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Review Article

Contaminant and residue profiles in Lebanese food: a comparative analysis with global standards

, , , , &
Received 17 Feb 2024, Accepted 26 Jun 2024, Published online: 22 Jul 2024

References

  • Abou Zeid MI, Jammoul AM, Melki KC, Jawdah YA, Awad MK. 2020. Suggested policy and legislation reforms to ­reduce deleterious effect of pesticides in Lebanon. Heliyon. 6(12):e05524. doi: 10.1016/j.heliyon.2020.e05524.
  • Al-Alam J, Fajloun Z, Chbani A, Millet M. 2017. A multiresidue method for the analysis of 90 pesticides, 16 PAHs, and 22 PCBs in honey using QuEChERS–SPME. Anal Bioanal Chem. 409(21):5157–5169. doi: 10.1007/s00216-017-0463-y.
  • Alegbeleye OO, Opeolu BO, Jackson VA. 2017. Polycyclic aromatic hydrocarbons: a critical review of environmental occurrence and bioremediation. Environ Manage. 60(4):758–783. doi: 10.1007/s00267-017-0896-2.
  • Ardic M, Karakaya Y, Atasever M, Durmaz H. 2008. Determination of aflatoxin B1 levels in deep-red ground pepper (isot) using immunoaffinity column combined with ELISA. Food Chem Toxicol. 46(5):1596–1599. doi: 10.1016/j.fct.2007.12.025.
  • Arfaeinia H, Cheshmazar E, Karimyan K, Darvishmotevalli M, Hashemi SE. 2018. Data on concentrations of polycyclic aromatic hydrocarbons (PAHs) in roasted and fried chicken – a case study: Bushehr, Iran. Data Brief. 21:1842–1847. doi: 10.1016/j.dib.2018.11.012.
  • Bacanlı M, Başaran N. 2019. Importance of antibiotic residues in animal food. Food Chem Toxicol. 125:462–466. doi: 10.1016/j.fct.2019.01.033.
  • Bansal V, Kim K-H. 2015. Review of PAH contamination in food products and their health hazards. Environ Int. 84:26–38. doi: 10.1016/j.envint.2015.06.016.
  • Bjørklund G, Chirumbolo S, Dadar M, Pivina L, Lindh U, Butnariu M, Aaseth J. 2019. Mercury exposure and its effects on fertility and pregnancy outcome. Basic Clin Pharmacol Toxicol. 125(4):317–327. doi: 10.1111/bcpt.13264.
  • Borjac J, el Joumaa M, Youssef L, Kawach R, Blake DA. 2020. Quantitative analysis of heavy metals and organic compounds in soil from Deir Kanoun Ras El Ain Dump, Lebanon. ScientificWorldJournal. 2020:8151676–10. doi: 10.1155/2020/8151676.
  • Brandt KK, Amézquita A, Backhaus T, Boxall A, Coors A, Heberer T, Lawrence JR, Lazorchak J, Schönfeld J, Snape JR, et al. 2015. Ecotoxicological assessment of antibiotics: a call for improved consideration of microorganisms. Environ Int. 85:189–205. doi: 10.1016/j.envint.2015.09.013.
  • Castillo M, Carbonell E, Gonzlez C, Miralles-Marco A. 2012. Pesticide residue analysis in animal origin food: procedure proposal and evaluation for lipophilic pesticides. In: Soundararajan RP, editor. Pesticides - recent trends in pesticide residue assay. InTech. doi: 10.5772/48665.
  • Damalas CA, Eleftherohorinos IG. 2011. Pesticide exposure, safety issues, and risk assessment indicators. Int J Environ Res Public Health. 8(5):1402–1419. doi: 10.3390/ijerph8051402.
  • Damalas CA, Koutroubas S. 2017. Farmers’ training on pesticide use is associated with elevated safety behavior. Toxics. 5(3):19. doi: 10.3390/toxics5030019.
  • Damalas CA, Koutroubas S. 2018. Current status and recent developments in biopesticide use. Agriculture. 8(1):13. doi: 10.3390/agriculture8010013.
  • Daou R, Hoteit M, Bookari K, Joubrane K, Khabbaz LR, Ismail A, Maroun RG, Khoury AE. 2022. Public health risk associated with the co-occurrence of aflatoxin B1 and ochratoxin A in spices, herbs, and nuts in Lebanon. Front Public Health. 10:1072727. doi: 10.3389/fpubh.2022.1072727.
  • Daou R, Joubrane K, Khabbaz LR, Maroun RG, Ismail A, El Khoury A. 2021. Aflatoxin B1 and ochratoxin A in imported and Lebanese wheat and -products. Food Addit Contam Part B Surveill. 14(3):227–235. doi: 10.1080/19393210.2021.1933203.
  • Darwish WS, Chiba H, El-Ghareeb WR, Elhelaly AE, Hui S-P. 2019. Determination of polycyclic aromatic hydrocarbon content in heat-treated meat retailed in Egypt: Health risk assessment, benzo[a]pyrene induced mutagenicity and oxidative stress in human colon (CaCo-2) cells and protection using rosmarinic and ascorbic acids. Food Chem. 290:114–124. doi: 10.1016/j.foodchem.2019.03.127.
  • [EFSA] European Food Safety Authority. 2007. Opinion of the Scientific Panel on contaminants in the food chain (CONTAM) related to hormone residues in bovine meat and meat products. EFSA J. 5(7):510. doi: 10.2903/j.efsa.2007.510.
  • Elaridi J, Fakhro M, Yamani O, Dimassi H, Othman H, Attieh Z. 2020. GC-MS analysis of polycyclic aromatic hydrocarbons in bottled olive oil marketed in Lebanon. Toxicol Res. 36(3):211–220. doi: 10.1007/s43188-019-00015-3.
  • Elaridi J, Yamani O, Al Matari A, Dakroub S, Attieh Z. 2019. Determination of ochratoxin A (OTA), ochratoxin B (OTB), T-2, and HT-2 toxins in wheat grains, wheat flour, and bread in Lebanon by LC-MS/MS. Toxins. 11(8):471. doi: 10.3390/toxins11080471.
  • El Daouk S, Pineau A, Taha M, Ezzeddine R, Hijazi A, Al Iskandarani M. 2020. Aluminum exposure from food in the population of Lebanon. Toxicol Rep. 7:1025–1031. doi: 10.1016/j.toxrep.2020.08.018.
  • Elgueta S, Fuentes M, Valenzuela M, Zhao G, Liu S, Lu H, Correa A. 2019. Pesticide residues in ready-to-eat leafy vegetables from markets of Santiago, Chile, and consumer’s risk. Food Addit Contam Part B Surveill. 12(4):259–267. doi: 10.1080/19393210.2019.1625975.
  • El Hawari K, Mokh S, Al Iskandarani M, Halloum W, Jaber F. 2019. Pesticide residues in Lebanese apples and health risk assessment. Food Addit Contam Part B Surveill. 12(2):81–89. doi: 10.1080/19393210.2018.1564370.
  • El Husseini M, Makkouk R, Rabaa A, Al Omar F, Jaber F. 2018. Determination of polycyclic aromatic hydrocarbons (PAH4) in the traditional Lebanese grilled chicken: ­implementation of new, rapid and economic analysis method. Food Anal Methods. 11(1):201–214. doi: 10.1007/s12161-017-0990-3.
  • El Husseini M, Mourad R, Abdul Rahim H, Al Omar F, Jaber F. 2021. Assessment of polycyclic aromatic hydrocarbons (PAH4) in the traditional Lebanese grilled meat products and investigation of broasted frying cooking method and meat size on the PAH4 formation. Polycyclic Aromat Compd. 41(1):124–142. doi: 10.1080/10406638.2019.1570952.
  • El Jai A, Juan C, Juan-García A, Mañes J, Zinedine A. 2021. Multi-mycotoxin contamination of green tea infusion and dietary exposure assessment in Moroccan population. Food Res Int. 140:109958. doi: 10.1016/j.foodres.2020.109958.
  • El Khoury, Andre, Daou, Rouaa, Atoui, Ali, Hoteit, Maha. 2022. Mycotoxins in Lebanese Food Basket: Database on Occurrence and Exposure. https://osf.io/7yjdg/ (Access date: 15/07/2024).
  • EU Regulation (EC) No 37/2010. 2010. Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin (Text with EEA Relevance). O J Eur Union . L.15:1–72.
  • EU Regulation (EC) No 149/2008. 2008. Commission Regulation (EC) No 149/2008 of 29 January 2008 Amending Regulation (EC) No 396/2005 of the European Parliament and of the Council by Establishing Annexes II, III AND IV Setting Maximum Residue Levels for Products Covered by Annex I Thereto (Text with EEA Relevance). L 58:1–398.
  • EU Regulation (EC) No 396/2005. 2005. Regulation (EC) No 396/2005 of the European Parliament and of the Council of 23 February 2005 on maximum residue levels of pesticides in or on food and feed of plant and animal origin and amending Council Directive 91/414/EEC. O J Eur Commun. L70:1–16.
  • EU Regulation (EC) No 835/2011. 2011. Commission Regulation (EU) No 835/2011 of 19 August 2011 amending Regulation (EC) No 1881/2006 as regards maximum levels for polycyclic aromatic hydrocarbons in foodstuffs Text with EEA relevance. O J Eur Union . L 215:4–8.
  • EU Regulation (EC) No 1107/2009. 2009. Regulation (EC) No 1107/2009 of the European Parliament and of the Council of 21 October 2009 concerning the placing of plant protection products on the market and repealing Council Directives 79/117/EEC and 91/414/EEC. O J Eur Union L. 309:1–50.
  • EU Regulation (EC) No 1327/2014. 2014. Regulation (EU) No 1327/2014 of 12 December 2014 amending regulation (EC) No 1881/2006 as regards maximum levels of polycyclic aromatic hydrocarbons (PAHs) in traditionally smoked meat and meat products and traditionally smoked fish and fishery products Text with EEA relevance. O J Eur Union. L358 13–14.
  • EU Regulation (EC) No 1881/2006. 2006. Commission regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. O J Eur Union L. 364:5–24.
  • EU Regulation (EC) No 2015/1933. 2015. Commission Regulation (EU) 2015/1933 of 27 October 2015 amending Regulation (EC) No 1881/2006 as regards maximum levels for polycyclic aromatic hydrocarbons in cocoa fibre, banana chips, food supplements, dried herbs and dried spices (Text with EEA relevance). O J Eur Union . L 282:11–13.
  • Faostats FAO. 2020. Statistical databases. Food and Agriculture Organization of the United Nations. [accessed 2024 Jul 15]. https://www.fao.org/faostat/en/.
  • FAO/WHO Codex Alimentarius. 1995. Codex general standard for contaminants and toxins in food and feed CXS 193-1995. [accessed 2024 Jul 15]. https://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FStandards%252FCXS%2B193-1995%252FCXS_193e.pdf.
  • FAO/WHO Codex Alimentarius. 2021. Food standards programme, The 14th Session of the Codex Committee on Contaminants in Foods CF/14 INF/1. https://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-735-14%252FINFO-DOC%252FCF14_INF01x.pdf
  • Farah R, Lahoud N, Salameh P, Saleh N. 2015. Antibiotic dispensation by Lebanese pharmacists: a comparison of higher and lower socio-economic levels. J Infect Public Health. 8(1):37–46. doi: 10.1016/j.jiph.2014.07.003.
  • Gammone MA, Riccioni G, Parrinello G, D’Orazio N. 2018. Omega-3 polyunsaturated fatty acids: benefits and endpoints in sport. Nutrients. 11(1):46. doi: 10.3390/nu11010046.
  • Giray B, Girgin G, Engin AB, Aydın S, Sahin G. 2007. Aflatoxin levels in wheat samples consumed in some regions of Turkey. Food Control. 18(1):23–29. doi: 10.1016/j.foodcont.2005.08.002.
  • Glasdam S-M, Glasdam S, Peters GH. 2016. The importance of magnesium in the human body: a systematic literature review. Adv Clin Chem. 73:169–193. doi: 10.1016/bs.acc.2015.10.002.
  • Gonçalves A, Gkrillas A, Dorne JL, Dall’Asta C, Palumbo R, Lima N, Battilani P, Venâncio A, Giorni P. 2019. Pre- and postharvest strategies to minimize mycotoxin contamination in the rice food chain. Compr Rev Food Sci Food Saf. 18(2):441–454. doi: 10.1111/1541-4337.12420.
  • Gorzynik-Debicka M, Przychodzen P, Cappello F, Kuban-Jankowska A, Marino Gammazza A, Knap N, Wozniak M, Gorska-Ponikowska M. 2018. Potential health benefits of olive oil and plant polyphenols. Int J Mol Sci. 19(3):686. doi: 10.3390/ijms19030686.
  • Guo W, Pan B, Sakkiah S, Yavas G, Ge W, Zou W, Tong W, Hong H. 2019. Persistent organic pollutants in food: contamination sources, health effects and detection methods. Int J Environ Res Public Health. 16(22):4361. doi: 10.3390/ijerph16224361.
  • Habib A, Javed I, Muhammad N. 2005. Analysis of some residual antibiotics in muscle, kidney and liver samples of broiler chicken by various methods. Proceeding Pakistan Acad Sci. 42(4):223–231.
  • Hassan HF, Koaik L, Khoury AE, Atoui Ali, El Obeid T, Karam L. 2022. Dietary exposure and risk assessment of mycotoxins in thyme and thyme-based products marketed in Lebanon. Toxins. 14(5):331. doi: 10.3390/toxins14050331.
  • Hassan HF, Tashani H, Ballouk F, Daou R, El Khoury A, Abiad MG, AlKhatib A, Hassan M, El Khatib S, Dimassi H. 2023. Aflatoxins and ochratoxin A in tea sold in Lebanon: effects of type, packaging, and origin. Int J Environ Res Public Health. 20(16):6556. doi: 10.3390/ijerph20166556.
  • Hathout AS, Abel-Fattah SM, Abou-Sree YH, Fouzy ASM. 2020. Incidence and exposure assessment of aflatoxins and ochratoxin A in Egyptian wheat. Toxicol Rep. 7:867–873. doi: 10.1016/j.toxrep.2020.07.003.
  • Helou K, Harmouche-Karaki M, Karake S, Narbonne J-F. 2019. A review of organochlorine pesticides and polychlorinated biphenyls in Lebanon: environmental and ­human contaminants. Chemosphere. 231:357–368. doi: 10.1016/j.chemosphere.2019.05.109.
  • Hernández Hierro JM, Garcia-Villanova RJ, Rodríguez Torrero P, Toruño Fonseca IM. 2008. Aflatoxins and ochratoxin A in red paprika for retail sale in Spain: ­occurrence and evaluation of a simultaneous analytical method. J Agric Food Chem. 56(3):751–756. doi: 10.1021/jf073002c.
  • [IDAL] Investment Development Authority of Lebanon. 2020. Agriculture sector in Lebanon. [accessed 2024 Jul 15]. http://investinlebanon.gov.lb/Content/uploads/Publication/200402102635557∼IDAL%20Agrifood%20Industry%20in%20Lebanon%20Factbook%202020.pdf.
  • Ismail A, Akhtar S, Riaz M, Gong YY, Routledge MN, Naeem I. 2020. Prevalence and exposure assessment of aflatoxins through black tea consumption in the Multan City of Pakistan and the impact of tea making process on aflatoxins. Front Microbiol. 11:446. doi: 10.3389/fmicb.2020.00446.
  • Ismail G, El Hawari K, Jaber F, Verdon E, Al Iskandarani M. 2023. Optimization of a multi-residue screening method for the detection of 71 antimicrobial residues in milk products: the case of labneh. Food Anal Methods. 16(9-10):1512–1528. doi: 10.1007/s12161-023-02513-5.
  • Jammoul A, el Darra N. 2019. Evaluation of antibiotics residues in chicken meat samples in Lebanon. Antibiotics. 8(2):69. doi: 10.3390/antibiotics8020069.
  • Jayaraj R, Megha P, Sreedev P. 2016. Review article. Organochlorine pesticides, their toxic effects on living ­organisms and their fate in the environment. Interdiscip Toxicol. 9(3-4):90–100. doi: 10.1515/intox-2016-0012.
  • Jisr N, Younes G, el Omari K, Hamze M, Sukhn C, El-Dakdouki MH. 2020. Levels of heavy metals, total ­petroleum hydrocarbons, and microbial load in commercially valuable fish from the marine area of Tripoli, Lebanon. Environ Monit Assess. 192(11):705. doi: 10.1007/s10661-020-08672-w.
  • Kabata-Pendias A. 2010. Trace elements in soils and plants. 4th ed. Boca Raton: CRC Press. doi: 10.1201/b10158.
  • Kabrite S, Bou-Mitri C, Fares JEH, Hassan HF, Boumosleh JM. 2019. Identification and dietary exposure assessment of tetracycline and penicillin residues in fluid milk, yogurt, and labneh: a cross-sectional study in Lebanon. Vet World. 12(4):527–534. doi: 10.14202/vetworld.2019.527-534.
  • Kafouris D, Koukkidou A, Christou E, Hadjigeorgiou M, Yiannopoulos S. 2020. Determination of polycyclic aromatic hydrocarbons in traditionally smoked meat products and charcoal grilled meat in Cyprus. Meat Sci. 164:108088. doi: 10.1016/j.meatsci.2020.108088.
  • Kalaji HM, Rastogi A. 2007. Pharmaceutical compounds: an emerging pollutant (a review on plant-pharmaceuticals interaction). Chiang Mai J Sci. 44(2):287–297.
  • Kassem II, Nasser NA, Salibi J. 2020. Prevalence and loads of fecal pollution indicators and the antibiotic resistance phenotypes of Escherichia coli in raw minced beef in Lebanon. Foods. 9(11):1543. doi: 10.3390/foods9111543.
  • Kaur R, Mavi GK, Raghav S, Khan I. 2019. Pesticides ­classification and its impact on environment. IntJCurrMicrobiolAppSci. 8(03):1889–1897. doi: 10.20546/ijcmas.2019.803.224.
  • Khazaal S, El Darra N, Kobeissi A, Jammoul R, Jammoul A. 2022. Risk assessment of pesticide residues from foods of plant origin in Lebanon. Food Chem. 374:131676. doi: 10.1016/j.foodchem.2021.131676.
  • Khozam RB, Pohl P, Ayoubi B, al, Jaber F, Lobinski R. 2012. Toxic and essential elements in Lebanese cheese. Food Addit Contam Part B Surveill. 5(3):172–181. doi: 10.1080/19393210.2012.682611.
  • Kim K-H, Jahan SA, Kabir E, Brown RJC. 2013. A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects. Environ Int. 60:71–80. doi: 10.1016/j.envint.2013.07.019.
  • Kim M. 2012. Chemical contamination of red meat. In: Schrenk D, editor. Food science, technology and nutrition, chemical contaminants and residues in food. Woodhead Publishing; p. 447–468. doi: 10.1533/9780857095794.3.447.
  • Kojok HE, Khalil M, Hage R, Jammoul R, Jammoul A, Darra NE. 2022. Microbiological and chemical evaluation of dairy products commercialized in the Lebanese market. Vet World. 15(11):2575–2586. doi: 10.14202/vetworld.2022.2575-2586.
  • Lee S-Y, Lee J-Y, Shin H-S. 2015. Evaluation of chemical analysis method and determination of polycyclic aromatic ­hydrocarbons content from seafood and dairy products. Toxicol Res. 31(3):265–271. doi: 10.5487/TR.2015.31.3.265.
  • Marchese S, Polo A, Ariano A, Velotto S, Costantini S, Severino L. 2018. Aflatoxin B1 and M1: biological properties and their involvement in cancer development. Toxins. 10(6):214. doi: 10.3390/toxins10060214.
  • Martins ML, Martins HM, Bernardo F. 2001. Aflatoxins in spices marketed in Portugal. Food Addit Contam. 18(4):315–319. doi: 10.1080/02652030120041.
  • Matyaszek A, Szpyrka E, Podbielska M, Słowik-Borowiec M, Kurdziel A. 2013. Pesticide residues in berries harvested from South-Eastern Poland (2009-2011). Rocz Panstw Zakl Hig. 64(1):25–29.
  • McEwen SA, Collignon PJ. 2018. Antimicrobial resistance: a one health perspective. Microbiol Spectr. 6(2). doi: 10.1128/microbiolspec.ARBA-0009-2017.
  • Mojiri A, Zhou JL, Ohashi A, Ozaki N, Kindaichi T. 2019. Comprehensive review of polycyclic aromatic hydrocarbons in water sources, their effects and treatments. Sci Total Environ. 696:133971. doi: 10.1016/j.scitotenv.2019.133971.
  • Mokh S, Hawari K, El Rahim HA, Iskandarani MA, Jaber F. 2020. Antimicrobial residues survey by LC-MS in food-producing animals in Lebanon. Food Addit Contam Part B Surveill. 13(2):121–129. doi: 10.1080/19393210.2020.1739148.
  • Mokh S, Moussa F, Khoury EEL, Nassar R, Bernabò N, Al Iskandarani M. 2020. Development of a new liquid chromatography-tandem mass spectrometry method for the determination of hormones in bovine muscle. J Pharm Biomed Anal. 190:113550. doi: 10.1016/j.jpba.2020.113550.
  • Moreno-Rojas R, Sánchez-Segarra PJ, Cámara-Martos F, Amaro-López MA. 2010. Heavy metal levels in Spanish cheeses: influence of manufacturing conditions. Food Addit Contam Part B Surveill. 3(2):90–100. doi: 10.1080/19440049.2010.491838.
  • Moretti A, Logrieco AF, Susca A. 2017. Mycotoxins: an underhand food problem. Methods Mol Biol. 1542:3–12. doi: 10.1007/978-1-4939-6707-0_1.
  • Moussa F, Mokh S, Doumiati S, Barboni B, Bernabò N, Al Iskandarani M. 2020. LC-MS/MS method for the determination of hormones: validation, application and health risk assessment in various bovine matrices. Food Chem Toxicol. 138:111204. doi: 10.1016/j.fct.2020.111204.
  • Mtashobya LA. 2017. Assessment of pesticide residues in vegetables from the Western Usambara and Uruguru Mountains in Tanzania. Environ Monit Assess. 189(10):519. doi: 10.1007/s10661-017-6226-6.
  • Nasreddine L, Rehaime M, Kassaify Z, Rechmany R, Jaber F. 2016. Dietary exposure to pesticide residues from foods of plant origin and drinks in Lebanon. Environ Monit Assess. 188(8):485. doi: 10.1007/s10661-016-5505-y.
  • Noureddine El Moussawi S, Ouaini R, Matta J, Chébib H, Cladière M, Camel V. 2019. Simultaneous migration of bisphenol compounds and trace metals in canned vegetable food. Food Chem. 288:228–238. doi: 10.1016/j.foodchem.2019.02.116.
  • Olusola AV, Diana BE, Ayoade OI. 2012. Assessment of tetracycline, lead and cadmium residues in frozen chicken vended in Lagos and Ibadan, Nigeria. Pak J Biol Sci. 15(17):839–844. doi: 10.3923/pjbs.2012.839.844.
  • Onakpa MM, Njan AA, Kalu OC. 2018. A review of heavy metal contamination of food crops in Nigeria. Ann Glob Health. 84(3):488–494. doi: 10.29024/aogh.2314.
  • Palm LMN, Carboo D, Yeboah OP, Quasie WJ, Gorleku MA, Darko A. 2012. Characterization of polycyclic aromatic hydrocarbons (PAHs) present in smoked fish from Ghana. Adv J Food Sci Technol. 3(5):332–338.
  • Patel AB, Shaikh S, Jain KR, Desai C, Madamwar D. 2020. Polycyclic aromatic hydrocarbons: sources, toxicity, and remediation approaches. Front Microbiol. 11:562813. doi: 10.3389/fmicb.2020.562813.
  • Pérez-Lucas G, Vela N, el Aatik A, Navarro S. 2019. Environmental risk of groundwater pollution by pesticide leaching through the soil profile. In: Larramendy M, Soloneski S, editors. Pesticides - use and misuse and their impact in the environment. IntechOpen. doi: 10.5772/intechopen.82418.
  • Pirsaheb M, Fattahi N, Rahimi R, Sharafi K, Ghaffari HR. 2017. Evaluation of abamectin, diazinon and chlorpyrifos pesticide residues in apple product of Mahabad region gardens: Iran in 2014. Food Chem. 231:148–155. doi: 10.1016/j.foodchem.2017.03.120.
  • Pratiwi R, Ramadhanti SP, Amatulloh A, Megantara S, Subra L. 2023. Recent advances in the determination of veterinary drug residues in food. Foods. 12(18):3422. doi: 10.3390/foods12183422.
  • Price P, Zaleski R, Hollnagel H, Ketelslegers H, Han X. 2014. Assessing the safety of co-exposure to food packaging migrants in food and water using the maximum ­cumulative ratio and an established decision tree. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 31(3):414–421. doi: 10.1080/19440049.2013.865145.
  • Rai PK, Lee SS, Zhang M, Tsang YF, Kim K-H. 2019. Heavy metals in food crops: health risks, fate, mechanisms, and management. Environ Int. 125:365–385. doi: 10.1016/j.envint.2019.01.067.
  • Reinhold L, Reinhardt K. 2011. Mycotoxins in foods in Lower Saxony (Germany): results of official control analyses performed in 2009. Mycotoxin Res. 27(2):137–143. doi: 10.1007/s12550-011-0086-7.
  • Richardson JR, Fitsanakis V, Westerink RHS, Kanthasamy AG. 2019. Neurotoxicity of pesticides. Acta Neuropathol. 138(3):343–362. doi: 10.1007/s00401-019-02033-9.
  • Rogowska A, Pomastowski P, Sagandykova G, Buszewski B. 2019. Zearalenone and its metabolites: effect on human health, metabolism and neutralisation methods. Toxicon. 162:46–56. doi: 10.1016/j.toxicon.2019.03.004.
  • Romagnoli B, Menna V, Gruppioni N, Bergamini C. 2007. Aflatoxins in spices, aromatic herbs, herb-teas and medicinal plants marketed in Italy. Food Control. 18(6):697–701. doi: 10.1016/j.foodcont.2006.02.020.
  • Roy AK, Sinha KK, Chourasia HK. 1988. Aflatoxin contamination of some common drug plants. Appl Environ Microbiol. 54(3):842–843. doi: 10.1128/aem.54.3.842-843.1988.
  • Salama NA, Abou-Raya SH, Shalaby AR, Emam WH, Mehaya FM. 2011. Incidence of tetracycline residues in chicken meat and liver retailed to consumers. Food Addit Contam Part B Surveill. 4(2):88–93. doi: 10.1080/19393210.2011.585245.
  • Salameh P, Sacre H, Hallit S, Hajj A. 2017. Antibiotic resistance in Lebanon. AMR Control. [accessed 2024 Jul 15]. http://resistancecontrol.info/2017/antibiotic-resistance-in-lebanon/.
  • Salem NM, Ahmad R. 2010. Mycotoxins in food from Jordan: preliminary survey. Food Control. 21(8):1099–1103. doi: 10.1016/j.foodcont.2010.01.002.
  • Sallam KI, Abd‐Elghany SM, Mohammed MA. 2019. Heavy metal residues in some fishes from Manzala Lake, Egypt, and their health‐risk assessment. J Food Sci. 84(7):1957–1965. doi: 10.1111/1750-3841.14676.
  • Selim MI, Popendorf W, Ibrahim MS, Sharkawy SE, Kashory ESE. 1996. Anatoxin B1 in common Egyptian foods. J AOAC Int. 79(5):1124–1129. doi: 10.1093/jaoac/79.5.1124.
  • Sendón García R, Paseiro Losada P. 2004. Determination of bisphenol A diglycidyl ether and its hydrolysis and chlorohydroxy derivatives by liquid chromatography-mass spectrometry. J Chromatogr A. 1032(1-2):37–43. doi: 10.1016/j.chroma.2003.10.039.
  • Shahbazi Y, Ahmadi F, Fakhari F. 2016. Voltammetric determination of Pb, Cd, Zn, Cu and Se in milk and dairy products collected from Iran: an emphasis on permissible limits and risk assessment of exposure to heavy metals. Food Chem. 192:1060–1067. doi: 10.1016/j.foodchem.2015.07.123.
  • Shundo L, de Almeida AP, Alaburda J, Lamardo LCA, Navas SA, Ruvieri V, Sabino M. 2009. Aflatoxins and ochratoxin A in Brazilian paprika. Food Control. 20(12):1099–1102. doi: 10.1016/j.foodcont.2009.02.008.
  • Skrajnowska D, Bobrowska-Korczak B. 2019. Role of zinc in immune system and anti-cancer defense mechanisms. Nutrients. 11(10):2273. doi: 10.3390/nu11102273.
  • Slavin JL, Lloyd B. 2012. Health benefits of fruits and vegetables. Adv Nutr. 3(4):506–516. doi: 10.3945/an.112.002154.
  • Soubra L, Sarkis D, Hilan C, Verger P. 2009. Occurrence of total aflatoxins, ochratoxin A and deoxynivalenol in foodstuffs available on the Lebanese market and their impact on dietary exposure of children and teenagers in Beirut. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 26(2):189–200. doi: 10.1080/02652030802366108.
  • Stasinos S, Nasopoulou C, Tsikrika C, Zabetakis I. 2014. The bioaccumulation and physiological effects of heavy metals in carrots, onions, and potatoes and dietary implications for Cr and Ni: a review. J Food Sci. 79(5):R765–R780. doi: 10.1111/1750-3841.12433.
  • Suratman S, Edwards JW, Babina K. 2015. Organophosphate pesticides exposure among farmworkers: pathways and risk of adverse health effects. Rev Environ Health. 30(1):65–79. doi: 10.1515/reveh-2014-0072.
  • Tabarani A, Zinedine A, Bouchriti N, Abdennebi EH. 2020. Exposure assessment to ochratoxin A through the intake of three cereal derivatives from the Moroccan market. Food Res Int. 137:109464. doi: 10.1016/j.foodres.2020.109464.
  • Takım K, Aydemir ME. 2021. Aflatoxin analysis by LC-MS of local and imported black tea sold in Turkey. Int J Agric Environ Food Sci. 5(4):640–644. doi: 10.31015/jaefs.2021.4.24.
  • Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ. 2012. Heavy metal toxicity and the environment. Exp Suppl. 101:133–164. doi: 10.1007/978-3-7643-8340-4_6.
  • Thompson LA, Darwish WS. 2019. Environmental chemical contaminants in food: review of a global problem. J Toxicol. 2019:2345283–2345314. doi: 10.1155/2019/2345283.
  • Torović L. 2018. Aflatoxins and ochratoxin A in flour: a survey of the Serbian retail market. Food Addit Contam Part B Surveill. 11(1):26–32. doi: 10.1080/19393210.2017.1391335.
  • Touraud E. 2008. Knowledge and need assessment on pharmaceutical product in environmental waters. [accessed 2024 Jul 15]. https://cordis.europa.eu/docs/results/36/36864/124584761-6_en.pdf.
  • Tunick MH, van Hekken DL. 2015. Dairy products and health: recent Insights. J Agric Food Chem. 63(43):9381–9388. doi: 10.1021/jf5042454.
  • United Nations Environment Programme. 2009. The Stockholm convention on persistent organic pollutants. [accessed 2024 Jul 15]. https://wedocs.unep.org/20.500.11822/27568.
  • Van Boeckel TP, Glennon EE, Chen D, Gilbert M, Robinson TP, Grenfell BT, Levin SA, Bonhoeffer S, Laxminarayan R. 2017. Reducing antimicrobial use in food animals. Science. 357(6358):1350–1352. doi: 10.1126/science.aao1495.
  • Wang J, Hasanalieva G, Wood L, Markellou E, Iversen PO, Bernhoft A, Seal C, Baranski M, Vigar V, Ernst L, et al. 2020. Effect of wheat species (Triticum aestivum vs T. spelta), farming system (organic vs conventional) and flour type (wholegrain vs white) on composition of wheat flour; results of a retail survey in the UK and Germany – 1. Mycotoxin content. Food Chem. 327:127011. doi: 10.1016/j.foodchem.2020.127011.
  • [WHO] World Health Organization. 2015. WHO estimates of the global burden of foodborne diseases. [accessed 2024 Jul 15]. https://apps.who.int/iris/bitstream/handle/10665/199350/9789241565165_eng.pdf?sequence=1.
  • Abou Zeid MI, Awad MK, Melki KC, Jawdah YA, Jammoul AM. 2021. Pesticides residues on Loquat: a minor crop in Lebanon. Food Control. 130:108297. doi: 10.1016/j.foodcont.2021.108297.
  • Al Ghoul L, Abiad MG, Jammoul A, Matta J, El Darra N. 2020. Zinc, aluminium, tin and Bis-phenol a in canned tuna fish commercialized in Lebanon and its human health risk assessment. Heliyon. 6(9):e04995 doi: 10.1016/j.heliyon.2020.e04995.
  • Widmer RJ, Flammer AJ, Lerman LO, Lerman A. 2015. The Mediterranean diet, its components, and cardiovascular disease. Am J Med. 128(3):229–238. doi: 10.1016/j.amjmed.2014.10.014.
  • Yang Y, Shao B, Zhang J, Wu Y, Duan H. 2009. Determination of the residues of 50 anabolic hormones in muscle, milk and liver by very-high-pressure liquid chromatography–electrospray ionization tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 877(5-6):489–496. doi: 10.1016/j.jchromb.2008.12.054.
  • Zheng N, Wang J, Han R, Xu X, Zhen Y, Qu X, Sun P, Li S, Yu Z. 2013. Occurrence of several main antibiotic residues in raw milk in 10 provinces of China. Food Addit Contam Part B Surveill. 6(2):84–89. doi: 10.1080/19393210.2012.727189.
  • Zinedine A, Brera C, Elakhdari S, Catano C, Debegnach F, Angelini S, De Santis B, Faid M, Benlemlih M, Minardi V, et al. 2006. Natural occurrence of mycotoxins in cereals and spices commercialized in Morocco. Food Control. 17(11):868–874. doi: 10.1016/j.foodcont.2005.06.001.

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