Analysis and risk assessment of 4(5)-methylimidazole in brown colored foods and beverages

References

• AOAC International. 2002. AOAC guidelines for single laboratory validation of chemical methods for dietary supplements and botanicals. Gaithersburg, MD; [ cited 2014 Sep 22]. Available from: http://www.aoac.org/dietsupp6/Dietary-Supplement-web-site/slv_guidelines.pdf.
   Google Scholar
• Casal S, Fernandes J, Oliveira M, Ferreira M. 2002. Gas chromatographic–mass spectrometric quantification of 4-(5)-methylimidazole in roasted coffee after ion-pair extraction. J Chromatogr A. 976:285–291.
   PubMed Web of Science ®Google Scholar
• Chan P, Hills G, Kissling G, Nyska A. 2008. Toxicity and carcinogenicity studies of 4-methylimidazole in F344/N rats and B6C3F1 mice. Arch Toxicol. 82:45–53.
   PubMed Web of Science ®Google Scholar
• Chan P, Mahler J, Travlos G, Nyska A, Wenk M. 2006. Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice. Arch Toxicol. 80:169–180.
   PubMed Web of Science ®Google Scholar
• Codex Alimentarious Commission. 1993. Residues of veterinary drugs in foods. 2nd ed. Vol. 3. The Italy: Joint FAO/WHO Food Standards Program.
   Google Scholar
• Cunha C, Senra L, Fernandes J, Cunha S. 2013. Gas chromatography–mass spectrometry analysis of 4-methylimidazole in balsamic vinegars and processed sauces. Food Anal Method. 7:1519–1525.
   Web of Science ®Google Scholar
• Cunha S, Barrado A, Faria M, Fernandes J. 2011. Assessment of 4-(5)-methylimidazole in soft drinks and dark beer. J Food Comp Anal. 24:609–614.
   Web of Science ®Google Scholar
• EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS). 2011. Scientific opinion on the reevaluation of caramel colours (E 150a,b,c,d) as food additives. EFSA J. 9:1–9.
   Google Scholar
• Hengel M, Shibamoto T. 2013. Carcinogenic 4(5)-methylimidazole found in beverages, sauces, and caramel colors: chemical properties, analysis, and biological activities. J Agric Food Chem. 61:780–789.
   PubMed Web of Science ®Google Scholar
• IARC Monographs. 2012. 4-Methylimidazole. [ cited 2014 Feb 15]. Available from: Monographs.iarc.fr/ENG/Monographs/vol101/mono101-015.pdf.
   Google Scholar
• KHID. 2013. Korean health and nutrition survey and the report. Gwacheon, Republic of Korea: Ministry of Health and Welfare.
   Google Scholar
• Kim TR, Kim SU, Shin Y, Kim JY, Lee SM, Kim JH. 2013. Determination of 4-methylimidazole and 2-acetyl-4(5)-tetrahydroxybutylimidazole in caramel color and processed foods by LC-MS/MS. Prev Nutr Food Sci. 18:263–268.
   PubMedGoogle Scholar
• Klejdus B, Moravcová J, Lojková L, Vacek J, Kubáň V. 2006. Solid‐phase extraction of 4(5)‐methylimidazole (4MeI) and 2‐acetyl‐4(5)‐(1,2, 3, 4‐tetrahydroxybutyl)‐imidazole (THI) from foods and beverages with subsequent liquid chromatographic‐electrospray mass spectrometric quantification. J Separat Sci. 29:378–384.
   PubMed Web of Science ®Google Scholar
• Lachenmeier DW, Przybylski MC, Rehm J. 2012. Comparative risk assessment of carcinogens in alcoholic beverages using the margin of exposure approach. Int J Cancer. 131:E995–E1003.
   PubMed Web of Science ®Google Scholar
• Lee D, Lee KG. 2015. Analysis of aflatoxin M 1 and M 2 in commercial dairy products using high-performance liquid chromatography with a fluorescence detector. Food Control. 50:467–471.
   Web of Science ®Google Scholar
• Lee KG. 2013. Analysis and risk assessment of ethyl carbamate in various fermented foods. Eur Food Res Technol. 236:891–898.
   Web of Science ®Google Scholar
• Lee KG, Jang H, Shibamoto T. 2013. Formation of carcinogenic 4(5)-methylimidazole in caramel model systems: A role of sulphite. Food Chem. 136:1165–1168.
   PubMed Web of Science ®Google Scholar
• Li A, Wei P, Hsu HC, Cooks RG. 2013. Direct analysis of 4-methylimidazole in foods using paper spray mass spectrometry. Analyst. 138:4624–4630.
   PubMed Web of Science ®Google Scholar
• Lojková L, Klejdus B, Moravcová J, Kubáň V. 2006. Supercritical fluid extraction (SFE) of 4(5)-methylimidazole (4-MeI) and 2-acetyl-4(5)-(1,2, 3, 4)-tetrahydroxybutyl-imidazole (THI) from ground-coffee with high-performance liquid chromatographic-electrospray mass spectrometric quantification (HPLC/ESI-MS). Food Addit Contam. 23:963–973.
   PubMed Web of Science ®Google Scholar
• Moon JK, Shibamoto T. 2010. Formation of carcinogenic 4(5)-methylimidazole in Maillard reaction systems. J Agric Food Chem. 59:615–618.
   PubMed Web of Science ®Google Scholar
• Moretton C, Crétier G, Nigay H, Rocca JL. 2011. Quantification of 4-methylimidazole in class III and IV caramel colors: validation of a new method based on heart-cutting two-dimensional liquid chromatography (LC-LC). J Agric Food Chem. 59:3544–3550.
   PubMed Web of Science ®Google Scholar
• [NTP] National Toxicology Program. 2007. Toxicology and carcinogenesis of 4-methylimidazole (CAS No. 822-36-6) in F344/N rats ad B6C3F1Mice (fee studies). NTP Technical Report Series, No.535, NIH Publication No. 07-4471. Research Triangle Park, NC: U.S. Department of Health and Human Service, NTP. 1–274.
   Google Scholar
• Nationmaster. 2002. Soft drink consumption countries compared. [ cited 2015 Jun 18]. Available from: http://www.nationmaster.com/country-info/stats/Lifestyle/Food-and-drink/Soft-drink/Consumption.
   Google Scholar
• Sengar G, Sharma HK. 2014. Food caramels: a review. J Food Sci Technol. 51:1686–1696.
   PubMed Web of Science ®Google Scholar
• Seo S, Ka MH, Lee KG. 2014. Reduction of carcinogenic 4(5)-methylimidazole in a caramel model system: influence of food additives. J Agric Food Chem. 62:6481–6486.
   PubMed Web of Science ®Google Scholar
• Thomsen V, Schatzlein D, Mercuro D. 2003. Limits of detection in spectroscopy. Spectroscopy. 18:112–114.
   Web of Science ®Google Scholar
• Wang L, Ren B, Liu Y, Lu Y, Chang F, Yang L. 2015. 2-acetyl-4-tetrahydroxybutylimidazole and 4-methylimidazole in caramel colours, vinegar and beverages in China. Food Addit Contam B. 8:163–168.
   Google Scholar
• Wu XL, Yu SJ, Kang KR. 2015. Development of a monoclonal antibody-based indirect competitive immunosorbent assay for 4(5)-methylimidazole detection in caramels. Food Chem. 170:354–359.
   PubMed Web of Science ®Google Scholar
• Yamaguchi H, Masuda T. 2011. Determination of 4(5)-methylimidazole in soy sauce and other foods by LC-MS/MS after solid-phase extraction. J Agric Food Chem. 59:9770–9775.
   PubMed Web of Science ®Google Scholar