Determination of N-nitrosamines in processed meats by liquid extraction combined with gas chromatography-methanol chemical ionisation/mass spectrometry

References

• Andrade R, Reyes FGR, Rath S. 2005. A method for the determination of volatile N-nitrosamines in food by HS-SPME-GC-TEA. Food Chem. 91:173–179.
   Web of Science ®Google Scholar
• Andrée S, Jira W, Schwind K-H, Wagner H, Schwägele F. 2010. Chemical safety of meat and meat products. Meat Sci. 86:38–48.
   PubMed Web of Science ®Google Scholar
• AOAC. 1990. N-nitrosamines (volatile) in Fried Bacon. Mineral oil vacuum distillation – thermal energy analyzer method. No 982.22. In: Official methods of analysis of AOAC international. 15th ed. Mishawaka: AOAC International.
   Google Scholar
• AOAC. 2002. AOAC guidelines for single laboratory validation of chemical methods for dietary supplements and botanicals. Arlington: AOAC International.
   Google Scholar
• Bellatti M, Parolari G. 1982. Aliphatic secondary amines in meat and fish products and their analysis by high pressure liquid chromatography. Meat Sci. 7:59–65.
   PubMed Web of Science ®Google Scholar
• Bellec G, Cauvin JM, Salaun MC, Le Calvé K, Dréano Y, Gouérou H, Ménez JF, Berthou F. 1996. Analysis of N-nitrosamines by high-performance liquid chromatography with post-column photohydrolysis and colorimetric detection. J Chromatogr A. 727:83–92.
   PubMed Web of Science ®Google Scholar
• Bryan NS, van Grinsven H. 2013. The role of nitrate in human health. Adv Agron. 119:153–182.
   Web of Science ®Google Scholar
• Bull RJ, Reckhow DA, Rotello V, Bull OM, Kim J. 2006. Use of toxicological and chemical models to prioritize DBP research. London: IWA Publishing.
   Google Scholar
• Byun MW, Ahn HJ, Kim JH, Lee JW, Yook HS, Han SB. 2004. Determination of volatile N-nitrosamines in irradiated fermented sausage by gas-chromatography coupled to a thermal energy analyzer. J Chromatogr A. 1054:403–407.
   PubMed Web of Science ®Google Scholar
• Campillo N, Viñas P, Martínez-Castillo N, Hernández-Córdoba M. 2011. Determination of volatile nitrosamines in meat products by microwave-assisted extraction and dispersive liquid-liquid microextraction coupled to gas chromatography-mass spectrometry. J Chromatogr A. 1218:1815–1821.
   PubMed Web of Science ®Google Scholar
• Cheng CF, Tsang CW. 1999. Separation of N-nitrosoamino acids by C18 reversed-phase ion-pair high-performance liquid chromatography and compatible detection by electrospray ionization mass spectrometry. J Chromatogr A. 849:389–402.
   PubMed Web of Science ®Google Scholar
• Chienthavorn O, Subprasert P, Insuan W. 2014. Nitrosamines extraction from Frankfurter sausages by using superheated water. Sep Sci Technol. 49:838–846.
   Web of Science ®Google Scholar
• Crews C. 2010. The determination of N-nitrosamines in food. Qual Assur Saf Crops Foods. 2:2–12.
   Web of Science ®Google Scholar
• Demeyer D, Honikel K, De Smet S. 2008. The World Cancer Research Fund report 2007: a challenge for the meat processing industry. Meat Sci. 80:953–959.
   Google Scholar
• EPA–U.S. Environmental Protection Agency. 1996. Method 8070A: nitrosamines by gas chromatography. Washington (DC): Environmental Protection Agency.
   Google Scholar
• Herrmann SS, Duedahl-Olesen L, Granby K. 2014. Simultaneous determination of volatile and non-volatile nitrosamines in processed meat products by liquid chromatography tandem mass spectrometry using atmospheric pressure chemical ionisation and electrospray ionisation. J Chromatogr A. 1330:20–29.
   PubMed Web of Science ®Google Scholar
• Huang M-C, Chen H-C, Fu S-C, Ding W-H. 2013. Determination of volatile N-nitrosamines in meat products by microwave-assisted extraction coupled with dispersive micro solid-phase extraction and gas chromatography – chemical ionisation mass spectrometry. Food Chem. 138:227–233.
   PubMed Web of Science ®Google Scholar
• Kocak D, Ozel MZ, Gogus F, Hamilton JF, Lewis AC. 2012. Determination of volatile nitrosamines in grilled lamb and vegetables using comprehensive gas chromatography –nitrogen chemiluminescence detection. J Agric Food Chem. 135:2215–2220.
   Web of Science ®Google Scholar
• Massey RC, Key PE, Jones RA, Logan GL. 1991. Volatile, non‐volatile and total N‐nitroso compounds in bacon. Food Addit Contam. 8:585–598.
   PubMed Web of Science ®Google Scholar
• [MSDS] Material Safety Data Sheets. 2014. [Internet; cited 2014 Aug 29]. Available from: http://www.msds.com/
   Google Scholar
• Oostindjer M, Alexander J, Amdam GV, Andersen G, Bryan NS, Chen D, Corpet DE, De Smet S, Dragsted LO, Haug A, et al. 2014. The role of red and processed meat in colorectal cancer development: a perspective. Meat Sci. 97:583–596.
   PubMed Web of Science ®Google Scholar
• Ozel MZ, Gogus F, Yagci S, Hamilton JF, Lewis AC. 2010. Determination of volatile nitrosamines in various meat products using comprehensive gas chromatography-nitrogen chemiluminescence detection. Food Chem Toxicol. 48:3268–3273.
   PubMed Web of Science ®Google Scholar
• Pegg RB, Shaidi F. 2000. Nitrite curing of meat: the N-nitrosamine problem and nitrite alternatives. Trumbull: Food and Nutrition Press.
   Google Scholar
• Püssa T. 2013. Toxicological issues associated with production and processing of meat. Meat Sci. 95:844–853.
   PubMed Web of Science ®Google Scholar
• Ramezani H, Hosseini H, Kamankesh M, Ghasemzadeh-Mohammadi V, Mohammadi A. 2014. Rapid determination of nitrosamines in sausage and salami using microwave-assisted extraction and dispersive liquid–liquid microextraction followed by gas chromatography-mass spectrometry. Eur Food Res Technol. 240:441–450.
   Web of Science ®Google Scholar
• Raoul S, Gremaud E, Biaudet H, Turesky RJ. 1997. Rapid solid-phase extraction method for the detection of volatile nitrosamines in food. J Agric Food Chem. 45:4706–4713.
   Web of Science ®Google Scholar
• Rath S, Reyes FGR. 2011. Nitrosamines. In: Nollet LML, Toldrá F, editors. Safety analysis of foods of animal origin. Boca Raton (FL): CRC Press.
   Google Scholar
• Rohrbaugh DK. 2000. Methanol chemical ionization quadrupole ion trap mass spectrometry of O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothiolate (VX) and its degradation products. J Chromatogr A. 893:393–400.
   PubMed Web of Science ®Google Scholar
• Sanches Filho PJ, Rios A, Valcárcel M, Melecchi MI, Caramão EB. 2007. Method of determination of nitrosamines in sausages by CO2 supercritical fluid extraction (SFE) and micellar electrokinetic chromatography (MEKC). J Agric Food Chem. 55:603–607.
   PubMed Web of Science ®Google Scholar
• Sannino A, Bolzoni L. 2013. GC/CI–MS/MS method for the identification and quantification of volatile N-nitrosamines in meat products. Food Chem. 141:3925–3930.
   PubMed Web of Science ®Google Scholar
• Sen NP, Seaman SW, Page BD. 1997. Rapid semi-quantitative estimation of N-nitrosodibutylamine and N-nitrosodibenzylamine in smoked hams by solid-phase microextraction followed by gas chromatography-thermal energy analysis. J Chromatogr A. 788:131–140.
   PubMed Web of Science ®Google Scholar
• Skibsted LH. 2011. Nitric oxide and quality and safety of muscle based foods. Nitric Oxide. 24:176–183.
   PubMed Web of Science ®Google Scholar
• Terra NN. 2005. Apontamentos de tecnologia de carnes. São Leopoldo: Unisinos.
   Google Scholar
• Tricker AR, Perkins MJ, Massey RC, Bishop C, Key PE, Mcweeny DJ. 1984. Incidence of some non‐volatile N‐nitroso compounds in cured meats. Food Addit Contam. 1:245–252.
   PubMedGoogle Scholar
• Tricker AR, Preussmann R. 1991. Carcinogenic N-nitrosamines in the diet: occurrence, formation, mechanisms and carcinogenic potential. Mutat Res. 259:277–289.
   PubMed Web of Science ®Google Scholar
• [USDA] U.S. Department of Agriculture. 2011. U.S. Code of Federal Regulations, Food Safety and Inspection Service, Department of Agriculture, n. 424.22.
   Google Scholar
• Ventanas S, Martín D, Estévez M, Ruiz J. 2006. Analysis of volatile nitrosamines from a model system using SPME–DED at different temperatures and times of extraction. Food Chem. 99:842–850.
   Web of Science ®Google Scholar
• Yurchenko S, Mölder U. 2007. The occurrence of volatile N-nitrosamines in Estonian meat products. Food Chem. 100:1713–1721.
   Web of Science ®Google Scholar