154
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar

, , , , &
Pages 2108-2113 | Received 04 Jul 2013, Accepted 20 Sep 2013, Published online: 20 Nov 2013

References

  • Antignac J-P, Le Bizec B, Monteau F, Andre F. 2002. Validation of analytical methods based on mass spectrometric detection according to the “2002/657/EC” European decision: guideline and application. Anal Chim Acta. 483:325–334.
  • Braden BB, Talboom JS, Crain ID, Simard AR, Lukas RJ, Prokai L, Scheldrup MR, Bowman BL, Bimonte-Nelson HA. 2010. Medroxyprogesterone acetate impairs memory and alters the GABAergic system in aged surgically menopausal rats. Neurobiol Lear Mem. 93:444–453.
  • Chifang P, Chuanlai X, Zhengyu J, Xiaogang C, Liying W. 2006. Determination of anabolic steroid residues (medroxyprogesterone acetate) in pork by ELISA and comparison with liquid chromatography tandem mass spectrometry. J Food Sci. 71:C44–C50.
  • Clark M, Sowers M, Nichols S, Levy B. 2004. Bone mineral density changes over two years in first-time users of depot medroxyprogesterone acetate. Fertil Steril. 82:1580–1586.
  • Clark MK, Dillon JS, Sowers M, Nichols S. 2005. Weight, fat mass, and central distribution of fat increase when women use depot-medroxyprogesterone acetate for contraception. Int J Obes Relat Metab Disord. 29:1252–1258.
  • Commission of the European Communities. 2002. Commission Decision, 2002/657/EC implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results (Text with EEA relevance) (notified under document number C(2002) 3044). Off J Eur Commun. L221:8–36.
  • Commission of the European Communities. 2003. Commission Decision, 2003/181/EC amending Decision 2002/657/EC as regards the setting of minimum required performance limits (MRPLs) for certain residues in food of animal origin (Text with EEA relevance) (notified under document number C(2003) 764). Off J Eur Commun. L71:17–18.
  • Costard S, Porphyre V, Messad S, Rakotondrahanta S, Vidon H, Roger F, Pfeiffer DU. 2009. Multivariate analysis of management and biosecurity practices in smallholder pig farms in Madagascar. Prev Vet Med. 92:199–209.
  • Courtheyn D, Le Bizec B, Brambilla G, De Brabander HF, Cobbaert E, Van de Wiele M, Vercammen J, De Wasch K. 2002. Recent developments in the use and abuse of growth promoters. Anal Chim Acta. 473:71–82.
  • De Brabander HF, Le Bizec B, Pinel G, Antignac J-P, Verheyden K, Mortier V, Courtheyn D, Noppe H. 2007. Past, present and future of mass spectrometry in the analysis of residues of banned substances in meat-producing animals. J Mass Spectrom. 42:983–998.
  • De Brabander HF, Van Hoof J. 1990. HPTLC analysis of residues of anabolics in meat and kidney fat. J Planar Chromatogr. 3:236-242.
  • Hamoir T, Pottie G, Courtheyn D, De Brabander H, Delahaut P, Leyssens L. 1998. Comparison of purification procedures for the isolation and detection of anabolic residues in faeces using gas chromatography mass spectrometry. 3rd International Symposium on Hormone and Veterinary Drug Residue Analysis; 1998 Jun 2–5. Oud St Jan (Belgium): Analyst; p. 2621–2624.
  • Heaton KL, Smith GC, Sofos JN, Aaronson MJ, Jones DK. 1996. Analysis of pork products for chemical residues. J Muscle Foods. 7:213–224.
  • Impens S, Courtheyn D, De Wasch K, De Brabander HF. 2003. Faster analysis of anabolic steroids in kidney fat by downscaling the sample size and using gas chromatography-tandem mass spectrometry. 4th International Symposium on Hormone and Veterinary Drug Residue Analysis; 2002 Jun 4. Antwerp, Belgium: Anal Chim Acta. 483:N1–N4, 1–432.
  • Impens S, De Wasch K, Cornelis M, De Brabander HF. 2002. Analysis on residues of estrogens, gestagens and androgens in kidney fat and meat with gas chromatography-tandem mass spectrometry. J Chromatogr A. 970:235–247.
  • Ishida Y, Heersche JNM. 2002. Pharmacologic doses of medroxyprogesterone may cause bone loss through glucocorticoid activity: an hypothesis. Osteoporos Int. 13:601–605.
  • Le Bizec B, Pinel G, Antignac J-P. 2009. Options for veterinary drug analysis using mass spectrometry. J Chromatogr A. 1216:8016–8034.
  • Madec F, Hurnik D, Porphyre V, Cardinale E. 2010. Good practices for biosecurity in the pig sector – issues and options in developing and transition countries. Rome: FAO.
  • Malagasy Ministry of Agriculture. 2006. Malagasy regulation relative to Livestock Production in Madagascar. 2006/030, Article 67. Antananarivo: Official Bulletin.
  • Matson S, Henderson K, McGrath G. 1997. Physical findings and symptoms of depot medroxyprogesterone acetate use in adolescent females. J Pediatr Adolesc Gynecol. 10:18–23.
  • Meyer HHD. 2001. Biochemistry and physiology of anabolic hormones used for improvement of meat production. APMIS. 109:1–8.
  • Noppe H, Le Bizec B, Verheyden K, De Brabander HF. 2008. Novel analytical methods for the determination of steroid hormones in edible matrices. Anal Chim Acta. 611:1–16.
  • Office of Inspector General. 2011. Audit of USAID/Madagascar’s family planning and reproductive health activities. Pretoria: USAID.
  • Oksbjerg N, Petersen JS, Sórensen MT, Henckel P, Agergaard N, Bejerholm C, Erlandsen E. 1995. The influence of porcine growth hormone on muscle fibre characteristics, metabolic potential and meat quality. Meat Sci. 39:375–385.
  • Peng C-F, Chen Y-W, Chen W, Xu C-L, Kim J-M, Jin Z-Y. 2008. Development of a sensitive heterologous ELISA method for analysis of acetylgestagen residues in animal fat. Food Chem. 109:647–653.
  • Pfizer Canada Inc. 2011. Product monograph – DEPO-PROVERA et de DEPO-PROVERA-SC (acétate de médroxyprogestérone) [Internet]. [cited 2013 Feb 20]. Available from: http://www.pfizer.ca/fr/our_products/products/monograph/181
  • Rakotoharinome M, Andriamanivo H, Blaga R, Perret C, Lacour SA, Grasset-Chevillot A, Mace P, Thomas M, Villena I, Aubert D, et al. 2012. Toxoplasmosis and trichinellosis: an epidemiological survey of pig population in Madagascar. Cluj-Napoca: XI European Multicolloquium of Parasitology.
  • Rakotoharinome M, Randriamparany T, Pognon D, Chane Ming J, Idoumbin JP, Cardinale E, Porphyre V. 2013. Prevalence of antimicrobial residues in pork meat in Madagascar. Trop Anim Health Prod. DOI: 10.1007/s11250-013-0445-9.
  • Randriamparany T, Grenier A, Tourette I, Maharavo Rahantamalala CY, Rousset D, Lancelot R. 2005. Situation épidémiologique de la peste porcine africaine dans la région du Lac Alaotra et conséquences possibles pour l‘organisation de la lutte et de la surveillance. Rev Elev Méd Vét Pays Trop. 58:15–20.
  • Ravaomanana J, Jori F, Vial L, Pérez-Sánchez R, Blanco E, Michaud V, Roger F. 2011. Assessment of interactions between African swine fever virus, bushpigs (Potamochoerus larvatus), Ornithodoros ticks and domestic pigs in north-western Madagascar. Transboundary Emerg Dis. 58:247–254.
  • Smets F, DeBrabander HF, Pottie G. 1997. Enhancing the specificity of residue analysis for anabolics using HPLC clean up. Arch Lebensm Hyg. 48:30–34.
  • Temmam S, Besnard L, Andriamandimby SF, Foray C, Rasamoelina-Andriamanivo H, Heraud JM, Cardinale E, Dellagi K, Pavio N, Pascalis H, et al. 2013. High prevalence of hepatitis E in humans and pigs and evidence of genotype-3 virus in swine, Madagascar. Am J Trop Med Hyg. 88:329–338.
  • Tielen MJM. 2003. The Medroxy Progesteron Acetate (MPA) – case in Europe: an example of the weakest links in the Quality Assurance System of the Feed Industry to produce Wholesome Food for All International Congress in Animal Hygiene; Feb. 2003; Mexico: ISAH; p. 51–58.
  • Unusan N. 2008. Determination of clenbuterol in UHT milk in Turkey. Int J Food Sci Technol. 43:617–619.
  • van Leengoed L, Kluivers M, Herbes R, Langendijk P, Stephany R, van den Berg M, Seinen W, Grinwis G, van der Lugt J, Meulders F, et al. 2002. The weakest link: medroxyprogesterone acetate in pig feed. Tijdschr Diergeneeskd. 127:516–519.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.