FGF-2-containing dalteparin/protamine nanoparticles (FGF-2&D/P NPs) ameliorate UV-induced skin photoaging in hairless mice

References

• Ichihashi M, Ando H, Yoshida M, et al. Photoaging of the skin. Anti-Aging Med. 2009;6:46–59.
   Google Scholar
• Zhou BR, Yin HB, Xu Y, et al. Baicalin protects human skin fibroblasts from ultraviolet A radiation-induced oxidative damage and apoptosis. Free Radic Res. 2012;46:1458–1471.
   PubMed Web of Science ®Google Scholar
• Kinoda J, Ishihara M, Nakamura S, et al. Protective effect of FGF-2 and low-molecular-weight heparin/protamine nanoparticles on radiation-induced healing-impaired wound repair in rats. J Radiat Res. 2018;59:27–34.
   PubMed Web of Science ®Google Scholar
• Liebel F, Kaur S, Ruvolo E, et al. Irradiation of skin with visible light induces reactive oxygen species and matrix-degrading enzymes. J Invest Dermatol. 2012;132:1901–1907.
   PubMed Web of Science ®Google Scholar
• Quan T, Qin Z, Xu Y, et al. Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts. J Invest Dermatol. 2010;130:1697–1706.
   PubMed Web of Science ®Google Scholar
• Ichihashi M, Ando H. Themaximal cumulative solarUVB dose allowed to maintain healthy and young skin and prevent premature photoaging. Exp Dermatol. 2014;23:43–46.
   PubMed Web of Science ®Google Scholar
• Poljsak B, Dahmane R. Free radicals and extrinsic skin aging. Dermatol Res Pract. 2012;2012:135206.
   PubMedGoogle Scholar
• Bens G. Sunscreens. Adv Exp Med Biol. 2014;810:429–463.
   PubMedGoogle Scholar
• Ishihara M, Kishimoto S, Takikawa M, et al. Biomedical application of low molecular weight heparin/protamine nano/micro particles as cell- and growth factor-carriers and coating matrix. Ijms. 2015;16:11785–11803.
   Google Scholar
• Motomura K, Hagiwara A, Komi-Kuramochi A, et al. An FGF1:FGF2 chimeric growth factor exhibits universal FGF receptor specificity, enhanced stability and augmented activity useful for epithelial proliferation and radioprotection. Biochim Biophys Acta. 2008;1780:1432–1440.
   PubMed Web of Science ®Google Scholar
• Watanabe S, Fujita M, Ishihara M, et al. Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats. J Radiat Res. 2014;55:1107–1113.
   PubMed Web of Science ®Google Scholar
• Ding I, Huang K, Wang X, et al. Radioprotection of hematopoietic tissue by fibroblast growth factors in fractionated radiation experiments. Acta Oncol. 1997;36:337–340.
   PubMed Web of Science ®Google Scholar
• Cotrim AP, Sowers A, Mitchell JB, et al. Prevention of irradiation-induced salivary hypofunction by microvessel protection in mouse salivary glands. Mol Ther. 2007;15:2101–2106.
   PubMed Web of Science ®Google Scholar
• Liu Z, Liu H, Jiang J, et al. PDGF-BB and bFGF ameliorate radiation-induced intestinal progenitor/stem cell apoptosis via Akt/p53 signaling in mice. Am J Physiol Gastrointest Liver Physiol. 2014;307:G1033–G1043.
   PubMed Web of Science ®Google Scholar
• Pena LA, Fuks Z, Kolesnick RN. Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency. Cancer Res. 2000;60:321–327.
   PubMed Web of Science ®Google Scholar
• Ishihara M. Structural requirements in heparin for binding and activation of FGF-1 and FGF-4 are different from that for FGF-2. Glycobiology. 1994;4:817–824.
   PubMed Web of Science ®Google Scholar
• Nakamura S, Kanatani Y, Kishimoto S, et al. Controlled release of FGF-2 using fragmin/protamine microparticles and effect on neovascularization. J Biomed Mater Res A. 2009;91:814–823.
   PubMed Web of Science ®Google Scholar
• Mori Y, Nakamura S, Kishimoto S, et al. Preparation and characterization of low-molecular-weight heparin/protamine nanoparticles (LMW-H/P NPs) as FGF-2 carrier. Int J Nanomedicine. 2010;5:147–155.
   PubMed Web of Science ®Google Scholar
• Kishimoto S, Ishihara M, Nakamura S, et al. Fragmin/protamine microparticles to adsorb and protect HGF and to function as local HGF carriers in vivo. Acta Biomater. 2013;9:4763–4770.
   PubMed Web of Science ®Google Scholar
• Takikawa M, Nakamura S, Nakamura S, et al. Enhancement of vascularization and granulation tissue formation by growth factors in human platelet-rich plasma containing fragmin/protamine microparticles. J Biomed Mater Res. 2011;97B:373–380.
   Web of Science ®Google Scholar
• Takikawa M, Ishihara M, Takabayashi Y, et al. Enhanced healing of mitomycin C-treated healing-impaired wounds in rats with PRP-containing fragmin/protamine microparticles (PRP&F/P MPs). J Plast Surg Hand Surg. 2015;49:268–274.
   PubMed Web of Science ®Google Scholar
• Nemeno JGE, Lee S, Yang W, et al. Applications and implications of heparin and protamine in tissue engineering and regenerative medicine. Biomed Res Int. 2014;2014:936196.
   PubMedGoogle Scholar
• Kim HK. Garlic supplementation ameliorates UV-induced photoaging in hairless mice by regenerating antioxidation activity and MMPs expression. Molecules. 2016;21:70.
   PubMedGoogle Scholar
• Marie M, Hafner S, Moratille S, et al. FGF2 mediates DNA repair in epidermoid carcinoma cells exposed to ionizing radiation. Int J Radiat Biol. 2012;88:688–693.
   PubMed Web of Science ®Google Scholar
• Fuks Z, Persaud RS, Alfieri A, et al. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res. 1994;54:2582–2590.
   PubMed Web of Science ®Google Scholar
• Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med. 2000;6:389–395.
   PubMed Web of Science ®Google Scholar
• Paris F, Fuks Z, Kang A, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science. 2001;293:293–297.
   PubMed Web of Science ®Google Scholar
• Garcia-Barros M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science. 2003;300:1155–1159.
   PubMed Web of Science ®Google Scholar
• Nagai N, Iwamae A, Tanimoto S, et al. Pharmacokinetics and anti-inflammatory effect of novel gel system containing ketoprofen solid nanoparticles. Biol Pharm Bull. 2015;38:1918–1924.
   PubMed Web of Science ®Google Scholar
• Osmond-McLeod MJ, Oytam Y, Kirby JK, et al. Dermal absorption and short-term biological impact in hairless mice from sunscreens containing zinc oxide nano- or larger particles. Nanotoxicology. 2014;8:72–84.
   PubMed Web of Science ®Google Scholar
• Takikawa M, Nakamura S-I, Nakamura S, et al. Enhanced effect of platelet-rich plasma containing a new carrier on hair growth. Dermatol Surg. 2011;37:1721–1729.
   PubMed Web of Science ®Google Scholar
• Takabayashi Y, Mambu M, Ishihara M, et al. Enhancement effect of fibroblast growth factor-2-containing delteparin/protamine nanoparticles on hair growth. Cli Cosmt Invest Dermatol. 2016;9:127–134.
   PubMed Web of Science ®Google Scholar