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Journal of Plastic Surgery and Hand Surgery Volume 51, 2017 - Issue 1: The Scandcleft randomised controlled trials
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Original Article

Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management

Gunvor SembDivision of Dentistry, University of Manchester, Manchester, UK; ;Department of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; ;Department of Speech and Language Disorders, Statped sørøst, Oslo, Norway; Correspondence[email protected] [email protected]
View further author information
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Hans EnemarkCleft Palate Center, Aarhus, Denmark; View further author information
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Hans FriedeDepartment of Orthodontics, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
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Gunnar PaulinDepartment of Dentofacial Orthopedics, University Hospital, Linköping, Sweden; View further author information
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Jan LiljaDepartment of Plastic Surgery, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
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Jorma RautioCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Mikael AndersenCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Frank ÅbyholmDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
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Anette LohmanderDivision of Speech and Language Pathology, Karolinska Institute, and Karolinska University Hospital, Stockholm, Sweden; View further author information
,
William ShawDivision of Dentistry, University of Manchester, Manchester, UK; View further author information
,
Kirsten MølstedCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Arja HeliövaaraCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Stig BolundCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Jyri HukkiCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Hallvard VindenesCentre for Cleft Lip and Palate, Bergen University Hospital Haukeland, Bergen, Norway; View further author information
,
Peter DavenportGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
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Kjartan ArctanderDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
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Ola LarsonStockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden; View further author information
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Anders BerggrenDepartment of Plastic Surgery, University Hospital, Linköping, Sweden; View further author information
,
David WhitbyGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
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Alan LeonardThe Royal Hospital for Sick Children, Belfast, N. Ireland; View further author information
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Erik NeoviusStockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden; View further author information
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Anna ElanderDepartment of Plastic Surgery, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
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Elisabeth WilladsenDepartment of Nordic Studies and Linguistics, University of Copenhagen, Denmark; View further author information
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R. Patricia BannisterGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
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Eileen BradburyPrivate Practitioner, Manchester, UK; View further author information
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Gunilla HenningssonStockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden; View further author information
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Christina PerssonInstitute of Neuroscience and Physiology, Speech and Language Pathology Unit, Sahlgrenska Academy, University of Gothenburg, Sweden; ;Division for Speech and Language Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden; View further author information
,
Philip EyresDivision of Dentistry, University of Manchester, Manchester, UK; View further author information
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Berit EmborgCleft Palate Center, Aarhus, Denmark; View further author information
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Mia Kisling-MøllerDivision of Dentistry, University of Manchester, Manchester, UK; View further author information
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Annelise KüselerDivision of Dentistry, University of Manchester, Manchester, UK; View further author information
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Birthe Granhof BlackDivision of Dentistry, University of Manchester, Manchester, UK; View further author information
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Antje SchöpsCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Anja BauCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Maria BoersCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Helene Søgaard AndersenCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Karin JeppesenCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Dorte MarxenCopenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark; View further author information
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Marjukka PaasoCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Elina HölttäCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Suvi AlaluusuaCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Leena TurunenCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Kirsti HumerintaCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Ulla Elfving-LittleCleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland; View further author information
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Inger Beate TørdalDepartment of Speech and Language Disorders, Statped sørøst, Oslo, Norway; View further author information
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Lillian KjøllDepartment of Speech and Language Disorders, Statped sørøst, Oslo, Norway; View further author information
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Ragnhild AuknerDepartment of Speech and Language Disorders, Statped sørøst, Oslo, Norway; View further author information
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Øydis HideDepartment of Speech and Language Disorders, Statped sørøst, Oslo, Norway; View further author information
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Kristin Billaud FeragenDepartment of Speech and Language Disorders, Statped sørøst, Oslo, Norway; View further author information
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Elisabeth RønningDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
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Pål SkaareDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
,
Eli BrinckDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
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Ann-Magritt SemmingsenDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
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Nina LindbergDepartment of Plastic and Reconstructive Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; View further author information
,
Melanie BowdenGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
,
Julie DaviesGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
,
Jeanette MooneyGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
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Haydn BellardieGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
,
Nina SchofieldGreater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens’ Hospital, Manchester, UK; View further author information
,
Jill NybergStockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden; View further author information
,
Maria LundbergStockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden; View further author information
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Agneta Linder-Aronson KarstenStockholm Craniofacial Team, Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden; View further author information
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Margareta LarsonEastman Institute, Stockholms Läns Landsting, Stockholm, Sweden; View further author information
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Anders HolmefjordStatped vest, Bergen, Norway; View further author information
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Sigvor ReisæterStatped vest, Bergen, Norway; View further author information
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Nina-Helen PedersenStatped vest, Bergen, Norway; View further author information
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Therese RasmussenStatped vest, Bergen, Norway; View further author information
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Rolf TindlundDental School, University of Bergen, Bergen, Norway; View further author information
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Paul SæleOral Health Center of Expertise/Western Norway, Bergen, Norway; View further author information
,
Reidunn BlomhoffCentre for Cleft Lip and Palate, Bergen University Hospital Haukeland, Bergen, Norway; View further author information
,
Gry JacobsenCentre for Cleft Lip and Palate, Bergen University Hospital Haukeland, Bergen, Norway; View further author information
,
Christina HavstamDivision for Speech and Language Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden; View further author information
,
Sara RizellDepartment of Orthodontics, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
,
Lars EnocsonDepartment of Orthodontics, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
,
Catharina HagbergDepartment of Orthodontics, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
,
Midia Najar ChalienDepartment of Orthodontics, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
,
Anna PaganiniDepartment of Plastic Surgery, Sahlgrenska Academy, University of Gothenburg, Sweden; View further author information
,
Inger LundeborgDivision of Speech and Language Pathology, Linköping University, Linköping, SwedenView further author information
,
Agneta MarcussonDepartment of Dentofacial Orthopedics, University Hospital, Linköping, Sweden; View further author information
,
Anna-Britta MjönesDepartment of Plastic Surgery, University Hospital, Linköping, Sweden; View further author information
,
Annica GustavssonDepartment of Dentofacial Orthopedics, University Hospital, Linköping, Sweden; View further author information
,
Christine HaydenThe Royal Hospital for Sick Children, Belfast, N. Ireland; View further author information
,
Eilish McAleerThe Royal Hospital for Sick Children, Belfast, N. Ireland; View further author information
,
Emma SlevanThe Royal Hospital for Sick Children, Belfast, N. Ireland; View further author information
,
Terry GreggThe Royal Hospital for Sick Children, Belfast, N. Ireland; View further author information
&
Helen WorthingtonDivision of Dentistry, University of Manchester, Manchester, UK; View further author information
 show all
Pages 2-13 | Received 21 Mar 2016, Accepted 15 Nov 2016, Published online: 20 Feb 2017

References

  • Spriestersbach DC, Dickson DR, Fraser FC, et al. Clinical research in cleft lip and cleft palate: the state of the art. Cleft Palate J 1973;10:113–65.
  • Shaw WC, Semb G, Nelson P, et al. The Eurocleft project 1996-2000: overview. J Craniomaxillofac Surg 2001;29:131–40.
  • Friede H, Enemark H, Semb G, et al. Craniofacial and occlusal characteristics in unilateral cleft lip and palate patients from four Scandinavian centres. Scand J Plast Reconstr Surg Hand Surg 1991;25:269–76.
  • Enemark H, Friede H, Paulin G, et al. Lip and nose morphology in patients with unilateral cleft lip and palate from four Scandinavian centres. Scand J Plast Reconstr Surg Hand Surg 1993;27:41–7.
  • Rautio J, Andersen M, Bolund S, et al. Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 2. Surgical results. J Plast Surg Hand Surg 2017;51:13–19.
  • Lohmander A, Willadsen E, Persson C, et al. Methodology for speech assessment in the Scandcleft project – an international randomized clinical trial on palatal surgery: experiences from a pilot study. Cleft Palate Craniofac J 2009;46:347–62.
  • Lohmander A, Persson C, Willadsen E, et al. Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 4. Speech outcomes in 5-year-olds - velopharyngeal competency and hypernasality. J Plast Surg Hand Surg 2017;51:26–36.
  • Willadsen E, Lohmander A, Persson C, et al. Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 5. Speech outcomes in 5-year-olds - consonant production. J Plast Surg Hand Surg 2017;51:37–50.
  • Marsh JL, Grames LM, Hottman B. Intravelar veloplasty: a prospective study. Cleft Palate J 1989;26:46–50.
  • Shaw WC, Asher-McDade C, Brattström V, et al. The RPS: a six centre international study of treatment outcome in patients with clefts of the lip and palate: Part 5. General discussion and conclusions. Cleft Palate Craniofac J 1992;29:413–18.
  • Freitas JA1, das Neves LT, de Almeida AL, et al. Rehabilitative treatment of cleft lip and palate: experience of the Hospital for Rehabilitation of Craniofacial Anomalies/USP (HRAC/USP)–Part 1: overall aspects. J Appl Oral Sci 2012;20:9–15.
  • TOPS trial website June 10, 2015: www.tops-trial.org.uk

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