Occurrence of deoxynivalenol in an elderly cohort in the UK: a biomonitoring approach

References

• Barr DB, Wilder LC, Caudill SP, Gonzalez AJ, Needham LL, Pirkle JL. 2005. Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environ Health Perspect. 113(2):192–200.
   PubMed Web of Science ®Google Scholar
• Brera C, Santis B, Debegnach F, Miano B, Moretti G, Lanzone A, Del Sordo G, Buonsenso D, Chiaretti A, Hardie L, et al. 2015. Experimental study of deoxynivalenol biomarkers in urine. European Food Safety Authority (EFSA) Supporting Publications. EN–81. doi:10.2903/sp.efsa.2015.EN-818
   Google Scholar
• Bretz M, Beyer M, Cramer B, Knecht A, Humpf HU. 2006. Thermal degradation of the Fusarium mycotoxin deoxynivalenol. J Agric Food Chem. 54:6445–6451.
   PubMed Web of Science ®Google Scholar
• Bullerman LB, Bianchini A. 2007. Stability of mycotoxins during food processing. Int J Food Microbiol. 119(1–2):140–146.
   PubMed Web of Science ®Google Scholar
• Claesson MJ, Cusack S, O’Sullivan O, Greene-Diniz R, De Weerd H, Flannery E, Marchesi JR, Falush D, Dinan T, Fitzgerald G, et al. 2011. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci USA. 108(Suppl 1):4586–4591. doi:10.1073/pnas.1000097107
   PubMed Web of Science ®Google Scholar
• Clark ES, Flannery BM, Gardner EM, Pestka JJ. 2015. High sensitivity of aged mice to deoxynivalenol (vomitoxin)-induced anorexia corresponds to elevated proinflammatory cytokine and satiety hormone responses. Toxins (Basel). 7:4199–4215.
   PubMed Web of Science ®Google Scholar
• Drewnowski A. 2000. Sensory control of energy density at different life stages. Proc Nutr Soc. 59:239–244.
   PubMed Web of Science ®Google Scholar
• Etzel RA. 2006. What the primary care pediatrician should know about syndromes associated with exposures to mycotoxins. Curr Probl Pediatr Adolesc Health Care. 36:282–305.
   PubMedGoogle Scholar
• [EFSA] European Food Safety Authority. 2013. Deoxynivalenol in food and feed: occurrence and exposure. EFSA J. 11:2013.
   Google Scholar
• Ezekiel CN, Warth B, Ogara IM, Abia WA, Ezekiel VC, Atehnkeng J, Sulyok M, Turne PC, Tayo GO, Krska R, et al. 2014. Mycotoxin exposure in rural residents in northern Nigeria: a pilot study using multi-urinary biomarkers. Environ Int. 66:138–145.
   PubMed Web of Science ®Google Scholar
• Föllmann W, Ali N, Blaszkewicz M, Degen GH. 2016. Biomonitoring of mycotoxins in urine: pilot study in mill workers. J Toxicol Environ Health A. 79:1015–1025.
   PubMed Web of Science ®Google Scholar
• Gerding J, Ali N, Schwartzbord J, Cramer B, Brown DL, Degen GH, Humpf HU. 2015. A comparative study of the human urinary mycotoxin excretion patterns in Bangladesh, Germany, and Haiti using a rapid and sensitive LC-MS/MS approach. Mycotoxin Res. 31:127–136.
   PubMed Web of Science ®Google Scholar
• Gerding J, Cramer B, Humpf HU. 2014. Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approachю. Mol Nutr Food Res. 58(12):2358–2368.
   PubMed Web of Science ®Google Scholar
• Gratz SW, Richardson AJ, Duncan G, Holtrop G. 2014. Annual variation of dietary deoxynivalenol exposure during years of different Fusarium prevalence: a pilot biomonitoring study. Food Addit Contam Part Chem Anal Control Expo Risk Assess. 31(9):1579–1585.
   PubMed Web of Science ®Google Scholar
• Heyndrickx E, Sioen I, Huybrechts B, Callebaut A, De Henauw S, De Saeger S. 2015. Human biomonitoring of multiple mycotoxins in the Belgian population: results of the BIOMYCO study. Environ Int. 84:82–89.
   PubMed Web of Science ®Google Scholar
• [JECFA] Joint Expert Committee on Food and Additives. 2010. Evaluation of certain food additives and contaminants. In Report of the Seventy-Second Meeting of the Joint FAO/WHO Expert Committee on Food Additives. In WHO Technical Report Series, edited by World Health Organization.
   Google Scholar
• Mangoni AA, Jackson SH 2004. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol. 57(6–14). doi:10.1046/j.1365-2125.2003.02007.x
   Google Scholar
• Marin S, Ramos AJ, Cano-Sancho G, Sanchis V 2013. Mycotoxins: occurrence, toxicology, and exposure assessment. Food Chem Toxicol. 60(218–37). doi:10.1016/j.fct.2013.07.047
   PubMedGoogle Scholar
• Martone AM, Onder G, Vetrano DL, Ortolani E, Tosato M, Marzetti E, Landi F. 2013. Anorexia of aging: a modifiable risk factor for frailty. Nutrients. 5:4126–4133.
   PubMed Web of Science ®Google Scholar
• Oldenburg E, Schittenhelm S. 2012. Effect of plant water deficit on the deoxynivalenol concentration in Fusarium-infected maize kernels. Mycotoxin Res. 28(4):229–236.
   PubMedGoogle Scholar
• Papageorgiou M, Wells L, Williams C, White K, De Santis B, Liu Y, Debegnach F, Miano B, Moretti G, Greetham S, et al. 2018. Assessment of urinary deoxynivalenol biomarkers in UK children and adolescents. Toxins (Basel). 10(2):50. doi:10.3390/toxins10020050
   PubMed Web of Science ®Google Scholar
• Pestka JJ. 2010. Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance. Arch Toxicol. 84:663–679.
   PubMed Web of Science ®Google Scholar
• Pestka JJ, Smolinski AT. 2005. Deoxynivalenol: toxicology and potential effects on humans. J Toxicol Environ Health B Crit Rev. 8:39–69.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Carrasco Y, Molto JC, Manes J, Berrada H. 2014. Development of a GC-MS/MS strategy to determine 15 mycotoxins and metabolites in human urine. Talanta. 128:125–131.
   PubMed Web of Science ®Google Scholar
• Scudamore KA, Hazel CM, Patel S, Scriven F. 2009. Deoxynivalenol and other Fusarium mycotoxins in bread, cake, and biscuits produced from UK-grown wheat under commercial and pilot scale conditions. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 26:1191–1198.
   Web of Science ®Google Scholar
• Shephard GS, Burger HM, Gambacorta L, Gong YY, Krska R, Rheeder JP, Solfrizzo M, Srey C, Sulyok M, Visconti A, et al. 2013. Multiple mycotoxin exposure determined by urinary biomarkers in rural subsistence farmers in the former Transkei, South Africa. Food Chem Toxicol. 62:217–225.
   PubMed Web of Science ®Google Scholar
• Solfrizzo M, Gambacorta L, Visconti A. 2014. Assessment of multi-mycotoxin exposure in southern Italy by urinary multi-biomarker determination. Toxins (Basel). 6:523–538.
   PubMed Web of Science ®Google Scholar
• Talley NJ, O’Keefe EA, Zinsmeister AR, Melton LJ. 1992. Prevalence of gastrointestinal symptoms in the elderly: a population-based study. Gastroenterology. 102:895–901.
   PubMed Web of Science ®Google Scholar
• Turner PC, Burley VJ, Rothwell JA, White KL, Cade JE, Wild CP. 2008. Deoxynivalenol: rationale for development and application of a urinary biomarker. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 25:864–871.
   PubMed Web of Science ®Google Scholar
• Turner PC, Hopton RP, Lecluse Y, White KL, Fisher J, Cade JE, Wild CP. 2011a. Assessment of deoxynivalenol metabolite profiles in UK adults. Food Chem Toxicol. 49:132–135.
   PubMed Web of Science ®Google Scholar
• Turner PC, Hopton RP, Lecluse Y, White KL, Fisher J, Lebailly P. 2010a. Determinants of urinary deoxynivalenol and de-epoxy deoxynivalenol in male farmers from Normandy, France. J Agric Food Chem. 58:5206–5212.
   PubMed Web of Science ®Google Scholar
• Turner PC, Ji BT, Shu XO, Zheng W, Chow WH, Gao YT, Hardie LJ. 2011b. A biomarker survey of urinary deoxynivalenol in China: the Shanghai women’s health study. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 28:1220–1223.
   PubMed Web of Science ®Google Scholar
• Turner PC, White KL, Burley VJ, Hopton RP, Rajendram A, Fisher J, Cade JE, Wild CP. 2010b. A comparison of deoxynivalenol intake and urinary deoxynivalenol in UK adults. Biomarkers. 15:553–562.
   PubMed Web of Science ®Google Scholar
• Wakimoto P, Block G. 2001. Dietary intake, dietary patterns, and changes with age: an epidemiological perspective. J Gerontol A Biol Sci Med Sci. 56:65–80.
   PubMed Web of Science ®Google Scholar
• Wallin S, Gambacorta L, Kotova N, Lemming EW, Nalsen C, Solfrizzo M, Olsen M. 2015. Biomonitoring of concurrent mycotoxin exposure among adults in Sweden through urinary multi-biomarker analysis. Food Chem Toxicol. 83:133–139.
   PubMed Web of Science ®Google Scholar
• Warth B, Sulyok M, Fruhmann P, Berthiller F, Schuhmacher R, Hametner C, Adam G, Frohlich J, Krska R. 2012. Assessment of human deoxynivalenol exposure using an LC-MS/MS based biomarker method. Toxicol Lett. 211:85–90.
   PubMed Web of Science ®Google Scholar
• Wells L, Hardie L, Williams C, White K, Liu Y, De Santis B, Debegnach F, Moretti G, Greetham S, Brera C, et al. 2016. Determination of deoxynivalenol in the urine of pregnant women in the UK. Toxins (Basel). 8:306.
   Web of Science ®Google Scholar
• Wells L, Hardie L, Williams C, White K, Liu Y, De Santis B, Debegnach F, Moretti G, Greetham S, Brera C, et al. 2017. Deoxynivalenol biomarkers in the urine of UK vegetarians. Toxins (Basel). 9:196.
   Web of Science ®Google Scholar
• Wu Q, Dohnal V, Huang L, Kuca K, Yuan Z. 2010. Metabolic pathways of trichothecenes. Drug Metab Rev. 42:250–267.
   PubMed Web of Science ®Google Scholar