Antiproliferative properties of Saussurea lappa Clarke root extract in SH-SY5Y neuroblastoma cells via intrinsic apoptotic pathway

References

• Adams JM, Cory S. 2007. Bcl-2-regulated apoptosis: mechanism and therapeutic potential. Curr Opin Immunol. 19:488–496. 10.1016/j.coi.2007.05.004
   PubMed Web of Science ®Google Scholar
• Bénard J, Raguénez G, Kauffmann A, Valent A, Ripoche H, Joulin V, Job B, Danglot G, Cantais S, Robert T, et al. 2008. MYCN-non-amplified metastatic neuroblastoma with good prognosis and spontaneous regression: a molecular portrait of stage 4S. Mol Oncol. 2:261–271.
   Google Scholar
• Bouchier-Hayes L, Lartigue L, Newmeyer DD. 2005. Mitochondria: pharmacological manipulation of cell death. J Clin Invest. 115:2640–2647. 10.1172/JCI26274DS1
   PubMed Web of Science ®Google Scholar
• Brady MJ, Bourbonais FJ, Saltiel AR. 1998. The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells. J Biol Chem. 273:14063–14066. 10.1074/jbc.273.23.14063
   PubMed Web of Science ®Google Scholar
• Breckenridge DG, Xue D. 2004. Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases. Curr Opin Cell Biol. 16:647–652. 10.1016/j.ceb.2004.09.009
   PubMed Web of Science ®Google Scholar
• Brodeur GM, Bagatell R. 2014. Mechanisms of neuroblastoma regression. Nat Rev Clin Oncol. [Internet]. [cited 2014 Oct 21];168. Available from: http://www.nature.com/nrclinonc/journal/vaop/ncurrent/abs/nrclinonc.2014.168.html
   PubMed Web of Science ®Google Scholar
• Cain K, Bratton SB, Cohen GM. 2002. The Apaf-1 apoptosome: a large caspase activating complex. Biochimie. 84:203–214.
   PubMed Web of Science ®Google Scholar
• Castel V, Grau E, Noguera R, Martínez F. 2007. Molecular biology of neuroblastoma. Clin Transl Oncol. 9:478–483. 10.1007/s12094-007-0091-7
   PubMed Web of Science ®Google Scholar
• Cecconi F, Gruss P. 2001. Apaf1 in developmental apoptosis and cancer: how many ways to die? Cell Mol Life Sci. 58:1688–1697. 10.1007/PL00000806
   PubMed Web of Science ®Google Scholar
• Chen HC, Chou CK, Lee SD, Wang JC, Yeh SF. 1995. Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells. Antiviral Res. 27:99–109. 10.1016/0166-3542(94)00083-K
   PubMed Web of Science ®Google Scholar
• Chen Q, Crosby M, Almasan A. 2003. Redox regulation of apoptosis before and after cytochrome c release. Korean J Biol Sci. 7:1–9. 10.1080/12265071.2003.9647675
   PubMedGoogle Scholar
• Chen PN, Hsieh YS, Chiou HL, Chu SC. 2005. Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways. Chem Biol Interact. 156:141–150. 10.1016/j.cbi.2005.08.005
   PubMed Web of Science ®Google Scholar
• Cho JY, Baik KU, Jung JH, Park MH. 2000. In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa. Eur. J. Pharmacol. 398:399–407.
   PubMed Web of Science ®Google Scholar
• Cory S, Adams JM. 2002. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer. 2:647–656. 10.1038/nrc883
   PubMed Web of Science ®Google Scholar
• Ekert PG, Silke J, Vaux DL. 1999. Caspase inhibitors. Cell Death Differ. 6:1081–1086. 10.1038/sj.cdd.4400594
   PubMed Web of Science ®Google Scholar
• García-Sáez AJ. 2012. The secrets of the Bcl-2 family. Cell Death Differ. 19:1733–1740.
   PubMed Web of Science ®Google Scholar
• Hong WK, Sporn MB. 1997. Recent advances in chemoprevention of cancer. Science. 278:1073–1077. 10.1126/science.278.5340.1073
   PubMed Web of Science ®Google Scholar
• Huang HP, Shih YW, Chang YC, Hung CN, Wang CJ. 2008. Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway. J Agric Food Chem. 56:9286–9293. 10.1021/jf8013102
   PubMed Web of Science ®Google Scholar
• Kelloff GJ, Crowell JA, Steele VE, Lubet RA, Malone WA, Boone CW, Kopelovich L, Hawk ET, Lieberman R, Lawrence JA, et al. 2000. Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. J Nutr. 130:467S–471S.
   PubMed Web of Science ®Google Scholar
• Ko SG, Kim HP, Jin DH, Bae HS, Kim SH, Park CH, Lee JW. 2005. Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells. Cancer Lett. 220:11–19. 10.1016/j.canlet.2004.06.026
   PubMed Web of Science ®Google Scholar
• Kuida, K. 2000. Caspase-9. Int J Biochem Cell Biol. 32:121–124. 10.1016/S1357-2725(99)00024-2
   PubMed Web of Science ®Google Scholar
• Leber B, Lin J, Andrews DW. 2010. Still embedded together binding to membranes regulates Bcl-2 protein interactions. Oncogene. 29:5221–5230. 10.1038/onc.2010.283
   PubMed Web of Science ®Google Scholar
• Maris JM, Hogarty MD, Bagatell R, Cohn SL. 2007. Neuroblastoma. Lancet. 369:2106–2120. 10.1016/S0140-6736(07)60983-0
   PubMed Web of Science ®Google Scholar
• Martinou JC, Youle RJ. 2011. Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics. Dev Cell. 21:92–101. 10.1016/j.devcel.2011.06.017
   PubMed Web of Science ®Google Scholar
• Maurer U, Charvet C, Wagman AS, Dejardin E, Green DR. 2006. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell. 21:749–760. 10.1016/j.molcel.2006.02.009
   PubMed Web of Science ®Google Scholar
• Ravindranath MH, Ramasamy V, Moon S, Ruiz C, Muthugounder S. 2009. Differential growth suppression of human melanoma cells by tea (Camellia sinensis) epicatechins (ECG, EGC and EGCG). Evid Based Complement Alternat Med. 6:523–530. 10.1158/1055-9965.EPI-03-0040
   PubMed Web of Science ®Google Scholar
• Shankar S, Ganapathy S, Hingorani SR, Srivastava RK. 2008. EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer. Front Biosci. 13:440–452. 10.2741/2691
   PubMed Web of Science ®Google Scholar
• Sporn MB, Suh N. 2000. Chemoprevention of cancer. Carcinogenesis. 21:525–530. 10.1093/carcin/21.3.525
   PubMed Web of Science ®Google Scholar
• Strasser A. 2005. The role of BH3-only proteins in the immune system. Nat Rev Immunol. 5:189–200. 10.1038/nri1568
   PubMed Web of Science ®Google Scholar
• Strasser A, Cory S, Adams JM. 2011. Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases. EMBO J. 30:3667–3683. 10.1038/emboj.2011.307
   PubMed Web of Science ®Google Scholar
• Sun CM, Syu WJ, Don MJ, Lu JJ, Lee GH. 2003. Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. J Nat Prod. 66:1175–1180. 10.1021/np030147e
   PubMed Web of Science ®Google Scholar
• Takahashi-Yanaga F, Sasaguri T. 2009. Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs. J Pharmacol Sci. 109:179–183. 10.1254/jphs.08R28FM
   PubMed Web of Science ®Google Scholar
• Thornberry NA, Lazebnik Y. 1998. Caspases: enemies within. Science. 281:1312–1316. 10.1126/science.281.5381.1312
   PubMed Web of Science ®Google Scholar
• van Weeren PC, de Bruyn KM, de Vries-Smits AM, van Lint J, Burgering BM. 1998. Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation characterization of dominant-negative mutant of PKB. J Biol Chem. 273:13150–13156. 10.1074/jbc.273.21.13150
   PubMed Web of Science ®Google Scholar
• Vieira JR, de Souza IA, do Nascimento SC, Leite SP. 2007. Indigofera suffruticosa: an alternative anticancer therapy. Evid Based Complement Alternat Med. 4:355–359. 10.1093/ecam/nel102
   PubMed Web of Science ®Google Scholar
• Wang X. 2001. The expanding role of mitochondria in apoptosis. Genes Dev. 15:2922–2933.
   PubMed Web of Science ®Google Scholar
• Yoshikawa M, Hatakeyama S, Inoue Y, Yamahara J. 1993. Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae radix. Chem Pharm Bull (Tokyo). 41:214–216. 10.1248/cpb.41.214
   PubMed Web of Science ®Google Scholar
• Youle RJ, Strasser A. 2008. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol. 9:47–59. 10.1038/nrm2308
   PubMed Web of Science ®Google Scholar
• Zahara K, Tabassum S, Sabir S, Arshad M, Qureshi R, Amjad MS, Chaudhari SK. 2014. A review of therapeutic potential of Saussurea lappa – an endangered plant from Himalaya. Asian Pac J Trop Med. S1:S60–S69. 10.1016/S1995-7645(14)60204-2
   Google Scholar