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Original Articles

“Inflammaging” and Estradiol among Older U.S. Women: A Nationally Representative Longitudinal Study

References

  • Abu-Taha, M., C. Rius, C. Hermenegildo, I. Noguera, J. M. Cerda-Nicolas, A. C. Issekutz, P. J. Jose, J. Cortijo, E. J. Morcillo, and M.-J. Sanz. 2009. Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan. Journal of Immunology 183:1393–402. doi:10.4049/jimmunol.0803157.
  • Allison, P. D. 1990. Change scores as dependent variables in regression analysis. Sociological Methodology 20:93–114. doi:10.2307/271083.
  • Au, A., A. Feher, L. McPhee, A. Jessa, S. Oh, and G. Einstein. 2016. Estrogens, inflammation and cognition. Frontiers in Neuroendocrinology 40:87–100. doi:10.1016/j.yfrne.2016.01.002.
  • Beery, A. K., and I. Zucker. 2011. Sex bias in neuroscience and biomedical research. Neuroscience & Biobehavioral Reviews 35:565–72. doi:10.1016/j.neubiorev.2010.07.002.
  • Butcher, S. K., and J. M. Lord. 2004. Stress responses and innate immunity: Aging as a contributory factor. Aging Cell 3:151–60. doi:10.1111/ace.2004.3.issue-4.
  • Cioffi, M., K. Esposito, M. T. Vietri, P. Gazzerro, A. D’Auria, I. Ardovino, G. A. Puca, and A. M. Molinari. 2002. Cytokine pattern in postmenopause. Maturitas 41:187–92. doi:10.1016/S0378-5122(01)00286-9.
  • Cohen, J. 1988. Statistical power analysis for the behavioral sciences. 2nd ed. Mahwah, NJ: Lawrence Erlbaum Associates.
  • Crimmins, E., J. K. Kim, H. McCreath, J. Faul, D. Weir, and T. Seeman. 2014. Validation of blood-based assays using dried blood spots for use in large population studies. Biodemography and Social Biology 60:38–48. doi:10.1080/19485565.2014.901885.
  • Das, A. 2016. Psychosocial distress and inflammation: Which way does causality flow? Social Science and Medicine 170:1–8. doi:10.1016/j.socscimed.2016.10.001.
  • Das, A., E. O. Laumann, and L. J. Waite. 2012. Sexual expression over the life course: Results from three landmark surveys. In Sexualities over the life course: Emerging perspectives, eds. J. DeLamater and L. Carpenter, 236–59. New York: New York University Press.
  • Eskes, T., and C. Haanen. 2007. Why do women live longer than men? European Journal of Obstetrics Gynecology and Reproductive Biology 133:126–33. doi:10.1016/j.ejogrb.2007.01.006.
  • Fagiolo, U., A. Cossarizza, E. Scala, E. Fanales-Belasio, C. Ortolani, E. Cozzi, D. Monti, C. Franceschi, and R. Paganelli. 1993. Increased cytokine production in mononuclear cells of healthy elderly people. European Journal of Immunolology 23:2375–78. doi:10.1002/(ISSN)1521-4141.
  • Ferrucci, L., A. Corsi, F. Lauretani, S. Bandinelli, B. Bartali, D. D. Taub, J. M. Guralnik, and D. L. Longo. 2005. The origins of age-related proinflammatory state. Blood 105:2294–99. doi:10.1182/blood-2004-07-2599.
  • Finch, C. E. 2010. The biology of human longevity: Inflammation, nutrition, and aging in the evolution of lifespans. Burlington, MA: Academic.
  • Franceschi, C. 2007. Inflammaging as a major characteristic of old people: Can it be prevented or cured? Nutrition Reviews 65:S173–S176. doi:10.1301/nr.2007.dec.S173-S176.
  • Franceschi, C., and J. Campisi. 2014. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 69:S4–S9. doi:10.1093/gerona/glu057.
  • Fuente-Martin, E., C. Garcia-Caceres, E. Morselli, D. J. Clegg, J. A. Chowen, B. Finan, R. D. Brinton, and M. H. Tschöp. 2013. Estrogen, astrocytes and the neuroendocrine control of metabolism. Reviews in Endocrine and Metabolic Disorders 14:331–38. doi:10.1007/s11154-013-9263-7.
  • Gameiro, C. M., F. Romão, and C. Castelo-Branco. 2010. Menopause and aging: Changes in the immune system – A review. Maturitas 67:316–20. doi:10.1016/j.maturitas.2010.08.003.
  • Goto, M. 2008. Inflammaging (inflammation + aging): A driving force for human aging based on an evolutionarily antagonistic pleiotropy theory? BioScience Trends 2:218–30.
  • Granger, D. A., K. T. Kivlighan, C. Fortunato, A. G. Harmon, L. C. Hibel, E. B. Schwartz, and G.-L. Whembolua. 2007. Integration of salivary biomarkers into developmental and behaviorally-oriented research: Problems and solutions for collecting specimens. Physiology and Behavior 92:583–90. doi:10.1016/j.physbeh.2007.05.004.
  • Grodstein, F., J. E. Manson, M. J. Stampfer, and K. Rexrode. 2008. Postmenopausal hormone therapy and stroke: Role of time since menopause and age at initiation of hormone therapy. Archives of Internal Medicine 168:861–66. doi:10.1001/archinte.168.8.861.
  • Gröschl, M., R. Wagner, M. Rauh, and H. G. Dörr. 2001. Stability of salivary steroids: The influences of storage, food and dental care. Steroids 66:737–41. doi:10.1016/S0039-128X(01)00111-8.
  • Klein, S. L., and K. L. Flanagan. 2016. Sex differences in immune responses. Nature Reviews Immunology 16:626–38. doi:10.1038/nri.2016.90.
  • Kovacs, E. J. 2005. Aging, traumatic injury, and estrogen treatment. Experimental Gerontology 40:549–55. doi:10.1016/j.exger.2005.04.009.
  • Kozloski, M. J., L. P. Schumm, and M. K. McClintock. 2014. The utility and dynamics of salivary sex hormone measurements in the National Social Life, Health, and Aging Project, Wave 2. Journals of Gerontology Series B: Psychological Sciences and Social Sciences 69:S215–S228. doi:10.1093/geronb/gbu123.
  • Martin, W. S. 1978. Effect of scaling on the correlation coefficient: Additional considerations. Journal of Marketing Research 15:304–08. doi:10.2307/3151268.
  • Matthews, K. A., S. L. Crawford, C. U. Chae, S. A. Everson-Rose, M. F. Sowers, B. Sternfeld, and K. Sutton-Tyrrell. 2009. Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition? Journal of the American College of Cardiology 54:2366–73. doi:10.1016/j.jacc.2009.10.009.
  • McDade, T. W. 2005. The ecologies of human immune function. Annual Review of Anthropology 34:495–521. doi:10.1146/annurev.anthro.34.081804.120348.
  • McDade, T. W. 2010. Toward a new human population biology: The developmental origins of inflammation as case study. Paper presented at Fall 2010 Demography Workshop, Harris School of Public Policy Studies, University of Chicago.
  • McDade, T. W., J. Burhop, and J. Dohnal. 2004. High-sensitivity enzyme immunoassay for C-reactive protein in dried blood spots. Clinical Chemistry 50:652–54. doi:10.1373/clinchem.2003.029488.
  • Miller, A. P., Y. F. Chen, D. Xing, S. Feng, and S. Oparil. 2003. Hormone replacement therapy and inflammation: Interaction in cardiovascular disease. Hypertension 42:657–63. doi:10.1161/01.HYP.0000085560.02979.0C.
  • Miller, V. M., L. T. Shuster, and S. N. Hayes. 2003. Controversy of hormone treatment and cardiovascular function: Need for strengthened collaborations between preclinical and clinical scientists. Current Opinion in Investigational Drugs 4:1220–32.
  • O’Doherty, K., A. Jaszczak, J. N. Hoffmann, H. M. You, D. W. Kern, K. Pagel, J. McPhillips, L. P. Schumm, W. Dale, E. S. Huang, and M. K. McClintock. 2014. Survey field methods for expanded biospecimen and biomeasure collection in NSHAP Wave 2. Journals of Gerontology Series B: Psychological Sciences and Social Sciences 69:S27–S37. doi:10.1093/geronb/gbu045.
  • O’Muircheartaigh, C., N. English, S. Pedlow, and P. K. Kwok. 2014. Sample design, sample augmentation, and estimation for Wave 2 of the NSHAP. Journals of Gerontology Series B: Psychological Sciences and Social Sciences 69:S15–S26. doi:10.1093/geronb/gbu053.
  • Ostan, R., L. Bucci, M. Capri, S. Salvioli, M. Scurti, E. Pini, D. Monti, and C. Franceschi. 2008. Immunosenescence and immunogenetics of human longevity. NeuroImmunoModulation 15:224–40. doi:10.1159/000156466.
  • Ostan, R., D. Monti, P. Gueresi, M. Bussolotto, C. Franceschi, and G. Baggio. 2016. Gender, aging and longevity in humans: An update of an intriguing/neglected scenario paving the way to a gender-specific medicine. Clinical Science 130:1711–25. doi:10.1042/CS20160004.
  • Pearson, T. A., G. A. Mensah, R. W. Alexander, J. L. Anderson, R. O. Cannon III, M. Criqui, Y. Y. Fadi, S. P. Fortmann, Y. Hong, G. L. Myers, N. Rifai, S. C. Smith, Jr., K. Taubert, R. P. Tracy, F. Vinicor, Centers for Disease Control and Prevention, and American Heart Association. 2003. Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107:499–511.
  • Petrone, A. B., J. W. Simpkins, and T. L. Barr. 2014. 17β-estradiol and inflammation: Implications for ischemic stroke. Aging and Disease 5:340–45.
  • Pfeilschifter, J., R. Köditz, M. Pfohl, and H. Schatz. 2002. Changes in proinflammatory cytokine activity after menopause. Endocrine Reviews 23:90–119. doi:10.1210/edrv.23.1.0456.
  • Pinti, M., V. Appay, J. Campisi, D. Frasca, T. Fülöp, D. Sauce, A. Larbi, B. Weinberger, and A. Cossarizza. 2016. Aging of the immune system: Focus on inflammation and vaccination. European Journal of Immunology 46:2286–301. doi:10.1002/eji.v46.10.
  • Prestwood, K. M., C. Unson, M. Kulldorff, and M. Cushman. 2004. The effect of different doses of micronized 17ß-estradiol on C-reactive protein, interleukin-6, and lipids in older women. Journals of Gerontolology Series A: Biological Sciences and Medical Sciences 59:827–32. doi:10.1093/gerona/59.8.M827.
  • Puzianowska-Kuźnicka, M., M. Owczarz, K. Wieczorowska-Tobis, P. Nadrowski, J. Chudek, P. Slusarczyk, A. Skalska, M. Jonas, E. Franek, and M. Mossakowska. 2016. Interleukin-6 and C-reactive protein, successful aging, and mortality: The PolSenior study. Immunity and Ageing 13 (21). doi:10.1186/s12979-016-0076-x.
  • Qato, D. M., L. P. Schumm, M. Johnson, A. Mihai, and S. T. Lindau. 2009. Medication data collection and coding in a home-based survey of older adults. Journals of Gerontology Series B: Psychological Sciences and Social Sciences 64:i86–i93. doi:10.1093/geronb/gbp036.
  • Russel, C. J., and P. Bobko. 1992. Moderated regression analysis and Likert scales: Too coarse for comfort. Journal of Applied Psychology 77:336–42. doi:10.1037/0021-9010.77.3.336.
  • Russel, C. J., J. K. Pinto, and P. Bobko. 1991. Appropriate moderated regression and inappropriate research strategy: A demonstration of information loss to scale coarseness. Applied Psychological Measurement 15:257–66. doi:10.1177/014662169101500305.
  • Störk, S., C. Von Schacky, and P. Angerer. 2002. The effect of 17β-estradiol on endothelial and inflammatory markers in postmenopausal women: A randomized, controlled trial. Atherosclerosis 165:301–07. doi:10.1016/S0021-9150(02)00242-3.
  • Weuve, J., C. Proust-Lima, M. C. Power, A. L. Gross, S. M. Hofer, R. Thiébaut, G. Chêne, M. M. Glymour, and C. Dufouil. 2015. Guidelines for reporting methodological challenges and evaluating potential bias in dementia research. Alzheimer’s and Dementia 11:1098–109. doi:10.1016/j.jalz.2015.06.1885.
  • Weuve, J., E. J. Tchetgen Tchetgen, M. M. Glymour, T. L. Beck, N. T. Aggarwal, R. S. Wilson, D. A. Evans, and C. F. Mendes De Leon. 2012. Accounting for bias due to selective attrition: The example of smoking and cognitive decline. Epidemiology 23:119–28. doi:10.1097/EDE.0b013e318230e861.
  • Williams, S. R., and T. W. McDade. 2009. The use of dried blood spot sampling in the National Social Life, Health, and Aging project. Journals of Geronotology Series B: Psychological Sciences and Social Sciences 64B:i131–i136. doi:10.1093/geronb/gbn022.
  • Xing, D., S. Nozell, Y.-F. Chen, F. Hage, and S. Oparil. 2009. Estrogen and mechanisms of vascular protection. Arteriosclerosis, Thrombosis, and Vascular Biology 29:289–95. doi:10.1161/ATVBAHA.108.182279.
  • Yang, Y. 2008. Social inequalities in happiness in the U.S. 1972-2004: An age-period-cohort analysis. American Sociological Review 73:204–26. doi:10.1177/000312240807300202.
  • Yang, Y., and M. Kozloski. 2011. Sex differences in age trajectories of physiological dysregulation: Inflammation, metabolic syndrome, and allostatic load. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 66:493–500. doi:10.1093/gerona/glr003.
  • Yang, Y. C., C. Boen, K. Gerken, T. Li, K. Schorpp, and K. M. Harris. 2016. Social relationships and physiological determinants of longevity across the human life span. Proceedings of the National Academy of Sciences of the United States of America 113:578–83.
  • Yasui, T., M. Maegawa, J. Tomita, Y. Miyatani, M. Yamada, H. Uemura, T. Matsuzaki, A. Kuwahara, M. Kamada, N. Tsuchiya, M. Yuzurihara, S. Takeda, and M. Irahara. 2007. Changes in serum cytokine concentrations during the menopausal transition. Maturitas 56:396–403. doi:10.1016/j.maturitas.2006.11.002.

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