Global transcriptional changes caused by an EDMD mutation correlate to tissue specific disease phenotypes in C. elegans

References

• Wang N, Stamenovic D. Contribution of intermediate filaments to cell stiffness, stiffening, and growth. Am J Physiol Cell Physiol 2000; 279:C188-94; PMID:10898730
   PubMed Web of Science ®Google Scholar
• Harada T, Swift J, Irianto J, Shin JW, Spinler KR, Athirasala A, Diegmiller R, Dingal PCDP, Ivanovska IL, Discher DE. Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. J Cell Biol 2014; 204:669-82; PMID:24567359; http://dx.doi.org/10.1083/jcb.201308029
   PubMed Web of Science ®Google Scholar
• Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PCDP, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, et al. Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation. Science 2013; 341:1240104; PMID:23990565; http://dx.doi.org/10.1126/science.1240104
   PubMed Web of Science ®Google Scholar
• Stuurman N, Heins S, Aebi U. Nuclear Lamins: Their Structure, Assembly, and Interactions. J Struct Biol 1998; 122:42-66; PMID:9724605; http://dx.doi.org/10.1006/jsbi.1998.3987
   PubMed Web of Science ®Google Scholar
• Machowska M, Piekarowicz K, Rzepecki R. Regulation of lamin properties and functions: does phosphorylation do it all? Open Biol 2015; 5:150094; PMID:26581574; http://dx.doi.org/10.1098/rsob.150094
   PubMed Web of Science ®Google Scholar
• Lehner CF. Differential expression of nuclear lamin proteins during chicken development. J Cell Biol 1987; 105:577-87; PMID:3301871; http://dx.doi.org/10.1083/jcb.105.1.577
   PubMed Web of Science ®Google Scholar
• Gruenbaum Y, Foisner R. Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation. Annu Rev 2015; 84:131-64
   Web of Science ®Google Scholar
• Gay S, Foiani M. Chapter Six – Nuclear Envelope and Chromatin, Lock and Key of Genome Integrity. Int Rev Cell Mol Biol 2015; 317:267-330; PMID:26008788; http://dx.doi.org/10.1016/bs.ircmb.2015.03.001
   PubMed Web of Science ®Google Scholar
• Bertrand AT, Chikhaoui K, Yaou R, Ben, Bonne G. Clinical and genetic heterogeneity in laminopathies. Biochem Soc Trans 2011; 39:1687-92; PMID:22103508; http://dx.doi.org/10.1042/BST20110670
   PubMed Web of Science ®Google Scholar
• Belaadi N, Aureille J, Guilluy C. Under Pressure: Mechanical Stress Management in the Nucleus. Cells 2016; 5:27; http://dx.doi.org/10.3390/cells5020027
   PubMed Web of Science ®Google Scholar
• Osmanagic-Myers S, Dechat T, Foisner R. Lamins at the crossroads of mechanosignaling. Genes Dev 2015; 29:225-37; PMID:25644599; http://dx.doi.org/10.1101/gad.255968.114
   PubMed Web of Science ®Google Scholar
• Prokocimer M, Davidovich M, Nissim-Rafinia M, Wiesel-Motiuk N, Bar DZ, Barken R, Meshorer E, Gruenbaum Y. Nuclear lamins: key regulators of nuclear structure and activities. J Cell Mol Med 2009; 13:1059-85; PMID: 19210577; http://dx.doi.org/10.1111/j.1582-4934.2008.00676.x
   PubMed Web of Science ®Google Scholar
• Dittmer TA, Misteli T. The lamin protein family. Genome Biol 2011; 12:1-14; http://dx.doi.org/10.1186/gb-2011-12-5-222
   Web of Science ®Google Scholar
• Patricia MD, Lammerding J. Broken nuclei – lamins, nuclear mechanics, and disease. Trends Cell Biol 2014; 24:247-56; PMID:24309562; http://dx.doi.org/10.1016/j.tcb.2013.11.004
   PubMed Web of Science ®Google Scholar
• Worman HJ. Nuclear lamins and laminopathies. J Pathol 2012; 226:316-25; PMID:21953297; http://dx.doi.org/10.1002/path.2999
   PubMed Web of Science ®Google Scholar
• Schreiber KH, Kennedy BK. When Lamins Go Bad: Nuclear Structure and Disease. Cell 2013; 152:1365-75; PMID:23498943; http://dx.doi.org/10.1016/j.cell.2013.02.015
   PubMed Web of Science ®Google Scholar
• Bonne G, Quijano-Roy S. Emery–Dreifuss muscular dystrophy, laminopathies, and other nuclear envelopathies. Handb Clin Neurol 2013; 113:1367-76; PMID:23622360; http://dx.doi.org/10.1016/B978-0-444-59565-2.00007-1
   PubMedGoogle Scholar
• Maggi L, Carboni N, Bernasconi P. Skeletal Muscle Laminopathies: A Review of Clinical and Molecular Features. Cells 2016; 5:33; http://dx.doi.org/10.3390/cells5030033
   Google Scholar
• Zwerger M, Yee Ho C, Lammerding J. Nuclear Mechanics in Disease. Annu Rev 2011; 13:397-428
   Web of Science ®Google Scholar
• Zuela N, Zwerger M, Levin T, Medalia O, Gruenbaum Y. Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation. J Cell Sci 2016; 9:1781-91; http://dx.doi.org/10.1242/jcs.184309
   Web of Science ®Google Scholar
• Mattout A, Pike BL, Towbin BD, Bank EM, Gonzalez-Sandoval A, Stadler MB, Meister P, Gruenbaum Y, Gasser SM. An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity. Curr Biol 2011; 21:1603-14; PMID:21962710; http://dx.doi.org/10.1016/j.cub.2011.08.030
   PubMed Web of Science ®Google Scholar
• Korfali N, Wilkie GS, Swanson SK, Srsen V, de las Heras J, Batrakou DG, Malik P, Zuleger N, Kerr ARW, Florens L, et al. The nuclear envelope proteome differs notably between tissues. Nucleus 2012; 3:552-64; PMID:22990521; http://dx.doi.org/10.4161/nucl.22257
   PubMed Web of Science ®Google Scholar
• Worman HJ, Schirmer EC. Nuclear membrane diversity: underlying tissue-specific pathologies in disease? Curr Opin Cell Biol 2015; 34:101-12; PMID:26115475; http://dx.doi.org/10.1016/j.ceb.2015.06.003
   PubMed Web of Science ®Google Scholar
• Bank EM, Gruenbaum Y. Caenorhabditis elegans as a model system for studying the nuclear lamina and laminopathic diseases. Nucleus 2011; 2:350-7; PMID:21970988; http://dx.doi.org/10.4161/nucl.2.5.17838
   PubMed Web of Science ®Google Scholar
• Liu J, Ben-Shahar TR, Riemer D, Treinin M, Spann P, Weber K, Fire A, Gruenbaum Y. Essential Roles for Caenorhabditis elegans Lamin Gene in Nuclear Organization, Cell Cycle Progression, and Spatial Organization of Nuclear Pore Complexes. Mol Biol Cell 2000; 11:3937-47; PMID:11071918; http://dx.doi.org/10.1091/mbc.11.11.3937
   PubMed Web of Science ®Google Scholar
• Wiesel N, Mattout A, Melcer S, Melamed-Book N, Herrmann H, Medalia O, Aebi U, Gruenbaum Y. Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins. Proc Natl Acad Sci USA 2008; 105:180-5; PMID:18162544; http://dx.doi.org/10.1073/pnas.0708974105
   PubMed Web of Science ®Google Scholar
• Bank EM, Ben-Harush K, Feinstein N, Medalia O, Gruenbaum Y. Structural and physiological phenotypes of disease-linked lamin mutations in C. elegans. J Struct Biol 2012; 177:106-12; PMID:22079399; http://dx.doi.org/10.1016/j.jsb.2011.10.009
   PubMed Web of Science ®Google Scholar
• Fidziańska A, Walczak E, Glinka Z, Religa G. Nuclear architecture remodelling in cardiomyocytes with. Folia Neuropathol 2008; 46:196-203; PMID:18825595
   PubMed Web of Science ®Google Scholar
• Gupta P, Bilinska ZT, Sylvius N, Boudreau E, Veinot JP, Labib S, Bolongo PM, Hamza A, Jackson T, Ploski R, et al. Genetic and ultrastructural studies in dilated cardiomyopathy patients: a large deletion in the lamin A/C gene is associated with cardiomyocyte nuclear envelope disruption. Basic Res Cardiol 2010; 105:365-77; PMID:20127487; http://dx.doi.org/10.1007/s00395-010-0085-4
   PubMed Web of Science ®Google Scholar
• Haun C, Alexander J, Stainier DY, Okkema PG. Rescue of Caenorhabditis elegans pharyngeal development by a vertebrate heart specification gene. Proc Natl Acad Sci 1998; 95:5072-5; PMID:9560230; http://dx.doi.org/10.1073/pnas.95.9.5072
   PubMed Web of Science ®Google Scholar
• Csoka AB, English SB, Simkevich CP, Ginzinger DG, Butte AJ, Schatten GP, Rothman FG, Sedivy JM. Genome-scale expression profiling of Hutchinson–Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell 2004; 3:235-43; PMID:15268757; http://dx.doi.org/10.1111/j.1474-9728.2004.00105.x
   PubMed Web of Science ®Google Scholar
• Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974; 77:71-94; PMID:4366476
   PubMed Web of Science ®Google Scholar
• Huang DW, Sherman BT, Zheng X, Yang J, Imamichi T, Stephens R, Lempicki RA. Extracting Biological Meaning from Large Gene Lists with DAVID. Curr Protoc Bioinforma Curr. Protoc. Bioinform 2009; 27:13.11.1-13.11.13; PMID: 19728287
   Google Scholar
• Udvardi MK, Czechowski T, Scheible W-R. Eleven Golden Rules of Quantitative RT-PCR. Plant Cell 2008; 20:1736-7; PMID:18664613; http://dx.doi.org/10.1105/tpc.108.061143
   PubMed Web of Science ®Google Scholar