167
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

Considering Over-Dispersion in the Sample Size Calculation for Clinical Trials With Repeated Count Measurements

&
Pages 283-291 | Received 04 Apr 2018, Accepted 12 Jan 2019, Published online: 13 May 2019

References

  • Amatya, A., Bhaumik, D., and Gibbons, R. D. (2013), “Sample Size Determination for Clustered Count Data,” Statistics in Medicine, 32, 4162–4179. DOI: 10.1002/sim.5819.
  • Cox, D. R. (1983), “Some Remarks on Overdispersion,” Biometrika, 70, 269–274. DOI: 10.1093/biomet/70.1.269.
  • Dean, C. B. (1992), “Testing for Overdispersion in Poisson and Binomial Regression Models,” Journal of the American Statistical Association, 87, 451–457. DOI: 10.1080/01621459.1992.10475225.
  • Erhardt, V., and Czado, C. (2010), “A Method for Approximately Sampling High-Dimensional Count Variables With Pre-Specified Pearson Correlation,” Technical Report.
  • Garcia, H. H., Pretell, E. J., Gilman, R. H., Martinez, S. M., Moulton, L. H., Del Brutto, O. H., Herrera, G., Evans, C. A., and Gonzalez, A. E. (2004), “A Trial of Antiparasitic Treatment to Reduce the Rate of Seizures Due to Cerebral Cysticercosis,” New England Journal of Medicine, 350, 249–258. DOI: 10.1056/NEJMoa031294.
  • Liang, K.-Y., and Zeger, S. L. (1986), “Longitudinal Data Analysis Using Generalized Linear Models,” Biometrika, 73, 13–22. DOI: 10.1093/biomet/73.1.13.
  • Liu, H., and Wu, T. (2008), “Sample Size Calculation and Power Analysis of Changes in Mean Response Over Time,” Communications in Statistics—Simulation and Computation, 37, 1785–1798. DOI: 10.1080/03610910802178380.
  • Lou, Y., Cao, J., Zhang, S., and Ahn, C. (2017), “Sample Size Estimation for a Two-Group Comparison of Repeated Count Outcomes Using GEE,” Communications in Statistics—Theory and Methods, 46, 6743–6753. DOI: 10.1080/03610926.2015.1134572.
  • Ogungbenro, K., and Aarons, L. (2010), “Sample Size/Power Calculations for Population Pharmacodynamic Experiments Involving Repeated-Count Measurements,” Journal of Biopharmaceutical Statistics, 20, 1026–1042. DOI: 10.1080/10543401003619205.
  • Patel, H. I., and Rowe, E. (1999), “Sample Size for Comparing Linear Growth Curves,” Journal of Biopharmaceutical Statistics, 9, 339–350. DOI: 10.1081/BIP-100101180.
  • Rochon, J. (1998), “Application of GEE Procedures for Sample Size Calculations in Repeated Measures Experiments,” Statistics in Medicine, 17, 1643–1658.
  • Tang, Y. (2015), “Sample Size Estimation for Negative Binomial Regression Comparing Rates of Recurrent Events With Unequal Follow-Up Time,” Journal of Biopharmaceutical Statistics, 25, 1100–1113. DOI: 10.1080/10543406.2014.971167.
  • Thall, P. F., and Vail, S. C. (1990), “Some Covariance Models for Longitudinal Count Data With Overdispersion,” Biometrics, 46, 657–671.
  • Thanarajasingam, G., Atherton, P. J., Novotny, P. J., Loprinzi, C. L., Sloan, J. A. and Grothey, A. (2016), “Longitudinal Adverse Event Assessment in oncology Clinical Trials: The Toxicity Over Time (ToxT) Analysis of Alliance Trials NCCTG N9741 and 979254,” The Lancet Oncology, 17, 663–670. DOI: 10.1016/S1470-2045(16)00038-3.
  • Zeileis, A., Kleiber, C., and Jackman, S. (2008), “Regression Models for Count Data in R,” Journal of Statistical Software, 27, 1–25.
  • Zhang, S., and Ahn, C. (2012), “Sample Size Calculation for Time-Averaged Differences in the Presence of Missing Data,” Contemporary Clinical Trials, 33, 550–556.
  • Zhu, H., and Lakkis, H. (2014), “Sample Size Calculation for Comparing Two Negative Binomial Rates,” Statistics in Medicine, 33, 376– 387. DOI: 10.1002/sim.5947.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.