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Food Additives & Contaminants: Part A Volume 34, 2017 - Issue 3
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Original Articles

Isolation and identification of a novel sildenafil analogue adulterant in herbal products

Ya-Tze LinDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei City, Taiwan (ROC)View further author information
,
Yen-Chun HuangDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei City, Taiwan (ROC)View further author information
,
Hui-Chun LeeDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei City, Taiwan (ROC)Correspondence[email protected]
View further author information
,
Chen-Hsiang LiaoDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei City, Taiwan (ROC)View further author information
,
Yun-Lian LinDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan (ROC)View further author information
,
Chia-Fen TsaiDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei City, Taiwan (ROC)View further author information
&
Hwei-Fang ChengDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei City, Taiwan (ROC)View further author information
 show all
Pages 330-334 | Received 04 Oct 2016, Accepted 11 Dec 2016, Published online: 23 Dec 2016

References

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  • Huang Y-C, Lee H-C, Lin Y-L, Li C-Y, Tsai C-F, Cheng H-F. 2016. Separation and identification of a novel tadalafil analogue adulterant in a dietary supplement. Food Additives Contaminants Part A. 33:179–185.
  • Lai K-C, Liu Y-C, Tseng M-C, Lin J-H. 2006. Isolation and identification of a sildenafil analogue illegally added in dietary supplements. J Food Drug Anal. 14:19–23.
  • Lai K-C, Liu Y-C, Tseng M-C, Lin Y-L, Lin J-H. 2007a. Isolation and identification of a vardenafil analogue in a functional food marketed for penile erectile dysfunction. J Food Drug Anal. 15:133–138.
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  • Shin MH, Hong MK, Kim WS, Lee YJ, Jeoung YC. 2003. Identification of a new analogue of sildenafil added illegally to a functional food marketed for penile erectile dysfunction. Food Addit Contam. 20:793–796.
  • Terrett NK, Bell AK, Brown D, Ellis P. 1996. Sildenafil (Viagra) a potent and selective inhibitor of type-5 cyclic GMP phosphodiesterase with utility for the treatment of male erectile dysfunction. Bioorg Med Chem Lett. 6:1819–1824.
  • Zou P, Oh SSY, Hou P, Chong YM, Bloodworth BC, Low MY, Koh HL. 2008. Isolation and identification of thiohomosildenafil and thiosildenafil in health supplements. J Pharm Biomed Anal. 47:279–284.

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