Advanced search
Publication Cover
Libyan Journal of Medicine Volume 16, 2021 - Issue 1
Submit an article Journal homepage
2,265
Views
2
CrossRef citations to date
0
Altmetric
Original Article

HER2 overexpression is a putative diagnostic and prognostic biomarker for late-stage colorectal cancer in North African patients

Eman A. Abdul Razzaqa Clinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates;b Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab EmiratesView further author information
,
Thenmozhi Venkatachalamb Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab EmiratesView further author information
,
Khuloud Bajbouja Clinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab EmiratesView further author information
,
Mohamed Rahmania Clinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates;b Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab EmiratesORCID Iconhttps://orcid.org/0000-0002-3992-8039View further author information
ORCID Icon,
Amena Mahdamib Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab EmiratesORCID Iconhttps://orcid.org/0000-0002-3226-6933View further author information
ORCID Icon,
Surendra Rawatb Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab EmiratesORCID Iconhttps://orcid.org/0000-0002-7414-5865View further author information
ORCID Icon,
Naziha Mansuric Department of Pathology, University of Turku, FinlandORCID Iconhttps://orcid.org/0000-0002-1606-8478View further author information
ORCID Icon,
Hussein Alhashemid Department of surgery NCI, Sabratha, LibyaView further author information
,
Rifat Akram Hamoudia Clinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates;b Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates;e Division of Surgery and Interventional Science, University College London, London, United KingdomORCID Iconhttps://orcid.org/0000-0002-1402-0868View further author information
ORCID Icon &
Riyad Bendardafa Clinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates;f Oncology Unit, University Hospital Sharjah, Sharjah, United Arab EmiratesCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5158-4590View further author information
ORCID Icon show all
Article: 1955462 | Received 24 Mar 2021, Accepted 09 Jul 2021, Published online: 28 Jul 2021

References

  • Siegel RL, Miller KD, Goding Sauer A, et al. Colorectal cancer statistics, 2020. CA Cancer J Clin. 2020;70(3):145–7. Epub 2020/03/07.
  • Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. Epub 2018/09/13.
  • El Mistiri M, Salati M, Marcheselli L, et al. Cancer incidence, mortality, and survival in eastern libya updated report from the benghazi cancer registry. Ann Epidemiol. 2015;25(8):564–568. Epub 2015/04/29.
  • Bodalal Z, Bendardaf R. Colorectal carcinoma in a southern mediterranean country: The libyan scenario. World J Gastrointest Oncol. 2014;6(4):98–103. Epub 2014/04/16.
  • Bodalal Z, Azzuz R, Bendardaf R. Cancers in eastern libya: first results from benghazi medical center. World J Gastroenterol. 2014;20(20):6293–6301. Epub 2014/05/31.
  • Oh DY, Bang YJ. HER2-targeted therapies - a role beyond breast cancer. Nat Rev Clin Oncol. 2020;17(1):33–48. Epub 2019/09/25.
  • Koeppen HK, Wright BD, Burt AD, et al. Overexpression of HER2/neu in solid tumours: an immunohistochemical survey. Histopathology. 2001;38(2):96–104. Epub 2001/02/24.
  • Kruszewski WJ, Rzepko R, Ciesielski M, et al. Expression of HER2 in colorectal cancer does not correlate with prognosis. Dis Markers. 2010;29(5):207–212. Epub 2011/01/06.
  • Ross JS, Fakih M, Ali SM, et al. Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3. Cancer. 2018;124(7):1358–1373. Epub 2018/01/18.
  • Wang XY, Zheng ZX, Sun Y, et al. Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas. World J Gastrointest Oncol. 2019;11(4):335–347. Epub 2019/05/02.
  • Li G, Zheng J, Xu B, et al. Simvastatin inhibits tumor angiogenesis in HER2-overexpressing human colorectal cancer. Biomed Pharmacother. 2017;85:418–424. [ Epub 2016/11/27].
  • Sartore-Bianchi A, Amatu A, Porcu L, et al. HER2 positivity predicts unresponsiveness to EGFR-targeted treatment in metastatic colorectal cancer. Oncologist. 2019;24(10):1395–1402. Epub 2019/04/07.
  • Buhmeida A, Assidi M, Al-Maghrabi J, et al. Membranous or cytoplasmic HER2 expression in colorectal carcinoma: evaluation of prognostic value using both IHC & BDISH. Cancer Invest. 2018;36(2):129–140. Epub 2018/03/06.
  • Pyo JS, Kang G, Park K. Clinicopathological significance and diagnostic accuracy of HER2 immunohistochemistry in colorectal cancer: a meta-analysis. Int J Biol Markers. 2016;31(4):e389–e94. Epub 2016/10/30.
  • Owen DR, Wong HL, Bonakdar M, et al. Molecular characterization of ERBB2 amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases. Cold Spring Harb Mol Case Stud. 2018;4(2):2. Epub 2018/02/14.
  • Pye H, Butt MA, Funnell L, et al. Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression. Oncotarget. 2018;9(33):22945–22959. Epub 2018/05/26.
  • Tadmouri GO, Sastry KS, Chouchane L. Arab gene geography: from population diversities to personalized medical genomics. Glob Cardiol Sci Pract. 2014;2014(4): 394–408. Epub 2014/01/01
  • Dowsett M, Hanby AM, Laing R, et al. HER2 testing in the UK: consensus from a national consultation. J Clin Pathol. 2007;60(6):685–689. Epub 2007/02/27.
  • Valtorta E, Martino C, Sartore-Bianchi A, et al. Assessment of a HER2 scoring system for colorectal cancer: results from a validation study. Mod Pathol. 2015;28(11):1481–1491. Epub 2015/10/10.
  • Liu F, Ren C, Jin Y, et al. Assessment of two different HER2 scoring systems and clinical relevance for colorectal cancer. Virchows Arch. 2020;476(3):391–398. Epub 2019/11/14.
  • Khiari H, Ben Ayoub HW, Ben Khadhra H, et al. Colorectal cancer incidence trend and projections in tunisia (1994–2024). Asian Pac J Cancer Prev. 2017;18(10): 2733–2739. Epub 2017/10/27.
  • Lo AC, Soliman AS, Khaled HM, et al. Lifestyle, occupational, and reproductive factors and risk of colorectal cancer. Dis Colon Rectum. 2010;53(5):830–837. Epub 2010/04/15.
  • Wang XY, Zheng ZX, Sun Y, et al. Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas. World J Gastrointest Oncol. 2019;11(4):335–347.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.