Escherichia coli O157:H7 As An Emerging Foodborne Pathogen: A Literature Review

REFERENCES

• Burnet, F. M., Natural history of infectious disease. Cambridge University Press, London, 1962.
   Google Scholar
• Fauci, A. S., New and Reemerging diseases: the importance of biomedical research. Emerg. Infect. Dis., 4, 374–378, 1998.
   PubMed Web of Science ®Google Scholar
• Lederberg, J., Emerging infections: an evolutionary perspective. Emerg. Infect. Dis., 4, 366–371, 1998.
   PubMed Web of Science ®Google Scholar
• Shalala, D. E., Collaboration in the fight against infection diseases. Emerg. Infect. Dis., 4, 354–357, 1998.
   PubMed Web of Science ®Google Scholar
• Levine, B. R., The evolution and maintenance of virulence in microparasites. Emerg. Infect. Dis., 2, 93–102, 1996.
   PubMed Web of Science ®Google Scholar
• Morse, S. S., Factors in the emergence of infectious diseases. Emerg. Infect. Dis., 1, 7–15, 1995.
   PubMed Web of Science ®Google Scholar
• Ochman, H. and Groisman, E. A., The origin and evolution of species differences in Escherichia coli and Salmonella typhimurium. In: Molecular Ecology and Evolution: Approaches and Applications, Schierwater, B., Streit, B., Wagner, G. P., and DeSalle, R., Eds., Birkhauser Verlag, Boston, 1994, 479–493.
   Google Scholar
• Selander, R. K., Li, J., and Nelson, K., Evolutionary genetics of Salmonella enterica. In: Escherichia coli and Salmonella: cellular and molecular biology, Neidhart, F. C., Ed., ASM Press, Washington, D.C., 1996, 2694.
   Google Scholar
• Falkow, S., The evolution of pathogenicity in Escherichia, Shigella, and Salmonella. In: Escherichia coli and Salmonella: cellular and molecular biology, Neidhart, F. C., Ed., ASM Press, Washington, D.C., 1996, 2723–2725
   Google Scholar
• Wells, C. L., Maddaus, M. A., and Simmons, R. L., Proposed mechanisms for the translocation of intestinal bacteria. Rev. Infect. Dis., 10, 958–979, 1988.
   PubMedGoogle Scholar
• Finlay, B. B. and Falkow, S., Common themes in microbial pathogenicity. Microbiol. Rev., 53, 210–230, 1989.
   PubMedGoogle Scholar
• Yamamoto, T., Honda, T., Miwatani, T., and Yokota, T., A virulence plasmid in Escherichia coli enterotoxigenic for humans: intergenetic transfer and expression. J. Infect. Dis., 150, 688–698, 1984.
   PubMed Web of Science ®Google Scholar
• Lai, V., Wang, L., and Reeves, P. R., Escherichia coli clone Sonnei (Shigella sonnei) had a chromosomal O-antigen gene cluster prior to gaining its current plasmid-borne O-antigen genes. J. Bacteriol., 180, 2983–2986, 1998.
   Google Scholar
• Knapp, S., Hacker, J., Jarchau, T., and Goebel, W., Large, unstable inserts in the chromosome affect virulence properties of uropathogenic Escherichia coli O6 strain 536. J. Bacteriol., 168, 22–30, 1986.
   PubMed Web of Science ®Google Scholar
• Mecsas, J. and Strauss, E. J., Molecular mechanisms of bacterial virulence: type III secretion and pathogenicity Islands. Emerg. Infect. Dis., 2, 271–288, 1996.
   Web of Science ®Google Scholar
• McDaniel, T. K., Jarvis, K. G., Donnenberg, M. S., and Kaper, J. B., A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc. Natl. Acad. Sci. U.S.A., 92, 1664–1668, 1995.
   PubMed Web of Science ®Google Scholar
• Hacker, J., Blum-Oehler, G., Muhldorfer, I, and Tschape, H., Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol. Microbiol., 6, 1089–1097, 1997.
   Google Scholar
• McDaniel, T. K. and Kaper, J. B., A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12. Mol. Microbiol, 23, 399–407, 1997.
   PubMed Web of Science ®Google Scholar
• Feng, P., Escherichia coli serotype O157:H7: novel vehicles of infection and emergence of phenotypic variants. Emerg. Infect. Dis., 1, 47–49, 1995.
   PubMedGoogle Scholar
• Whittman, T. S., Evolution of Escherichia coli O157:H7 and other shiga toxin-producing E. coli strains. In: Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains, Kaper, J. B. and O’Brien, A. D., Eds., ASM Press, Washington, D.C., 1998, 195–209.
   Google Scholar
• O’Brien, A. D. and Holmes, R. K., Shiga and Shiga-like toxins. Microbiol. Rev., 51, 206–220, 1987.
   PubMedGoogle Scholar
• Bilge, S. S., Vary, J. J. C., Dowell, S. F., and Tarr, P. I., Role of the Escherichia coli O157:H7 O side chain in adherence and analysis of an rfb locus. Infect. Immun., 64, 4795–4801, 1996.
   PubMed Web of Science ®Google Scholar
• Strockbine, N. A., Marques, L. R. M., Newland, J. W., Smith, H. W., Holmes, R. K., and O’Brien, A. D., Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities. Infect. Immun., 53, 135–140, 1986.
   PubMed Web of Science ®Google Scholar
• Shiga, K., Ueber den Dysenterie-bacillus (Bacillus dysenteriae). Zentralbl. Bakteriol. Orig, 24, 913–918, 1898.
   Google Scholar
• Gasser, G., Gautier, C., Steck, A., Siebemann, R. E., and Oechslin, R., Hamolytisch-uremische Syndrome. Bilaterale Nierenindennekrosen bei akuten erworbenen hamolyticschem Anamein. Schweiz. Med. Woschenshr., 85, 905–909, 1995.
   Google Scholar
• Keusch, G. T., Grady, G. F., Mata, L. J., and McIver, J., The pathogenesis of Shigella diarrhea. I. Enterotoxin production by Shigella dysenteriae 1. J. Clin. Invest., 51, 1212–1218, 1972.
   PubMed Web of Science ®Google Scholar
• Konowalchuk, S., Speir, J. I., and Stavric, S., Vero response to a cytotoxin of Escherichia coli. Infect. Immun., 18, 775–779, 1977.
   Google Scholar
• Riley, L. W., Remis, R. S., Helgerson, S. D., McGee, H. B., Wells, J. G., Davis, B. R., Hebert, R. J., Olcott, E. S., Johnson, L. M., Hargrett, N. T., Blake, P. A., and Cohen, M. L., Hemorrhagic colitis associated with a rare Escherichia coli serotype. N. Engl. J. Med., 30, 681–685, 1983.
   Google Scholar
• O’Brien, A. D. and LaVeck, G. D., Purification and characterization of a Shigella dysentriae 1-like toxin produced by Escherichia coli. Infect. Immun., 40, 675–683, 1983.
   Google Scholar
• Karmali, M. A., Petric, M., Lim, C., Fleming, P. C., Arbus, G. S., and Lior, H., The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli. J. Infect. Dis, 151, 775–782, 1985.
   Google Scholar
• Scotland, S. M., Smith, H. R., Wilshaw, G. A., and Rowe, B., Vero cytotoxin production in strain of Escherichia coli is determined by genes carried on bacteriophage. Lancet, 2, 216, 1983.
   PubMed Web of Science ®Google Scholar
• Lingwood, C. A., Law, H., Richardson, S. E., Petric, M., Brunton, J. L., De Grandis, S., and Karmali, M. A., Glycolipid binding of natural and recombinant Escherichia coli produced verotoxin in vitro. J. Biol. Chem, 262, 1779–1785, 1987.
   Google Scholar
• Wadell, T., Head, S., Petric, M., Cohen, A., and Lingwood, C. A., Globotriosyl ceramide is specifically recognized by the Escherichia coli verocytotoxin 2. Biochem. Biophys. Res. Commun, 152, 674–679, 1987.
   Web of Science ®Google Scholar
• Ogasawara, T., Ito, K., Igarashi, K., Yutsudo, T., and Takeda, Y., Inhibition of elongation factor 1-dependent aminoacyl-tRNA binding to ribosomes by Shiga-like toxin I (VT I) from Escherichia coli O157:H7 and by Shiga toxin. FEMS Microbiol. Lett., 44, 91–94, 1987.
   Web of Science ®Google Scholar
• Tzipori, S., Wachsmuth, I. K., Champman, C., Birden, R., Brittingham, J., Jackson, C., and Hogg, J., The pathogenesis of hemorrhagic colitis caused by Escherichia coli O157:H7 in gnotobiotic piglets. J. Infect. Dis, 154, 712–716, 1986.
   PubMed Web of Science ®Google Scholar
• Levine, M. M., Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent. J. Infect. Dis., 155, 377–389, 1987.
   PubMed Web of Science ®Google Scholar
• Tzipori, S., Gunzer, F., Donnenberg. M. S., de Montigny, L., Kaper, J. B., and Donohue-Rolfe, A., The role of the eaeA gene in diarrhea and neurological complication in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection. Infect. Immun., 63, 3621–3627, 1995.
   PubMed Web of Science ®Google Scholar
• Kenny, B. and Finlay, B. B., Protein secretion by enteropathogenic Escherichia coli is essential for transducing signals to epithelial cells. Proc. Natl. Acad. Sci. U.S.A., 92, 7991–7995, 1995.
   PubMed Web of Science ®Google Scholar
• Calderwood, S. B., Acheson, D. W. K., Keusch, G. T., Barrett, T. J., Griffin, P. M., Strockbine, N. A., Swaminathan, B., Kaper, J. B., Levine, M. M., Kaplan, B. S, Karch, H., O’Brien, A. D., Obrig, T. G., Takeda, Y., Tarr, P. I., and Wachsmuth, I. K., Proposed new nomenclature of SLT (VT) family. ASM News, 62, 118–119, 1996.
   Google Scholar
• Caprioli, A., Tozzi, A. E., Rizzoni, G., and Karch, H., Non-O157 Shiga toxin-producing Escherichia coli infections in Europe. J. Food Protect., 3, 578–579, 1997.
   Google Scholar
• Simmons, N. A., Global perspectives on Escherichia coli O157:H7 and other verocytotoxic E. coli spp.: UK Views. J. Food Prot., 60, 1463–1465, 1997.
   Web of Science ®Google Scholar
• Douglas, A. S. and Kurien, A., Seasonality and other epidemiological features of haemolytic uraemic syndrome and Escherichia coli O157 isolates in Scotland. Scott. Med. J, 42, 166–71, 1997.
   PubMed Web of Science ®Google Scholar
• Cowden, J. M. and Christie, P., Scottish outbreak of Escherichia coli O157. Health Bull., 55, 9–10, 1997.
   Google Scholar
• Anon., E. coli O157: lessons of the Scottish outbreak. Vet. Rec., 140, 382, 1997.
   PubMed Web of Science ®Google Scholar
• Caprioli, A. and Tozzi, A. E., Epidemiology of Shiga toxin-producing Escherichia coli infections in continental Europe. In: Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains. Kaper, J. B. and O’Brien, A. D., Eds., ASM Press, Washington, D.C., 1998, 38–48.
   Google Scholar
• Wieler, L. H., Schwanitz, A., Vieler, E., Busse, B., Steinruck, H., Kaper, J. B., and Baljer, G., Virulence properties of Shiga toxin-producing Escherichia coli (STEC) strains of serogroup O118, a major group of STEC pathogens in calves. J. Clin. Microbiol., 36, 1604–1607, 1998.
   PubMed Web of Science ®Google Scholar
• Huber, H. C., Kugler, R., and Liebl, B., Infections with enterohemorrhagic Escherichia coli (EHEC)—results of an epidemiologic survey in Bavaria for the April 1996 to May 1997 time frame. Gesundheitswesen, 60, 159–65, 1998.
   PubMedGoogle Scholar
• Beutin, L., Aleksic, S., Zimmermann, S., and Gleier, K., Virulence factors and phenotypical traits of verotoxigenic strains of Escherichia isolated from human patients in Germany. Med. Microbiol. Immunol, 183, 13–21, 1994.
   PubMed Web of Science ®Google Scholar
• Bettelheim, K. A., Brown, J. E., Lolekha, S., and Echeverria, P., Serotypes of Escherichia coli that hybridized with DNA probes for genes encoding Shiga-like toxin I, Shiga-like toxin II, and serogroup O157 enterohemorrhagic E. coli fimbriae isolated from adults with diarrhea in Thailand.
   Google Scholar
• Yoh, M., Aoki, T., Akao, M., Sakaue, Y., Tsubura, E., and Honda, T., Report of questionnaire about enterohemorrhagic Escherichia coli cases caused in the area including Sakai City in 1996. Kansenshogaku Zasshi, 71, 1144–1154, 1997.
   PubMedGoogle Scholar
• Hara-Kudo, Y., Konuma, H., Iwaki, M., Kasuga, F., Sugita-Konishi, Y., Ito, Y., and Kumagai, S., Potential hazard of radish sprouts as a vehicle of Escherichia coli O157:H7. J. Food Protect., 60, 1125—1127, 1997.
   Web of Science ®Google Scholar
• Itoh, Y., Sugita-Konish, Kasuga, Iwaki, M., Hara-Kudo, Y., Saito, N., Noguchi, Y., Konuma, H., and Kumagai, S., Enterohemorrhagic Escherichia coli O157:H7 present in radish sprouts. Appl. Environ. Microbiol, 64, 1532–1535, 1998.
   PubMed Web of Science ®Google Scholar
• Iijima, Y., Matsumoto, M., Higuchi, K., Furuta, T., and Honda, T., Resistance to dryness of Escherichia coli O157:H7 strains from outbreak in Sakai City, Japan, 1996. Emerg. Infect. Dis., 4, 340, 1998.
   PubMed Web of Science ®Google Scholar
• Michino, H., Araki, K., Minami, S., Nakayama, T., Ejima, Y., Hiroe, K., Tanaka, H., Fujita, N., Usami, S., Yonekawa, M., Sadamoto, K., Takaya, S., and Sakai, N., Recent outbreaks of infections caused by Escherichia coli O157:H7 in Japan. In: Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains. Kaper, J. B. and O’Brien, A. D., Eds., ASM Press, Washington, D. C., 1998, 73–81.
   Google Scholar
• Goldwater, P. N. and Bettelheim, K. A., The role of enterohemorrhagic Escherichia coli serotypes other than O157:H7 as causes of disease. Communicable Disease Intelligence, 19, 2–4, 1995.
   Google Scholar
• Goldwater, P. N. and Bettelheim, K. A., An outbreak of hemolytic uremic syndrome due to Escherichia coli O157:H-: or was it? Emerg. Infect. Dis., 2, 153–154, 1996.
   PubMed Web of Science ®Google Scholar
• Lopez, E. L., Contrini, M. M., Sanz, M., Vinas, M. R., Pama, A., De Rosa, M. F., and Cleary, T. G., Perspectives on Shiga-like toxin infections in Argentina. J. Food Protect., 60, 1458–1462, 1997.
   Web of Science ®Google Scholar
• Mattar, S. and Vasquez, E., Escherichia coli O157:H7 infection in Columbia. Emerg. Infect. Dis., 4, 126–127, 1998.
   PubMed Web of Science ®Google Scholar
• Cordovez, A., Prado, V., Maggi, L., Cordero, J., Martinez, J., Misraji, A., Rios, R., Soza, G., Ojeda, A., and Levine, M. M., Enterohemorrhagic Escherichia coli associated with hemolytic-uremic syndrome in Chilean children. J. Clin. Microbiol., 30, 2153–7, 1992.
   Google Scholar
• Rowe, P. C., Orrbine, E., Lior, H., Wells, G. A., Yetisir, E., Clulow, M., and McLaine, P. N., Risk of hemolytic uremic syndrome after sporadic Escherichia coli O157:H7 infection: results of a Canadian collaborative study. Investigators of the Canadian Pediatric Kidney Disease Research Center. J. Pediatr., 132, 777–782, 1998.
   PubMed Web of Science ®Google Scholar
• Division of Disease Surveillance, Notifiable Diseases Annual Summary 1995. Canada Communicable Disease Report, 23S9, 1998.
   Google Scholar
• Orr, P., Lorencz, B., Brown, R., Kielly, R., Tan, B., Holton, D., Clugstone, H., Lugtig, L., Pim, C., MacDonald, S., et al., An outbreak of diarrhea due to verotoxin-producing Escherichia coli in the Canadian Northwest Territories. Scand. J. Infect. Dis., 26, 675–684, 1994.
   PubMed Web of Science ®Google Scholar
• Michel, P., Ph.D. dissertation. University of Guelph, Guelph, Ontario, Canada, 1997.
   Google Scholar
• Wilson, J. B., Johnson, R. P., Clarke, R. C., Rhan, K., Renwick, S. A., Alves, D., Karmali, M. A., Michel, P., Orrbine, E., and Spika, J. S., Canadian perspectives on verocytotoxin-producing Escherichia coli infection. J. Food Protect., 60, 1451–1453, 1997.
   Web of Science ®Google Scholar
• Tarr, P. I., Besser, T. E., Hancock, D. D., Keene, W. E., and Goldoft, M., Verotoxigenic Escherichia coli infection: U.S. overview. J. Food Prot., 60, 1466–1471, 1997.
   Web of Science ®Google Scholar
• Center for Disease Control and Prevention, 1997 surveillance results; CDC/USDA/FDA Foodborne Disease Active Surveillance Network. CDC’s Emerging Infections Program, Atlanta, Georgia, 1997.
   Google Scholar
• Armstrong, G. L., Hollingsworth, J., and Morris, J. G., Emerging foodborne pathogens: Escherichia coli O157:H7 as a model of entry of a new pathogen into the food supply of the developed world. Epidemol. Rev, 18, 29–51, 1996.
   PubMed Web of Science ®Google Scholar
• Toth, I., Cohen, M. L., Rumshlag, H. S., Riley, L. W., White, E. H., Carr, J. H., Bond, W. W., and Wachsmuth, I. K., Influence of the 60-megadalton plasmid on adherence of Escherichia coli O157:H7 and genetic derivatives. Infect. Immun., 58, 1223–1231, 1990.
   PubMed Web of Science ®Google Scholar
• Beutin, L., Montenegro, M. A., Orskov, I., Orskov, F., Prada, J., Zimmermann, S., and Stephan, R., Close association of verotoxin (Shiga-like toxin) production with enterohemolysin in strains of Escherichia coli. J. Clin. Microbiol., 27, 2559–2564, 1989.
   Google Scholar
• Donnenberg, M. S., Tacket, C. O., James, S. P., Losonsky, G., Nataro, J. P., Wasserman, S. S., Kaper, J. B., and Levine, M. M., Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection. J. Clin. Invest., 92, 1412–1417, 1993.
   PubMed Web of Science ®Google Scholar
• Kenny, B., Lai, L., Finlay, B. B., and Donnenberg, M. S., EspA, a protein secreted by enteropathogenic Escherichia coli, required to induce signals in epithelial cells. Mol. Microbiol, 20, 313–324, 1996.
   PubMed Web of Science ®Google Scholar
• Haigh, R., Baldwin, T., Knutton, S., and Williamns, P. H., Carbon dioxide-regulated secretion of the EaeB protein of enteropathogenic Escherichia coli. FEMS Microbiol. Lett., 129, 63–68, 1995.
   Google Scholar
• Lai, L. C., Wainwright, L. A., Stone, K. D., and Donnenberg, M. S., A third secreted protein that is encoded by the enteropathogenic Escherichia coli pathogenicity island is required for transduction of signals and for attaching and effacing activities in host cells. Infect. Immun., 65, 2211–2217, 1997.
   PubMed Web of Science ®Google Scholar
• Wadolkowski, E. A., Sung, L. M., Buris J. A., Samuel, J. E., and O’Brien, A. D., Acute renal tubular necrosis and death of mice orally infected with Escherichia coli strains that produce Shiga-like toxin type II. Infect. Immun., 58, 3959–3965, 1990.
   PubMed Web of Science ®Google Scholar
• Sjogren, R., Neil, R., Rachmilewitz, D., Fritz, D., Newland, J., Sharpnack, D., Colleton, C., Fondacaro, J., Gemski, P., and Boedeker, E., Role of Shiga-like toxin I in bacteria enteritis: comparison between isogenic Escherichia coli strains induced in rabbits. Gastroenterology, 106, 306–307, 1994.
   PubMed Web of Science ®Google Scholar
• O’Brien, A. D., LaVeck, G. D., Thompson, M. R., and Fomral, S. B., Production of Shigella dysenteriae type 1-like cytotoxin by Escherichia coli. J. Infect. Dis., 146, 763–769, 1982.
   Google Scholar
• Strockbine, N. A., Jackson, M. P., Sung, L. M., Holmes, R. K., and O’Brien, A. D., Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1. J. Bacteriol., 170, 1116–1122, 1988.
   PubMedGoogle Scholar
• Jackson, M. P., Neill, R. J., O’Brien, A. D., Holmes, R. K., and Newland, J. W., Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages from Escherichia coli 933. FEMS Microbiol. Lett, 44, 109–114, 1987.
   Web of Science ®Google Scholar
• Louise, C. B. and Obrig, T. G., Specific interaction of Escherichia coli O157:H7-derived Shiga-like toxin II with human renal endothelial cells. J. Infect. Dis., 172, 1397–1401, 1995.
   PubMed Web of Science ®Google Scholar
• Scotland, S. M., Willshaw, G. A., Smith, H R., and Rowe, B., Properties of strains of Escherichia coli belonging to serogroup O157 with special reference to production of Vero cytotoxin VT1 and VT2. Epidemiol. Infect, 99, 613–624, 1987.
   PubMed Web of Science ®Google Scholar
• Endo, Y., Tsurugi, K., Yutsudo, T., Takeda, Y., Ogasawara, T., and Igarashi, K., Site of action of a verotoxin (VT2) from Escherichia coli O157:H7 and of Shiga-like toxin on eukaryotic ribosomes. Eur. J. Biochem., 171, 45–50, 1988.
   PubMedGoogle Scholar
• Sandvig, K., Garred, O., Prydz, K., Kozlov, J. V., Hansen, S. H., and van Deurs, B., Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature, 358, 510–512, 1992.
   PubMed Web of Science ®Google Scholar
• Sandvig, K and van Deurs, B., Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin. Physiol. Rev., 76, 949–966, 1996.
   PubMed Web of Science ®Google Scholar
• Schmidt, H., Maier, E., Karch, H., and Benz, R., Pore-forming properties of the plasmid-encoded hemolysin of enterohemorrhagic Escherichia coli O157:H7. Eur. J. Biochem, 241, 594–601, 1996.
   PubMedGoogle Scholar
• Schmidt, H., Beutin, L., and Karch, H., Molecular analyses of the plasmid-encoded heomlysin of Escherichia coli O157:H7 strain EDL 933. Infect. Immun, 63, 1055–1061, 1995.
   PubMed Web of Science ®Google Scholar
• Brunder, W., Schmidt, H., and Karch, H., EspP, a novel extracellular serine protease of entero-hemor-rhagic Escherichia coli O157:H7 cleaves human coagulation factor V. Mol. Microbiol., 24, 767–78, 1997.
   PubMed Web of Science ®Google Scholar
• Elliott, S. J., Wainwright, L. A., McDaniel, T. K., Jarvis, K. G., Deng, Y. K., Lai, L. C., McNamara, B. P., Donnenberg, M. S., and Kaper, J. B., The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol. Microbiol, 28, 1–4, 1998.
   PubMed Web of Science ®Google Scholar
• Perna, N. T., Mayhew, G. F., Posfai, G., Elliott, S. J., Donnenberg, M. S., Kaper, J. B., and Blattner, F. R., Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157:H7. Infect. Immun., 66, 3810–3817, 1998.
   PubMed Web of Science ®Google Scholar
• Jerse, A. E., Yu, J., Tall, B. D., and Kaper, J. B., A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells. Proc. Natl. Acad. Sci. U.S.A., 87, 7839–7843, 1990.
   PubMed Web of Science ®Google Scholar
• Rosenshine, I., Ruschkowski, S., Stein, M., Reinscheid, D., Mills, S. D., and Finlay, B. B., A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation. EMBO J., 15, 2613–2624, 1996.
   PubMed Web of Science ®Google Scholar
• Frankel, G., Lider, O., Hershkoviz, R., Mould, A. P., Kachalsky, S. G., Candy, D. C. A., Cahalon, L., Humphries, M. J., and Dougan, G., The cell-binding domain of intimins from enteropathogenic Escherichia coli binds to β1 integrins. J. Biol. Chem., 271, 20359–20364, 1996.
   PubMed Web of Science ®Google Scholar
• Foubister, V., Rosenshine, I., Donnenberg, M. S., and Finlay, B. B., The eaeB gene of enteropathogenic Escherichia coli (EPEC) is necessary for signal transduction in epithelial cells. Infect. Immun., 62, 3038–3040, 1994.
   PubMed Web of Science ®Google Scholar
• Ebel, F., Deibel, C., Kresse, A. U., Guzman, G. A., and Chakraborty, T., Temperature- and medium-dependent secretion of proteins by Shiga toxin-producing Escherichia coli. Infect. Immun, 64, 4472–4479, 1996.
   Google Scholar
• Jarvis, K. G. and Kaper, J. B., Secretion of extracellular proteins by enterohemorrhagic Escherichia coli via a putative type III secretion system. Infect. Immun., 64, 4826–4829, 1996.
   PubMedGoogle Scholar
• Jarvis, K. G., Giron, J. A., Jerse, A. E., McDaniel, T. K., Donnenberg, M. S., and Kaper, J. B., Enteropathogenic Escherichia coli contains a specialized secretion system necessary for the export of proteins involved in attaching and effacing lesion formation. Proc. Natl. Acad. Sci. U.S.A., 92, 7996–8000, 1995.
   Google Scholar
• Lee, C. A., Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells? Trends Microbiol, 5, 148–156, 1997.
   PubMed Web of Science ®Google Scholar
• Perry, M. B., Bundle, D. R., Gidney, M. A., and Lior, H., Identification of Escherichia coli serotype O157 strains by using a monoclonal antibody. J. Clin. Microbiol., 26, 2391–2394, 1998.
   Google Scholar
• Paton, A. W., Voss, E., Manning, P. A., and Paton, J. C., Antibodies to lipopolysaccharide block adherence of Shiga toxin-producing Escherichia coli to human intestinal epithelial (Henle 407) cells. Microb. Pathog, 24, 57–63, 1998.
   PubMed Web of Science ®Google Scholar
• Cohen, M. B. and Giannella, R. A., Hemorrhagic colitis associated with Escherichia coli O157:H7., Adv. Internal. Med, 37, 173–195, 1992.
   Google Scholar
• Pudden, D., Tuttle, N., Korn, D., Carlson, J., Carter, A., and Hockin, H., Hemorrhagic colitis in a nursing home—Ontario. Can. Dis. Wkly. Rep., 11, 169–170, 1985.
   Google Scholar
• Crinnantonio, C., Vitacco, M., Mendilaharzu, F., Rutty, A., and Mendilaharazie, J., The hemolyticuremic syndrome. J. Pediatr., 64, 478–491, 1964.
   PubMedGoogle Scholar
• Siegler, R. L., The hemolytic uremic syndrome. Pediatr. Clin. N. Am., 42, 1505–1529, 1995.
   PubMed Web of Science ®Google Scholar
• Rose, P. E., Armour, J. A., Williams, C. E., and Hill, F. G., Verotoxin and neuraminidase induced platelet aggregation activity in plasma: their possible role in the pathogenesis of the haemolytic uraemic syndrome. J. Clin. Pathol., 38, 438–441, 1985.
   PubMed Web of Science ®Google Scholar
• Xu, Y., Hagege, J., Mougnot, B., Sraer, J., Ronne, E., and Rondeau, E., Different expression of the plasminogen activation system in renal thrombotic microangiopathy and the normal human kidney. Kidney Int., 50, 2011–2019, 1996.
   PubMed Web of Science ®Google Scholar
• Rowe, P. C., Orrbine, E., Wells, G. A., and McLaine, P., Epidemiology of the hemolytic uremic syndrome in Canadian children from 1986–1988. J. Pediatr., 119, 218–224, 1991.
   PubMed Web of Science ®Google Scholar
• Van Setten, P. A., van Hinsbergh, V. W., van den Heuvel, L. P., van der Velden, T. J., van der Kar, N. C., Krebbers, R. J., Karmali, M. A., and Monnens, L. A., Verocytotoxin inhibits mitogenesis and protein synthesis in purified human glomerular mesangial cells without affecting cell viability: evidence for two distinct mechanisms. J. Am. Soc. Nephrol, 8, 1877–1888, 1997.
   PubMed Web of Science ®Google Scholar
• Cleary, T. G., Cytotoxin-producing Escherichia coli and the hemolytic uremic syndrome. Pediatr. Clin. N. Am., 35, 485–501, 1988.
   PubMed Web of Science ®Google Scholar
• Machin, S. J., Clinical annotation: thrombotic thrombocytopenic purpura. Br. J. Hematol., 56, 191–197, 1984.
   PubMedGoogle Scholar
• Proesmans, W., Typical and atypical hemolytic uremic syndrome. Kidney Blood Press. Res., 19, 205–208, 1996.
   PubMed Web of Science ®Google Scholar
• Padhye, N. V. and Doyle, M. P., Escherichia coli O157:H7: epidemiology, pathogenesis, and methods for detection in food. J. Food Protect., 55, 555–565, 1992.
   PubMed Web of Science ®Google Scholar
• Wells, J. G., Shipman, L. D., Greence, K. D., Sowers, S. M., Green, J. H., Cameron, D. N., Downes, F.P., Martin, M. L., Griffin, P. M., Ostroff, S. M., Potter, M E., Tauxe, R. V., and Wachsmuth, I K., Isolation of Escherichia coli O157:H7 and other Shiga-like-toxin-producing E. coli from dairy cattle. J. Clin. Microbiol. 29, 985–989, 1991.
   PubMed Web of Science ®Google Scholar
• Rahn, K., Renwick, S. A., Johnson, R. P., Wilson, J. B., Clarke, R. C., Alves, D., McEwen, S., Lior, H., and Spika, J., Persistence of Escherichia coli O157:H7 in dairy cattle and the dairy farm environment. Epidemiol. Infect., 119, 251–259, 1997.
   PubMed Web of Science ®Google Scholar
• Renwick, S. A., Wilson, J. B., Clarke, R. C., Loir, H., Borezyk, A. A., Spika, J., Rhan, K., McFadden, K., Brouwer, A., Copps, A., Anderson, N. G., Alves, D., and Karmali, M A., Evidence of direct transmission of Escherichia coli O157:H7 infection between calves and a human. J. Infect. Dis., 168, 792–793, 1993.
   PubMed Web of Science ®Google Scholar
• Chapman, P. A., Siddons, C. A., Gerdan Malo, A.T., and Harkin, M A., A 1-year study of Escherichia coli O157 in cattle, sheep, pigs and poultry. Epidemiol. Infect, 119, 245–250, 1997.
   PubMed Web of Science ®Google Scholar
• Hancock, D. D., Besser, T. E., and Rice, D. H., Ecology of Escherichia coli O157:H7 in cattle and impact of management practice. In Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains. Kaper, J. B. and O’Brien, A. D., Eds., ASM Press, Washington, D.C., 1998, 85–91.
   Google Scholar
• Hinton, M., Linton, A. H., and Hedges, A. J., The ecology of Escherichia coli in calves reared as dairy-cow replacements. J. Appl. Bacteriol., 58, 131–138, 1985.
   PubMedGoogle Scholar
• Cary, W. C. and Moon, H W., Experimental infection of calves and adult cattle with Escherichia coli O157:H7. Appl. Environ. Microbiol, 61, 1586–1590, 1995.
   PubMed Web of Science ®Google Scholar
• Brown, C. A., Harmon, B. G., Zhao, T., and Doyle, M P., Experimental Escherichia coli O157:H7 carriage in calves. Appl. Environ. Microbiol., 63, 27–32, 1997.
   PubMed Web of Science ®Google Scholar
• Dean-Nystrom, E. A., Bosworth, B. T., and Moon, H W., Pathogenesis of O157:H7 Escherichia coli infection in neonatal calves. Adv. Exp. Med. Biol., 412, 47–51, 1997.
   PubMed Web of Science ®Google Scholar
• Faith, N. G., Shere, J. A., Brosch, R., Arnold, K. W., Ansay, S. E., Lee, M S., Luchansky, J. B., and Kaspar, C. W., Prevalence and clonal nature of Escherichia coli O157:H7 on dairy farms in Wisconsin. Appl. Environ. Microbiol, 62, 1519–1525, 1996.
   PubMed Web of Science ®Google Scholar
• LeJeune, J., Hancock, D. D., and Besser, T. E., Escherichia coli O157:H7 in cattle water troughs: a possible on-farm reservoir, abstr. 2. In Abstracts of the fifth annual food safety farm to table conference, Northwest Food Safety Consortium. Northwest food safety consortium, Moscow, Idaho, 1997.
   Google Scholar
• Lynn, T. V., Hancock, D. D., Besser, T. E., Harrsion, J. H., Rice, D. H., Stewart, N. T., and Rowan, L. L., The occurrence and replication of Escherichia coli in cattle feeds. J. Dairy Sci., 81, 1102–1108, 1998.
   PubMed Web of Science ®Google Scholar
• Diez-Gonzalez, F., Callaway, T. R., Kizoulis, M. G., and Russell, J. B., Grain-feeding and the dissemination of acid-resistant Escherichia coli from cattle. Science, 281, 1666–1668, 1998.
   PubMed Web of Science ®Google Scholar
• Besser, R. E., Lett, S., Weber, J., Doyle, M P., Barrett, T., Wells, J. G., and Griffin, P., An outbreak of diarrhea and hemolytic uremic syndrome from Escherichia coli O157:H7 in fresh pressed apple cider. JAMA, 269, 2217–2220, 1993.
   PubMed Web of Science ®Google Scholar
• Raghubeer, E. V. and Matches, J. R., Temperature range for growth of Escherichia coli serotype O157:H7 and selected coliforms in E. coli medium. J. Clin. Microbiol. 28, 803–805, 1990.
   PubMed Web of Science ®Google Scholar
• Juneja, V. K., Snyder, O. P., and Marmer, B. S., Thermal destruction of Escherichia coli O157:H7 in beef and chicken: determination of D- and z-values. Int. J. Food Microbiol, 35, 231–237, 1997.
   PubMed Web of Science ®Google Scholar
• Leyer, J. E., Fain, A. R., Moran, A. B., Martin, L. M., Lechowich, R. V., Carosella, J. M., and Brown, W. L., Lethality of heat to Escherichia coli O157:H7: D-value and z-value determination in ground beef. J. Food Protect, 54, 762–766, 1991.
   Web of Science ®Google Scholar
• Kaur, J., Ledward, D. A., Park, R. W., and Robinson, R. L., Factors affecting the heat resistance of Escherichia coli O157:H7. Lett. Appl. Microbiol., 26, 325–330, 1998.
   PubMed Web of Science ®Google Scholar
• Zhao, T., Doyle, M. P., and Besser, R. E., Fate of enterohemorrhagic Escherichia coli O157:H7 in apple cider with and without preservatives. Appl. Environ. Microbiol., 59, 2526–2530, 1993.
   PubMed Web of Science ®Google Scholar
• Keene, W. E., Sazie, E., Kok, J., Rice, D. H., Hancock, D. D., Balan, V. K., Zhao, T., and Doyle, M. P., An outbreak of Escherichia coli O157:H7 infections traced to jerky made from deer meat. JAMA, 277, 1229–1233, 1997.
   PubMed Web of Science ®Google Scholar
• Massa, S., Altieri, C., Quanta, V., and De Pace, R., Survival of Escherichia coli O157:H7 in yogurt during preparation and storage at 4°C. Lett. Appl. Microbiol, 24, 347–350, 1997.
   PubMed Web of Science ®Google Scholar
• Gorden, J. and Small, P. L., Acid resistance in enteric bacteria. Infect. Immun., 61, 364–367, 1993.
   PubMed Web of Science ®Google Scholar
• Lang, R. and Henge-Aronis, R., Identification of a central regulator of stationary-phase gene expression in Escherichia coli. Mol. Microbiol., 5, 49–59, 1991.
   Google Scholar
• Raja, N., Goodson, M., Chul, W. C. M., Smith, D. G., and Rowbury, R. J., Habituation to acid in Escherichia coli: conditions for habituation and its effects on plasmid transfer. J. Appl. Bacteriol., 79, 59–65, 1991.
   Google Scholar
• Arnold, K W. and Kaspar, C. W., Starvation- and stationary-phase-induced acid tolerance in Escherichia coli O157:H7. Appl. Environ. Microbiol, 61, 2037–2039, 1995.
   PubMed Web of Science ®Google Scholar
• Lin, J., Smith, M. P., Chapin, K C., Baik, H S., Bennett, G. N., and Foster, J. W., Mechanims of acid resistance in enterohemorrhagic Escherichia coli. Appl. Environ. Microbiol., 62, 3094–3100, 1996.
   Google Scholar
• Glass, K A., Loeffelholz, J. M., Ford, J. P., and Doyle, M P., Fate of Escherichia coli O157:H7 as affected by pH or sodium chloride and in fermented, dry sausage. Appl. Environ. Microbiol., 58, 2513–2516, 1992.
   PubMed Web of Science ®Google Scholar
• Anon. Escherichia coli O157:H7 outbreak linked to commercially distributed dry-cured salami—Washington and California, 1994. Morb. Mortal. Wkly. Rep., 44, 157–160, 1995.
   PubMedGoogle Scholar
• Dev, V. J., Main, M., and Gould, I., Waterborne outbreak of Escherichia coli O157. Lancet, 337, 1412, 1991.
   PubMed Web of Science ®Google Scholar
• Keene, W. E., McAnulty, J. M., Hoesly, F. C., Williams, P., Hedberg, K., Oxman, G. L., Barrett, T. J., Pfaller, M. A., and Fleming, D. W., A swimming-associated outbreak of hemorrhagic colitis caused by Escherichia coli O157:H7 and Shigella sonnei. N. Engl. J. Med, 277, 1229–1231, 1994.
   Google Scholar
• Ackman, D., Marks, S., Mack, P., Caldwell, M., Root, T., and Birkhead, G., Swimming-associated haemorrhagic colitis due to Escherichia coli O157:H7 infection: evidence of prolonged contamination of a fresh water lake. Epidemiol. Infect., 119, 1–8, 1997.
   PubMed Web of Science ®Google Scholar
• Wang, G., Zhao, T., and Doyle, M P., Fate of enterohemorrhagic Escherichia coli O157:H7 in bovine feces. Appl. Environ. Microbiol., 62, 2567–2570, 1996.
   PubMed Web of Science ®Google Scholar
• Wang, G. and Doyle, M. P., Survival of entero-hemorrhagic Escherichia coli O157:H7 in water. J. Food Protect., 61, 662–667, 1998.
   PubMed Web of Science ®Google Scholar
• Masaki, H., Tokumaru, Y., Itaya, T., Aoki, A., Saitoh, A., Andoh, K., Nose, N., and Katabami, J., Investigation of pathogenic Escherichia coli. Pollution of well water and its survival in various kinds of water. Japan. J. Food Microbiol, 9, 51–57, 1992.
   Google Scholar
• Food and Drug Administration, Food code: 1997. U. S. Department of Health and Human Services, Washington, D.C., 1997.
   Google Scholar
• Jackson, T., Mardin, M., and Acuff, G., Heat resistance of Escherichia coli O157:H7 in a nutrient medium and in ground beef patties as influenced by storage and holding temperatures. J. Food Protect., 59, 230–237, 1996.
   PubMed Web of Science ®Google Scholar
• Delazari, I., Iaria, S. T., Riemann, H P., Cliver, D. O., and Mori, T., Decontaminating beef for Escherichia coli O157:H7. J. Food Protect., 61, 547–550, 1998.
   PubMed Web of Science ®Google Scholar
• Blaszyk, M. and Holley, R. A., Interaction of monolaurin, eugenol and sodium citrate on growth of common meat spoilage and pathogenic organisms. Int. J. Food Microbiol, 39, 175–183, 1998.
   PubMed Web of Science ®Google Scholar
• Brashears, M M., Reilly, S. S., and Gilliland, S. E., Antagonistic action of cells of Lactobacillus lactis toward Escherichia coli O157:H7 on refrigerated raw chicken meat. J. Food Protect., 61, 166–170, 1998.
   PubMed Web of Science ®Google Scholar
• Fratamico, P. M. and Cooke, P. H., Isolation of Bdellovibrios that prey on Escherichia coli O157:H7 and Salmonella species and application for removal of prey from stainless steel surfaces. J. Food Safety, 16, 161–173, 1996.
   Web of Science ®Google Scholar
• Anon., Department of Agriculture Food Safety and Inspection Services 9CFR part 381 final rule: irradiation of poultry products. Fed. Regist., 57, 43588–43600, 1992.
   Google Scholar
• Anonymous, FDA approves meat irradiation for pathogen control. Public Health Rep., 113, 105, 1998.
   PubMed Web of Science ®Google Scholar
• Thayer, D. W. and Boyd, G., Elimination of Escherichia coli O157:H7 in meats by gamma irradiation. Appl. Environ. Microbiol, 59, 1030–10340, 1993.
   PubMed Web of Science ®Google Scholar
• Bitzan, M., Ludwig, K., Klemt, M., Konig, H., Buren, J., and Muller-Wiefel, D. E., The role of Escherichia coli O157 infections in the classical (enteropathic) haemolytic uraemic syndrome: results of a Central European, multicenter study. Epidemiol. Infect., 11, 183–196, 1993.
   Google Scholar
• Chapman, P. A., Siddons, C. A., Zadik, P. M., and Jewes, L., An improved selective medium for the isolation of Escherichia coli O157. J. Med. Microbiol., 35, 107–10, 1991.
   PubMed Web of Science ®Google Scholar
• Zadik, P. M., Chapman, P. A., and Siddons, C. A., Use of tellurite for the selection of verocytotoxigenic Escherichia coli O157. J. Med. Microbiol., 39, 155–158, 1993.
   PubMed Web of Science ®Google Scholar
• MacRae, M., Rebate, T., Johnston, M., and Ogden, I. D., The sensitivity of Escherichia coli O157 to some antimicrobials by conventional and conductance assays. Lett. Appl. Microbiol., 25, 135–7, 1997.
   PubMed Web of Science ®Google Scholar
• Scotland, S. M., Cheasty, T., Thomas, A., and Rowe, B., Beta-glucuronidase activity of Vero cytotoxin-producing strains of Escherichia coli, including serogroup O157, isolated in the United Kingdom. Lett. Appl. Microbiol, 13, 42–44, 1991.
   Web of Science ®Google Scholar
• Konolwalchuk, J., Speirs, J. I., and Stavic, S., Vero response to a cytotoxin of Escherichia coli. Infect. Immun., 18, 775–779, 1977.
   Google Scholar
• Lindgren, S. W., Samuel, J. E, Schmitt, C. K., and O’Brien, A. D., The specific activities of Shiga-like toxin type II (SLT-II) and SLT-II-related toxins of enterohemorrhagic Escherichia coli differ when measured by Vero cell cytotoxicity but not by mouse lethality. Infect. Immun., 62, 623–631, 1994.
   PubMed Web of Science ®Google Scholar
• Johnson, R. P., Durham, R. J., Johnson, S. T., MacDonald, L. A., Jeffrey, S. R., and Butman, B. T., Detection of Escherichia coli O157:H7 in meat by an enzyme-linked immunosorbent assay, EHEC-Tek. Appl. Environ. Microbiol, 61, 386–388, 1995.
   PubMed Web of Science ®Google Scholar
• Chapman, P. A., Malo, A. T., Siddon, C. A., and Harkin, M., Use of commercial enzyme immunoassays and immunomagnetic separation systems for detecting Escherichia coli O157 in bovine fecal samples. Appl. Environ. Microbiol., 63, 2549–2553, 1997.
   PubMed Web of Science ®Google Scholar
• Borczyk, A. A., Harnett, N., Lombos, M., and Lior, H., False-positive identification of Escherichia coli O157:H7 by commercial latex agglutination tests. Lancet, 336, 946–947, 1990.
   PubMed Web of Science ®Google Scholar
• Bennett, A. R., MacPhee, S., and Betts, R. P., The isolation and detection of Escherichia coli O157 by use of immunomagnetic separation and immunoassay procedures. Lett. Appl. Microbiol., 22, 237–243, 1996.
   PubMed Web of Science ®Google Scholar
• Brewster, J. D. and Mazenko, R. S., Filtration capture and immunoelectrochemical detection for rapid assay of Escherichia coli O157:H7. J. Immunol. Methods, 211, 1–8, 1998.
   PubMed Web of Science ®Google Scholar
• Yu, H. and Bruno, J. G., Immunomagnetic-electrochemiluminescent detection of Escherichia coli O157 and Salmonella typhimurium in foods and environmental water samples. Appl. Environ. Microbiol. 62, 587–592, 1996.
   PubMed Web of Science ®Google Scholar
• Czajka, J. and Batt, C. A., A solid phase fluorescent capillary immunoassay for the detection of Escherichia coli O157:H7 in ground beef and apple cider. J. Appl. Bacteriol., 81, 601–607, 1996.
   PubMedGoogle Scholar
• Gannon, V. P., Rashed, M., King, R. K., and Thomas, E. J., Detection and characterization of the eae gene of Shiga-like toxin-producing Escherichia coli using polymerase chain reaction. J. Clin. Microbiol., 31, 1268–1274, 1993.
   PubMed Web of Science ®Google Scholar
• Schmidt, H., Montag, M., Bockemuhl, J., Heesemann, J., and Karch, H., Shiga-like toxin II-related cytotoxins in Citrobacter freundii strains from humans and beef samples. Infect. Immun., 61, 534–543, 1993.
   PubMed Web of Science ®Google Scholar
• Feng, P., Identification of Escherichia coli O157:H7 by DNA probes specific for an allele of uidA gene. Mol. Cell. Probes, 7, 151–154, 1993.
   PubMed Web of Science ®Google Scholar
• Cebula, T. A., Payne, W. L., and Feng, P., Simultaneous identification of Escherichia coli of the O157:H7 serotype and their Shiga-like toxin type by MAMA/multiplex PCR. J. Clin. Microbiol., 53, 248–250, 1995.
   Google Scholar
• Fratamico, P. M., Sackitey, S. K., Wiedmann, M., and Deng, M. Y., Detection of Escherichia coli O157:H7 by multiplex PCR. J. Clin. Mcirobiol., 33, 2188–2191, 1995.
   PubMed Web of Science ®Google Scholar
• Meng, J., Zhao, S., Doyle, M. P., Mitchell, S., and Kresovich, S., A multiplex PCR for identifying Shiga-like toxin-producing Escherichia coli O157:H7. Lett. Appl. Microbiol, 24, 172–176, 1997.
   PubMed Web of Science ®Google Scholar