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Food Additives & Contaminants: Part A Volume 40, 2023 - Issue 5
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Articles

Quinolizidine alkaloids in lupine flour and lupine products from the German retail market and risk assessment of the results regarding human health

Oliver Keutha Institute of Food Chemistry, Westfälische Wilhelms-Universität, Münster, Germany;b Special Analytical Services, Chemical and Veterinary, Analytical Institute Münsterland-Emscher-Lippe-AöR, Münster, GermanyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9268-1274
ORCID Icon,
H. U. Humpfa Institute of Food Chemistry, Westfälische Wilhelms-Universität, Münster, Germany
&
Peter Fürsta Institute of Food Chemistry, Westfälische Wilhelms-Universität, Münster, Germany
Pages 667-674 | Received 23 Nov 2022, Accepted 20 Mar 2023, Published online: 03 Apr 2023

References

  • Australia New Zealand Food Authority (ANZFA). 2001. Lupin alkaloids in food: a toxicological review and risk assessment. Available from: https://www.foodstandards.gov.au/publications/documents/TR3.pdf
  • Boschin G, Annicchiarico P, Resta D, D'Agostina A, Arnoldi A. 2008. Quinolizidine alkaloids in seeds of lupine genotypes of different origins. J Agric Food Chem. 56(10):3657–3663. doi:10.1021/jf7037218
  • Bundesinstitut für Risikobewertung (BfR). 2017. Risikobewertung des Alkaloidvorkommens in Lupinensamen. Available from: https://www.bfr.bund.de/cm/343/risikobewertung-des-alkaloidvorkommens-in-lupinensamen.pdf.
  • European Commission. 2002. REGULATION (EC) No 178/2002 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety (last amended by 27.03.2021).
  • European Food Safety Authority (EFSA). 2019. Scientific opinion on the risks for animal and human health related to the presence of quinolizidine alkaloids in feed and food, in particular in lupins and lupin-derived products. EFSA J. 7(11):5860.
  • European Food Safety Authority (EFSA). 2021. The EFSA comprehensive European food consumption database [Internet]. [accessed 2022 Jan 06]. Available from: https://www.efsa.europa.eu/en/food-consumption/comprehensive-database.
  • Gry J, Pilegaard K. 2009. Alkaloids in edible lupin seeds: a toxicological review and recommendations. Copenhagen K: Nordic Council of Ministers.
  • Resta D, Boschin G, D'Agostina A, Arnoldi A. 2008. Evaluation of total quinolizidine alkaloids content in lupin flours, lupin-based ingredients, and foods. Mol Nutr Food Res. 52(4):490–495. doi:10.1002/mnfr.200700206
  • Wink M. 1987. Quinolizidine alkaloids: biochemistry, metabolism, and function in plants and cell suspension cultures. Planta Med. 53(6):509–514. doi:10.1055/s-2006-962797

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