, Ohishi N, Yagi K. 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 95(2):351–358. doi:10.1016/0003-2697(79)90738-3. PMID: 36810.
   PubMed Web of Science ®Google Scholar
• Okoko T, Oruambo IF. 2008. The effect of Hibiscus sabdariffa calyx extract on cisplatin-induced tissue damage in rats. BIOKEMISTRI. 20(2):47–52.
   Google Scholar
• Ramos S, Alia M, Bravo L, Goya L. 2005. Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (Hep G). J Agric Food Chem. 53:1271–1280. doi:10.1021/jf0490798. PMID: 15713052.
   PubMed Web of Science ®Google Scholar
• Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG. 1973. Selenium: biochemical role as a component of glutathione peroxidase. Science. 179(4073):588–590. doi:10.1126/science.179.4073.588. PMID: 4686466.
   PubMed Web of Science ®Google Scholar
• Sail AI, Al-Mahdawi FA, Al-Lami MQ, Al-Jalabi SM. 2013. Protective effect of Vitamin A against oxidative stress caused by methotrexate. Iraqi J Sci. 54(3):585–589.
   Google Scholar
• Sharifudin SA, Fakurazi S, Hadiyat MT, Hairuszah I, Moklas MA, Arulselvan P. 2013. Therapeutic potential of Moringa oleifera extracts against acetaminophen-induced hepatotoxicity in rats. Pharm Biol. 51(3):279–288. doi:10.3109/13880209.2012.720993. PMID: 23043505.
   PubMed Web of Science ®Google Scholar
• Sun Y, Oberley LW, Li Y. 1988. A simple method for clinical assay of superoxide dismutase. Clin Chem. 34:497–500. PMID: 3349599.
   PubMed Web of Science ®Google Scholar
• Tag HM. 2015. Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate-induced hepatotoxicity in male albino rat. BMC Complement Altern Med. 15:252 doi:10.1186/s12906-015-0744-y. PMID: 26209437.
   PubMed Web of Science ®Google Scholar
• Tunali-Akbay T, Sehirli O, Ercan F, Sener G. 2010. Resveratrol protects against methotrexate-induced hepatic injury in rats. J Pharm Pharmaceut Sci. 13(2):303–310. doi:10.18433/J30K5Q.
   PubMed Web of Science ®Google Scholar
• Uzar E, Koyuncuoglu HR, Uz E, Yilmaz HR, Kutluhan S, Kilbas S, Gultekin F. 2006. The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: Protective effect of caffeic acid phenethyl ester. Mol Cell Biochem. 291:63–68. doi:10.1007/s11010-006-9196-5. PMID: 16718360.
   PubMed Web of Science ®Google Scholar
• Vardi N, Parlakpinar H, Cetin A, Erdogan A, Ozturk IC. 2010. Protective effect of beta-carotene on methotrexate-induced oxidative liver damage. Toxicol Pathol. 38(4):592–597. doi:10.1177/0192623310367806. PMID: 20448084.
   PubMed Web of Science ®Google Scholar
• Vardi N, Parlakpinar H, Ozturk F, Ates B, Gul M, Cetin A, Erdogan A, Otlu A. 2008. Potent protective effect of apricot and β-carotene on methotrexate-induced intestinal oxidative damage in rats. Food Chem Toxicol. 46:3015–3022. doi:10.1016/j.fct.2008.05.039. PMID: 18601970.
   PubMed Web of Science ®Google Scholar
• West SG. 1997. Methotrexate hepatotoxicity. Rheum Dis Clin North Am. 23:883–915. doi:10.1016/S0889-857X(05)70365-3. PMID: 9361160.
   PubMed Web of Science ®Google Scholar
• Yuksel Y, Yuksel R, Yagmurca M, Haltas H, Erdamar H, Toktas M, Ozcan O. 2017. Effects of quercetin on methotrexate-induced nephrotoxicity in rats. Human Exp Toxicol. 36(1):51–61. doi:10.1177/0960327116637414.
   PubMed Web of Science ®Google Scholar