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Original

Cause-Specific Treatment in Patients with High Sperm DNA Damage Resulted in Significant DNA Improvement

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Pages 109-115 | Received 30 Sep 2008, Accepted 04 Jan 2009, Published online: 13 Aug 2009

References

  • Agarwal A., Nallella K. P., Allamaneni S. S., Said T. M. Role of antioxidants in treatment of male infertility: An overview of the literature. Reprod Biomed Online 2004; 8: 616–627
  • Agarwal A., Said T. M. Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 2003; 9: 331–345
  • Aitken R. J., Gordon E., Harkiss D., Twigg J. P., Milne P., Jennings Z., Irvine D. S. Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa. Biol Reprod 1998; 59: 1037–1046
  • Benchaib M., Lornage J., Mazoyer C., Lejeune H., Salle B., Guerin J. F. Sperm deoxyribonucleic acid fragmentation as a prognostic indicator of assisted reproductive technology outcome. Fertil Steril 2007; 87: 93–100
  • Bungum M., Humaidan P., Axmon A., Spano M., Bungum L., Erenpreiss J., Giwercman A. Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome. Hum Reprod 2007; 22: 174–179
  • Carrell D. T., Liu L., Peterson C. M., Jones K. P., Hatasaka H., Erickson L., Campbell B. Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss. Arch Androl 2003; 49: 49–55
  • Erenpreiss J., Hlevicka S., Zalkalns J., Erenpreisa J. Effect of leukocytospermia on sperm DNA integrity: A negative effect in abnormal semen samples. J Androl 2002; 23: 717–723
  • Eskenazi B., Kidd S. A., Marks A. R., Sloter E., Block G., Wyrobek A. J. Antioxidant intake is associated with semen quality in healthy men. Hum Reprod 2005; 20: 1006–1012
  • Evenson D. P., Larson K. L., Jost L. K. Sperm chromatin structure assay: Its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 2002; 23: 25–43
  • Gallegos G., Ramos B., Santiso R., Goyanes V., Gosalvez J., Fernandez J. L. Sperm DNA fragmentation in infertile men with genitourinary infection by Chlamydia trachomatis and Mycoplasma. Fertil Steril 2008; 90: 328–334
  • Gandini L., Lombardo F., Paoli D., Caponecchia L., Familiar G., Verlengia C., Dondero F., Lenzi A. Study of apoptotic DNA fragmentation in human spermatozoa. Hum Reprod 2000; 15: 830–839
  • Goldstein M., Gilbert B. R., Dicker A. P., Dwosh J., Gnecco C. Microsurgical inguinal varicocelectomy with delivery of the testis: An artery and lymphatic sparing technique. J Urol 1992; 148: 1808–1811
  • Greco E., Iacobelli M., Rienzi L., Ubaldi F., Ferrero S., Tesarik J. Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment. J Androl 2005; 26: 349–353
  • Keck C., Gerber-Schäfer C., Clad A., Wilhelm C., Breckwoldt M. Seminal tract infections: impact on male fertility and treatment options. Hum Reprod Update 1998; 4: 891–903
  • Keskes-Ammar L., Feki-Chakroun N., Rebai T., Sahnoun Z., Ghozzi H., Hammami S., Zghal K., Fki H., Damak J., Bahloul A. Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men. Arch Androl 2003; 49: 83–94
  • Martin R. H., Rademaker A. W. The effect of age on the frequency of sperm chromosomal abnormalities in normal men. Am J Hum Genet 1987; 41: 484–492
  • Menezo Y. J., Hazout A., Panteix G., Robert F., Rollet J., Cohen-Bacrie P., Chapuis F., Clement P., Benkhalifa M. Antioxidants to reduce sperm DNA fragmentation: An unexpected adverse effect. Reprod Biomed Online 2007; 14: 418–421
  • Moskovtsev S. I., Willis J., Azad A., Mullen J. B. M. Sperm DNA integrity: Correlation with sperm plasma membrane integrity in semen evaluated for male infertility. Arch Androl 2005; 51: 33–40
  • Moskovtsev S. I., Willis J., Mullen J. B. M. Age-related decline in sperm deoxyribonucleic acid integrity in patients evaluated for male infertility. Fertil Steril 2006; 85: 496–499
  • Moskovtsev S. I., Willis J., White J., Mullen J. B. M. Leukocytospermia: Relationship to sperm deoxyribonucleic acid integrity in patients evaluated for male factor infertility. Fertil Steril 2007; 88: 737–740
  • Ochsendorf F. R. Infections in the male genital tract and reactive oxygen species. Hum Reprod Update 1999; 5: 399–420
  • Saleh R. A., Agarwal A., Sharma R. K., Said T. M., Sikka S. C., Thomas A. J. Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele. Fertil Steril 2003; 80: 1431–1436
  • Sharpe R. M., Skakkebaek N. E. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?. Lancet 1993; 341: 1392–1395
  • Sikka S. C. Role of oxidative stress and antioxidants in andrology and assisted reproductive technology. J Androl 2004; 25: 5–18
  • Silver E. W., Eskenazi B., Evenson D. P., Block G., Young S., Wyrobek A. J. Effect of antioxidant intake on sperm chromatin stability in healthy non-smoking men. J Androl 2005; 26: 550–556
  • Singh N. P., Muller C. H., Berger R. E. Effects of age on DNA double-strand breaks and apoptosis in human sperm. Fertil Steril 2003; 80: 1420–1430
  • Spano M., Bonde J. P., Hjollund H. I., Kolstad H. A., Cordelli E., Leter G. Sperm chromatin damage impairs human fertility. The Danish First Pregnancy Planner Study Team. Fertil Steril 2000; 73: 43–50
  • Tesarik J., Greco E., Mendoza C. Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation. Hum Reprod 2004a; 19: 611–615
  • Tesarik J., Ubaldi F., Rienzi L., Martinez F., Iacobelli M., Mendoza C., Greco E. Caspase-dependent and -independent DNA fragmentation in Sertoli and germ cells from men with primary testicular failure: Relationship with histological diagnosis. Hum Reprod 2004b; 19: 254–261
  • Vicari E. Effectiveness and limits of antimicrobial treatment on seminal leukocyte concentration and related reactive oxygen species production in patients with male accessory gland infection. Hum Reprod 2000; 15: 2536–2544
  • Wong W. Y., Thomas C. M., Merkus J. M., Zielhuis G. A., Steegers-Theunissen R. P. Male factor subfertility: Possible causes and the impact of nutritional factors. Fertil Steril 2000; 73: 435–442
  • World Health Organization (1999) WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed. Cambridge, UK: Cambridge University Press
  • Zini A., Blumenfeld A., Libman J., Willis J. Beneficial effect of microsurgical varicocelectomy on human sperm DNA integrity. Hum Reprod 2005; 20: 1018–1021
  • Zini A. Varicocelectomy: microsurgical subinguinal technique is the treatment of choice. Can Urol Assoc J 2007; 1: 273–276

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