Advanced search
Publication Cover
Food Additives & Contaminants: Part A Volume 31, 2014 - Issue 1
Submit an article Journal homepage
733
Views
40
CrossRef citations to date
0
Altmetric
Original Articles

Screening and determination of sibutramine in adulterated herbal slimming supplements by HPTLC-UV densitometry

Caroline MathonOfficial Food and Veterinary Control Authority of Geneva, Quai Ernest-Ansermet 22, CH-1211Geneva 4, Switzerland;School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211Geneva 4, Switzerland
,
Anita AnkliCAMAG Laboratory, Sonnenmattstrasse 11, CH-4132Muttenz, Switzerland
,
Eike ReichCAMAG Laboratory, Sonnenmattstrasse 11, CH-4132Muttenz, Switzerland
,
Stefan BieriOfficial Food and Veterinary Control Authority of Geneva, Quai Ernest-Ansermet 22, CH-1211Geneva 4, Switzerland
&
Philippe ChristenSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211Geneva 4, SwitzerlandCorrespondence[email protected]
Pages 15-20 | Received 02 Oct 2013, Accepted 30 Oct 2013, Published online: 15 Jan 2014

References

  • Ancuceanu R, Dinu M, Arama C. 2013. Weight loss food supplements: adulteration and multiple quality issues in two products of Chinese origin. Farmacia (Bucharest, Rom). 61:28–44.
  • Ariburnu E, Uludag MF, Yalcinkaya H, Yesilada E. 2012. Comparative determination of sibutramine as an adulterant in natural slimming products by HPLC and HPTLC densitometry. J Pharm Biomed Anal. 64–65:77–81.
  • Bland JM, Altman DG. 2012. Agreed statistics: Measurement method comparison. Anesthesiology. 116:182–185.
  • Bogusz MJ, Hassan H, Al-Enazi E, Ibrahim Z, Al-Tufail M. 2006. Application of LC–ESI–MS–MS for detection of synthetic adulterants in herbal remedies. J Pharm Biomed Anal. 41:554–564.
  • Chen Y, Zhao L, Lu F, Yu Y, Chai Y, Wu Y. 2009. Determination of synthetic drugs used to adulterate botanical dietary supplements using QTRAP LC-MS/MS. Food Addit Contam Part A. 26:595–603.
  • Cheng S-C, Huang M-Z, Shiea J. 2011. Thin layer chromatography/mass spectrometry. J Chromatogr A. 1218:2700–2711.
  • Cohen P, Benner C, McCormick D. 2012. Use of a pharmaceutically adulterated dietary supplement, Pai You Guo, among Brazilian-born women in the United States. J Gen Intern Med. 27:51–56.
  • Domenech-Carbo A, Martini M, Machado dCL, Viana C, Domenech-Carbo MT, Silva M. 2013. Screening of pharmacologic adulterant classes in herbal formulations using voltammetry of microparticles. J Pharm Biomed Anal. 74:194– 204.
  • European Medicines Agency. 2003. Committee for medicinal products for human use. Referral Sibutramine. CPMP/4514/02. London (UK): EMA.
  • European Medicines Agency. 2010. European Medicines Agency recommends suspension of marketing authorisations for sibutramine. Press release. EMA/39408/2010. London (UK): EMA.
  • [FDA] Food and Drug Administration. 2010. FDA drug safety communication: FDA recommends against the continued use of Meridia (sibutramine) [Internet]. 8 October 2010. [cited 2013 Nov 25]. Available from: http://www.fda.gov/Drugs/DrugSafety/ucm228746.htm
  • [FDA] Food and Drug Administration. 2011. Safety alerts for Human medical products, products with undeclared drug ingredients [Internet]. [cited 2013 Nov 25]. Available from: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm238512.htm
  • [FDA] Food and Drug Administration. 2012. Safety alerts for Human medical products, products with undeclared drug ingredients [Internet]. [cited 2013 Nov 25]. Available from: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm285497.htm
  • Kanan S, Abu-Yousef IA, Gunasekar C, Abdo N, Narasimhan S. 2009. Detection and quantification of synthetic drugs in herbal slimming formula. Eur J Sci Res. 34:348–357.
  • Kim JW, Kweon SJ, Park SK, Kim JY, Lee JH, Han KM, Cho S, Kim J, Han SY, Kim HJ, et al. 2013. Isolation and identification of a sibutramine analogue adulterated in slimming dietary supplements. Food Addit Contam: Part A. 30:1221–1229.
  • Kim SH, Lee J, Yoon T, Choi J, Choi D, Kim D, Kwon SW. 2009. Simultaneous determination of anti-diabetes/anti-obesity drugs by LC/PDA, and targeted analysis of sibutramine analog in dietary supplements by LC/MS/MS. Biomed Chromatogr. 23:1259–1265.
  • Lai K-C, Liu Y-C, Tseng M-C, Lin Y-L, Jer-Huei L. 2007. Isolation and identification of a sibutramine analogue in a healthy food for weight loss. J Food Drug Anal. 15:20–24.
  • Park S-r, Lee JG, Roh SH, Kim G, Kwon CH, Park HR, Kwon KS, Kim D, Kwon SW. 2012. Determination of PDE-5 inhibitors and appetite suppressants in adulterated dietary supplements using LC/PDA and LC/MS. Food Addit Contam Part B. 5:29–32.
  • Phattanawasin P, Sotanaphun U, Sukwattanasinit T, Akkarawaranthorn J, Kitchaiya S. 2012. Quantitative determination of sibutramine in adulterated herbal slimming formulations by TLC-image analysis method. Forensic Sci Int. 219:96–100.
  • Rebiere H, Guinot P, Civade C, Bonnet PA, Nicolas A. 2012. Detection of hazardous weight-loss substances in adulterated slimming formulations using ultra-high-pressure liquid chromatography with diode-array detection. Food Addit Contam Part A. 29:161–171.
  • Reich E, Schibli A. 2006. High-performance thin-layer chromatography for the analysis of medicinal plants. New York: Thieme Medical Publishers, INC.
  • Vaysse J, Balayssac S, Gilard V, Desoubdzanne D, Malet-Martino M, Martino R. 2010. Analysis of adulterated herbal medicines and dietary supplements marketed for weight loss by DOSY 1H-NMR. Food Addit Contam Part A. 27:903–916.
  • Wang H, Wu Y, Zhao Y, Sun W, Ding L, Guo B, Chen B. 2012. Rapid screening of illicit additives in weight loss dietary supplements with desorption corona beam ionisation (DCBI) mass spectrometry. Food Addit Contam Part A. 29:1194–1201.
  • Yuen YP, Lai CK, Poon WT, Ng SW, Chan AY, Mak TW. 2007. Adulteration of over-the-counter slimming products with pharmaceutical analogue--an emerging threat. Hong Kong Med J. 13:216–220.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.