Inhibitory effect of Ssanghwa-tang on bone loss in ovariectomized rats

References

• Asagiri , M and Takayanagi , H. 2007 . The molecular understanding of osteoclast differentiation . Bone. , 40 : 251 – 264 .
   PubMed Web of Science ®Google Scholar
• Boyle , WJ , Simonet , WS and Lacey , DL. 2003 . Osteoclast differentiation and activation . Nature. , 423 : 337 – 342 .
   PubMed Web of Science ®Google Scholar
• Branca , F. 2003 . Dietary phyto-oestrogens and bone health . Proc Nutr Soc. , 62 : 877 – 887 .
   PubMed Web of Science ®Google Scholar
• García Palacios , V , Robinson , LJ , Borysenko , CW , Lehmann , T , Kalla , SE and Blair , HC. 2005 . Negative regulation of RANKL-induced osteoclastic differentiation in RAW264.7 cells by estrogen and phytoestrogens . J Biol Chem. , 280 : 13720 – 13727 .
   PubMed Web of Science ®Google Scholar
• Han , DS , Lee , HK and Cho , HJ. 1983 . Analgesic and anticonvulsionary effects of Ssanghwa-Tang . Kor J Pharmacog. , 14 : 60 – 63 .
   Google Scholar
• Han , YH and Shim , CK. 1989 . Effect of a blended Korean herbal remedy, Ssang Wha Tang, on the liver cytoplasmic protein binding of sulfobromophthalein in rats . Phytother Res. , 3 : 109 – 111 .
   Web of Science ®Google Scholar
• Heo J. 1994 Dongeuibogam Seoul Namsandang Press 670 675
   Google Scholar
• Hsu , H , Lacey , DL , Dunstan , CR , Solovyev , I , Colombero , A , Timms , E , Tan , HL , Elliott , G , Kelley , MJ Sarosi , I . 1999 . Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand . Proc Natl Acad Sci USA. , 96 : 3540 – 3545 .
   PubMed Web of Science ®Google Scholar
• Kalu , DN. 1991 . The ovariectomized rat model of postmenopausal bone loss . Bone Miner. , 15 : 175 – 191 .
   PubMedGoogle Scholar
• Kil , JS , Kim , MG , Choi , HM , Lim , JP , Boo , Y , Kim , EH , Kim , JB , Kim , HK and Leem , KH. 2008 . Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation . Phytother Res. , 22 : 472 – 476 .
   PubMed Web of Science ®Google Scholar
• Kim , IH and Hwang , KJ. 1981 . Studies on the anti-inflammtory activities of Ssangwha-tang . Natural Pro Sci. , 12 : 131 – 136 .
   Google Scholar
• Lee , H and Lim , HH. 2003 . Effects of Ssangwha-tang added to Cervi Cornu Parvum on bone density and bone biochemical marker in ovariectomized rats . J Ori R Med. , 13 : 45 – 67 .
   Google Scholar
• Lelovas , PP , Xanthos , TT , Thoma , SE , Lyritis , GP and Dontas , IA. 2008 . The laboratory rat as an animal model for osteoporosis research . Comp Med. , 58 : 424 – 430 .
   PubMed Web of Science ®Google Scholar
• Livak , KJ and Schmittgen , TD. 2001 . Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method . Methods. , 25 : 402 – 408 .
   PubMed Web of Science ®Google Scholar
• Lowe , C , Yoneda , T , Boyce , BF , Chen , H , Mundy , GR and Soriano , P. 1993 . Osteoporosis in Src-deficient mice is due to an autonomous defect of osteoclasts . Proc Natl Acad Sci USA. , 90 : 4485 – 4489 .
   PubMed Web of Science ®Google Scholar
• Oh , KO , Kim , SW , Kim , JY , Ko , SY , Kim , HM , Baek , JH , Ryoo , HM and Kim , JK. 2003 . Effect of Rehmannia glutinosa Libosch extracts on bone metabolism . Clin Chim Acta. , 334 : 185 – 195 .
   PubMed Web of Science ®Google Scholar
• Okamoto , F , Okabe , K and Kajiya , H. 2001 . Genistein, a soybean isoflavone, inhibits inward rectifier K(+) channels in rat osteoclasts . Jpn J Physiol. , 51 : 501 – 509 .
   PubMedGoogle Scholar
• Pang , M , Martinez , AF , Fernandez , I , Balkan , W and Troen , BR. 2007 . AP-1 stimulates the cathepsin K promoter in RAW 264.7 cells . Gene. , 15 : 151 – 158 .
   Google Scholar
• Putnam , SE , Scutt , AM , Bicknell , K , Priestley , CM and Williamson , EM. 2007 . Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health . Phytother Res. , 21 : 99 – 112 .
   PubMed Web of Science ®Google Scholar
• Qin , L , Han , T , Zhang , Q , Cao , D , Nian , H , Rahman , K and Zheng , H. 2008 . Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula . J Ethnopharmacol. , 118 : 271 – 279 .
   PubMed Web of Science ®Google Scholar
• Rodan , GA and Martin , TJ. 2000 . Therapeutic approaches to bone diseases . Science. , 289 : 1508 – 1514 .
   PubMed Web of Science ®Google Scholar
• Rozen , S and Skaletsky , HJ. 2000 . Primer3 on the WWW for general users and for biologist programmers . Methods Mol Biol. , 132 : 365 – 386 .
   PubMedGoogle Scholar
• Saftig , P , Hunziker , E , Everts , V , Jones , S , Boyde , A , Wehmeyer , O , Suter , A and von Figura , K. 2000 . Functions of cathepsin K in bone resorption. Lessons from cathepsin K deficient mice . Adv Exp Med Biol. , 477 : 293 – 303 .
   PubMed Web of Science ®Google Scholar
• Soriano , P , Montgomery , C , Geske , R and Bradley , A. 1991 . Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice . Cell , 64 : 693 – 702 .
   PubMed Web of Science ®Google Scholar
• Takayanagi , H , Kim , S , Koga , T , Nishina , H , Isshiki , M , Yoshida , H , Saiura , A , Isobe , M , Yokochi , T Inoue , J . 2002 . Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts . Dev Cell. , 3 : 889 – 901 .
   PubMed Web of Science ®Google Scholar
• Teitelbaum , SL. 2000 . Bone resorption by osteoclasts . Science. , 289 : 1504 – 1508 .
   PubMed Web of Science ®Google Scholar
• Won , JB , Ma , JY , Um , YR and Ma , CJ. 2010 . Simultaneous determination of five marker constituents in Ssanghwa tang by HPLC/DAD . Pharmacogn Mag , 6 : 111 – 115 .
   PubMed Web of Science ®Google Scholar
• Yen , PH , Kiem , PV , Nhiem , NX , Tung , NH , Quang , TH , Minh , CV , Kim , JW , Choi , EM and Kim , YH. 2007 . A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells . Arch Pharm Res. , 30 : 1179 – 1185 .
   PubMed Web of Science ®Google Scholar